NF-κB
El factor nuclear kappa-light-chain-enhancer de células B activadas (NF-κB) es un factor de transcripción que regula la expresión de genes involucrados en respuestas inmunitarias, inflamación, supervivencia celular y proliferación. El NF-κB se activa en respuesta a varios estímulos, incluidos citocinas, patógenos y señales de estrés. La desregulación de la señalización de NF-κB está asociada con enfermedades inflamatorias crónicas, cáncer y trastornos autoinmunes. En CymitQuimica, ofrecemos una selección integral de moduladores de la vía NF-κB para apoyar su investigación en inflamación, oncología y regulación inmunitaria.
Se han encontrado 445 productos de "NF-κB"
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GSK2983559 free acid
CAS:<p>GSK2983559 free acid selectively inhibits RIP2, reducing inflammatory cytokines in human bowel disease.</p>Fórmula:C21H23N4O7PS2Pureza:97.8700% - 98.61%Forma y color:SolidPeso molecular:538.53B022
CAS:<p>B022 is an NF-κB-induced kinase (NIK) inhibitor that protects the liver from inflammation and injury caused by oxidative stress and toxins.</p>Fórmula:C19H16ClN5OSPureza:99.74%Forma y color:SolidPeso molecular:397.88NFATc1-IN-1
CAS:<p>NFATc1-IN-1 (A04) inhibits RANKL-induced osteoclast formation with 1.57 μM IC50, blocking NFATc1 translocation.</p>Fórmula:C13H8F2INO2Pureza:99.64%Forma y color:SolidPeso molecular:375.11Zharp2-1
CAS:<p>Zharp2-1 is a RIPK2 inhibitor that alleviates MDP-induced peritonitis symptoms in mice and can be used to study inflammatory bowel disease (IBD).</p>Fórmula:C19H18N3O2PSPureza:99.41%Forma y color:SolidPeso molecular:383.4RIPK1-IN-9
CAS:<p>RIPK1-IN-9, a potent dihydronaphthone, selectively inhibits RIPK1 with IC50 of 2 nM (U937) and 1.3 nM (L929).</p>Fórmula:C26H25FN6O2Pureza:99.85%Forma y color:SolidPeso molecular:472.51HS271
CAS:<p>HS271 is a selective, highly potent and orally active IRAK4 inhibitor (IC50= 7.2 μM).</p>Fórmula:C21H24F3N5O2Pureza:98.79%Forma y color:SolidPeso molecular:435.44IRAK4-IN-20
CAS:<p>IRAK4-IN-20 is a potent and orally active IRAK4 inhibitor (IC50:3.55 nM).</p>Fórmula:C22H25F3N4O3Pureza:98.09%Forma y color:SolidPeso molecular:450.45GSK840
CAS:<p>GSK840 (GSK'840) is a receptor-interacting protein kinase 3 (RIP3 or RIPK3) inhibitor, which binds the RIP3 kinase domain (IC50: 0.9 nM), and inhibits kinase</p>Fórmula:C21H23N3O3Pureza:99.7%Forma y color:SolidPeso molecular:365.43PF-184
<p>PF-184: potent IKK-2 inhibitor, selective over 30+ kinases; useful for asthma & COPD research. IC50: 37 nM.</p>Fórmula:C32H32ClFN6O4Forma y color:SolidPeso molecular:619.09WEHI-345
CAS:<p>WEHI-345 is a potent and selective RIPK2 inhibitor which shows NOD signalling events yet prevents inflammatory cytokine production.</p>Fórmula:C22H23N7OPureza:>99.99%Forma y color:SolidPeso molecular:401.46RIPK1-IN-16
CAS:<p>RIPK1-IN-16 is an orally active, potent RIPK1 inhibitor that mitigates excessive inflammation via inhibition of RIPK1-mediated necroptosis in vivo.</p>Fórmula:C20H19N5O2SPureza:98%Forma y color:SolidPeso molecular:393.46Ginsenoside Rk1
CAS:<p>Ginsenoside Rk1 is a component created by processing the ginseng plant at high temperatures.</p>Fórmula:C42H70O12Pureza:98.46% - 99.13%Forma y color:SolidPeso molecular:767PF 184
CAS:<p>IKKβ inhibitor</p>Fórmula:C32H32ClFN6O4Pureza:98%Forma y color:SolidPeso molecular:619.09RIP1 kinase inhibitor 4
CAS:<p>RIP1 Kinase Inhibitor 4 (Compound 3) is an effective inhibitor of RIP1K, exhibiting an EC50 of ≤ 1000 nM [1].</p>Fórmula:C23H23N5Pureza:98%Forma y color:SolidPeso molecular:369.46IMD-biphenylC
CAS:<p>IMD-biphenylC: New, dual-action imidazoquinolinone dimer; inhibits tumor growth, low inflammation/toxicity.</p>Fórmula:C35H33N5O3Pureza:98%Forma y color:SolidPeso molecular:571.67CGA-JK3
CAS:<p>CGA-JK3 is an IkappaB kinase inhibitor in innate immune process.</p>Fórmula:C15H19NO3Pureza:98%Forma y color:SolidPeso molecular:261.32PK68
CAS:<p>PK68 selectively inhibits RIPK1 (IC50=90nM), potentially useful in inflammation and cancer metastasis studies.</p>Fórmula:C22H24N4O3SPureza:98.09% - 99.64%Forma y color:SolidPeso molecular:424.52IRAK inhibitor 3
CAS:<p>IRAK inhibitor 3 is an interleukin-1 (IL-1) receptor-associated kinase (IRAK) modulator.</p>Fórmula:C21H21N5O4SPureza:98.86%Forma y color:SolidPeso molecular:439.49IMD-vanillin
CAS:<p>IMD-vanillin is a novel compound characterized as an imidazoquinolinone-derived dimer with NF-κB immunomodulatory properties.</p>Fórmula:C37H45N7O4Pureza:98%Forma y color:SolidPeso molecular:651.8TBK1-IN-1
CAS:<p>TBK1-IN-1 is a TANK-binding kinase 1 inhibitor with anticancer activity.TBK1-IN-1 inhibits the expression of TBK1 downstream target genes, cxcl10 and ifnβ.</p>Fórmula:C27H37N7O2Pureza:>99.99%Forma y color:SolidPeso molecular:491.63
