Antimetabolito / análogo nucleósido
Los antimetabolitos y análogos de nucleósidos son compuestos que imitan a los nucleósidos naturales y se incorporan al ADN durante la replicación, lo que provoca la terminación de la cadena o la inhibición de la síntesis de ADN. Estos compuestos se utilizan ampliamente como agentes quimioterapéuticos en el tratamiento del cáncer y las infecciones virales. Al interrumpir la síntesis de ADN, los análogos de nucleósidos inducen el arresto del ciclo celular y la apoptosis. En CymitQuimica, ofrecemos una amplia gama de antimetabolitos y análogos de nucleósidos de alta calidad para apoyar su investigación en el tratamiento del cáncer, la terapia antiviral y la replicación del ADN.
Se han encontrado 1422 productos de "Antimetabolito / análogo nucleósido"
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N1-Methylpseudouridine
CAS:N1-Methylpseudouridine (1-Methylpseudouridine) is a methylpseudouridine and enhances translation through eIF2α-dependent and independent mechanisms byFórmula:C10H14N2O6Pureza:98.95% - 99.88%Forma y color:SolidPeso molecular:258.23Ara-G
CAS:<p>Ara-G, a deoxyguanosine analog, inhibits DNA synthesis, targeting T cell leukemia by converting to araGTP.</p>Fórmula:C10H13N5O5Pureza:98.74%Forma y color:Slightly Off White To White PowderPeso molecular:283.24Orotic acid zinc
CAS:Orotic acid zinc (Zinc Orotate) salt dihydrate is an intermediate product in pyrimidine synthesis.Fórmula:C10H6N4O8ZnPureza:99.13%Forma y color:SolidPeso molecular:188.796-Thioinosine
CAS:6-Thioinosine (6TI) is a purine antimetabolite, acts as an anti-adipogenesis agent.Fórmula:C10H12N4O4SPureza:97.74%Forma y color:SolidPeso molecular:284.29Gemcitabine hydrochloride
CAS:Gemcitabine hydrochloride (LY 188011 hydrochloride) is a synthetic cytosine nucleoside derivative and an inhibitor of DNA synthesis.Fórmula:C9H11F2N3O4·HClPureza:99.28% - 99.98%Forma y color:White Crystalline Granular OdorlessPeso molecular:299.66Tiazofurin
CAS:Tiazofurin, a synthetic nucleoside, has anti-cancer effects and inhibits IMPDH as TAD after metabolism.Fórmula:C9H12N2O5SPureza:99.91%Forma y color:SolidPeso molecular:260.27Pseudouridine
CAS:Pseudouridine, prevalent in non-coding RNAs, boosts tRNA and rRNA function by RNA stabilization.Fórmula:C9H12N2O6Pureza:99.3%Forma y color:SolidPeso molecular:244.2Triazavirin
CAS:Triazavirin is a nucleoside analogue of nucleic acid and an antiviral agent.Fórmula:C5H7N6NaO5SPureza:99.55%Forma y color:SolidPeso molecular:286.2Fludarabine Phosphate
CAS:Fludarabine Phosphate (NSC 312887 Phosphate) is a fluorinated nucleotide antimetabolite analog of the antiviral agent vidarabine with antineoplastic activity.Fórmula:C10H13FN5O7PPureza:99.25% - 99.78%Forma y color:SolidPeso molecular:365.21Ref: TM-T6501
5mg38,00€10mg57,00€25mg92,00€50mg115,00€100mg140,00€200mg190,00€500mg319,00€1mL*10mM (DMSO)55,00€2'-Fluoro-2'-Deoxyadenosine
CAS:2'-Fluoro-2'-Deoxyadenosine is efficiently cleaved to the toxic 2-fluoroadenine (FAde) by Escherichia coli purine nucleoside phosphorylase (PNP).Fórmula:C10H12FN5O3Pureza:99.95%Forma y color:SolidPeso molecular:269.23Preq1-Dihydrochloride
CAS:Preq1-Dihydrochloride, a queuosine pathway intermediate, binds strongly to PreQ1 riboswitch aptamer, suppressing protein expression.Fórmula:C7H11Cl2N5OPureza:99.46%Forma y color:SolidPeso molecular:252.1dGTP
CAS:dGTP (2'-Deoxyguanosine-5'-triphosphate) is one of the guanosine nucleotides which is highly susceptible to oxidative damage to 8-O-GDP, 8-O-dGTP, 8-O-GTP, andFórmula:C10H16N5O13P3Pureza:99.64%Forma y color:SolidPeso molecular:507.18Deoxythymidine-5'-triphosphate trisodium
CAS:dTTP trisodium salt, a natural deoxynucleotide for DNA synthesis by DNA polymerase and reverse transcriptase.Fórmula:C10H14N2Na3O14P3Pureza:97.47%Forma y color:SolidPeso molecular:548.11N6,N6-Dimethyladenosine
CAS:<p>N6,N6-Dimethyladenosine is find in mycobacterium bovis Bacille Calmette-Guérin tRNA.</p>Fórmula:C12H17N5O4Pureza:98.79%Forma y color:White PowderPeso molecular:295.298-Azaguanine
CAS:8-Azaguanine (SK 1150) is a purine analogue with potential antineoplastic activity.Fórmula:C4H4N6OPureza:99.26% - >99.99%Forma y color:White To Off-White Crystalline PowderPeso molecular:152.11Trifluridine/tipiracil hydrochloride mixture
CAS:Trifluridine/tipiracil hydrochloride mixture (TAS-102) is a novel oral combination drug containing trifluridine (TFT) and Tipiracil hydrochloride (TTP) in aFórmula:C29H34Cl2F6N8O12Pureza:98% - 99.79%Forma y color:SolidPeso molecular:871.53Ref: TM-T3658
2mg39,00€5mg57,00€10mg87,00€25mg157,00€50mg250,00€100mg378,00€200mg568,00€500mg889,00€1mL*10mM (DMSO)78,00€RX-3117
CAS:RX-3117 (fluorocyclopentenylcytosine) is a novel a cytidine analog.Fórmula:C10H12FN3O4Pureza:97.46%Forma y color:SolidPeso molecular:257.22Ref: TM-T16813
1mg157,00€2mg212,00€5mg309,00€10mg444,00€25mg728,00€50mg1.017,00€100mg1.378,00€1mL*10mM (DMSO)319,00€7-Methylguanosine
CAS:7-Methylguanosine is a novel cNIIIB nucleotidase inhibitor (IC50 : 87.8 ± 7.5 μM).Fórmula:C11H16N5O5Pureza:98.11%Forma y color:SolidPeso molecular:298.286-Mercaptopurine hydrate
CAS:6-Mercaptopurine hydrate is a leukemia treatment; it blocks purine metabolism, affecting DNA synthesis.Fórmula:C5H6N4OSPureza:97.54% - 99.14%Forma y color:Light Yellow Crystalline PowderPeso molecular:170.193'-Deoxyguanosine
CAS:3'-Deoxyguanosine is a ligand that can be complexed with enzymes, such as purine nucleoside phosphorylase, and receptors.Fórmula:C10H13N5O4Pureza:98.85% - 98.96%Forma y color:SolidPeso molecular:267.24
