Receptor de andrógenos
El receptor de andrógenos (AR) es un receptor hormonal nuclear que se activa al unirse a andrógenos, como la testosterona y la dihidrotestosterona. Este receptor juega un papel crucial en el desarrollo y mantenimiento de las características masculinas, así como en la regulación de varios procesos fisiológicos, incluyendo el crecimiento muscular, la libido y la densidad ósea. Los inhibidores del receptor de andrógenos son ampliamente estudiados en el contexto del cáncer de próstata, donde la señalización del AR a menudo está sobreexpresada. En CymitQuimica, ofrecemos una gama de moduladores del receptor de andrógenos de alta calidad para apoyar su investigación en endocrinología, biología del cáncer y regulación hormonal.
Se han encontrado 207 productos de "Receptor de andrógenos"
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N-desmethyl Enzalutamide
CAS:<p>N-desmethyl Enzalutamide (N-desmethyl MDV 3100) is the active Enzalutamide metabolite.It is the active metabolite of Enzalutamide.</p>Fórmula:C20H14F4N4O2SPureza:99.74%Forma y color:SolidPeso molecular:450.41Enzalutamide carboxylic acid
CAS:<p>Enzalutamide carboxylic acid is an antagonist of androgen receptor (AR) .</p>Fórmula:C20H13F4N3O3SPureza:97.88%Forma y color:SolidPeso molecular:451.39Clascoterone
CAS:<p>Clascoterone (CB-03-01) is a new topical and peripherally selective androgen antagonist.</p>Fórmula:C24H34O5Pureza:99.2% - 99.64%Forma y color:SolidPeso molecular:402.52LY2452473
CAS:<p>LY2452473 (OPK 88004) is an orally available and selective androgen receptor modulator with potential anticancer activity for the study of prostate cancer.</p>Fórmula:C22H22N4O2Pureza:99.72%Forma y color:SolidPeso molecular:374.44Masofaniten
CAS:<p>Masofaniten (EPI-7386) is an orally active androgen receptor (AR) inhibitor with antitumor activity for the study of prostate and breast cancer.</p>Fórmula:C24H24Cl2N4O4SPureza:98.42% - 98.66%Forma y color:SolidPeso molecular:535.44AR antagonist 6
CAS:<p>AR antagonist 6 (compound 6i), a diphenyl ether androgen receptor (AR) antagonist, binds to the AR with an affinity of 120 nM. It demonstrates low toxicity and effective in vitro activity in the golden Syrian hamster ear model. [19] [1]</p>Fórmula:C16H12F3NO2Forma y color:SolidPeso molecular:307.27GDC-2992
CAS:<p>GDC-2992 is a selective androgen receptor (AR) degradator that degrades AR and inhibits proliferation in VCaP cells,CRPC.</p>Fórmula:C45H51ClN8O5Pureza:99.82%Forma y color:SoildPeso molecular:819.39Estromustine
CAS:<p>Estromustine, an active metabolite of estramustine phosphate, is used to treat prostate cancer.</p>Fórmula:C23H29Cl2NO3Forma y color:SolidPeso molecular:438.39Procymidone
CAS:<p>Procymidone is a broad-spectrum fungicide that inhibits fungal glycerol triester synthesis, thereby disrupting hyphal growth. androgen receptor (AR) antagonist</p>Fórmula:C13H11Cl2NO2Pureza:99.86%Forma y color:Colorless SolidPeso molecular:284.14JNJ-37654032
CAS:<p>JNJ-37654032: orally active, nonsteroidal SARM. Mixed AR agonist/antagonist. Selective for muscle, grows levator ani, max at 3mg/kg, ED(50) 0.8mg/kg.</p>Fórmula:C11H7Cl2F3N2OForma y color:SolidPeso molecular:311.09BMS-564929
CAS:<p>BMS-564929 is an AR agonist that upregulates the expression and activity of fat-producing enzymes, reducing VAT content and lipid levels.</p>Fórmula:C14H12ClN3O3Pureza:98.17%Forma y color:SolidPeso molecular:305.72(R)-Bicalutamide
CAS:<p>(R)-Bicalutamide, an AR antagonist with antitumor properties, is crucial in prostate cancer research.</p>Fórmula:C18H14F4N2O4SForma y color:SolidPeso molecular:430.37LG-121071
CAS:<p>LG-121071: oral SARM, high-affinity AR full agonist, Ki=17 nM.</p>Fórmula:C15H15F3N2OPureza:98%Forma y color:SolidPeso molecular:296.29Honokiol DCA
CAS:<p>Honokiol DCA inhibits DRP1, enhances respiration via mitochondrial repair, and is active against Vemurafenib-resistant melanoma.</p>Fórmula:C22H18Cl4O4Forma y color:SolidPeso molecular:488.19Lubabegron fumarate
CAS:<p>Lubabegron (LY591281, LY488756 fumarate) is a beta-agonist approved in 2018 to lower ammonia in cattle waste, aiding environment and health.</p>Fórmula:C29H29N3O3SC4H4O4Forma y color:SolidPeso molecular:557.66Gumelutamide
CAS:<p>Gumelutamide, a tetrahydropyridopyrimidine compound, functions as both an antiandrogen and an antineoplastic agent by acting as an androgen antagonist.</p>Fórmula:C22H21ClN6OForma y color:SolidPeso molecular:420.89TFM-4AS-1
CAS:<p>androgen receptor modulator</p>Fórmula:C27H33F3N2O2Pureza:98%Forma y color:SolidPeso molecular:474.56HG122
CAS:<p>HG122 promotes AR degradation via proteasome, inhibiting castration-resistant prostate cancer.</p>Fórmula:C15H13N5O5Forma y color:SolidPeso molecular:343.29Androgen receptor antagonist 4
CAS:<p>Compound AT2 is an AR inhibitor with anticancer effects, blocking DHT action and AR nuclear translocation (IC50=0.15μM).</p>Fórmula:C22H18ClNForma y color:SolidPeso molecular:331.84AZD3514
CAS:<p>AZD3514 is a potent and oral androgen receptor downregulator with Ki of 2.2 μM and has ability of reducing AR protein expression.Phase 1.</p>Fórmula:C25H32F3N7O2Pureza:98.09%Forma y color:SolidPeso molecular:519.56
