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Receptor de la hormona tiroidea (THR)

Receptor de la hormona tiroidea (THR)

Los receptores de hormonas tiroideas (THR) son receptores nucleares que median los efectos de las hormonas tiroideas, que son fundamentales para regular el metabolismo, el crecimiento y el desarrollo. La modulación de la actividad de los THR es importante en el tratamiento de trastornos tiroideos, síndromes metabólicos y ciertos tipos de cáncer. Los agonistas y antagonistas de THR se utilizan en la investigación para estudiar los roles fisiológicos y patológicos de las hormonas tiroideas. En CymitQuimica, ofrecemos una amplia gama de moduladores de receptores de hormonas tiroideas de alta calidad para apoyar su investigación en endocrinología, metabolismo y regulación hormonal.

Se han encontrado 44 productos para "Receptor de la hormona tiroidea (THR)".

productos por página.
  • 3,5-Diiodothyropropionic acid

    CAS:
    3,5-Diiodothyropropionic acid: thyroid hormone analog, boosts α-myosin mRNA, binds TRα1 & TRβ1 (Ka: 2.40/M, 4.06/M).
    Fórmula:C15H12I2O4
    Pureza:98.42%
    Forma y color:Solid
    Peso molecular:510.0623
  • PCO371

    CAS:
    PCO371 (2,4-Imidazolidinedione, 1-(3,5-dimethyl-4-(2-((4-oxo-2-(4-(trifluoromethoxy)phenyl)-1,3,8-triazaspiro(4.5)dec-1-en-8-yl)sulfonyl)ethyl)phenyl)-5,5-
    Fórmula:C29H32F3N5O6S
    Pureza:98.00% - 99.25%
    Forma y color:Solid
    Peso molecular:635.654
  • Parathyroid Hormone (1-34), bovine

    CAS:
    Parathyroid Hormone (1-34), bovine is a PTH receptor agonist used to study osteoporosis and hypoparathyroidism.
    Fórmula:C183H288N54O50S2
    Pureza:99.72%
    Forma y color:Solid
    Peso molecular:4104.39
  • pTH (1-37) (human)

    CAS:
    pTH (1-37) human fragment boosts cAMP, alkaline phosphatase, growth, and BMD, potential for osteoporosis research.
    Fórmula:C195H316N58O54S2
    Forma y color:Solid
    Peso molecular:4401.08
  • Eneboparatide

    CAS:
    Eneboparatide (AZP-3601) is a novel peptide agonist of the PTHR1 (parathyroid hormone receptor 1), for hypoparathyroidism, control serum calcium levels.
    Fórmula:C191H312N60O49S
    Peso molecular:4262.34874
  • Human PTH-(1-31) amide

    CAS:
    Human PTH-(1-31) amide, an analog of PTH, effectively stimulates phosphatidylcholine hydrolysis and promotes the release of adenylyl cyclase [1].
    Fórmula:C162H270N50O46S2
    Forma y color:Solid
    Peso molecular:3718.31
  • Osteostatin (1-5) amide (human, bovine, dog, horse, mouse, rabbit, rat)

    CAS:
    Osteostatin (1-5) amide (human, bovine, dog, horse, mouse, rabbit, rat), also known as Human PTHrP (107-111) amide, is a C-terminal fragment of parathyroid
    Fórmula:C27H42N10O7
    Forma y color:Solid
    Peso molecular:618.69
  • Osteostatin

    CAS:
    Osteostatin, derived from parathyroid hormone-related protein (PTHrP) 107-111, has demonstrated properties conducive to bone repair in animal models presenting
    Fórmula:C27H41N9O8
    Forma y color:Solid
    Peso molecular:619.67
  • DPC-AJ1951

    CAS:
    Potent 14 amino acid peptide agonist of the parathyroid hormone (PTH) receptor (EC50 = 26 nM).
    Fórmula:C76H127N23O19
    Pureza:98%
    Forma y color:Solid
    Peso molecular:1666.98
  • NH-3

    CAS:
    NH-3, an orally active THR antagonist with a 55 nM IC50, blocks thyroid hormone binding and cofactor recruitment.
    Fórmula:C28H27NO6
    Pureza:97.79% - 99.45%
    Forma y color:Solid
    Peso molecular:473.5171
  • Prepro-TRH-(160-169)

    CAS:
    Prepro-TRH-(160-169), a pro-TRH peptide, enhances TRH-stimulated TSH secretion.
    Fórmula:C54H75N11O18S
    Forma y color:Solid
    Peso molecular:1198.3
  • THR-β agonist 2 diacetate


    THR-β agonist 2 diacetate (Compound 3) is a potent THR-β agonist with potential applications in researching metabolic disorders such as obesity, hyperlipidemia, hypercholesterolemia, and diabetes, as well as other conditions like steatosis and non-alcoholic steatohepatitis (NASH), atherosclerosis, and other related diseases and conditions.
    Forma y color:Odour Solid
  • Trh-gly

    CAS:
    TRH-glycine (TRH-gly) serves as a precursor to thyrotropin-releasing hormone (TRH), capable of inducing the release of thyrotropin (TSH) and prolactin [1].
    Fórmula:C18H24N6O6
    Forma y color:Solid
    Peso molecular:420.42
  • pTH-Related Protein (1-34) amide (human, mouse, rat)

    CAS:
    Human PTHrP-(1-34)NH2, also known as PTH-Related Protein (1-34) amide for human, mouse, and rat, is the N-terminal fragment of PTHrP.
    Forma y color:Solid
  • (Tyr36)-pTH-Related Protein (1-36) (human, mouse, rat)

    CAS:
    '(Tyr36)-pTH-Related Protein (1-36) (human, mouse, rat), a peptide, functions as a ligand for parathyroid hormone (PTH) receptors [1].'
    Fórmula:C194H303N59O53
    Forma y color:Solid
    Peso molecular:4309.85
  • DPC-AJ1951 TFA


    DPC-AJ1951 TFA is a 14 amino acid peptide, potent PTH/PPR agonist, tested in bone resorption assays.
    Fórmula:C78H128F3N23O21
    Forma y color:Solid
    Peso molecular:1781.02
  • Parathyroid hormone (1-34) (rat)

    CAS:
    Parathyroid hormone (PTH) receptor agonist. Increases serum PTH levels and bone mass in rats.
    Fórmula:C180H291N55O48S2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:4057.74
  • Human PTHrP-(1-36)

    CAS:
    Human PTHrP-(1-36) is a secreted form of parathyroid hormone-related protein that exhibits anticalciuric effects and promotes beta cell function and
    Fórmula:C191H305N59O52
    Forma y color:Solid
    Peso molecular:4259.83
  • Calcitonin, eel

    CAS:
    Calcitonin from eel regulates calcium and is key in studying postmenopausal osteoporosis.
    Fórmula:C146H241N43O47S2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:3414.91
  • THR-β agonist 10


    THR-β agonist 10 is an orally active and selective THR-β agonist with an EC50 value of 11 nM. It effectively lowers levels of ALT (alanine aminotransferase), TC (total cholesterol), and LDL-C (low-density lipoprotein cholesterol). In mouse models of metabolic dysfunction-associated steatohepatitis (MASH), it improves steatosis, ballooning, inflammation, and fibrosis. THR-β agonist 10 is utilized in the research of MASH.