NOS
La óxido nítrico sintasa (NOS) es una enzima responsable de la producción de óxido nítrico (NO), una molécula de señalización involucrada en la vasodilatación, la neurotransmisión y las respuestas inmunitarias. Existen tres isoformas de NOS: neuronal (nNOS), endotelial (eNOS) e inducible (iNOS), cada una desempeñando roles distintos en procesos fisiológicos y patológicos. La desregulación de la actividad de NOS está implicada en enfermedades cardiovasculares, neurodegenerativas y condiciones inflamatorias. En CymitQuimica, ofrecemos una selección de moduladores de NOS para apoyar su investigación en biología vascular, neurobiología e inmunología.
Se han encontrado 61 productos de "NOS"
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1400W dihydrochloride
CAS:1400W dihydrochloride (N-(3-(Aminomethyl)benzyl)acetamidine) is a highly effective and specific inhibitor of inducible NOS2 (iNOS).Fórmula:C10H17Cl2N3Pureza:98% - 99.94%Forma y color:SolidPeso molecular:250.17N'-Nitro-D-arginine
CAS:<p>N'-Nitro-D-arginine (N'-Nitro-D-arginine) is a Building Block.</p>Fórmula:C6H13N5O4Pureza:99.81%Forma y color:White To Off White PowderPeso molecular:219.2Dimaprit dihydrochloride
CAS:Dimaprit dihydrochloride: selective H2 agonist, inhibits nNOS (IC50: 49 μM), boosts gastric acid.Fórmula:C6H15N3S·2HClPureza:99.79%Forma y color:SolidPeso molecular:234.19ETHYL CAFFEATE
CAS:Ethyl Caffeate (ETHYL 3,4-DIHYDROXYCINNAMATE) suppressed the differentiation of naive CD4+ T cells into Th1 in vitro.Fórmula:C11H12O4Pureza:97.79%Forma y color:SolidPeso molecular:208.21Harpagoside
CAS:Harpagoside: anti-inflammatory; 3 mM inhibits seed germination; reduces COX-2, iNOS mRNA, and protein in HepG2.Fórmula:C24H30O11Pureza:99.71% - ≥95%Forma y color:White To Off-White PowderPeso molecular:494.492-Iminobiotin hydrobromide
CAS:<p>2-Iminobiotin hydrobromide (Guanidinobiotin) is a cyclic guanidino analog of biotin that acts as a reversible inhibitor of inducible nitric oxide synthase (iNOS</p>Fórmula:C10H18BrN3O2SPureza:98.13%Forma y color:SolidPeso molecular:324.24Ginsenoside C-K
CAS:<p>Ginsenoside C-K (Ginsenoside K) is a bacterial metabolite of G-Rb1 exhibiting anti-inflammatory effects by reducing iNOS and COX-2.</p>Fórmula:C36H62O8Pureza:99.65% - 99.97%Forma y color:SolidPeso molecular:622.87Crocin II
CAS:Crocin II combats gastric and liver injuries, reduces inflammation, apoptosis, oxidative stress, and may lower lipid levels and have antidepressant effects.Fórmula:C38H54O19Pureza:98% - 99.00%Forma y color:SolidPeso molecular:814.822,4-Diamino-6-hydroxypyrimidine
CAS:2,4-Diamino-6-hydroxypyrimidine (DAHP) (DAHP) is a selective, specific inhibitor of GTP cyclohydrolase I, the rate limiting step for de novo pterin synthesisFórmula:C4H6N4OPureza:99.82%Forma y color:White Solid CrystalsPeso molecular:126.12L-NAME hydrochloride
CAS:L-NAME hydrochloride (L-NAME HCl), a cell-permeable NO synthase inhibitor, displays Ki values of 4.4 μM, 15 nM, and 39 nM, for iNOS (mouse) , nNOS (bovine) ,Fórmula:C7H15N5O4·HClPureza:98.71% - 99.93%Forma y color:White To Off-White PowderPeso molecular:269.69Madecassic acid
CAS:Madecassic acid (L-fucopyranose) is extracted from the whole herb of Centella asiatica.Fórmula:C30H48O6Pureza:98.80% - 99.69%Forma y color:SolidPeso molecular:504.70Cistanoside A
CAS:Cistanoside A protects mice from CCl4-induced liver damage by enhancing radical clearance, reducing lipid peroxidation, and boosting mitochondrial function.Fórmula:C36H48O20Pureza:98.24% - 99.86%Forma y color:SolidPeso molecular:800.75TRIM
CAS:TRIM (1-(2-Trifluoromethylphenyl)imidazole) is an inhibitor of nNOS.Fórmula:C10H7F3N2Pureza:98.98%Forma y color:White SolidPeso molecular:212.17EIT hydrobromide
CAS:EIT hydrobromide (S-Ethylisothiourea hydrobromide) is an iNOS inhibitor.Fórmula:C3H9BrN2SPureza:99.81%Forma y color:White Crystalline SolidPeso molecular:185.093,4-DAA
CAS:3,4-DAA has anti-inflammatory activity and inhibits EOC20 cell-induced nitric oxide synthase (iNOS) induced by IFN-γ and lipopolysaccharide.Fórmula:C18H17NO6Pureza:98%Forma y color:SolidPeso molecular:343.33L-NMMA acetate
CAS:L-NMMA acetate inhibits all NOS types (nNOS, eNOS, iNOS); Ki: 0.18, 0.4, 6 µM respectively.Fórmula:C9H20N4O4Pureza:99.72% - 99.8%Forma y color:White To Off-White SolidPeso molecular:248.283-Bromo-7-nitroindazole
CAS:3-Bromo-7-nitroindazole specifically inhibits nNOS, impacting NO synthesis in brain/body.Fórmula:C7H4BrN3O2Pureza:98.2%Forma y color:Yellowish SolidPeso molecular:242.03Kuwanon A
CAS:Kuwanon A inhibits nitric oxide production (IC50: 10.5 μM). Kuwanon A is a flavone derivative isolated from Morus alba L.Fórmula:C25H24O6Pureza:99.96%Forma y color:SolidPeso molecular:420.45Celiprolol hydrochloride
CAS:Celiprolol hydrochloride (Selectrol) is a cardioselective beta-1 adrenergic antagonist that has intrinsic sympathomimetic activity.Fórmula:C20H33N3O4·HClForma y color:White Crystalline SolidPeso molecular:415.96
