CXCR

Tannic acid is a novel hERG channel blocker.

Motixafortide (BKT140 4-fluorobenzoyl) is an antagonist of CXCR4 (IC50: 1 nM).

VUF11207 fumarate is an agonist of CXCR7 and a high-potency ligand of CXCR7 (pKi: 8.1).

AMG 487 is a potent and selective antagonist of chemokine (C-X-C motif) receptor 3 (CXCR3) …

Ly2510924 acetate is an potent and selective CXCR4 antagonist. It prevents the binding of SDF-1 …

ATI-2341, pepducin targeting the C-X-C chemokine receptor type 4 (CXCR4), is an allosteric agonist activating …

Reparixin L-lysine salt is an allosteric chemokine receptor 1/2 (CXCR1/2) activation inhibitor.

Motixafortide is an antagonist of CXCR4 with IC50 of ～1 nM. It induces the apoptosis …

IT1t dihydrochloride inhibits CXCL12/CXCR4 interaction with IC50 of 2.1 nM. IT1t dihydrochloride is an antagonist …

rac-NBI-74330 is an effective and selective CXCR3 antagonist.

Elubrixin inhibits neutrophil CD11b upregulation (IC50 of 260.7 nM) and shape change (IC50 of 310.5 …

Balixafortide TFA (POL6326 TFA) is a selective, well-tolerated peptidic CXCR4 antagonist (IC50 < 10 nM). It …

Balixafortide (POL6326) is a potent, selective, well-tolerated peptidic CXCR4 antagonist with an IC50 < 10 nM …

Vestitol has antioxidation, anti-inflammatory and antimicrobial activities, it can strongly act in a low dose …

ALX 40-4C acetate is a CXCR4 inhibitor of the chemokine receptor (Ki = 1 μM) …

CXCR2-IN-1 has a pIC50 of 9.3 and is a CXCR2 antagonist of the central nervous …

Mavorixafor is an effective and selective antagonist of CXCR4, with an IC50 value of 13 …

ITIC has a superior thermal stability and undergoes a glass-crystal transition considerably below its high …

NUCC-390 dihydrochloride is selective agonist of small-molecule CXCR4 receptor.

NUCC-390 is a novel and selective small-molecule CXCR4 receptor agonist. NUCC-390 induces internalization of CXCR4 …

ITIC-4F has broad applicability in high-efficiency binary and ternary single-junction as well as tandem polymer …

TC14012 acetate is a serum-stable derivative of T140 which is a selective and peptidomimetic CXCR4 …

Danirixin is a potent antagonist of CXCR2 that inhibits IL-8 binding to CXCR2 (IC50: 12.5 …

ATI-2341 acetate is an effective allosteric agonist of CXCR4, it activates Gα1 instead of Gα13. …

Nicotinamide N-oxide is recognized as an in vivo metabolite of nicotinamide which is a precurser …

TAK-779 is an antagonist of chemokine receptor 5 (CCR5), CCR2b, and CXC chemokine receptor 3 …

AZD-5069 is an chemokine receptor 2 antagonist (CXCR2; IC50 = 0.79 nM).

Baohuoside I is a component of Epimedium koreanum, exhibits anti-inflammatory activity and anti-osteoporosis activities.

CTCE 9908 acetate is an antagonist of CXCR4 and inhibits migration in CXCR4-expressing ovarian cancer …

1. Decursin is able to attenuate kainic acid-induced seizures and could have potential as an …

SB-265610 is a nonpeptide and allosteric CXCR2 antagonist. SB-265610 blocks rat cytokine-induced neutrophil chemoattractant-1 (CINC-1)-induced …

Reparixin is a potent inhibitor of both CXCL8 receptors CXCR1/2, it inhibits weakly CXCR2-mediated cell …

MSX-130 is CXCR4 Antagonist.

LIT-927 is an orally active CXCL12 neutraligand (Ki: 267 nM for CXCL12 binding to CXCR4).

AMD 3100 octahydrochloride blocks the binding of stromal cell-derived factor (SDF-1alpha) to the cellular receptor …

SB225002 is a potent and selective CXCR2 antagonist inhibiting interleukin IL-8 binding to CXCR2.

UNBS-5162 is a novel naphthalimide that decreases CXCL chemokine expression in experimental prostate cancers.

SX-682 is a potent, selective and orally bioavailable inhibitor of CXCR1/2 ,has the potential to …

JMS-17-2 is a potent and selective antagonist of CX3CR1( IC50 : 0.32 nM).

WZ811 is a novel and effective small molecular CXCR4 antagonist (EC50: 0.3 nM).

MSX-122 is a novel small molecule and partial CXCR4 antagonist, with potent inhibition of CXCR4/CXCL12 …

FC131 TFA is an antagonist of CXCR4 that inhibits the binding of [125I] -sdf-1 to …

AMD 3465 hexahydrobromide is a CXCR4 receptor antagonist with potential anticancer and anti-HIV activity.

ML339 a selective inhibitor of CXCR6(IC50 = 140 nM) with no response when screened against …

SRT3109 is a CXCR2 ligand used in the treatment of chemokine mediated diseases and conditions.

AMD-070 hydrochloride is a CXCR4 antagonist, is useful for Anti HIV.

Navarixin(SCH527123) is a novel, selective CXC chemokine receptor 2(CXCR2) antagonist that inhibits neutrophil activation and …

MSX-127 elicites positive response in peptide CXCR4.

Arteether is a new, fast-acting antimalarial drug.

Plerixafor, a chemokine receptor antagonist, blocks the binding of stromal cell-derived factor (SDF-1alpha) to the …

USL311 is a CXCR4 receptor antagonist which prevents the binding of stromal-cell derived factor-1 (SDF-1 …

SRT3190 is an antagonist of CXCR2.

E6130 may be effective in the treatment of inflammatory bowel disease and is a highly …

Burixafor hydrobromide (TG-0054 hydrobromide) is an orally bioavailable and potent CXCR4 antagonist and an anti-angiogenic …

SCH 563705 is an effective and orally available CXCR2 and CXCR1 antagonist (IC50s: 1.3 nM, …