Enzima
Los inhibidores enzimáticos son moléculas que se unen a las enzimas y disminuyen su actividad. Estos inhibidores se utilizan ampliamente en la investigación para estudiar la cinética enzimática, la regulación y el papel de enzimas específicas en las vías metabólicas. Los inhibidores enzimáticos también son cruciales en el desarrollo de fármacos, ya que muchos agentes terapéuticos funcionan inhibiendo enzimas involucradas en procesos patológicos. Al dirigirse a las enzimas, estos inhibidores pueden modular las vías bioquímicas y ofrecer tratamientos potenciales para diversas enfermedades. En CymitQuimica, ofrecemos una amplia selección de inhibidores enzimáticos de alta calidad para apoyar su investigación en bioquímica, farmacología y descubrimiento de fármacos.
Subcategorías de "Enzima"
- Anhídrido carbónico(177 productos)
- Hidroxilasa(30 productos)
- MPO(2 productos)
- Reductasa(52 productos)
- Tirosinasa(67 productos)
Se han encontrado 3586 productos de "Enzima"
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hCA/Wnt/β-catenin-IN-1
<p>hCA/Wnt/β-catenin-IN-1 (Compd 15) serves as an inhibitor with selective affinity for hCA isoforms II, IX, and XII, exhibiting K i values of 33.6, 24.1, and 6.8</p>Forma y color:Odour SolidhCAII-IN-7
<p>hCAII-IN-7 (R-13) inhibits human CA I, II, IV, IX with K i of 60.7, 320.7, 2298, 35.2 nM respectively.</p>Fórmula:C20H25N3O4SForma y color:SolidPeso molecular:403.5hCAIX/XII-IN-11
<p>hCAIX/XII-IN-11 (Compound 6c) is an inhibitor of hCA IX and hCA XII, exhibiting Ki values of 0.7 μM for both isoforms. This compound is applicable in cancer research.</p>Fórmula:C13H10FN3O4Peso molecular:291.06553VM4-037
CAS:<p>VM4-037 is a PET imaging agent used for carbonic anhydrase IX.</p>Fórmula:C26H29FN6O7S2Forma y color:SolidPeso molecular:620.67Calmodulin-dependent Protein Kinase II fragment 290-309
CAS:Fórmula:C103H185N31O24SPeso molecular:2273.83hCA/VEGFR-2-IN-3
<p>hCA/VEGFR-2-IN-3 (compound 8j) is an indolinonylbenzenesulfonamide with potential as a dual inhibitor of cancer-associated hCA IX/XII and VEGFR-2.</p>Fórmula:C24H28N6O6SPureza:98%Forma y color:SolidPeso molecular:528.58hCAII-IN-8
CAS:<p>Compound CDy9 is a highly selective inhibitor of carbonic anhydrase (CA) with an IC50 value of 0.18 μM for hCA II.</p>Fórmula:C15H16N2O5SPureza:99.73%Forma y color:SoildPeso molecular:336.36Carbonic anhydrase inhibitor 29
<p>Carbonic anhydrase inhibitor29 (Compound 5d) is an inhibitor targeting carbonic anhydrase IX and XII, with an inhibition constant (Ki) of 26.6 nM for carbonic anhydrase IX and a Ki of 10.9 nM for carbonic anhydrase XII. Carbonic anhydrase inhibitor29 can be used in cancer research.</p>Forma y color:Odour SolidCAXII-IN-2
<p>CAXII-IN-2 (compound 3j) is a highly effective inhibitor of CAXII. It demonstrates inhibitory activity against CA IX and CAXII, with Ki values of 27.4 nM and 4.0 nM, respectively.</p>Fórmula:C16H13FNO4PForma y color:SolidPeso molecular:333.05662hCAI/II-IN-10
<p>hCAI/II-IN-10 (Compound 5d) is an inhibitor of human carbonic anhydrase I and II (hCA I and hCA II), with IC50 values of 4.32 nM and 3.89 nM, respectively.</p>Fórmula:C24H17Cl2N3O3S2Forma y color:SolidPeso molecular:530.446Tyrosinase-IN-38
<p>Tyrosinase-IN-38 (compound 6b) is a competitive inhibitor of tyrosinase, demonstrating an IC50 of 25.82 μM and exhibits antioxidant activity.</p>Forma y color:Odour SolidCAIX Inhibitor S4
CAS:<p>CAIX Inhibitor S4 (S4) is an effective inhibitor of carbonic anhydrase IX/XII with a Ki of 7 nM and 2 nM, respectively.</p>Fórmula:C15H17N3O4SPureza:99.07%Forma y color:SolidPeso molecular:335.38hCAIX-IN-19
<p>hCAIX-IN-19 is a sulfonamide inhibitor with an inhibition constant (KI) of 6.2 nM for hCAIX, exhibiting significant selectivity towards hCAIX over hCAI (hCA I/</p>Forma y color:Odour SolidCAIX/CAXII-IN-3
<p>CAIX/CAXII-IN-3 (compound 11) serves as an inhibitor for CAIX/CAXII, exhibiting an IC50 value of less than 65 nM. Additionally, this compound effectively inhibits the proliferation of human melanoma cells.</p>Forma y color:Odour SolidTyrosinase-IN-36
<p>Tyrosinase-IN-36 is a moderately potent inhibitor of tyrosine, exhibiting an inhibition percentage of 42.75% compared to kojic acid at a concentration of 100 μM and possesses antioxidant activity.</p>Forma y color:Odour SolidDOTA-XYIMSR-01
CAS:<p>DOTA-XYIMSR-01 is a molecular probe targeting CAIX, capable of being labeled with 177Lu for the treatment and localization of malignant gliomas. The uptake of [177Lu]Lu-XYIMSR-01 in U87MG tumors is 6.19% injected dose per gram (% ID/g), with a tumor-to-muscle uptake ratio of 20.14. In an orthotopic glioma model, co-administration with temozolomide significantly enhances survival rates and inhibits tumor growth in mice. DOTA-XYIMSR-01 shows potential for research in the field of cancer treatment.</p>Fórmula:C61H88N16O22S2Forma y color:SolidPeso molecular:1461.57IOX2-NH2-1
CAS:<p>IOX2-NH2-1 inhibits E. coli EGLN-3 (prolyl hydroxylase) with an IC50 of 0.02–1 μM.</p>Fórmula:C19H17N3O5Pureza:98.77% - 99.91%Forma y color:SoildPeso molecular:367.365,6-Dihydro-2H-pyran-2-one
CAS:<p>5,6-Dihydro-2H-pyran-2-one is a carbonic anhydrase 1/9 inhibitor that inhibits KB cell viability.</p>Fórmula:C5H6O2Forma y color:SolidPeso molecular:98.1TPH1-IN-1
<p>TPH1-IN-1 (compound 40) is a xanthine derivative that serves as an inhibitor of tryptophan hydroxylase TPH1, with an IC50 of 110.1 nM.</p>Fórmula:C21H18N6O4SForma y color:SolidPeso molecular:450.47DPP IV/hCA II-IN-1
CAS:<p>DPP IV/hCA II-IN-1: strong DPP IV & CA inhibitor, IC50=0.049μM (DPP IV), Ki=0.0361-3.034μM (CA II-IV).</p>Fórmula:C17H20N2O5SForma y color:SolidPeso molecular:364.42Proteinase K
CAS:Pureza:≥ 30units/mg (pH 7.5, 37°C, dried basis)Forma y color:White or almost white lyophilized powderPeso molecular:-hCAII-IN-6
<p>"hCAII-IN-6 (S-13) inhibits hCA II (4.4 nM) and isoforms I, IV, IX (9.2, 480.2, 14.7 nM). For glaucoma research."</p>Fórmula:C20H25N3O4SForma y color:SolidPeso molecular:403.5Peroxidase
CAS:Pureza:≥ 85units/mg (dry basis)Forma y color:Beige to light-brown, reddish brown or dark brown lyophilised powderPeso molecular:-P-Hydroxybenzoate Hydroxylase
CAS:Forma y color:Yellowish lyophilised powderPeso molecular:55 ~ 60 kDa2-Methoxy-4-propylphenol
CAS:<p>2-Methoxy-4-propylphenol is an inhibitor of human carbonic anhydrase isoenzymes 1/2/9/12 and has antifungal activity.</p>Fórmula:C10H14O2Forma y color:SolidPeso molecular:166.22Phenylsulfamide
CAS:<p>Phenylsulfamide (Compound 10), acting as an inhibitor of human carbonic anhydrase-II (hCA-II), exhibits a dissociation constant (Kd) of 45.50 μM and an</p>Fórmula:C6H8N2O2SForma y color:SolidPeso molecular:172.2Carbonic anhydrase inhibitor 30
<p>Carbonic anhydrase inhibitor30 (compound 17) is an inhibitor of carbonic anhydrase with Ki values of 2.13 μM for hCA I and 0.161 μM for hCA II[1].</p>Fórmula:C23H22FN3O5SForma y color:SolidPeso molecular:471.12642TPT-004
<p>TPT-004, a TPH inhibitor, exhibits superior pharmacokinetic and pharmacodynamic properties, and demonstrates efficacy in preclinical models for attenuating</p>Forma y color:Odour SolidTrypsin, bovine origin
CAS:Pureza:≥ 2000units/mg (USP)Forma y color:White or almost white crystalline powderPeso molecular:-hCA/VEGFR-2-IN-4
<p>hCA/VEGFR-2-IN-4 (compound 15b), an indolinylbenzenesulfonamide, serves as a potential dual inhibitor targeting cancer-related human carbonic anhydrases hCA IX/</p>Fórmula:C22H23FN6O5SPureza:98%Forma y color:SolidPeso molecular:502.52
