NOS
La óxido nítrico sintasa (NOS) es una enzima responsable de la producción de óxido nítrico (NO), una molécula de señalización involucrada en la vasodilatación, la neurotransmisión y las respuestas inmunitarias. Existen tres isoformas de NOS: neuronal (nNOS), endotelial (eNOS) e inducible (iNOS), cada una desempeñando roles distintos en procesos fisiológicos y patológicos. La desregulación de la actividad de NOS está implicada en enfermedades cardiovasculares, neurodegenerativas y condiciones inflamatorias. En CymitQuimica, ofrecemos una selección de moduladores de NOS para apoyar su investigación en biología vascular, neurobiología e inmunología.
Se han encontrado 62 productos de "NOS"
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Bendazol
CAS:<p>Bendazol (Dibazol) is always used as the drug for hypertension and cerebral Angiospasm.</p>Fórmula:C14H12N2Pureza:98.7% - 99.87%Forma y color:White Or Almost White Crystalline PowderPeso molecular:208.262-Thiouracil
CAS:2-Thiouracil (Deracil) is a thiolated uracil derivative that is a known anti-hyperthyroid agent.Fórmula:C4H4N2OSPureza:99.89%Forma y color:Minute Crystals Prisms Or White Or Pale Cream-Colored Powder White To Pale Yellow Crystalline PowderPeso molecular:128.15Chondroitin sulfate
CAS:<p>Chondroitin sulfate (Chonsurid) is extracted from shark bone;Store the product in sealed, cool and dry condition</p>Fórmula:(C14H21NO14S)nPureza:99.87%Forma y color:SolidPeso molecular:30,000-50,000S-Nitroso-N-acetyl-DL-penicillamine
CAS:S-Nitroso-N-acetyl-DL-penicillamine (SNAP) acts as a stable inhibitor of platelet aggregation, is a nitric oxide donor and .Fórmula:C7H12N2O4SPureza:97.42% - >99.99%Forma y color:Green Crystalline SolidPeso molecular:220.25Aminoguanidine hydrochloride
CAS:<p>Aminoguanidine hydrochloride (Hydrazinecarboximidamide) is a diamine oxidase and NO synthase inhibitor, used in the treatment of diabetic nephropathy.</p>Fórmula:CH6N4·HClPureza:99.80%Forma y color:White To Off-White SolidPeso molecular:110.55L-Arginine hydrochloride
CAS:L-Arginine hydrochloride is a nitrogen donor for synthesis of nitric oxide.Fórmula:C6H15ClN4O2Pureza:99.51%Forma y color:White Solid CrystallinePeso molecular:210.66Mifepristone
CAS:Mifepristone (C-1073) is a progesterone-receptor (IC50=0.2 nM) and glucocorticoid-receptor antagonist (IC50=2.6 nM). High-Quality, Low-Cost!Fórmula:C29H35NO2Pureza:98.9% - ≥95%Forma y color:Pale Yellow SolidPeso molecular:429.59Carboxyebselen
CAS:<p>Carboxyebselen (HOOC-Ebs) is an endothelial nitric oxide synthase (eNOS) inhibitor that is potent and selective.</p>Fórmula:C14H9NO3SePureza:98%Forma y color:SolidPeso molecular:318.192-Iminobiotin
CAS:2-Iminobiotin inhibits iNOS/nNOS; Ki: 21.8 μM (mouse iNOS), 37.5 μM (rat nNOS).Fórmula:C10H17N3O2SPureza:98%Forma y color:SolidPeso molecular:243.33NOS-IN-1
CAS:<p>NOS-IN-1: a potent oral NO synthase blocker, with IC50 of 0.1μM (iNOS), 0.2μM (nNOS), 1.1μM (eNOS).</p>Fórmula:C8H16N2O2Pureza:99.8%Forma y color:SolidPeso molecular:172.223-O-Acetyl-16α-hydroxydehydrotrametenolic acid
CAS:<p>3-O-Acetyl-16α-hydroxydehydrotrametenolic acid (3-O-Acetyl-16 alpha-hydroxydehydrotrametenolic acid) shows anti-inflammatory activity, it can inhibit NO</p>Fórmula:C32H48O5Pureza:98%Forma y color:SolidPeso molecular:512.72Epibetulinic acid
CAS:Epibetulinic acid reduces inflammation, suppressing NO and prostaglandin E2 in endotoxin-stimulated mouse macrophages.Fórmula:C30H48O3Pureza:99.66%Forma y color:SolidPeso molecular:456.7Isosorbide dinitrate
CAS:<p>Isosorbide dinitrate (Isordil) is a vasodilator used in the treatment of angina pectoris.</p>Fórmula:C6H8N2O8Pureza:99.87%Forma y color:Hard Colorless Crystals SolidPeso molecular:236.14Physalin L
CAS:Physalin L is a natural product,it shows a distinct fluorescence spot under UV 365 nm with good separation.Fórmula:C28H32O10Pureza:98%Forma y color:SolidPeso molecular:528.55Banoxantrone dihydrochloride
CAS:Banoxantrone dihydrochloride (AQ4N dihydrochloride) is a novel hypoxic cytotoxin that selectively kills hypoxic cells through an iNOS-dependent mechanism.Fórmula:C22H30Cl2N4O6Pureza:99.88%Forma y color:SolidPeso molecular:517.4Asperuloside
CAS:Asperuloside (Asperulosid) has anti-inflammatory activity.Fórmula:C18H22O11Pureza:99.42% - 99.99%Forma y color:SolidPeso molecular:414.36Asymmetric dimethylarginine
CAS:<p>Asymmetric dimethylarginine is an endogenous inhibitor of nitric oxide synthase (NOS)</p>Fórmula:C8H18N4O2Pureza:98% - 99.62%Forma y color:SolidPeso molecular:202.257-Nitroindazole
CAS:7-Nitroindazole is a non-selective inhibitor of NOS isoforms in vitro for neuronal nitric oxide synthase showing a 10-fold selectivity for neuronal NOS.Fórmula:C7H5N3O2Pureza:96.15% - 99.05%Forma y color:Orange-Yellow SolidPeso molecular:163.13Tryptanthrin
CAS:Tryptanthrin is a natural DNA gyrase inhibitor.Fórmula:C15H8N2O2Pureza:99.64% - 99.94%Forma y color:SolidPeso molecular:248.24Ethyl 3,4-dihydroxybenzoate
CAS:<p>Ethyl 3,4-dihydroxybenzoate (EDHB): a prolyl hydroxylase inhibitor attenuates acute hypobaric hypoxia mediated vascular leakage in brain.</p>Fórmula:C9H10O4Pureza:99.88%Forma y color:White Crystal Or PowderPeso molecular:182.17α-Humulene
CAS:α-Humulene (Alpha-caryophyllene) is extracted from S.officinalis essential oil.α-Humulene can inhibit tumor cell growth.α-Humulene also shows anti-inflammatoryFórmula:C15H24Pureza:97.18% - 97.18%Forma y color:LiquidPeso molecular:204.35Piceatannol 3'-O-glucoside
CAS:<p>Piceatannol 3'-O-glucoside (Piceatannol 3-glycoside) increases pulmonary blood oxygen tension and decreases pulmonary interstitial edema, so it can protect lung</p>Fórmula:C20H22O9Pureza:99.47% - 99.97%Forma y color:SolidPeso molecular:406.38S-Methylisothiourea sulfate
CAS:S-Methylisothiourea sulfate ((S)-Methylisothiourea sulfate) is a potent and selective inhibitor of iNOS and exerts beneficial effects in rodent models of septicFórmula:C2H6N2SH2O4SPureza:99.58%Forma y color:SolidPeso molecular:139.18Midostaurin
CAS:PKC412(Midostaurin (PKC412); CGP41231; CGP41251) is a broad spectrum protein kinase inhibitor.Fórmula:C35H30N4O4Pureza:97.61% - >99.99%Forma y color:SolidPeso molecular:570.64Avanafil
CAS:Avanafil (TA1790) is a selective inhibitor of phosphodiesterase type 5 (PDE5) and is used as therapy of erectile dysfunction.Fórmula:C23H26ClN7O3Pureza:99.03% - >99.99%Forma y color:White SolidPeso molecular:483.95Ginsenoside Rb3
CAS:Ginsenoside Rb3 (Gypenoside IV) is a natural triterpenoid saponin, exhibiting inhibition effect on TNFα-induced NF-κB transcriptional activity.Fórmula:C53H90O22Pureza:98% - 99.98%Forma y color:SolidPeso molecular:1079.27PRE-084 hydrochloride
CAS:PRE-084 hydrochloride is a selective agonist of σ1(IC50:44 nM, in the sigma receptor assay).Fórmula:C19H28ClNO3Pureza:99.54%Forma y color:SolidPeso molecular:353.886-Biopterin
CAS:<p>6-Biopterin (L-Biopterin) is a natural product,is a NO synthase cofactor.</p>Fórmula:C9H11N5O3Pureza:99.11%Forma y color:SolidPeso molecular:237.22Irisflorentin
CAS:Irisflorentin prevents cell death, boosts proteasomes via rpn-3, reduces egl-1, and lowers iNOS/NO in LPS-stimulated macrophages.Fórmula:C20H18O8Pureza:98.6% - 99.81%Forma y color:SolidPeso molecular:386.35Methylene Blue
CAS:Methylene Blue (Tetramethylthionine chloride) (IC50 of 1.9 μM) inhibits tau filament formation. And methylene Blue inhibits soluble guanylyl cyclase.Fórmula:C16H18ClN3SPureza:95.80%Forma y color:Dark Green Crystals Or Powder From Chloroform-Ethyl Ether Green Fine Crystalline PowderPeso molecular:319.85Pectolinarin
CAS:Pectolinarin is a Cirsium isolate with anti-inflammatory activity.Fórmula:C29H34O15Pureza:98% - 99.79%Forma y color:SolidPeso molecular:622.57L-Canavanine sulfate
CAS:L-Canavanine sulfate is a selective inducible NO synthase inhibitor.Fórmula:C5H14N4O7SPureza:99.73%Forma y color:SolidPeso molecular:274.25Agmatine sulfate
CAS:<p>Agmatine sulfate (Agmatine sulfate salt) is a bioactive metabolite of the arginine amino acid.</p>Fórmula:C5H16N4O4SPureza:99.56% - 99.86%Forma y color:White To Off-White PowderPeso molecular:228.27Regaloside B
CAS:<p>Regaloside B, a phenylpropanoid isolated from Lilium longiflorum, exhibits anti-inflammatory activity by inhibiting the expression of iNOS (inducible nitric</p>Fórmula:C20H26O11Pureza:99.4% - 99.57%Forma y color:SolidPeso molecular:442.41anemarsaponin B
CAS:<p>Anemarsaponin B has anti-inflammatory effect in LPS-treated RAW 264.7macrophages, the effect is associated with the inhibition of NF-κB transcriptional activity</p>Fórmula:C45H74O18Pureza:99.06% - 99.81%Forma y color:SolidPeso molecular:903.06Dehydroevodiamine
CAS:<p>Dehydroevodiamine (DHED), a constituent of Evodia rutaecarpa, has various biological effects such as hypotensive, negative chronotropic, ion channel depressant</p>Fórmula:C19H15N3OPureza:99.54%Forma y color:SolidPeso molecular:301.347-Ethoxyresorufin
CAS:<p>7-Ethoxyresorufin (Resorufin ethyl ether) (7-ER) is a fluorometric substrate for and competitive inhibitor of cytochrome P450, especially CYP1A1.</p>Fórmula:C14H11NO3Pureza:99.09% - 99.62%Forma y color:Red SolidPeso molecular:241.24L-Arginine
CAS:<p>L-Arginine (L-Arg) is a substrate of endothelial nitric oxide synthase (eNOS). High-Quality, Low-Cost!</p>Fórmula:C6H14N4O2Pureza:99.7% - 99.98%Forma y color:Solid CrystallinePeso molecular:174.2Prim-O-glucosylcimifugin
CAS:Prim-O-glucosylcimifugin (Cimifugin 7-glucoside) can inhibit the proliferation of SMC stimulated by TNF-alpha, increase the proportion of G0/G1 phase.Fórmula:C22H28O11Pureza:98.57% - 99.92%Forma y color:SolidPeso molecular:468.45Methylene Blue trihydrate
CAS:<p>Dark green, bronze-lustered Methylene Blue trihydrate is a deep blue dye in water/alcohol, used in staining, cyanide treatment, and methemoglobin reduction.</p>Fórmula:C16H24ClN3O3SPureza:95.42% - 99.6%Forma y color:Dark Green SolidPeso molecular:373.91400W dihydrochloride
CAS:1400W dihydrochloride (N-(3-(Aminomethyl)benzyl)acetamidine) is a highly effective and specific inhibitor of inducible NOS2 (iNOS).Fórmula:C10H17Cl2N3Pureza:98% - 99.94%Forma y color:SolidPeso molecular:250.17N'-Nitro-D-arginine
CAS:<p>N'-Nitro-D-arginine (N'-Nitro-D-arginine) is a Building Block.</p>Fórmula:C6H13N5O4Pureza:99.81%Forma y color:White To Off White PowderPeso molecular:219.2Dimaprit dihydrochloride
CAS:Dimaprit dihydrochloride: selective H2 agonist, inhibits nNOS (IC50: 49 μM), boosts gastric acid.Fórmula:C6H15N3S·2HClPureza:99.79%Forma y color:SolidPeso molecular:234.19ETHYL CAFFEATE
CAS:Ethyl Caffeate (ETHYL 3,4-DIHYDROXYCINNAMATE) suppressed the differentiation of naive CD4+ T cells into Th1 in vitro.Fórmula:C11H12O4Pureza:97.79%Forma y color:SolidPeso molecular:208.21Harpagoside
CAS:Harpagoside: anti-inflammatory; 3 mM inhibits seed germination; reduces COX-2, iNOS mRNA, and protein in HepG2.Fórmula:C24H30O11Pureza:99.71% - ≥95%Forma y color:White To Off-White PowderPeso molecular:494.49TRIM
CAS:TRIM (1-(2-Trifluoromethylphenyl)imidazole) is an inhibitor of nNOS.Fórmula:C10H7F3N2Pureza:98.98%Forma y color:White SolidPeso molecular:212.172-Iminobiotin hydrobromide
CAS:<p>2-Iminobiotin hydrobromide (Guanidinobiotin) is a cyclic guanidino analog of biotin that acts as a reversible inhibitor of inducible nitric oxide synthase (iNOS</p>Fórmula:C10H18BrN3O2SPureza:98.13%Forma y color:SolidPeso molecular:324.24Ginsenoside C-K
CAS:<p>Ginsenoside C-K (Ginsenoside K) is a bacterial metabolite of G-Rb1 exhibiting anti-inflammatory effects by reducing iNOS and COX-2.</p>Fórmula:C36H62O8Pureza:99.65% - 99.97%Forma y color:SolidPeso molecular:622.87Crocin II
CAS:Crocin II combats gastric and liver injuries, reduces inflammation, apoptosis, oxidative stress, and may lower lipid levels and have antidepressant effects.Fórmula:C38H54O19Pureza:98% - 99.00%Forma y color:SolidPeso molecular:814.822,4-Diamino-6-hydroxypyrimidine
CAS:2,4-Diamino-6-hydroxypyrimidine (DAHP) (DAHP) is a selective, specific inhibitor of GTP cyclohydrolase I, the rate limiting step for de novo pterin synthesisFórmula:C4H6N4OPureza:99.82%Forma y color:White Solid CrystalsPeso molecular:126.12L-NAME hydrochloride
CAS:L-NAME hydrochloride (L-NAME HCl), a cell-permeable NO synthase inhibitor, displays Ki values of 4.4 μM, 15 nM, and 39 nM, for iNOS (mouse) , nNOS (bovine) ,Fórmula:C7H15N5O4·HClPureza:98.71% - 99.93%Forma y color:White To Off-White PowderPeso molecular:269.69Madecassic acid
CAS:Madecassic acid (L-fucopyranose) is extracted from the whole herb of Centella asiatica.Fórmula:C30H48O6Pureza:98.80% - 99.69%Forma y color:SolidPeso molecular:504.70Cistanoside A
CAS:Cistanoside A protects mice from CCl4-induced liver damage by enhancing radical clearance, reducing lipid peroxidation, and boosting mitochondrial function.Fórmula:C36H48O20Pureza:98.24% - 99.86%Forma y color:SolidPeso molecular:800.75EIT hydrobromide
CAS:EIT hydrobromide (S-Ethylisothiourea hydrobromide) is an iNOS inhibitor.Fórmula:C3H9BrN2SPureza:99.81%Forma y color:White Crystalline SolidPeso molecular:185.093,4-DAA
CAS:3,4-DAA has anti-inflammatory activity and inhibits EOC20 cell-induced nitric oxide synthase (iNOS) induced by IFN-γ and lipopolysaccharide.Fórmula:C18H17NO6Pureza:98%Forma y color:SolidPeso molecular:343.33L-NMMA acetate
CAS:L-NMMA acetate inhibits all NOS types (nNOS, eNOS, iNOS); Ki: 0.18, 0.4, 6 µM respectively.Fórmula:C9H20N4O4Pureza:99.72% - 99.8%Forma y color:White To Off-White SolidPeso molecular:248.28AVE-9488
CAS:<p>AVE-9488 is a novel endothelial NO synthase (eNOS) enhancer that upregulates eNOS expression, induces NO production, and may ameliorate portal hypertension.</p>Fórmula:C16H14FNOPureza:99.87%Forma y color:SolidPeso molecular:255.293-Bromo-7-nitroindazole
CAS:3-Bromo-7-nitroindazole specifically inhibits nNOS, impacting NO synthesis in brain/body.Fórmula:C7H4BrN3O2Pureza:98.2%Forma y color:Yellowish SolidPeso molecular:242.03Kuwanon A
CAS:Kuwanon A inhibits nitric oxide production (IC50: 10.5 μM). Kuwanon A is a flavone derivative isolated from Morus alba L.Fórmula:C25H24O6Pureza:99.96%Forma y color:SolidPeso molecular:420.45Celiprolol hydrochloride
CAS:Celiprolol hydrochloride (Selectrol) is a cardioselective beta-1 adrenergic antagonist that has intrinsic sympathomimetic activity.Fórmula:C20H33N3O4·HClForma y color:White Crystalline SolidPeso molecular:415.96Dimethoxycurcumin
CAS:Dimethoxycurcumin is a stable curcumin analog causing epigenetic shifts in leukemia cells, affecting gene expression.Fórmula:C23H24O6Pureza:99.87%Forma y color:SolidPeso molecular:396.43
