Hidroxilasa
Las hidroxilasas son una clase de enzimas que catalizan la hidroxilación de sustratos, añadiendo frecuentemente grupos hidroxilo (-OH) a posiciones específicas dentro de las moléculas. Estas enzimas están involucradas en una amplia variedad de rutas bioquímicas, incluyendo la síntesis de hormonas, procesos de desintoxicación y el metabolismo de fármacos. Los inhibidores y activadores de hidroxilasas son herramientas valiosas en la investigación de trastornos metabólicos, metabolismo de fármacos y regulación hormonal. En CymitQuimica, ofrecemos una selección de reactivos de hidroxilasas de alta calidad para apoyar su investigación en bioquímica, farmacología y regulación metabólica.
Se han encontrado 30 productos de "Hidroxilasa"
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p-Ethynylphenylalanine hydrochloride
CAS:<p>p-Ethynylphenylalanine hydrochloride (4-Ethynyl-L-phenylalanine HCL) is a novel, potent and specific inhibitor of TPH[1].</p>Fórmula:C11H12ClNO2Pureza:99.03%Forma y color:SolidPeso molecular:225.67Fenclonine
CAS:<p>Fenclonine (CP-10188) is a selective and irreversible inhibitor of tryptophan hydroxylase, a rate-limiting enzyme in the biosynthesis of serotonin.</p>Fórmula:C9H10ClNO2Pureza:98.81% - >99.99%Forma y color:Crystals From Methanol White SolidPeso molecular:199.63ACT-678689
CAS:<p>ACT-678689 (Compound Example 1.53.4) (Compound Example 1.53.4) is a tryptophan hydroxylase (TPH) inhibitor with an IC50 of 8 nM[1].</p>Fórmula:C23H22ClFN6O4S2Pureza:99.46%Forma y color:SolidPeso molecular:565.04Telotristat ethyl
CAS:<p>Telotristat ethyl (LX1606) is a orally-delivered inhibitor of tryptophan hydroxylase that reduces serotonin production.</p>Fórmula:C27H26ClF3N6O3Pureza:98% - 99.89%Forma y color:White SolidPeso molecular:574.98TPT-004
<p>TPT-004, a TPH inhibitor, exhibits superior pharmacokinetic and pharmacodynamic properties, and demonstrates efficacy in preclinical models for attenuating</p>Forma y color:Odour SolidIOX2-NH2-1
CAS:<p>IOX2-NH2-1 inhibits E. coli EGLN-3 (prolyl hydroxylase) with an IC50 of 0.02–1 μM.</p>Fórmula:C19H17N3O5Pureza:98.77% - 99.91%Forma y color:SoildPeso molecular:367.36TPH1-IN-1
<p>TPH1-IN-1 (compound 40) is a xanthine derivative that serves as an inhibitor of tryptophan hydroxylase TPH1, with an IC50 of 110.1 nM.</p>Fórmula:C21H18N6O4SForma y color:SolidPeso molecular:450.47GSK180
CAS:<p>GSK180 is a selective competitive inhibitor of kynurenine 3-monooxygenase (KMO; IC50: ~6 nM), an enzyme involved in tryptophan metabolism.</p>Fórmula:C10H7Cl2NO4Forma y color:SolidPeso molecular:276.07Cuprizone
CAS:<p>Cuprizone is a copper chelator.Cuprizone is used to induce schizophrenia in mice.Cuprizone induces oligodendrocyte death and induces a demyelination response.</p>Fórmula:C14H22N4O2Pureza:≥98%Forma y color:SolidPeso molecular:278.35Nepicastat hydrochloride
CAS:<p>Nepicastat hydrochloride (RS-25560-197 hydrochloride) is a selective, orally active, dopamine-beta-hydroxylase inhibitor that crosses the blood-brain barrier.</p>Fórmula:C14H15F2N3S·HClPureza:98.35% - 99.74%Forma y color:SolidPeso molecular:331.81FG-2216
CAS:<p>FG-2216 (YM-311) is a HIF-prolyl hydroxylase inhibitor for the PDH2 enzyme; orally bioavailable and induced reversible and significant Epo induction in vivo.</p>Fórmula:C12H9ClN2O4Pureza:97.1% - >99.99%Forma y color:SolidPeso molecular:280.66Tetrahydropapaverine hydrochloride
CAS:<p>Tetrahydropapaverine hydrochloride (Norlaudanosine HCl) , an analogue of salsolinol and tetrahydropapaveroline, has neurotoxicity on dopamine neurons.</p>Fórmula:C20H26ClNO4Pureza:99.08%Forma y color:White Crystal PowderPeso molecular:379.878Telotristat
CAS:<p>Telotristat, active metabolite of LX1606, is an oral tryptophan hydroxylase inhibitor with potential antiserotonergic effects.</p>Fórmula:C25H22ClF3N6O3Pureza:99.70%Forma y color:SolidPeso molecular:546.93Ro 61-8048
CAS:Ro 61-8048 is a potent and selective inhibitor of kynurenine hydroxylase with an IC50 value of 37 nM.Fórmula:C17H15N3O6S2Pureza:98% - >99.99%Forma y color:SolidPeso molecular:421.45p-Fluoro-L-phenylalanine
CAS:<p>p-Fluoro-L-phenylalanine: TH substrate, studies enzyme regulation, binds E. coli L-leucine receptor, KD 0.26μM.</p>Fórmula:C9H10FNO2Pureza:99.63%Forma y color:White To Off-White PowderPeso molecular:183.18Telotristat Etiprate
CAS:<p>Telotristat Etiprate (LX 1606 Hippurate) is an orally bioavailable, tryptophan hydroxylase (TPH) inhibitor with potential antiserotonergic activity.</p>Fórmula:C27H26ClF3N6O3·C9H9NO3Pureza:99.21% - 99.83%Forma y color:White SolidPeso molecular:754.15Mildronate
CAS:<p>Mildronate (Meldonium) is an inhibitor of biosynthesis of L-carnitine by gamma-butyrobetaine (GBB) hydroxylase and as a competitive inhibitor of renal carnitine</p>Fórmula:C6H14N2O2Pureza:99.94%Forma y color:White Crystalline PowderPeso molecular:146.19TETRAHYDROPIPERINE
CAS:<p>Tetrahydropiperine (Cosmoperine) is a natural product derived from piperine, can be used to treat convulsion, epilepsy, relieve pain, and control insects.</p>Fórmula:C17H23NO3Pureza:98.04% - 99.61%Forma y color:Off-White Low Melting Solid With Characteristic OdourPeso molecular:289.37Nepicastat
CAS:<p>Nepicastat (SYN117) is a potent, BBB-permeable, selective DBH inhibitor with IC50s of 8.5/9 nM in bovine/human.</p>Fórmula:C14H15F2N3SForma y color:SolidPeso molecular:295.35Guanoclor
CAS:<p>Guanoclor (VATENSOL) (INN), also known as guanochlor, is a sympatholytic drug. It is known to bind to non-adrenergic sites in pig kidney membranes.</p>Fórmula:C9H12Cl2N4OPureza:98.79%Forma y color:SolidPeso molecular:263.12SU 10603
CAS:<p>SU 10603 is a specific inhibitor of 17α-hydroxylase (also known as CYP17A1 and P450c17) used to study steroid hormone synthesis.</p>Fórmula:C15H12ClNOPureza:99.93% - 99.96%Forma y color:SolidPeso molecular:257.72Phenylthiazolylthiourea
CAS:<p>Phenylthiazolylthiourea ia a dopamine-beta-hydroxylase inhibitor.</p>Fórmula:C10H9N3S2Forma y color:SolidPeso molecular:235.33Telotristat besilate
CAS:<p>Telotristat besilate is an inhibitor of tryptophan hydroxylase.</p>Fórmula:C31H28ClF3N6O6SPureza:98%Forma y color:SolidPeso molecular:705.11(R)-Nepicastat HCl
CAS:<p>(R)-Nepicastat HCl (RS-25560-198 HCl), R-enantiomer, inhibits bovine/human dopamine-β-hydroxylase (IC50: 25.1/18.3 nM); not affecting other enzymes/receptors.</p>Fórmula:C14H15F2N3S·HClPureza:98%Forma y color:SolidPeso molecular:331.81LP-533401
CAS:<p>LP-533401 is an inhibitor of Tryptophan hydroxylase 1. It is used for regulates serotonin production in the gut.</p>Fórmula:C27H22F4N4O3Pureza:98%Forma y color:SolidPeso molecular:526.48Bupicomide
CAS:<p>Bupicomide is a dopamine β-hydroxylase inhibitor with antihypertensive and vasodilatory activity and may be used in the study of hypertension.</p>Fórmula:C10H14N2OPureza:99.84% - >99.99%Forma y color:SolidPeso molecular:178.23Diethyl-pythiDC
CAS:<p>Diethyl-pythiDC is an collagen prolyl 4-hydroxylase inhibitor.</p>Fórmula:C14H14N2O4SPureza:99.98%Forma y color:SolidPeso molecular:306.34LX-1031
CAS:<p>LX-1031 is an effective inhibitor of tryptophan 5-hydroxylase. LX-1031 decreases serotonin (5-HT) synthesis peripherally.</p>Fórmula:C28H25F3N4O4Pureza:97.123% - 98.97%Forma y color:SolidPeso molecular:538.52p-Ethynylphenylalanine
CAS:<p>p-Ethynylphenylalanine (4-Ethynyl-L-phenylalanine), a tryptophan hydroxylase (TPH) inhibitor, is competitive, effective, selective, and reversible, with a Ki of</p>Fórmula:C11H11NO2Pureza:97.57%Forma y color:SolidPeso molecular:189.21GSK 366
CAS:GSK 366 is a potent kynurenine-3-monooxygenase (KMO) inhibitor (IC50s: 0.7 nM and 2.3 nM for P. fluorescens-KMO and human KMO).Fórmula:C17H16ClN3O4Pureza:98%Forma y color:SolidPeso molecular:361.78
