ADN metiltransferasa
Las metiltransferasas de ADN (DNMT) son enzimas que catalizan la adición de grupos metilo a los residuos de citosina en el ADN, lo que lleva al silenciamiento génico. La metilación aberrante del ADN está asociada con diversas enfermedades, incluido el cáncer. Los inhibidores de DNMT bloquean la actividad de estas enzimas, lo que lleva a la reactivación de genes silenciados y la inducción de apoptosis en células cancerosas. Los inhibidores de DNMT se utilizan ampliamente en la investigación epigenética y la terapia contra el cáncer. En CymitQuimica, ofrecemos una gama de inhibidores de DNMT de alta calidad para apoyar su investigación en epigenética, metilación del ADN y biología del cáncer.
Se han encontrado 457 productos de "ADN metiltransferasa"
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PROTAC EED degrader-1
PROTAC EED degrader-1 is a PROTAC targeting EED (pKD = 9.02), is a inhibitor of polycomb repressive complex 2 (PRC2) with pIC50 of 8.17.Fórmula:C55H60FN11O8SPureza:98%Forma y color:SolidPeso molecular:1054.2TB22
TB22 is a non-nucleoside inhibitor of DOT1LR231Q with anticancer activity. It inhibits the malignant phenotype of lung cancer cells harboring the R231Q mutation via the MAPK/ERK signaling pathway, making it useful for lung cancer research.Forma y color:Odour SolidA-893
CAS:A-893 is a cell-active inhibitor of Methyltransferase SMYD2 (IC 50 = 2.8 nM) .Fórmula:C29H38Cl2N4O4Forma y color:SolidPeso molecular:577.54UNC4976
UNC4976 is a positive allosteric modulator (PAM) peptidomimetic of CBX7 chromodomain binding to nucleic acids.Fórmula:C47H70N6O8Pureza:98%Forma y color:SolidPeso molecular:847.09PROTAC EED degrader-2
PROTAC EED degrader-2 is a PROTAC targeting EED (pKD of 9.27),is a inhibitor of polycomb repressive complex 2 (PRC2) with pIC50 of 8.11.Fórmula:C50H58FN11O6SPureza:98%Forma y color:SolidPeso molecular:960.13EZH2-IN-22
CAS:EZH2-IN-22 (example 92) is a potent EZH2 inhibitor, exhibiting IC50 values of <0.00051 µM for EZH2(Y641N) and EZH2(Y641F), and 0.00052 µM for EZH2 (wt). Additionally, EZH2-IN-22 demonstrates antiproliferative activity.Fórmula:C36H50N4O8Forma y color:SolidPeso molecular:666.8PRMT5-IN-34
PRMT5-IN-34 (Compound C) is an inhibitor of MTA-cooperative protein arginine methyltransferase 5 (PRMT5/MAT).Fórmula:C23H19F2N5O2Peso molecular:435.15068PRMT5-IN-12
CAS:PRMT5-IN-12 shows remarkable inhibitory activity on PRMT5 .Fórmula:C32H40N4O4Forma y color:SolidPeso molecular:544.696EPZ-719
CAS:EPZ-719: Potent SETD2 inhibitor, IC50=0.005μM, high selectivity, potential for targeted epigenetic therapy.Fórmula:C22H31FN4O3SForma y color:SolidPeso molecular:450.57MC3343
CAS:MC3343, a DNMT1/3A inhibitor, affects tumor proliferation by blocking osteosarcoma cells in the G1 or G2/M phase and induces osteogenic differentiation.Fórmula:C27H23N7OPureza:99.73%Forma y color:SolidPeso molecular:461.52PRMT4-IN-3
PRMT4-IN-3 (compound 56) serves as a potent class I protein arginine methyltransferase (PRMT) inhibitor, specifically targeting PRMT4 with an IC50 value of 37
Fórmula:C23H29N7OPureza:98%Forma y color:SolidPeso molecular:419.52BML-278
CAS:BML-278 is a SIRT1 activator with an EC150 of 1 μM.BML-278 increases H3K9 methylation and inhibits H3K9 acetylation in parental and maternal prokaryotes, andFórmula:C24H25NO4Pureza:99.98%Forma y color:SolidPeso molecular:391.46ND-L11B free base
ND-L11B is an effective degrader of the nuclear receptor binding SET domain protein 2 (NSD2) and RE-IIBP, with DC50 values of 1.48 μM and 0.8 μM, respectively, and a Dmax close to 80%.Fórmula:C37H51F3N10O2Forma y color:SolidPeso molecular:724.862ORIC-944 TFA
ORIC-944 TFA is an orally bioavailable selective polycomb repressive complex 2 (PRC2) inhibitor with antitumor activity.Fórmula:C28H26F4N6O3Forma y color:SoildPeso molecular:570.54MAK-683 hydrochloride
CAS:MAK683 hydrochloride is an inhibitor of embryonic ectoderm development (EED), with IC50 values of 59, 26nM measured in EED Alphascreen, ELISA.Cost-effective and quality-assured.Fórmula:C20H18ClFN6OPureza:97.02% - >99.99%Forma y color:SolidPeso molecular:412.85Dot1L-IN-1 TFA
Dot1L-IN-1 TFA: potent inhibitor, K i =2 pM, IC 50 <0.1 nM; reduces H3K79 dimethylation (IC 50 =3 nM) & HoxA9 promoter activity (IC 50 =17 nM).Fórmula:C34H37ClF3N9O4SForma y color:SolidPeso molecular:760.23FTX-6058 hydrochloride
CAS:FTX-6058 hydrochloride is a potent EED inhibitor, induces HbF, and aids sickle cell and β-thalassemia research.Fórmula:C22H19ClFN5O2Forma y color:SolidPeso molecular:439.87PRMT5-IN-36
CAS:PRMT5-IN-36 (compound 4), an orally active PRMT5 inhibitor, is utilized in cancer research studies.Fórmula:C20H15F3N6O2Peso molecular:428.37PRMT5-MTA-IN-2
PRMT5-MTA-IN-2 (compound 1) is a synergistic inhibitor of PRMT5 with an IC50 of less than 1.5 nM.Fórmula:C30H25F2N7O2Forma y color:SolidPeso molecular:553.56SETD7-IN-1
SETD7-IN-1 (compound 7), a PFI-2 analogue, acts as both a substrate and inhibitor of histone lysine methyltransferase SETD7, exhibiting an inhibitoryPureza:98%Forma y color:Odour SolidTet1 peptide
CAS:Tet1peptide is a neuron-specific ligand for GT1B ganglioside. It can serve as a ligand for the targeted delivery of functionalized polymers.Fórmula:C73H114N20O17Forma y color:SolidPeso molecular:1543.81MS1943
CAS:MS1943 is a orally bioavailable EZH2 selective degrader(IC50 of 120 nM).Fórmula:C42H54N8O3Pureza:95.41% - 95.82%Forma y color:SolidPeso molecular:718.93Ref: TM-T13780
1mg42,00€2mgA consultar5mg88,00€10mg137,00€25mg264,00€50mg464,00€100mg845,00€200mg1.396,00€1mL*10mM (DMSO)127,00€CARM1 degrader-2
PROTAC CARM1 degrader-2 (compound 3e), with a DC50 value of 8.8 nM, is a VHL- and proteasome-dependent degrader of co-activator associatedFórmula:C72H100N12O7SPureza:98%Forma y color:SolidPeso molecular:1277.71PRMT4-IN-2
PRMT4-IN-2 (compound 55) acts as a pan-inhibitor across various protein arginine methyltransferase (PRMT) isoforms, exhibiting inhibitory potencies with IC50Forma y color:Odour SolidSAH-EZH2
CAS:EZH2/EPP inhibitor, Kd 320 nM. Reduces EZH2, H3K27me3; halts MLL-AF9 leukemia growth; drives monocyte-macrophage differentiation.
Fórmula:C155H256N48O40Pureza:98%Forma y color:SolidPeso molecular:3432.05EPZ-025654
CAS:EPZ-025654 is an effective and selective inhibitor of arginine methyltransferase CARM1.Fórmula:C29H33ClN8O3Forma y color:SolidPeso molecular:577.08SARS-CoV-2-IN-87
SARS-CoV-2-IN-87 (compound 138968421) is an effective inhibitor of the SARS-CoV-2 methyltransferases (nsp14 and nsp16).Fórmula:C26H40O6Peso molecular:448.28249MRK-990
MRK-990 is an inhibitor of PRMT that targets both PRMT5 and PRMT9, with IC50 values of 30 nM and 10 nM, respectively.Forma y color:Odour SolidEEDi-5285
CAS:EEDi-5285: potent EED inhibitor, orally active, IC50=0.2nM, targets EED protein, anti-cancer properties.
Fórmula:C24H22FN5O3SPureza:100%Forma y color:SolidPeso molecular:479.53DNMT2-IN-2
DNMT2-IN-2 is a selective inhibitor of DNA methyltransferase 2 (DNMT2) with a KD value of 3.04 μM. It targets a concealed allosteric binding site of DNMT2 and reduces m5C levels in tRNA of MOLM-13 cells. This compound works synergistically with Doxorubicin to impair cell viability and is applicable in cancer research, including studies of cervical cancer and leukemia.Forma y color:Odour SolidNSC 370284
CAS:NSC 370284 inhibits STAT3/5, reducing AML cell viability with TET1 overexpression in vitro/in vivo.Fórmula:C21H25NO6Pureza:99.74%Forma y color:SolidPeso molecular:387.43PRMT1-IN-1
CAS:PRMT1-IN-1 is a PRMT1 inhibitor.
Fórmula:C20H7Br6NO5Forma y color:SolidPeso molecular:820.702CM112
CM112 is a selective degrader of protein arginine methyltransferase 1 (PRMT1), which connects a hydrophobic adamantane tag to MS023 via a 5-PEG linker. It induces the degradation of PRMT1 in various solid tumor cell lines. CM112 also targets the non-enzymatic functions of PRMT1 by reducing the stability of the orphan receptor TR3. This compound shows potential for cancer research.Fórmula:C39H61N5O7Forma y color:SolidPeso molecular:711.4571AS-254s
AS-254s is an inhibitor of absent, small, or homeotic-like 1 protein (ASH1L), with an IC50 of 94 nM (FP assay). It exhibits antiproliferative activity against leukemia cells with MLL1 rearrangement, with a GI50 of less than 1 μM. Additionally, AS-254s can induce differentiation in MLL1-r leukemia cells.Fórmula:C36H41ClN6O3S2Forma y color:SolidPeso molecular:705.332UNC 0631
CAS:UNC 0631 is a effectvie histone methyltransferase G9a inhibitor (IC50=4 nM).Fórmula:C37H61N7O2Pureza:97.42%Forma y color:SolidPeso molecular:635.93WDR5-MYC-IN-1
WDR5-MYC-IN-1 (compound 4o) is an effective inhibitor of the WDR5-MYC interaction, demonstrating a Ki value of 1.0 µM and exhibiting antiproliferative activity.Forma y color:Odour SolidCMP-5 2HCl
CAS:CMP-5 2HCl is a anthelmintic agent. CMP-5 2HCl shows EC100 of 5μM against H. contortus in vitro.Fórmula:C21H23Cl2N3Pureza:99.41%Forma y color:SoildPeso molecular:388.33Ref: TM-T10850L
1mg115,00€5mg255,00€10mg375,00€25mg562,00€50mg787,00€100mg1.074,00€1mL*10mM (DMSO)273,00€GSK3735967
CAS:GSK3735967: DNMT1 inhibitor, IC50 40 nM, dicyanopyridine core, binds hemimethylated CpG, interacts with H4K20me3.Fórmula:C25H31N7OSForma y color:SolidPeso molecular:477.62MS115
MS115 is a selective PRMT5/MEP50 PROTAC degrader with DC50 values of 17.4 nM for PRMT5 and 11.3 nM for PRMT5 in MDAMB468 cells after 24 hours. MS115 also inhibits the proliferation of breast cancer cells.Forma y color:Odour SolidBAY-6035
CAS:BAY-6035 is an inhibitor of SET and MYND domain-containing protein 3 (SMYD3). BAY-6035 has more than 100-fold selectivity over other histone methyltransferases.Fórmula:C22H28N4O3Pureza:99.97%Forma y color:SolidPeso molecular:396.48OTS186935 FA
OTS186935 FA is a protein methyltransferase SUV39H2 inhibitor.OTS186935 FA inhibits tumor growth in MDA-MB-231 breast cancer cells.Fórmula:C26H28ClN5O4Pureza:99.52%Forma y color:SoildPeso molecular:509.98Ref: TM-T12344L1
1mg92,00€5mg222,00€10mg371,00€25mg673,00€50mg1.044,00€100mg1.459,00€500mg2.907,00€1mL*10mM (DMSO)255,00€MRTX9768 hydrochloride
MRTX9768 hydrochloride is a potent, orally active PRMT5 inhibitor.Forma y color:SolidPARP/EZH2-IN-1
CAS:PARP/EZH2-IN-1: Dual PARP (IC50 6.87 nM) & EZH2 (IC50 36.51 nM) inhibitor, potential for BRCA-wild-type triple-negative breast cancer.Fórmula:C43H41FN8O5Forma y color:SolidPeso molecular:768.85LLY-284
CAS:LLY-284, a less active PRMT5 inhibitor diastereomer of LLY-283, serves as its negative control.Fórmula:C17H18N4O4Pureza:98%Forma y color:SolidPeso molecular:342.35UNC7096
UNC7096 is a potent, selective degrader of NSD2-PWWP1, exhibiting a dissociation constant (Kd) of 46 nM, and shows promise for treating NSD2-related diseases [1Fórmula:C61H87N7O18SPureza:98%Forma y color:SolidPeso molecular:1238.44METTL16-IN-1
METTL16-IN-1 is a potent inhibitor of METTL16, with an IC50 value of 1.7 μM and a Kd value of 1.35 μM. It effectively suppresses the binding of U6 snRNA deletion to the METTL16 MTD, with an IC50 value of 2.5 μM. METTL16-IN-1 also exhibits antitumor activity.Fórmula:C19H12BrN3O6S2Peso molecular:520.93509DDO-2093
CAS:DDO-2093 inhibits MLL1-WDR5 interaction (IC50: 8.6 nM, Kd: 11.6 nM), with strong antitumor properties and selectivity.Fórmula:C29H37ClFN9O3Forma y color:SolidPeso molecular:614.12GSK 591 dihydrochloride
CAS:Strong PRMT5 inhibitor with 4 nM IC50, surpassing other PRMTs; halts MCL growth in lab tests.Fórmula:C22H30Cl2N4O2Forma y color:SolidPeso molecular:453.41UNC-4219 TFA
CAS:UNC4219 is a control for UNC3866, blocking Kme reader function in CBX & CDY chromodomains.Fórmula:C46H69F3N6O10Pureza:98%Forma y color:SolidPeso molecular:923.085Gintemetostat
CAS:Gintemetostat (KTX-1001) is a potent NSD2 inhibitor (IC50=0.001-0.01μM) for treating NSD2-dysregulated cancers.Fórmula:C25H26F4N8O2Forma y color:SolidPeso molecular:546.522'-Deoxy-2'-fluoro-β-D-arabinocytidine hydrochloride
CAS:2'-Deoxy-2'-fluoro-beta-D-arabinocytidine HCl inhibits DNA methyltransferase with potential anti-tumor properties.Fórmula:C9H13ClFN3O4Pureza:99.43%Forma y color:SolidPeso molecular:281.67AMI-1 free acid
CAS:AMI-1: Potent reversible PRMT inhibitor; IC50: 8.8 μM (hPRMT1), 3.0 μM (yeast-Hmt1p); blocks substrate binding.
Fórmula:C21H16N2O9S2Pureza:97.8%Forma y color:SolidPeso molecular:504.49PROTAC EZH2 Degrader-1
CAS:PROTAC EZH2 Degrader-1 suppresses EZH2 methyltransferase activity with IC50 2.7 nM, serving as a potent tool in cancer research and EZH2 inhibition studies.Fórmula:C54H67N7O8Forma y color:SolidPeso molecular:942.15MS8511 hydrochloride
CAS:MS8511 hydrochloride is a selective G9a/GLP inhibitor with IC50 values of 100 nM and 140 nM respectively, exhibiting covalent and irreversible characteristics.
Fórmula:C28H42ClN5O3Forma y color:SolidPeso molecular:532.12O6BTG-octylglucoside
CAS:O6BTG-octylglucoside is a potent O6-methylguanine-DNAmethyl-transferase (MGMT) inhibitor (IC50s: 10 nM and 32 nM in HeLa S3 cells and in vitro (cell extracts)).Fórmula:C24H34BrN5O7SPureza:98%Forma y color:SolidPeso molecular:616.53(R)-GSK-3685032
CAS:(R)-GSK-3685032 is a selective, reversible DNMT1 inhibitor, non-covalent, IC50: 0.036 μM; reduces DNA methylation, inhibits cancer growth.Fórmula:C22H24N6OSForma y color:SolidPeso molecular:420.545-Aza-2'-deoxycytidine
CAS:Fórmula:C8H12N4O4Pureza:>98.0%(HPLC)Forma y color:White to Almost white powder to crystalPeso molecular:228.21O6-Benzylguanine
CAS:Fórmula:C12H11N5OPureza:>98.0%(T)(HPLC)Forma y color:White to Light yellow powder to crystalPeso molecular:241.25EZM0414 TFA
CAS:EZM0414 TFA (SETD2-IN-1 TFA) is a SETD2 inhibitor with anticancer and antiproliferative effects for the study of leukemia and immune dysfunction.Fórmula:C24H30F4N4O4Pureza:98.88%Forma y color:SolidPeso molecular:514.51DA-3003-1
CAS:DA-3003-1 (NSC 663284) is a Cdc25 dual specificity phosphatase inhibitor with antitumor activity and inhibits Cdc25B2, Cdc25A, Cdc25B2, and Cdc25C.Fórmula:C15H16ClN3O3Pureza:99.27% - 99.79%Forma y color:SolidPeso molecular:321.76EHMT2-IN-1
CAS:EHMT2-IN-1: potent EHMT inhibitor, for blood disorders/cancer research; IC50s <100 nM for EHMT1/2 peptides and cellular EHMT2.Fórmula:C18H23N7OForma y color:SolidPeso molecular:353.42(R)-HH2853
CAS:(R)-HH2853, a mutant EZH2 inhibitor, IC50 <100 nM for EZH2-Y641F, targets cancer/autoimmune diseases.Fórmula:C31H36F3N7O3Pureza:97.53% - 98.85%Forma y color:SolidPeso molecular:611.665'-Azido-5'-deoxyadenosine
CAS:5'-Azido-5'-deoxyadenosine is a purine nucleoside analogue, inhibit Trichomonas vaginalis and PRMT5 , click chemistry alkyne, DBCO, or BCN groups.Fórmula:C10H12N8O3Pureza:99.84%Forma y color:SolidPeso molecular:292.25PR5-LL-CM01
CAS:PR5-LL-CM01 is a novel protein arginine methyltransferase 5 (PRMT5) inhibitor in colorectal and pancreatic cancers.Fórmula:C23H27N7Forma y color:SolidPeso molecular:401.51EPZ020411
CAS:EPZ020411 is a specific and effective inhibitor of PRMT6 (IC50=10 nM).Fórmula:C25H38N4O3Forma y color:SolidPeso molecular:442.6AZ505 ditrifluoroacetate
CAS:AZ505 ditrifluoroacetate is an effective and selective SMYD2 inhibitor (IC50: 0.12 μM).Fórmula:C33H40Cl2F6N4O8Forma y color:SolidPeso molecular:805.59AS-85
CAS:AS-85 is an ASH1L inhibitor with anti-leukemic activity that inhibits leukemic cell growth and increases cLogP.Fórmula:C26H28F3N5O3S2Pureza:98.96%Forma y color:SolidPeso molecular:579.66MRTX9768
CAS:MRTX-9768 is a synthetic lethal-based inhibitor designed to bind the PRMT5-MTA complex and selectively target MTAP/CDKN2A-deleted tumors.Fórmula:C24H17FN6OPureza:97.02%Forma y color:SolidPeso molecular:424.43Pinometostat
CAS:Pinometostat (EPZ-5676) is a potent DOT1L histone methyltransferase inhibitor. Pinometostat has antitumor activity. Cost effective and quality assured.Fórmula:C30H42N8O3Pureza:99.19% - 99.86%Forma y color:SolidPeso molecular:562.71TP-064
CAS:TP-064: Potent, selective PRMT4 inhibitor, IC50 < 10nM for H3 methylation, 100x selectivity, blocks MED12 methylation at 43nM.Fórmula:C28H34N4O2Pureza:97.85%Forma y color:SolidPeso molecular:458.6Ref: TM-T28996
1mg38,00€2mg49,00€5mg79,00€10mg119,00€25mg245,00€50mg487,00€100mg710,00€1mL*10mM (DMSO)80,00€SGC2085 HCl
CAS:SGC2085: potent, selective CARM1 inhibitor; IC50=50 nM; >100x selectivity vs other PRMTs; impacts cancer growth.Fórmula:C19H24N2O2·HClPureza:99.91%Forma y color:SolidPeso molecular:348.87Ref: TM-T4013
1mg93,00€2mg150,00€5mg190,00€10mg343,00€25mg567,00€50mg825,00€100mg1.130,00€1mL*10mM (DMSO)244,00€OICR-9429
CAS:OICR-9429 blocks WDR5 binding to MLL/Histone 3, hindering acute myeloid leukemia cell growth in vitro.
Fórmula:C29H32F3N5O3Pureza:97.07% - 99.93%Forma y color:SolidPeso molecular:555.59Tazemetostat
CAS:Tazemetostat (EPZ6438): Oral EZH2 inhibitor, blocks histone H3K27 methylation, potential cancer therapy.Fórmula:C34H44N4O4Pureza:98.24% - ≥95%Forma y color:SolidPeso molecular:572.74Ref: TM-T1788
2mg35,00€5mg52,00€10mg73,00€25mg92,00€50mg92,00€100mg153,00€500mg383,00€1mL*10mM (DMSO)66,00€AMI-1
CAS:AMI-1 is an effective and selective Histone Methyltransferase (HMT) inhibitor (IC50: 3.0/8.8 μM, for yeast Hmt1p, and human PRMT1).
Fórmula:C21H14N2Na2O9S2Pureza:97.53% - 99.9%Forma y color:DrypowderPeso molecular:548.45GSK591
CAS:GSK591 (GSK3203591), Alternative Names are EPZ015866, GSK3203591, is a potent selective inhibitor of the arginine methyltransferase PRMT5 (IC50=11 nM).Fórmula:C22H28N4O2Pureza:99.35% - 99.45%Forma y color:SolidPeso molecular:380.48Ref: TM-T6853
1mg46,00€2mg58,00€5mg95,00€10mg137,00€25mg268,00€50mg404,00€100mg567,00€1mL*10mM (DMSO)101,00€HLCL-61 hydrochloride
CAS:HLCL-61 hydrochloride (HLCL-61 HCL) is a potent and selective PRMT5 inhibitor for the treatment of acute myeloid leukemia.Fórmula:C23H24N2O·ClHPureza:99.88% - 99.95%Forma y color:SolidPeso molecular:380.91BRD9539
CAS:BRD9539 is an inhibitor of euchromatin histone methyltransferase 2 (EHMT2), also known as G9a, with an IC50 value of 6.3 μMFórmula:C24H21N3O3Pureza:98% - 99.57%Forma y color:SolidPeso molecular:399.44SGC707
CAS:SGC707 is a potent, selective, and cell-active allosteric inhibitor of PRMT3.Fórmula:C16H18N4O2Pureza:99.75% - 99.89%Forma y color:SolidPeso molecular:298.34SETDB1-TTD-IN-1
CAS:SETDB1-TTD-IN-1 is a potent and selective inhibitor of SET domain bifurcated protein 1 tandem tudor domain (SETDB1-TTD, Kd = 88 nM).Cost-effective and quality-assured.Fórmula:C28H31N5O2Pureza:98.26% - 99.96%Forma y color:SolidPeso molecular:469.58LLY-507
CAS:LLY-507 is an effective, cell-active, and specific inhibitor of protein-lysine Methyltransferase SMYD2.Fórmula:C36H42N6OPureza:99.58% - 99.93%Forma y color:SolidPeso molecular:574.76Ref: TM-T6879
1mg44,00€2mg55,00€5mg85,00€10mg138,00€25mg304,00€50mg552,00€100mg787,00€1mL*10mM (DMSO)110,00€Zebularine
CAS:Zebularine (4-Deoxyuridine) is a DNA methylation inhibitor.Fórmula:C9H12N2O5Pureza:99.04% - >99.99%Forma y color:SolidPeso molecular:228.2UNC0642
CAS:UNC0642 is an effective and specific G9a/GLP inhibitor (IC50< 2.5 nM).Fórmula:C29H44F2N6O2Pureza:98.75% - 99.5%Forma y color:SolidPeso molecular:546.7Ref: TM-T4166
1mg38,00€2mg50,00€5mg82,00€10mg124,00€25mg219,00€50mg358,00€100mg537,00€200mg782,00€1mL*10mM (DMSO)89,00€MS049
CAS:MS 049 is a potent, selective, and cell-active dual inhibitor of PRMT4 and PRMT6 with IC 50 of 34 nM and 43 nM, respectively.Fórmula:C15H24N2OPureza:98.91%Forma y color:SolidPeso molecular:248.36Ref: TM-T4378
2mg35,00€5mg51,00€10mg85,00€25mg158,00€50mg235,00€100mg354,00€200mg520,00€1mL*10mM (DMSO)55,00€EED226
CAS:EED226 is a potent, selective, and orally bioavailable embryonic ectoderm development (EED) inhibitor with an IC50 of 22 nM.Fórmula:C17H15N5O3SPureza:98.14% - 99.33%Forma y color:SolidPeso molecular:369.4Succinic acid sodium
CAS:Succinic acid sodium is an orally active anxiolytic.Fórmula:C4H6O4·xNaForma y color:Solidγ-Oryzanol
CAS:γ-Oryzanol (Gamma-Oryzanol) is a natural nutrient extract isolated from rice bran oil that contains a mixture of sterols and ferulic acids, which may aid in theFórmula:C40H58O4Pureza:mixture - mixtureForma y color:White Or White Crystalline Powder OdourlessPeso molecular:602.93-deazaneplanocin A HCl
CAS:3-deazaneplanocin A HCl is both an S-adenosyl-l-homocysteine hydrolase inhibitor and an enhancer of zeste homolog 2(EZH2) inhibitor.Fórmula:C12H15ClN4O3Pureza:93.24% - 98.9%Forma y color:SolidPeso molecular:298.73OTS186935 hydrochloride
OTS186935 HCl inhibits SUV39H2 (IC50 6.49 nM), curbs tumor growth in mice, and modulates γ-H2AX in cancer cells.Fórmula:C25H27Cl2N5O2Forma y color:SolidPeso molecular:522.31Gambogenic acid
CAS:Gambogenic acid is a natural product,is an effective inhibitor of EZH2,with anticancer activity.Fórmula:C38H46O8Pureza:97.47% - 99.6%Forma y color:SolidPeso molecular:630.77Ref: TM-T8201
1mg47,00€5mg92,00€10mg152,00€25mg268,00€50mg429,00€100mg685,00€200mg888,00€1mL*10mM (DMSO)128,00€AZ505
CAS:AZ505 is an effective and specific SMYD2 inhibitor (IC50: 0.12 μM).Fórmula:C29H38Cl2N4O4Pureza:98.18%Forma y color:SolidPeso molecular:577.54Ref: TM-TQ0100
1mg60,00€5mg130,00€10mg178,00€25mg295,00€50mg462,00€100mg623,00€1mL*10mM (DMSO)165,00€Tazemetostat hydrobromide
CAS:Tazemetostat hydrobromide: potent, selective EZH2 inhibitor; blocks PRC2/wild-type EZH2 (Ki: 2.5 nM) & EZH1 (IC50: 392 nM).Fórmula:C34H45BrN4O4Pureza:99.8%Forma y color:SolidPeso molecular:653.65Ref: TM-T17002
2mg43,00€5mg60,00€10mg81,00€50mg96,00€100mg159,00€200mg230,00€500mg378,00€1mL*10mM (DMSO)84,00€SGC0946
CAS:SGC0946 is a highly effective and specific DOT1L methyltransferase inhibitor (IC50: 0.3 nM); selectively kill mixed lineage leukemia cells.Fórmula:C28H40BrN7O4Pureza:98% - 99.82%Forma y color:SolidPeso molecular:618.57BIX-01294
CAS:BIX-01294 is an G9a Histone Methyltransferase inhibitor(IC50 : 1.9 μM).Fórmula:C28H38N6O2Pureza:98.58% - 99.64%Forma y color:SolidPeso molecular:490.64Ref: TM-T7697
1mg38,00€5mg80,00€10mg111,00€25mg197,00€50mg295,00€100mg447,00€200mg607,00€1mL*10mM (DMSO)124,00€UNC1215
CAS:UNC1215, a potent MBT antagonist, targets L3MBTL3 with high selectivity (IC50: 40 nM, Kd: 120 nM, 50x versus MBT family).Fórmula:C32H43N5O2Pureza:98% - 99.04%Forma y color:SolidPeso molecular:529.72C-7280948
CAS:C-7280948 is a PRMT1 inhibitor.Fórmula:C14H16N2O2SPureza:99.55% - ≥95%Forma y color:SolidPeso molecular:276.35Ref: TM-T2097
5mg46,00€10mg66,00€25mg109,00€50mg178,00€100mg268,00€200mg414,00€500mg667,00€1mL*10mM (DMSO)49,00€WDR5-0103
CAS:WDR5-0103 (WD-Repeat Protein 5-0103) is an effective and specific WD repeat-containing protein 5 (WDR5) antagonist (Kd: 450 nM).Fórmula:C21H25N3O4Pureza:98% - 99.61%Forma y color:SolidPeso molecular:383.44CM-579 trihydrochloride
CM-579 trihydrochloride: reversible G9a/DNMT inhibitor with IC50s 16 nM (G9a) & 32 nM (DNMT); potent against various cancer cells.Fórmula:C29H43Cl3N4O3Forma y color:SolidPeso molecular:602.04Piribedil
CAS:Piribedil (Trivastan) is a dopamine D2 agonist, used in the treatment of Parkinson's disease.Fórmula:C16H18N4O2Pureza:99.79% - 99.82%Forma y color:SolidPeso molecular:298.34A-196
CAS:A-196 is a potent and selective inhibitor of SUV420 h1 and SUV420 h2 with IC50 values of 0.025 and 0.144 μM, respectively; more than 100-fold selective overFórmula:C18H16Cl2N4Pureza:99.92%Forma y color:SolidPeso molecular:359.25
