Daño al ADN / Reparación del ADN
Los inhibidores de daño/ reparación del ADN son compuestos que interfieren con los procesos involucrados en la detección y reparación de daños en el ADN. Estos inhibidores son fundamentales para estudiar los mecanismos de estabilidad genómica, mutagénesis y respuesta al daño del ADN. También son importantes en la investigación del cáncer, ya que muchos tumores dependen de vías específicas de reparación del ADN para sobrevivir. Al inhibir estas vías, los inhibidores de daño/reparación del ADN pueden aumentar la eficacia de la quimioterapia y la radioterapia. En CymitQuimica, ofrecemos una amplia gama de inhibidores de daño/reparación del ADN de alta calidad para apoyar su investigación en biología molecular, oncología y farmacología.
Subcategorías de "Daño al ADN / Reparación del ADN"
- ATM / ATR(71 productos)
- Alquilación de ADN(11 productos)
- ADN metiltransferasa(422 productos)
- ADN girasa(11 productos)
- ADN-PK(51 productos)
- MTH1(1 productos)
- Antimetabolito / análogo nucleósido(1.388 productos)
- Transcriptasa inversa(43 productos)
- Sirtuin(88 productos)
- Telomerasa(33 productos)
- Topoisomerasa(136 productos)
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Se han encontrado 958 productos de "Daño al ADN / Reparación del ADN"
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TAK1 inhibitor
CAS:<p>TAK1 inhibitor is an inhibitor, which can inhibit MCF-7, A549, DU-145 and MDA MB-231, with IC50 of 0.021, 0.14, 0.064 and 0.19, respectively.</p>Fórmula:C22H19ClN6O2SPureza:98%Forma y color:SoildPeso molecular:466.94(±)4(5)-DiHDPA lactone
CAS:<p>(±)5(6)-DiHET lactone is a 1,5 cyclic ester derived from (±)5(6)-DiHET , which, in turn, is a potential derivative of epoxidation of arachidonic acid at the α-5</p>Fórmula:C22H32O3Forma y color:SolidPeso molecular:344.495SMPB Crosslinker
CAS:<p>SMPB crosslinker reacts with sulfhydryl/amino groups, has a longer chain than MBS, and a non-cleavable spacer arm.</p>Fórmula:C18H16N2O6Pureza:98%Forma y color:SolidPeso molecular:356.33CAY10599
CAS:<p>CAY10599 has a wide range of applications in life science related research.</p>Fórmula:C38H41NO5Forma y color:SolidPeso molecular:591.748WAY-323061
CAS:<p>WAY-323061 is a SIRT2 inhibitor.</p>Fórmula:C25H21N5O2SPureza:99.33%Forma y color:SolidPeso molecular:455.53NHC-triphosphate tetrasodium
<p>NHC-triphosphate tetrasodium, a metabolite of β-d-N4-Hydroxycytidine, acts as a viral polymerase substrate affecting HCV RNA replication.</p>Fórmula:C9H12N3Na4O15P3Forma y color:SolidPeso molecular:587.08Tibesaikosaponin V
CAS:<p>TKV, a triterpene diglycoside from Bupleurum chinense, curbs lipid build-up and fat content in adipocytes without harm and hinders fat cell differentiation.</p>Fórmula:C42H68O15Forma y color:SolidPeso molecular:812.98DNMT1/HDAC-IN-1
<p>DNMT1/HDAC-IN-1 (compound (R)-23a), a potent dual inhibitor targeting both DNMT1 and HDAC, exhibits impressive inhibitory effects specifically on HDAC1 (HDAC1:IC50=0.05 μM), a major HDAC isoform that interacts with DNMT1 across multiple protein complexes involved in the transcriptional silencing of TSGs. This compound has been shown to remodel the tumor immune microenvironment and induce tumor regression, effectively reversing cancer-specific epigenetic abnormalities.</p>Forma y color:Odour SolidGJ071 oxalate
CAS:<p>GJ071 oxalate is a Nonsense suppressor that induces readthrough by inserting amino acids at premature termination codons.</p>Fórmula:C20H29N3O7SPureza:99.97%Forma y color:SolidPeso molecular:455.53DNA Damage & Repair Compound Library
<p>A unique collection of xnum DNA Damage &amp; Repair related compounds for high throughput screening (HTS) and high content screening (HCS);</p>Forma y color:Odour SolidZ26395438
CAS:<p>Z26395438 is an inhibitor of Sirtuin-1 with IC50 of 1.6 μM.</p>Fórmula:C17H15FN2OPureza:99.63%Forma y color:SolidPeso molecular:282.31SJ-106C
<p>SJ-106C, a SIRT inhibitor, exhibits IC50 values of 0.59, 0.12, and 0.49 μM against SIRT1/2/3, respectively. This compound specifically targets mitochondria and inhibits the growth of DLBCL tumors.</p>Forma y color:Odour SolidHippeastrine
CAS:<p>Hippeastrine is an alkaloid that inhibits Top I dose-dependently with a 7.25 μg/mL IC50 and has anticancer properties.</p>Fórmula:C17H17NO5Forma y color:SolidPeso molecular:315.32CP 84364
CAS:<p>CP 84364 is a metabolite of CP-80794.</p>Fórmula:C14H18N2O4Forma y color:SolidPeso molecular:278.30CUDA disodium
<p>CUDA disodium is an effective, soluble epoxide hydrolase (sEH) inhibitor, with IC50 values of 11.1 nM for murine sEH and 112 nM for human sEH. It selectively enhances the activity of peroxisome proliferator-activated receptor PPARalpha. CUDA disodium may be valuable for cardiovascular disease research.</p>Forma y color:Odour SolidSP4e
<p>SP4e is a PPAR-γ activator.SP4e was effective in decreasing blood glucose, total cholesterol, triglycerides and LDL levels and increasing HDL levels.</p>Fórmula:C22H17ClN2O2S2Pureza:99.79%Forma y color:SoildPeso molecular:440.97Methylation Compound Library
<p>xnum methylation-related compounds that can be used for high-throughput and high-content screening.</p>Forma y color:Odour SolidHDAC-IN-78
<p>HDAC-IN-78 (compound 66a) is an HDAC inhibitor utilized for cancer research.</p>Forma y color:Odour Solid(±)9-HEPE
CAS:<p>(±)9-HEPE is produced by non-enzymatic oxidation of EPA.</p>Fórmula:C20H30O3Forma y color:SolidPeso molecular:318.457NHC-diphosphate triammonium
<p>NHC-triphosphate triammonium is a phosphorylated metabolite of NHC, incorporated into HCV RNA by viral polymerase.</p>Forma y color:Solid
