Receptor de andrógenos
El receptor de andrógenos (AR) es un receptor hormonal nuclear que se activa al unirse a andrógenos, como la testosterona y la dihidrotestosterona. Este receptor juega un papel crucial en el desarrollo y mantenimiento de las características masculinas, así como en la regulación de varios procesos fisiológicos, incluyendo el crecimiento muscular, la libido y la densidad ósea. Los inhibidores del receptor de andrógenos son ampliamente estudiados en el contexto del cáncer de próstata, donde la señalización del AR a menudo está sobreexpresada. En CymitQuimica, ofrecemos una gama de moduladores del receptor de andrógenos de alta calidad para apoyar su investigación en endocrinología, biología del cáncer y regulación hormonal.
Se han encontrado 207 productos de "Receptor de andrógenos"
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JNJ-1250132
CAS:<p>JNJ-1250132 is a steroidal progesterone receptor modulator that inhibits binding of the receptor to DNA in vitro.</p>Fórmula:C33H41NO4Forma y color:SolidPeso molecular:515.68ERβ agonist-1
CAS:<p>ERβagonist-1 (Compound 8) functions as a dual-active selective ERβ agonist (EC50: 46.8 nM) and an AR antagonist (IC50: 1555 nM). By binding to ERβ, it activates its signaling pathways while simultaneously inhibiting AR activity. Retaining selective ERβ agonist activity in mouse models, ERβagonist-1 is applicable in prostate cancer research.</p>Fórmula:C25H36O2Forma y color:SolidPeso molecular:368.55EN1441
CAS:<p>EN1441 is a covalent degrader that targets the androgen receptor (AR) with an EC50 value of 4.2 μM, as well as its truncated variant AR-V7. It selectively and effectively degrades AR and AR-V7 in androgen-independent prostate cancer cells. EN1441 holds potential for research into androgen-independent prostate cancer.</p>Fórmula:C13H13ClN2O2Forma y color:SolidPeso molecular:264.708AR antagonist 11
CAS:<p>AR antagonist 11 (Compound c2) is a selective androgen receptor antagonist with an IC50 of 0.019 μM. It is also effective against the ARF877L/T878A mutant (IC50: 1.03 μM). Additionally, AR antagonist 11 inhibits LNCaP cell proliferation and decreases PSA protein expression (IC50: 0.54 μM). This compound is applicable in prostate cancer (PCa) research.</p>Fórmula:C20H17ClN2OForma y color:SolidPeso molecular:336.815Pentomone
CAS:<p>Pentomone (LY-113935) is an anti-androgen compound that acts as a prostate growth inhibitor.</p>Fórmula:C24H26O5Forma y color:SolidPeso molecular:394.46PF-998425
CAS:<p>non-steroidal androgen receptor (AR) antagonist</p>Fórmula:C14H14F3NOPureza:98%Forma y color:SolidPeso molecular:269.26YK11
CAS:<p>YK11 is an androgen receptor partial agonist that activates androgen receptor transcriptional activity in HEK293 cells overexpressing androgen receptors when used at a concentration of 0.1 μM, with osteogenic activity.</p>Fórmula:C25H34O6Pureza:98.91%Forma y color:SoildPeso molecular:430.53
