PGE sintasa
La prostaglandina E sintasa (PGE sintasa) es una enzima involucrada en la biosíntesis de prostaglandina E2 (PGE2), un mediador lipídico que desempeña un papel clave en la inflamación, el dolor y la fiebre. La PGE2 está involucrada en varios procesos fisiológicos, incluidos las respuestas inmunitarias, la función vascular y la salud gastrointestinal. La desregulación de la producción de PGE2 está asociada con enfermedades inflamatorias, cáncer y trastornos cardiovasculares. En CymitQuimica, ofrecemos una selección de inhibidores y moduladores de PGE sintasa para apoyar su investigación en inflamación, manejo del dolor y patología de enfermedades.
Se han encontrado 31 productos de "PGE sintasa"
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hPGDS-IN-1
CAS:hPGDS-IN-1 is a hPGDS inhibitor.Fórmula:C22H20N6O3Pureza:99.77% - >99.99%Forma y color:SolidPeso molecular:416.43(S)-Flurbiprofen
CAS:Esflurbiprofen is an inhibitor of COX-1 and COX-2.Fórmula:C15H13FO2Pureza:99.99%Forma y color:White To Yellowish Crystalline PowderPeso molecular:244.26Dehydroevodiamine
CAS:Dehydroevodiamine (DHED), a constituent of Evodia rutaecarpa, has various biological effects such as hypotensive, negative chronotropic, ion channel depressantFórmula:C19H15N3OPureza:99.54%Forma y color:SolidPeso molecular:301.34CAFESTOL
CAS:Cafestol, an ERK inhibitor, suppresses PGE2 and COX-2 by blocking NF-kB in LPS-stimulated RAW264.7 cells.Fórmula:C20H28O3Pureza:97.06% - 99.08%Forma y color:SolidPeso molecular:316.43mPGES-1 Inhibitor-1
CAS:mPGES-1 Inhibitor-1 is an mPGES-1 inhibitor with anti-inflammatory and analgesic activity, which can be used to study acute liver injury.Fórmula:C16H19ClN4O2Pureza:96.84% - 98.75%Forma y color:SolidPeso molecular:334.8F092
CAS:F092 is a potent inhibitor of hematopoietic prostaglandin D synthetase (H-PGDS), which can be used to study allergic inflammation and vascular-related diseases.Fórmula:C20H17N5O2Pureza:99.63%Forma y color:SolidPeso molecular:359.38Friluglanstat
CAS:Friluglanstat is an inhibitor of the enzyme prostaglandin E synthase (mPGES-1) and exhibits anti-inflammatory activity [1].Fórmula:C25H20ClF3N4O3Pureza:98%Forma y color:SolidPeso molecular:516.9mPGES1-IN-3
CAS:mPGES1-IN-3 is a potent and selective inhibitor of microsomal prostaglandin E2 synthase-1 (mPGES-1) .Fórmula:C24H16ClF5N4O3Pureza:98%Forma y color:SolidPeso molecular:538.85mPGES1-IN-9
CAS:mPGES1-IN-9 (compound 1_8) is an mPGES1 inhibitor with an IC50 of 0.5 μM and is utilized in anti-inflammatory research.Fórmula:C25H18N4OSForma y color:SolidPeso molecular:422.502α-Gracinoic acid
CAS:α-Gracinoic acid acts as an inhibitor of mPGES-1, exhibiting anti-inflammatory properties.Fórmula:C29H42O4Forma y color:SolidPeso molecular:454.64PF-4693627
CAS:PF-4693627 is an effective and selective microsomal prostaglandin E synthase-1 inhibitor (IC50=3 nM).Fórmula:C26H29Cl2N3O3Pureza:98%Forma y color:SolidPeso molecular:502.43
