ADN metiltransferasa
Las metiltransferasas de ADN (DNMT) son enzimas que catalizan la adición de grupos metilo a los residuos de citosina en el ADN, lo que lleva al silenciamiento génico. La metilación aberrante del ADN está asociada con diversas enfermedades, incluido el cáncer. Los inhibidores de DNMT bloquean la actividad de estas enzimas, lo que lleva a la reactivación de genes silenciados y la inducción de apoptosis en células cancerosas. Los inhibidores de DNMT se utilizan ampliamente en la investigación epigenética y la terapia contra el cáncer. En CymitQuimica, ofrecemos una gama de inhibidores de DNMT de alta calidad para apoyar su investigación en epigenética, metilación del ADN y biología del cáncer.
Se han encontrado 422 productos de "ADN metiltransferasa"
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UNC6934
CAS:<p>UNC6934 is a chemical probe targeting the N-terminal PWWP (PWWP1) domain of NSD2.</p>Fórmula:C24H21N5O4Pureza:98.67%Forma y color:SolidPeso molecular:443.45Amodiaquine hydrochloride
CAS:<p>Amodiaquine dihydrochloride: 4-aminoquinoline antimalarial, histamine N-methyltransferase inhibitor (Ki 18.6 nM), Nurr1 agonist, anti-inflammatory.</p>Fórmula:C20H24Cl3N3OForma y color:SolidPeso molecular:428.78UNC3866
CAS:<p>UNC3866 is a potent antagonist of the CBX7-H3 interaction as determined by AlphaScreen.</p>Fórmula:C43H66N6O8Pureza:88.06% - 99.62%Forma y color:SolidPeso molecular:795.02UNC0642
CAS:<p>UNC0642 is an effective and specific G9a/GLP inhibitor (IC50< 2.5 nM).</p>Fórmula:C29H44F2N6O2Pureza:98.75% - 99.5%Forma y color:SolidPeso molecular:546.7MR837
CAS:<p>MR837 (NSD2-PWWP1 antagonist 3f) is a NSD2-PWWP1 antagonist.</p>Fórmula:C16H14N2OSPureza:99.77% - 99.85%Forma y color:SolidPeso molecular:282.36Hinokitiol
CAS:<p>Hinokitiol prevents UVB-caused cell death, boosts antioxidant activity, and hinders breast cancer growth.</p>Fórmula:C10H12O2Pureza:99.49% - 99.67%Forma y color:SolidPeso molecular:164.2UNC0379
CAS:<p>UNC0379 is a selective, substrate-competitive inhibitor of the lysine methyltransferase SETD8.</p>Fórmula:C23H35N5O2Pureza:94.41% - 99.97%Forma y color:SolidPeso molecular:413.56MS023
CAS:<p>MS023 is a potent, selective, and cell-active Type I PRMT inhibitor with IC50 of 30 nM, 119 nM, 83 nM, 4 nM, and 5 nM for PRMT1, PRMT3, PRMT4, PRMT6 and PRMT8,</p>Fórmula:C17H25N3OPureza:98.31% - 99.87%Forma y color:SolidPeso molecular:287.45-Fluoro-2'-deoxycytidine
CAS:<p>5-Fluoro-2'-deoxycytidine (2'-DEOXY-5-FLUOROCYTIDINE) is an inhibitor of DNA methyltransferase (DNMT) .</p>Fórmula:C9H12FN3O4Pureza:97.91%Forma y color:Fine White PowderPeso molecular:245.21SGC2085
CAS:<p>SGC2085 is an effective and selective coactivator-associated arginine methyltransferase 1 (CARM1) inhibitor (IC50: 50 nM).</p>Fórmula:C19H24N2O2Pureza:99.61% - 99.71%Forma y color:SolidPeso molecular:312.41Bobcat339
CAS:<p>Bobcat339 is a novel cytosine-based TET enzyme inhibitor (IC50s: 33/73 uM for TET1/2), but not DNMT3a, does not inhibit the DNA methyltransferase DNMT3a.</p>Fórmula:C16H12ClN3OPureza:97.79% - 99.24%Forma y color:SolidPeso molecular:297.74EPZ004777 hydrochloride
CAS:<p>EPZ004777 hydrochloride (EPZ004777 HCl) is a potent, selective DOT1L inhibitor with IC50 of 0.4 nM.</p>Fórmula:C28H42ClN7O4Forma y color:SolidPeso molecular:576.13MRTX-1719
CAS:<p>MRTX-1719 is a potent and selective inhibitor of the PRMT5/MTA complex with an IC50 value of <10 nM against PRMT5/MTAMTAPDELSDMA cell lines.Cost-effective and quality-assured.</p>Fórmula:C23H18ClFN6O2Pureza:98.27% - 99.18%Forma y color:SolidPeso molecular:464.88MS37452
CAS:<p>MS37452 is a competitive inhibitor of CBX7 chromodomain binding to H3K27me3 (Ki = 43 µM).</p>Fórmula:C22H26N2O5Pureza:99.39%Forma y color:SolidPeso molecular:398.45DCLX069
CAS:<p>DCLX069: PRMT1 inhibitor, IC50=17.9µM, targets SAM pocket, inhibits breast/liver cancer, and AML cell growth.</p>Fórmula:C20H25N3O2Pureza:97.76%Forma y color:SolidPeso molecular:339.43GSK503
CAS:<p>GSK-503, a potent EZH2 inhibitor, has potential antitumor activity.</p>Fórmula:C31H38N6O2Pureza:98% - 99.89%Forma y color:SolidPeso molecular:526.67EPZ011989
CAS:<p>EPZ011989: potent, selective oral EZH2 inhibitor, Ki < 3 nM, 15x more selective than EZH1, >3000x over other HMTases.</p>Fórmula:C35H51N5O4Pureza:98% - 99.45%Forma y color:SolidPeso molecular:605.81GSK343
CAS:<p>GSK343, a specific and effective EZH2 inhibitor (IC50=4 nM), exhibits 60 fold specificity activity against EZH1, and >1000 fold specificity activity against</p>Fórmula:C31H39N7O2Pureza:98% - 99.9%Forma y color:SolidPeso molecular:541.696-Thioguanine
CAS:<p>6-Thioguanine (2-Amino-6-purinethiol) is an antineoplastic compound which also has antimetabolite action. The drug is used in the therapy of acute leukemia.</p>Fórmula:C5H5N5SPureza:98.34% - >99.99%Forma y color:Odorless Or Almost Odorless Pale Yellow Crystalline PowderPeso molecular:167.19γ-Oryzanol
CAS:<p>γ-Oryzanol (Gamma-Oryzanol) is a natural nutrient extract isolated from rice bran oil that contains a mixture of sterols and ferulic acids, which may aid in the</p>Fórmula:C40H58O4Pureza:mixture - mixtureForma y color:White Or White Crystalline Powder OdourlessPeso molecular:602.9
