ADN metiltransferasa
Las metiltransferasas de ADN (DNMT) son enzimas que catalizan la adición de grupos metilo a los residuos de citosina en el ADN, lo que lleva al silenciamiento génico. La metilación aberrante del ADN está asociada con diversas enfermedades, incluido el cáncer. Los inhibidores de DNMT bloquean la actividad de estas enzimas, lo que lleva a la reactivación de genes silenciados y la inducción de apoptosis en células cancerosas. Los inhibidores de DNMT se utilizan ampliamente en la investigación epigenética y la terapia contra el cáncer. En CymitQuimica, ofrecemos una gama de inhibidores de DNMT de alta calidad para apoyar su investigación en epigenética, metilación del ADN y biología del cáncer.
Se han encontrado 421 productos de "ADN metiltransferasa"
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MS023 dihydrochloride
CAS:<p>MS023 dihydrochloride (MS023 2HCl) is a human type I protein arginine methyltransferase inhibitor with antitumour activity for the study of breast cancer.</p>Fórmula:C17H27Cl2N3OPureza:99.52%Forma y color:SolidPeso molecular:360.32TNG-462
CAS:<p>TNG-462 is a oral, potent and selective PRMT5 inhibitor for the treatment of MTAP-deficient and/or MTA-accumulating cancers (e.g., pancreatic & bladder).</p>Fórmula:C28H36N6O2SPureza:98.7%Forma y color:SolidPeso molecular:520.69BI-9321 trihydrochloride
CAS:<p>BI-9321 trihydrochloride (BI9321 trihydrochloride) is an NSD3-PWWP1 antagonist that downregulates Myc messenger RNA expression.</p>Fórmula:C22H24Cl3FN4Pureza:99.12% - 99.34%Forma y color:SolidPeso molecular:469.81MRK-740
CAS:<p>MRK-740 is a PRDM9 histone methyltransferase inhibitor that inhibits H3K4 methylation.</p>Fórmula:C25H32N6O3Pureza:99.66%Forma y color:SolidPeso molecular:464.56CBHcy
CAS:<p>CBHcy, a dual substrate analog, is a specific BHMT inhibitor that may induce cysteinemia.</p>Fórmula:C9H17NO4SPureza:>99.99% - >99.99%Forma y color:SolidPeso molecular:235.3PFI-2
CAS:<p>PFI-2 is an effective, specific and cell-active lysine methyltransferase SETD7 inhibitor (Ki/IC50: 0.33/2 nM), 1000-fold selectivity over other</p>Fórmula:C23H25F4N3O3SPureza:99.38%Forma y color:SolidPeso molecular:499.52GSK2807 Trifluoroacetate
CAS:<p>GSK2807 Trifluoroacetate is a selective and SAM-competitive inhibitor of SMYD3 (Ki: 14 nM; IC50: 130 nM).</p>Fórmula:C21H33F3N8O7Pureza:99.95%Forma y color:SolidPeso molecular:566.53Tazemetostat trihydrochloride
CAS:<p>Tazemetostat trihydrochloride, an EZH2 inhibitor, orally active, IC50: 4nM (rat), Ki: 2.5nM (human), effective in peptide and nucleosome assays.</p>Fórmula:C34H47Cl3N4O4Pureza:98%Forma y color:SolidPeso molecular:682.12Acedapsone
CAS:<p>Acedapsone has antimalarial and antimicrobial action, but is mainly used as a depot leprostatic agent.</p>Fórmula:C16H16N2O4SPureza:98%Forma y color:SolidPeso molecular:332.37GSK-1268997
CAS:<p>GSK-1268997 is a bio-active chemical.</p>Fórmula:C21H23N7O3SPureza:99.33% - 99.81%Forma y color:SolidPeso molecular:453.52UNC0224
CAS:<p>UNC0224 is a selective inhibitor of G9a with a Ki of 2.6 nM and IC50 of 15 nM. UNC0224 also potently inhibits GLP with assay-dependent IC50 values of 20-58 nM.</p>Fórmula:C26H43N7O2Pureza:99.80%Forma y color:SolidPeso molecular:485.67MY-1B
CAS:<p>MY-1B is a nitrogen-substituted butenamide stereoprobe that blocks stereoselective enrichment of NSUN2, binding selectively to the C271 of NSUN2.</p>Fórmula:C22H18BrN3O2Pureza:99.81% - >99.99%Forma y color:SoildPeso molecular:436.3PRMT5-IN-2
CAS:<p>PRMT5-IN-2 is an inhibitor of protein arginine methyltransferase 5.</p>Fórmula:C17H16ClFN4O4Pureza:98%Forma y color:SolidPeso molecular:394.78DC_C66
CAS:<p>DC_C66 selectively inhibits CARM1 with IC50 of 1.8μM; also affects PRMT1, 6, 5. It's cell-permeable.</p>Fórmula:C28H22NO2Pureza:98%Forma y color:SolidPeso molecular:404.48PRMT5-IN-17
CAS:<p>PRMT5-IN-17 is a PRMT5-blocking compound with anticancer properties, linked to epigenetic changes.</p>Fórmula:C26H33N7O2Forma y color:SolidPeso molecular:475.59GSK926
CAS:<p>GSK926 is a selective, SAM-competitive, and cell-active EZH2 inhibitor.</p>Fórmula:C29H35N7O2Forma y color:SolidPeso molecular:513.63Arazine
CAS:<p>Arazine, a cell-permeable G protein modulator, is an isoprenylcysteine methyltransferase substrate.</p>Fórmula:C20H33NO3SPureza:90%Forma y color:SolidPeso molecular:367.552′-Deoxy-5-nitrocytidine
CAS:<p>2′-Deoxy-5-nitrocytidine is a DNA Methyltransferase inhibitor that can be used for cancer research[1].</p>Fórmula:C9H12N4O6Forma y color:SolidPeso molecular:272.21DM-01
CAS:<p>DM-01 is a potent and selective inhibitor of EZH2.</p>Fórmula:C23H24F3N3O2Forma y color:SolidPeso molecular:431.45JNJ-7925476 free base
CAS:<p>JNJ-7925476 is an TRI antidepressant agent.</p>Fórmula:C20H19NPureza:98%Forma y color:SolidPeso molecular:273.37
