NOD
Las proteínas NOD son receptores intracelulares que reconocen componentes microbianos y desempeñan un papel crítico en la respuesta inmune innata al activar vías de señalización inflamatorias, incluido NF-κB. Los receptores NOD están involucrados en la detección de infecciones bacterianas y están asociados con la patogénesis de enfermedades inflamatorias intestinales, trastornos autoinmunes e inflamación crónica. En CymitQuimica, ofrecemos una variedad de moduladores de la vía NOD de alta calidad para apoyar su investigación en inmunidad innata, inflamación y salud gastrointestinal.
Se han encontrado 24 productos de "NOD"
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
BAL-0028
CAS:BAL-0028 is a potent inhibitor of NLRP3 activation (IC50: 25 nM) with anti-inflammatory activity for cancer research.
Fórmula:C24H22FN3O2Pureza:99.16%Forma y color:SoildPeso molecular:403.45Dapansutrile
CAS:Dapansutrile is a potent, selective and orally active NLRP3 inflammasome inhibitor, with Anti-inflammatory and analgesic activity.Fórmula:C4H7NO2SPureza:≥98% - ≥98%Forma y color:SolidPeso molecular:133.17Ref: TM-T15052
5mg46,00€10mg66,00€25mg123,00€50mg205,00€100mg334,00€200mg394,00€1mL*10mM (DMSO)49,00€NT-0249
CAS:NT-0249 is an inflammatory vesicle NLRP3 inhibitor with anti-inflammatory activity that reverses high-fat diet-induced obesity.Fórmula:C22H28N5NaO4SPureza:98.11%Forma y color:SoildPeso molecular:481.54Diisononyl phthalate
CAS:Diisononyl phthalate (DINP), a phthalate, a plasticizer, activates the ACE/AT1R axis and inhibits NO production, inducing elevated blood pressure in mice.Fórmula:C26H42O4Pureza:99.97%Forma y color:Colorless Liquid In Water (Uscg 1999)Peso molecular:418.61LL-37 GKE acetate
LL-37 GKE acetate, a peptide and active structural domain of LL-37, inhibits lps-induced vascular nitric oxide production,less toxic,antimicrobial，sepsis.Fórmula:C121H206N38O30Pureza:99.88%Forma y color:SolidPeso molecular:2673.17NP3-146
CAS:NP3-146 (NLRP3-IN-5) is an inflammasome NLRP3 inhibitor with potential anti-inflammatory activity for the study of autoimmune diseases.
Fórmula:C20H27ClN2O5SPureza:99.21%Forma y color:SolidPeso molecular:442.96MCC950
CAS:MCC950 (CP-456773) is a NLRP3 inflammasome inhibitor (IC50=7.5-8.1 nM). MCC950 can be used to treat inflammatory diseases. High-Quality, Low-Cost!Fórmula:C20H24N2O5SPureza:97% - 98%Forma y color:SolidPeso molecular:404.48BMS986299
CAS:BMS986299 is a modulator of NLRP3 with an EC50 of 1.28 μM and can be used in studies about NLRP3 signaling and the treatment of associated diseases.Fórmula:C18H19N7OPureza:99.93% - 99.93%Forma y color:SolidPeso molecular:349.39Muramyl dipeptide
CAS:MDP is a synthetic peptide promoting bone formation by modulating osteoclasts, osteoblasts, and Runx2 expression via MAPK pathways.Fórmula:C19H32N4O11Pureza:99.34%Forma y color:SolidPeso molecular:492.48CY-09
CAS:CY-09 is an NLRP3 inhibitor.Fórmula:C19H12F3NO3S2Pureza:99.25% - >99.99%Forma y color:SolidPeso molecular:423.43Nodinitib-1
CAS:Nodinitib-1 (CID-1088438) is a potent and selective NOD1 inhibitor with an IC50 of 0.56 μM.Fórmula:C14H13N3O2SPureza:99.97% - >99.99%Forma y color:SolidPeso molecular:287.34NLRP3-IN-2
CAS:NLRP3-IN-2 (5-Chloro-N-(p-sulfamoylphenethyl)-o-anisamide), an intermediate capable of synthesizing glibenclamide.Fórmula:C16H17ClN2O4SPureza:98.98%Forma y color:Light Yellow SolidPeso molecular:368.84NOD-IN-1
CAS:NOD-IN-1 (Compound 4) is a potent mixed inhibitor of nucleotide-binding oligomerization domain (NOD)-like receptors.Fórmula:C18H17NO4SPureza:99.93% - >99.99%Forma y color:SolidPeso molecular:343.4INF39
CAS:INF39 is a noncytotoxic and irreversible NLRP3 inhibitor.Fórmula:C12H13ClO2Pureza:99.5% - 99.78%Forma y color:SolidPeso molecular:224.68NLRP3-IN-11
CAS:NLRP3-IN-11 is an NLRP3 protein inhibitor with potential anti-inflammatory activity.NLRP3-IN-11 can be used in the study of atherosclerosis and parkinsonism.Fórmula:C17H17ClN4O2Pureza:>99.99%Forma y color:SolidPeso molecular:344.8AZD4144
CAS:AZD4144 is a potent and selective NLRP3 inhibitor (IC50 = 54 nM) that reducs IL-1β and IL-18 production for immune disorders.Fórmula:C18H16F3N3O3Pureza:99.02%Forma y color:SoildPeso molecular:379.33Emlenoflast sodium
CAS:Emlenoflast sodium (MCC7840 sodium), a sulfonylurea, is a selective NLRP3 inflammasome inhibitor with an IC50 value of less than 100 nM for NLRP3 inflammasome,Fórmula:C19H24N4NaO3SForma y color:SolidPeso molecular:411.47NLRP3-IN-13
CAS:NLRP3-IN-13 is an NLRP3 inhibitor that inhibits NLRP3-associated inflammation.NLRP3-IN-13 can be used in the study of neurological disorders and inflammation.Fórmula:C19H15N3O3SPureza:99.16%Forma y color:SolidPeso molecular:365.41Emlenoflast
CAS:Emlenoflast (MCC7840) is a selective inhibitor of NLRP3 inflammasome.Fórmula:C19H24N4O3SPureza:97.004% - 98.19%Forma y color:SolidPeso molecular:388.48JC124
CAS:JC124 is an inhibitor of NLRP3 Inflammasome and exhibits neuroprotective and anti-inflammatory activities.Fórmula:C17H19ClN2O4SPureza:99.64%Forma y color:SolidPeso molecular:382.86Ref: TM-T25548
1mg60,00€5mg138,00€10mg215,00€25mg359,00€50mg510,00€100mg692,00€200mg888,00€1mL*10mM (DMSO)152,00€NLRP3-IN-10
CAS:NLRP3-IN-10 (ZVN26391) is a strong NLRP3 inhibitor, IC50 251.1 nM, that reduces IL-1β and ASC speck, hindering inflammasome activation.Fórmula:C17H14BrFO3Pureza:99.06%Forma y color:SolidPeso molecular:365.19Ref: TM-T61392
5mg44,00€10mg66,00€25mg119,00€50mg177,00€100mg295,00€200mg440,00€1mL*10mM (DMSO)62,00€NLRP3-IN-9
CAS:NLRP3-IN-9 (INF-4E) irreversibly inhibits NLRP3 ATPase, caspase-1, and prevents pyroptosis in THP-1 cells.Fórmula:C12H13ClO3Pureza:99.64%Forma y color:SolidPeso molecular:240.68Usnoflast
CAS:Usnoflast (ZYIL1) is an NLRP3 inhibitor, inhibiting NLRP3 inflammasome activation, used in neurological disease research.Fórmula:C21H29N3O3SPureza:98.79%Forma y color:SolidPeso molecular:403.54NOD1/2 antagonist-1
CAS:NOD1/2 antagonist-1 inhibits NOD1 (IC50 1.13 μM) and NOD2 (IC50 0.77 μM), enhances paclitaxel antitumor efficacy and is used to study innate immune signaling.Fórmula:C32H28ClF5N4O4Pureza:99.69%Forma y color:SolidPeso molecular:663.03
