ADN metiltransferasa
Las metiltransferasas de ADN (DNMT) son enzimas que catalizan la adición de grupos metilo a los residuos de citosina en el ADN, lo que lleva al silenciamiento génico. La metilación aberrante del ADN está asociada con diversas enfermedades, incluido el cáncer. Los inhibidores de DNMT bloquean la actividad de estas enzimas, lo que lleva a la reactivación de genes silenciados y la inducción de apoptosis en células cancerosas. Los inhibidores de DNMT se utilizan ampliamente en la investigación epigenética y la terapia contra el cáncer. En CymitQuimica, ofrecemos una gama de inhibidores de DNMT de alta calidad para apoyar su investigación en epigenética, metilación del ADN y biología del cáncer.
Se han encontrado 421 productos de "ADN metiltransferasa"
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JS1310
CAS:<p>JS1310 is a selective PRMT7 inhibitor (IC50: 5 μM against human PRMT7). JS1310 has shown anti-cancer effects on different cancer cells.</p>Fórmula:C23H22FN5O3Forma y color:SolidPeso molecular:435.45PDAT
CAS:<p>PDAT is a noncompetitive Indolethylamine N-methyltransferase inhibitor.</p>Fórmula:C15H23N3Pureza:98%Forma y color:SolidPeso molecular:245.36Guadecitabine
CAS:<p>Guadecitabine is a second-generation DNA methyltransferases inhibitor. It is used for research on acute myeloid leukemia and myelodysplastic syndromes.</p>Fórmula:C18H24N9O10PPureza:98%Forma y color:SolidPeso molecular:557.41SKF 91488 dihydrochloride
CAS:<p>histamine N-methyltransferase inhibitor</p>Fórmula:C7H19Cl2N3SPureza:98%Forma y color:SolidPeso molecular:248.22RM65
CAS:<p>RM65 is an arginine methyltransferase inhibitor.</p>Fórmula:C34H32N2O4S2Pureza:98%Forma y color:SolidPeso molecular:596.76Lobelane Hydrochloride
CAS:<p>Lobelane Hydrochloride is a vesicular monoamine transporter-2 (VMAT2) inhibitor.</p>Fórmula:C22H30ClNForma y color:SolidPeso molecular:343.93Fagaronine chloride
CAS:<p>Fagaronine chloride is a potent inhibitor of Topoisomerases I.</p>Fórmula:C21H20ClNO4Forma y color:SolidPeso molecular:385.84DC_501
CAS:<p>DC_501 is a selective non-nucleoside DNA methyltransferase 1 inhibitor.</p>Fórmula:C25H23Cl2N3OPureza:98%Forma y color:SolidPeso molecular:452.38Prospasmine
CAS:<p>Prospasmine is an anticholinergic.</p>Fórmula:C17H28ClNO2Pureza:98%Forma y color:SolidPeso molecular:313.87Setin-1
CAS:<p>Setin-1 is the most potent Set7 inhibitor that acts by inhibiting the KMTase G9a.</p>Fórmula:C29H21F3N2O2Pureza:98%Forma y color:SolidPeso molecular:486.48WDR5-0102
CAS:<p>WDR5-0102 inhibits WDR5-MLL1 (Kd=4 μM), blocks MLL1 HMT activity, but doesn't affect SETD7 and 6 other HMTs.</p>Fórmula:C18H19ClN4O3Pureza:98.03%Forma y color:SolidPeso molecular:374.82Cedazuridine
CAS:<p>Cedazuridine ((4R)-2'-Deoxy-2',2'-difluoro-3,4,5,6-tetrahydrouridine) is an oral inhibitor of cytidine deaminase with antineoplastic properties.</p>Fórmula:C9H14F2N2O5Pureza:99.66%Forma y color:SolidPeso molecular:268.21Bobcat339 hydrochloride
CAS:<p>Bobcat339 hydrochloride is a 10 11 translocation (TET) dioxygenase inhibitor that inhibits both TET1 and TET2.</p>Fórmula:C16H13Cl2N3OPureza:99.22%Forma y color:SolidPeso molecular:334.2CPUY074020
CAS:<p>CPUY074020 is a potent and orally bioavailable inhibitor of histone methyltransferase G9a (IC50: 2.18 μM) with anti-proliferative activity.</p>Fórmula:C25H28N4O2Pureza:98.64%Forma y color:SolidPeso molecular:416.52DW14800
CAS:<p>DW14800 is an inhibitor of PRMT5 (IC50 = 17 nM), enhances the transcription of HNF4α, and reduces the level of H4R3me2s.</p>Fórmula:C31H36N4O3Pureza:99.55% - 99.68%Forma y color:SolidPeso molecular:512.64CARM1-IN-1
CAS:<p>CARM1-IN-1 (CARM1-IN-7G) is a selective inhibitor of CARM1 with IC50 of 8.6 μM. CARM1-IN-1 shows weak activity against PRMT1 and SET7 with IC50 > 600 μM.</p>Fórmula:C26H21Br2NO3Pureza:98.24%Forma y color:SolidPeso molecular:555.26TNG908
CAS:<p>TNG908, a brain-penetrant PRMT5 inhibitor, is 15x more selective for MTAP mutant vs WT lines, useful in cancer studies.</p>Fórmula:C21H23N5O2SPureza:98.08% - 98.24%Forma y color:SolidPeso molecular:409.51EZH2-IN-13
CAS:<p>EZH2-IN-13 is a potent EZH2 inhibitor with potential anticancer activity.EZH2-IN-13 may be used to study diseases associated with EZH2 activity.</p>Fórmula:C34H45N5O3Pureza:98.3%Forma y color:SolidPeso molecular:571.75Procainamide
CAS:<p>Procainamide: DNMT1 inhibitor, Class 1A antiarrhythmic, promising for cancer and arrhythmia research.</p>Fórmula:C13H21N3OPureza:99.92% - 99.92%Forma y color:SolidPeso molecular:235.33TM2-115
CAS:<p>TM2-115 is a inhibitor of malaria parasite histone methyltransferases that results in rapid and irreversible parasite death [1].</p>Fórmula:C28H38N6O2Pureza:97.67%Forma y color:SolidPeso molecular:490.64
