NF-κB
El factor nuclear kappa-light-chain-enhancer de células B activadas (NF-κB) es un factor de transcripción que regula la expresión de genes involucrados en respuestas inmunitarias, inflamación, supervivencia celular y proliferación. El NF-κB se activa en respuesta a varios estímulos, incluidos citocinas, patógenos y señales de estrés. La desregulación de la señalización de NF-κB está asociada con enfermedades inflamatorias crónicas, cáncer y trastornos autoinmunes. En CymitQuimica, ofrecemos una selección integral de moduladores de la vía NF-κB para apoyar su investigación en inflamación, oncología y regulación inmunitaria.
Se han encontrado 360 productos para "NF-κB".
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
Lidocaine
CAS:Lidocaine, an amide local anesthetic, reduces pain and inflammation by dampening ICAM-1, cytokines, and neutrophil influx.Fórmula:C14H22N2OPureza:99.88% - >99.99%Forma y color:White SolidPeso molecular:234.34Theophylline monohydrate
CAS:Theophylline monohydrate (Quibron) appears to inhibit phosphodiesterase and prostaglandin production, regulate calcium flux and intracellular calciumFórmula:C7H8N4O2·H2OPureza:99.78%Forma y color:SolidPeso molecular:198.18Oxaprozin
CAS:Oxaprozin (Oxaprozinum) is a Nonsteroidal Anti-inflammatory Drug.Fórmula:C18H15NO3Pureza:98.53%Forma y color:White SolidPeso molecular:293.32Dihydroartemisinin
CAS:Dihydroartemisinin (Artenimol) is an antimalarial drug. High-Quality, Low-Cost!Fórmula:C15H24O5Pureza:98% - 99.41%Forma y color:SolidPeso molecular:284.35Sulindac
CAS:Sulindac (Sulindac sulfoxide) is a sulfinylindene derivative prodrug with potential antineoplastic activity.Fórmula:C20H17FO3SPureza:99.09% - 99.15%Forma y color:White SolidPeso molecular:356.415-Aminosalicylic Acid
CAS:5-Aminosalicylic Acid (5-ASA) is a specific PPARγ agonist and also inhibits P21-activated kinase 1 (PAK1) and NF-Κb. High-Quality, Low-Cost!Fórmula:C7H7NO3Pureza:98.88% - 99.49%Forma y color:Red SolidPeso molecular:153.14Lidocaine Hydrochloride hydrate
CAS:Lidocaine Hydrochloride hydrate is an amide local anesthetic, has anti-inflammatory property.Fórmula:C14H22N2O·HCl·H2OPureza:99.95%Forma y color:SolidPeso molecular:288.824-Hydroxychalcone
CAS:4-Hydroxychalcone (P-Cinnamoylphenol) attenuates hyperaldosteronism, inflammation, and renal injury in cryptochrome-null mice.Fórmula:C15H12O2Pureza:99.75%Forma y color:SolidPeso molecular:224.25DCZ0415
CAS:DCZ0415: Potent TRIP13 inhibitor; combats myeloma in vitro, in vivo, and in drug-resistant patients; hinders DNA repair and NF-κB activity.Fórmula:C23H20N2O2Pureza:99.34% - 99.95%Forma y color:White SolidPeso molecular:356.42Ref: TM-T10981
1mg50,00€5mg110,00€1mL*10mM (DMSO)119,00€10mg178,00€25mg334,00€50mg505,00€100mg707,00€200mg973,00€Asatone
CAS:Asatone from Radix et Rhizoma Asari has anti-inflammatory properties, acting on NF-κB and suppressing p-MAPK pathways (ERK, JNK, p38).Fórmula:C24H32O8Pureza:99.84% - 99.92%Forma y color:SolidPeso molecular:448.51Ref: TM-T10383
1mg77,00€5mg167,00€1mL*10mM (DMSO)178,00€10mg260,00€25mg440,00€50mg628,00€100mg872,00€200mg1.153,00€Baicalin
CAS:Baicalin (Baicalein 7-O-β-D-glucuronide) is a prolyl endopeptidase inhibitor isolated from scutellaria baicalensis, with antioxidant, anti-tumor, anti-HIVFórmula:C21H18O11Pureza:90.08% - 99.32%Forma y color:SolidPeso molecular:446.36Ref: TM-T2775
50mg34,00€100mg49,00€200mg49,00€1mL*10mM (DMSO)50,00€500mg55,00€1g80,00€2g102,00€5g152,00€Nimbolide
CAS:Nimbolide, from neem, inhibits CDK4/6, NF-κB, Wnt, PI3K-Akt, MAPK, JAK-STAT pathways and induces apoptosis.Fórmula:C27H30O7Pureza:95.84% - 99.4%Forma y color:SolidPeso molecular:466.52Ref: TM-T16324
1mg67,00€5mg167,00€1mL*10mM (DMSO)180,00€10mg289,00€25mg595,00€50mg820,00€100mg1.108,00€200mg1.440,00€Sinomenine hydrochloride
CAS:Sinomenine hydrochloride (Kukoline hydrochloride) is extracted from Sinomenium Acutum Rehderett Wilson.Fórmula:C19H24ClNO4Pureza:99.43%Forma y color:White SolidPeso molecular:365.85Sodium salicylate
CAS:Sodium salicylate (2-Hydroxybenzoic acid sodium salt), a metabolite of acetylsalicylic acid, can inhibit NF-kB and reduce oxidative stress.Fórmula:C7H5NaO3Pureza:99.36% - 99.92%Forma y color:SolidPeso molecular:160.11Sulfasalazine
CAS:Sulfasalazine (Azulfidine) is a synthetic salicylic acid derivative. Sulfasalazine induces ferroptosis and inhibits NF-κB. Cost effective and quality assured.Fórmula:C18H14N4O5SPureza:98.00% - 99.28%Forma y color:Yellow SolidPeso molecular:398.39CDDO-dhTFEA
CAS:CDDO-dhTFEA, a synthetic oleanane triterpenoid, effectively activates Nrf2 while inhibiting the NF-κB pro-inflammatory transcription factor.Fórmula:C33H45F3N2O3Pureza:95.61% - 99.59%Forma y color:SolidPeso molecular:574.72Ref: TM-T13604
1mg66,00€2mg96,00€5mg144,00€1mL*10mM (DMSO)177,00€10mg241,00€25mg485,00€50mg700,00€100mg982,00€500mg1.953,00€Indacaterol maleate
CAS:Indacaterol maleate (QAB149) is an ultra-long-acting β-adrenoceptor agonist.Fórmula:C28H32N2O7Pureza:99.03% - 99.67%Forma y color:SolidPeso molecular:508.56Ergolide
CAS:Ergolide, from Inula Britannica, inhibits iNOS and COX-2 by deactivating NF-κB in macrophages.Fórmula:C17H22O5Pureza:99.64%Forma y color:SolidPeso molecular:306.35Ref: TM-T13686
1mg71,00€5mg139,00€1mL*10mM (DMSO)155,00€10mg230,00€25mg374,00€50mg520,00€100mg697,00€CAY10512
CAS:CAY10512, a resveratrol analog, is 100x more potent, inhibiting NF-κB with an IC50 of 0.15 μM versus resveratrol's 20 μM.Fórmula:C15H13FOForma y color:SolidPeso molecular:228.266IKKγ NBD Inhibitory Peptide
CAS:A cell-permeable synthetic peptide NEMO-binding domain peptide (NBD peptide) corresponding to the NEMO amino-terminal alpha-helical region is shown to block TNFFórmula:C170H259N49O42S1Pureza:98%Forma y color:SolidPeso molecular:3693.3
