Receptor de la hormona tiroidea (THR)
Los receptores de hormonas tiroideas (THR) son receptores nucleares que median los efectos de las hormonas tiroideas, que son fundamentales para regular el metabolismo, el crecimiento y el desarrollo. La modulación de la actividad de los THR es importante en el tratamiento de trastornos tiroideos, síndromes metabólicos y ciertos tipos de cáncer. Los agonistas y antagonistas de THR se utilizan en la investigación para estudiar los roles fisiológicos y patológicos de las hormonas tiroideas. En CymitQuimica, ofrecemos una amplia gama de moduladores de receptores de hormonas tiroideas de alta calidad para apoyar su investigación en endocrinología, metabolismo y regulación hormonal.
Se han encontrado 32 productos de "Receptor de la hormona tiroidea (THR)"
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3,5-Diiodothyropropionic acid
CAS:3,5-Diiodothyropropionic acid: thyroid hormone analog, boosts α-myosin mRNA, binds TRα1 & TRβ1 (Ka: 2.40/M, 4.06/M).Fórmula:C15H12I2O4Pureza:98.42%Forma y color:SolidPeso molecular:510.06PCO371
CAS:PCO371 (2,4-Imidazolidinedione, 1-(3,5-dimethyl-4-(2-((4-oxo-2-(4-(trifluoromethoxy)phenyl)-1,3,8-triazaspiro(4.5)dec-1-en-8-yl)sulfonyl)ethyl)phenyl)-5,5-Fórmula:C29H32F3N5O6SPureza:97.17% - 99.25%Forma y color:SolidPeso molecular:635.65Ref: TM-T16442
1mg63,00€5mg137,00€10mg197,00€25mg356,00€50mg505,00€100mg715,00€1mL*10mM (DMSO)178,00€Osteostatin
CAS:Osteostatin, derived from parathyroid hormone-related protein (PTHrP) 107-111, has demonstrated properties conducive to bone repair in animal models presentingFórmula:C27H41N9O8Forma y color:SolidPeso molecular:619.67(Tyr36)-pTH-Related Protein (1-36) (human, mouse, rat)
CAS:'(Tyr36)-pTH-Related Protein (1-36) (human, mouse, rat), a peptide, functions as a ligand for parathyroid hormone (PTH) receptors [1].'Fórmula:C194H303N59O53Peso molecular:4309.85THR-β agonist 2 diacetate
THR-β agonist 2 diacetate (Compound 3) is a potent THR-β agonist with potential applications in researching metabolic disorders such as obesity, hyperlipidemia, hypercholesterolemia, and diabetes, as well as other conditions like steatosis and non-alcoholic steatohepatitis (NASH), atherosclerosis, and other related diseases and conditions.Forma y color:Odour SolidpTH (1-37) (human)
CAS:pTH (1-37) human fragment boosts cAMP, alkaline phosphatase, growth, and BMD, potential for osteoporosis research.Fórmula:C195H316N58O54S2Forma y color:SolidPeso molecular:4401.08DPC-AJ1951 TFA
DPC-AJ1951 TFA is a 14 amino acid peptide, potent PTH/PPR agonist, tested in bone resorption assays.Fórmula:C78H128F3N23O21Forma y color:SolidPeso molecular:1781.02Calcitonin, eel
CAS:Calcitonin from eel regulates calcium and is key in studying postmenopausal osteoporosis.
Fórmula:C146H241N43O47S2Pureza:98%Forma y color:White PowderPeso molecular:3414.91pTH-Related Protein (1-34) amide (human, mouse, rat)
CAS:Human PTHrP-(1-34)NH2, also known as PTH-Related Protein (1-34) amide for human, mouse, and rat, is the N-terminal fragment of PTHrP.Forma y color:SolidHuman PTHrP-(1-36)
CAS:Human PTHrP-(1-36) is a secreted form of parathyroid hormone-related protein that exhibits anticalciuric effects and promotes beta cell function andFórmula:C191H305N59O52Forma y color:SolidPeso molecular:4259.83Trh-gly
CAS:TRH-glycine (TRH-gly) serves as a precursor to thyrotropin-releasing hormone (TRH), capable of inducing the release of thyrotropin (TSH) and prolactin [1].Fórmula:C18H24N6O6Forma y color:SolidPeso molecular:420.42Human PTH-(1-31) amide
CAS:Human PTH-(1-31) amide, an analog of PTH, effectively stimulates phosphatidylcholine hydrolysis and promotes the release of adenylyl cyclase [1].Fórmula:C162H270N50O46S2Forma y color:SolidPeso molecular:3718.31Osteostatin (1-5) amide (human, bovine, dog, horse, mouse, rabbit, rat)
CAS:Osteostatin (1-5) amide (human, bovine, dog, horse, mouse, rabbit, rat), also known as Human PTHrP (107-111) amide, is a C-terminal fragment of parathyroidFórmula:C27H42N10O7Peso molecular:618.69NH-3
CAS:NH-3, an orally active THR antagonist with a 55 nM IC50, blocks thyroid hormone binding and cofactor recruitment.Fórmula:C28H27NO6Pureza:97.79% - 99.40%Forma y color:SolidPeso molecular:473.52Ref: TM-T40548
1mg217,00€5mg550,00€10mg792,00€25mg1.206,00€50mg1.605,00€100mg2.175,00€500mg4.389,00€1mL*10mM (DMSO)492,00€Parathyroid hormone (1-34) (rat)
CAS:Parathyroid hormone (PTH) receptor agonist. Increases serum PTH levels and bone mass in rats.Fórmula:C180H291N55O48S2Pureza:98%Forma y color:SolidPeso molecular:4057.74DPC-AJ1951
CAS:Potent 14 amino acid peptide agonist of the parathyroid hormone (PTH) receptor (EC50 = 26 nM).Fórmula:C76H127N23O19Pureza:98%Forma y color:SolidPeso molecular:1666.98Prepro-TRH-(160-169)
CAS:Prepro-TRH-(160-169), a pro-TRH peptide, enhances TRH-stimulated TSH secretion.Fórmula:C54H75N11O18SForma y color:SolidPeso molecular:1198.3Eprotirome
CAS:Eprotirome (KB2115), a synthetic thyroid hormone mimetic, is a thyroid hormone receptor agonist.Fórmula:C18H17Br2NO5Pureza:98.42% - 98.56%Forma y color:SolidPeso molecular:487.14Ref: TM-T5360
2mg34,00€5mg50,00€10mg80,00€25mg145,00€50mg222,00€100mg356,00€200mg522,00€1mL*10mM (DMSO)52,00€(D-Trp12,Tyr34)-pTH (7-34) amide (bovine) acetate
D-Trp12,Tyr34-pTH(7-34) (bovine) is a PTH antagonist with a Ki of 69 nM in bovine kidneys.Pureza:96.84%Forma y color:LiquidPeso molecular:N/AResmetirom
CAS:Resmetirom (MGL-3196) is a THR-β agonist (EC50=0.21 μM), with high selectivity and oral activity. High-Quality, Low-Cost!Fórmula:C17H12Cl2N6O4Pureza:99.05% - >99.99%Forma y color:SolidPeso molecular:435.22Ref: TM-T3595
1mg39,00€2mg51,00€5mg87,00€10mg126,00€25mg213,00€50mg343,00€100mg509,00€500mg1.130,00€1mL*10mM (DMSO)92,00€Sobetirome
CAS:Sobetirome (IACS-010759) is a selective agonist of thyroid hormone receptor β (TRβ) and binds selectively to TRβ-1 (EC50: 0.16 μM).Fórmula:C20H24O4Pureza:98.08% - 98.25%Forma y color:SolidPeso molecular:328.4REVERSE T3
CAS:Reverse T3 (3,3',5'-triiodo-L-thyronine) inhibits the increase of sodium current generated by other thyroid hormone analogs in neonatal rat myocytes.Fórmula:C15H12I3NO4Pureza:95.99% - 97.89%Forma y color:PowderPeso molecular:650.973,3',5-Triiodothyronine-(tyrosine ring-13C6)
CAS:3,3',5-Triiodothyronine-(tyrosine ring-13C6) is the 13C labeled compound of 3,3',5-Triiodothyronine. 3,3',5-Triiodothyronine has a CAS number of 5817-39-0.
Fórmula:C4C11H12I3NO4Forma y color:SolidPeso molecular:656.93KAT681
CAS:KAT681 is a liver selective thyromimetic.Fórmula:C24H22FNNaO6Pureza:98%Forma y color:SolidPeso molecular:462.429Glutaurine aceate
Glutaurine aceate containing glutamine and taurine residues is an orally active hormone of the parathyroid.Fórmula:C9H18N2O8SPureza:98%Forma y color:SoildPeso molecular:314.31Azetirelin
CAS:Azetirelin, as a TRH analog, has a more potent effect than TRH on the central nervous system.Fórmula:C15H20N6O4Pureza:99.72%Forma y color:SolidPeso molecular:348.36TR antagonist 1
CAS:TR antagonist 1 is a highly potent thyroid hormone receptor (TR) antagonist that can be used to study diseases caused by endocrine abnormalities.Fórmula:C25H23Br2NO4Pureza:99.57%Forma y color:SolidPeso molecular:561.26MB-07344
CAS:MB-07344 is a selective THR-β (thyroid hormone receptor β) agonist with a Ki of 2.17 nM, capable of reducing plasma total cholesterol (TPC).Fórmula:C19H25O5PPureza:99.32%Forma y color:SolidPeso molecular:364.37CO23
CAS:CO23 is a blood-brain barrier penetrant and selective TRα agonist and can be used in studies about the regulation of growth and development.Fórmula:C19H18I2N2O4Pureza:98.08%Forma y color:SolidPeso molecular:592.17DS08210767
CAS:DS08210767 is a highly potent, orally bioavailable PTHR1 antagonist with IC50 of 90 nM.Fórmula:C31H39N5O2Pureza:98.79%Forma y color:SolidPeso molecular:513.67MB-07811
CAS:MB-07811 (VK-2809) is an orally active HepDirect prodrug of MB07344 with cholesterol and triglycerides lowering activity.Fórmula:C28H32ClO5PPureza:99.74% - 99.94%Forma y color:SolidPeso molecular:514.98MLS000389544
CAS:MLS000389544 is a selective and potent thyroid hormone receptor β (TRβ) antagonist with a methylsulfonyl nitrobenzoic acid structure. It effectively inhibits the interaction between TRβ and steroid receptor coactivator 2 (SRC2).Fórmula:C20H24N2O7SForma y color:SolidPeso molecular:436.479
