Receptor de andrógenos
El receptor de andrógenos (AR) es un receptor hormonal nuclear que se activa al unirse a andrógenos, como la testosterona y la dihidrotestosterona. Este receptor juega un papel crucial en el desarrollo y mantenimiento de las características masculinas, así como en la regulación de varios procesos fisiológicos, incluyendo el crecimiento muscular, la libido y la densidad ósea. Los inhibidores del receptor de andrógenos son ampliamente estudiados en el contexto del cáncer de próstata, donde la señalización del AR a menudo está sobreexpresada. En CymitQuimica, ofrecemos una gama de moduladores del receptor de andrógenos de alta calidad para apoyar su investigación en endocrinología, biología del cáncer y regulación hormonal.
Se han encontrado 207 productos de "Receptor de andrógenos"
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MI-136
CAS:<p>MI-136 inhibits expression of androgen receptor (AR) target genes that DHT induced.</p>Fórmula:C23H21F3N6SPureza:98.63% - 99.12%Forma y color:SolidPeso molecular:470.51Apalutamide
CAS:<p>Apalutamide (ARN-509) is a small molecule and androgen receptor (AR) antagonist with potential antineoplastic activity.</p>Fórmula:C21H15F4N5O2SPureza:99.03% - 99.91%Forma y color:SolidPeso molecular:477.43S-23
CAS:<p>S-23 ((S)-3-(4-chloro-3-fluorophenoxy)-N-(4-cyano-3-(trifluoromethyl)phenyl)-2-hydroxy-2-methylpropanamide) is an oral selective androgen receptor modulator (</p>Fórmula:C18H13ClF4N2O3Pureza:99.55%Forma y color:SolidPeso molecular:416.75Iprodione
CAS:<p>Iprodione is a fungicide. Iprodione is also used in cannabis testing kits as a component of pesticide mixes.</p>Fórmula:C13H13Cl2N3O3Pureza:98.82%Forma y color:Colorless Crystals Cream To Colorless Odorless PowderPeso molecular:330.17Testosterone undecanoate
CAS:<p>Testosterone undecanoate is a metabolite of Testosterone, which is a promising androgen for male hormonal contraception.</p>Fórmula:C30H48O3Pureza:99.45% - 99.788%Forma y color:White Crystalline PowderPeso molecular:456.7CLP-3094
CAS:<p>CLP-3094 (2-([2-(4-CHLOROPHENOXY)ETHYL]THIO)-1H-BE) is a potent androgen receptor BF3 (binding function 3) inhibitor.</p>Fórmula:C15H13ClN2OSPureza:99.84%Forma y color:SolidPeso molecular:304.79AC-262536
CAS:<p>AC-262536 is a selective androgen receptor (SAR) modulator and exhibits potent agonist activity at the androgen receptor.</p>Fórmula:C18H18N2OPureza:99.88%Forma y color:SolidPeso molecular:278.35Triptophenolide
CAS:<p>Triptophenolide (Hypolide) is a compound isolated from Tripterygium wilfordii Hook with anti-inflammatory activity.</p>Fórmula:C20H24O3Pureza:98.07% - ≥95%Forma y color:White PowderPeso molecular:312.4Boldenone Undecylenate
CAS:<p>Boldenone Undecylenate (Parenabol) is a synthetic steroid.</p>Fórmula:C30H44O3Pureza:99.39%Forma y color:Light Yellow Oily MatterPeso molecular:452.67JNJ-63576253 free base
CAS:<p>JNJ-63576253 free base (TRC253) is a potent and orally active full antagonist of androgen receptor (AR). JNJ-63576253 can be used for the research of CRPC.</p>Fórmula:C23H21F3N6O2SPureza:98.32%Forma y color:SolidPeso molecular:502.51Dimethylcurcumin
CAS:<p>Dimethylcurcumin (ASC-J9) (ASC-J9) is an androgen receptor degradation enhancer.</p>Fórmula:C23H24O6Pureza:97.36% - 98.96%Forma y color:SolidPeso molecular:396.43Nandrolone phenylpropionate
CAS:<p>Nandrolone phenylpropionate (Nandrolone phenpropionate) is an androgen receptor agonist. It mainly used to treat women with breast cancer and osteoporosis</p>Fórmula:C27H34O3Pureza:99.2% - 99.46%Forma y color:White Or Milky Crystalline PowderPeso molecular:406.56JNJ-63576253
CAS:<p>JNJ-63576253 is a Clinical Stage Androgen Receptor Antagonist for F877L Mutant and Wild-Type Castration-Resistant Prostate Cancer (mCRPC).</p>Fórmula:C23H22ClF3N6O2SPureza:98.71%Forma y color:SolidPeso molecular:538.97Ailanthone
CAS:<p>Ailanthone (Δ13-Dehydrochaparrinone) is an effective inhibitor of both full-length androgen receptor (AR) (IC50: 69 nM) and constitutively active truncated AR</p>Fórmula:C20H24O7Pureza:99.71% - 99.96%Forma y color:SolidPeso molecular:376.43-(7,7-dimethyl-5-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyridin-2-yl)-1H-indole-7-carbonitrile
CAS:<p>3-[7 ,7- dimethyl-5-oxo -6H-pyrrolo[3,4-b]pyridin-2-yI]-1H-indole-7 -carbonitrile is an androgen receptor modulator.</p>Fórmula:C18H14N4OPureza:98.41%Forma y color:SolidPeso molecular:302.33ARD-2128
CAS:<p>ARD-2128: potent oral PROTAC that degrades AR, curbing prostate cancer growth with no toxicity.</p>Fórmula:C45H50ClN7O6Pureza:98.8%Forma y color:SolidPeso molecular:820.372-hydroxy Flutamide
CAS:<p>2-hydroxy Flutamide is competitive inhibition of androgen receptor (AR) for the treatment of prostate cancer</p>Fórmula:C11H11F3N2O4Pureza:99.45% - 99.82%Forma y color:SolidPeso molecular:292.21AH-3960
CAS:<p>AH-3960 是一种甲状腺激素受体 1 (PTHR1) 激动剂。</p>Fórmula:C13H22N4O3Pureza:98.44%Forma y color:SolidPeso molecular:282.34DSRM-3716
CAS:<p>Isoquinoline, 5-iodo- (9CI) is a potent and selective inhibitor of SARM1(IC50 = 75 nM) by preventing axonal degeneration and by allowing functional recovery of</p>Fórmula:C9H6INPureza:97.28% - 99.785%Forma y color:SolidPeso molecular:255.06Bavdegalutamide
CAS:<p>Bavdegalutamide (ARV-110) is a PROTAC degrader of androgen receptor (AR).</p>Fórmula:C41H43ClFN9O6Pureza:97.17% - 99.04%Forma y color:SolidPeso molecular:812.29N-desmethyl Enzalutamide
CAS:<p>N-desmethyl Enzalutamide (N-desmethyl MDV 3100) is the active Enzalutamide metabolite.It is the active metabolite of Enzalutamide.</p>Fórmula:C20H14F4N4O2SPureza:99.74%Forma y color:SolidPeso molecular:450.41Enzalutamide carboxylic acid
CAS:<p>Enzalutamide carboxylic acid is an antagonist of androgen receptor (AR) .</p>Fórmula:C20H13F4N3O3SPureza:97.88%Forma y color:SolidPeso molecular:451.39Clascoterone
CAS:<p>Clascoterone (CB-03-01) is a new topical and peripherally selective androgen antagonist.</p>Fórmula:C24H34O5Pureza:99.2% - 99.64%Forma y color:SolidPeso molecular:402.52LY2452473
CAS:<p>LY2452473 (OPK 88004) is an orally available and selective androgen receptor modulator with potential anticancer activity for the study of prostate cancer.</p>Fórmula:C22H22N4O2Pureza:99.72%Forma y color:SolidPeso molecular:374.44Masofaniten
CAS:<p>Masofaniten (EPI-7386) is an orally active androgen receptor (AR) inhibitor with antitumor activity for the study of prostate and breast cancer.</p>Fórmula:C24H24Cl2N4O4SPureza:98.42% - 98.66%Forma y color:SolidPeso molecular:535.44AR antagonist 6
CAS:<p>AR antagonist 6 (compound 6i), a diphenyl ether androgen receptor (AR) antagonist, binds to the AR with an affinity of 120 nM. It demonstrates low toxicity and effective in vitro activity in the golden Syrian hamster ear model. [19] [1]</p>Fórmula:C16H12F3NO2Forma y color:SolidPeso molecular:307.27GDC-2992
CAS:<p>GDC-2992 is a selective androgen receptor (AR) degradator that degrades AR and inhibits proliferation in VCaP cells,CRPC.</p>Fórmula:C45H51ClN8O5Pureza:99.82%Forma y color:SoildPeso molecular:819.39Estromustine
CAS:<p>Estromustine, an active metabolite of estramustine phosphate, is used to treat prostate cancer.</p>Fórmula:C23H29Cl2NO3Forma y color:SolidPeso molecular:438.39Procymidone
CAS:<p>Procymidone is a broad-spectrum fungicide that inhibits fungal glycerol triester synthesis, thereby disrupting hyphal growth. androgen receptor (AR) antagonist</p>Fórmula:C13H11Cl2NO2Pureza:99.86%Forma y color:Colorless SolidPeso molecular:284.14JNJ-37654032
CAS:<p>JNJ-37654032: orally active, nonsteroidal SARM. Mixed AR agonist/antagonist. Selective for muscle, grows levator ani, max at 3mg/kg, ED(50) 0.8mg/kg.</p>Fórmula:C11H7Cl2F3N2OForma y color:SolidPeso molecular:311.09BMS-564929
CAS:<p>BMS-564929 is an AR agonist that upregulates the expression and activity of fat-producing enzymes, reducing VAT content and lipid levels.</p>Fórmula:C14H12ClN3O3Pureza:98.17%Forma y color:SolidPeso molecular:305.72(R)-Bicalutamide
CAS:<p>(R)-Bicalutamide, an AR antagonist with antitumor properties, is crucial in prostate cancer research.</p>Fórmula:C18H14F4N2O4SForma y color:SolidPeso molecular:430.37LG-121071
CAS:<p>LG-121071: oral SARM, high-affinity AR full agonist, Ki=17 nM.</p>Fórmula:C15H15F3N2OPureza:98%Forma y color:SolidPeso molecular:296.29Honokiol DCA
CAS:<p>Honokiol DCA inhibits DRP1, enhances respiration via mitochondrial repair, and is active against Vemurafenib-resistant melanoma.</p>Fórmula:C22H18Cl4O4Forma y color:SolidPeso molecular:488.19Lubabegron fumarate
CAS:<p>Lubabegron (LY591281, LY488756 fumarate) is a beta-agonist approved in 2018 to lower ammonia in cattle waste, aiding environment and health.</p>Fórmula:C29H29N3O3SC4H4O4Forma y color:SolidPeso molecular:557.66Gumelutamide
CAS:<p>Gumelutamide, a tetrahydropyridopyrimidine compound, functions as both an antiandrogen and an antineoplastic agent by acting as an androgen antagonist.</p>Fórmula:C22H21ClN6OForma y color:SolidPeso molecular:420.89TFM-4AS-1
CAS:<p>androgen receptor modulator</p>Fórmula:C27H33F3N2O2Pureza:98%Forma y color:SolidPeso molecular:474.56HG122
CAS:<p>HG122 promotes AR degradation via proteasome, inhibiting castration-resistant prostate cancer.</p>Fórmula:C15H13N5O5Forma y color:SolidPeso molecular:343.29Androgen receptor antagonist 4
CAS:<p>Compound AT2 is an AR inhibitor with anticancer effects, blocking DHT action and AR nuclear translocation (IC50=0.15μM).</p>Fórmula:C22H18ClNForma y color:SolidPeso molecular:331.84AZD3514
CAS:<p>AZD3514 is a potent and oral androgen receptor downregulator with Ki of 2.2 μM and has ability of reducing AR protein expression.Phase 1.</p>Fórmula:C25H32F3N7O2Pureza:98.09%Forma y color:SolidPeso molecular:519.56AR antagonist 2
CAS:<p>AR antagonist 2 (compound 58) is a potent inhibitor of the androgen receptor (AR) (IC50: 0.95 μM).</p>Fórmula:C22H17ClFN5O2SForma y color:SolidPeso molecular:469.92AR antagonist 5
CAS:<p>Compound 30a, known as AR Antagonist 5, is a selective androgen receptor (AR) antagonist that demonstrates an IC 50 value of 134.8 nM. It exhibits favorable pharmacokinetic properties, characterized by high skin exposure and low plasma exposure [1].</p>Fórmula:C23H21F3N6O2Forma y color:SolidPeso molecular:470.45CSRM617
CAS:<p>CSRM617: selective ONECUT2 inhibitor, Kd 7.43 uM, binds OC2-HOX, induces apoptosis, tolerable in mouse prostate cancer model.</p>Fórmula:C10H13N3O5Pureza:98%Forma y color:SolidPeso molecular:255.23MK-4541
CAS:<p>MK-4541: oral, selective AR modulator, blocks 5α-reductase, curbs AR+ prostate cancer growth, effective in mouse model.</p>Fórmula:C22H31F3N2O3Forma y color:SolidPeso molecular:428.49(R)-UT-155
CAS:<p>(R)-UT-155 is a selective androgen receptor degrader (SARD) ligand.</p>Fórmula:C20H15F4N3O2Forma y color:SolidPeso molecular:405.35Carbazole derivative 1
CAS:<p>Carbazole derivative 1 is used to reduce androgen or oestrogen levels in mammals.</p>Fórmula:C18H13FN2Pureza:98%Forma y color:SolidPeso molecular:276.31VPC-3033
CAS:<p>VPC-3033 is an antagonist of the androgen receptor. It acts by inhibiting the LNCaP cell line as well as cell lines with the wild-type androgen receptor.</p>Fórmula:C21H14O2Pureza:98%Forma y color:SolidPeso molecular:298.33Androgen receptor antagonist 3
CAS:<p>Androgen receptor antagonist 3 (Compound C18) has anticancer activities that is an antagonist of androgen receptor (AR) (IC 50 = 2.4 μM) [1].</p>Fórmula:C22H18ClNForma y color:SolidPeso molecular:331.84RU 58642
CAS:<p>RU 58642 is an effective systemic antiandrogen for androgen-dependent disorders.</p>Fórmula:C15H11F3N4O2Pureza:98%Forma y color:SolidPeso molecular:336.27VPC-13789
CAS:<p>VPC-13789: potent, selective oral antiandrogen for CRPC with 0.19 μM IC50 in LNCaP cells.</p>Fórmula:C21H16F3N3OForma y color:SolidPeso molecular:383.37
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