NADPH-oxidasa

Ketoconazole, a CYP3A4 inhibitor, is an imidazole anti-fungal agent.

Cistanoside F shows vasorelaxant, and antioxidative effects, it shows a strong free radical scavenging activity …

2'-Hydroxygenistein is an isoflavonoid phytoalexin, it suppresses chemical mediators in inflammatory cells, may have value …

Flavokawain C is a melanogenesis inhibitor, it inhibited melanogenesis with IC50 values of 6.9 μM. …

Isopedicin has anti-inflammatory functions, it inhibits the O(2)(*)(-) production in human neutrophils by an elevation …

Phox-I2 is an NOX2-specific inhibitor. Phox-I2 reverts ROS-accumulation and leads to refusion of mitochondrial networks.

2-Amino-3-carboxy-1,4-naphthoquinone is the electron transfer mediator, can change glucose metabolism of the homofermentative lactic acid …

Paeonilactone B is a natural product from Paeonia albiflora.

Pisatin is an isoflavonoid phytoalexin synthesized by pea (Pisum sativum L.).

Chalepensin behaves as an energy transfer inhibitor at low concentration, it inhibits multiple P450s and …

Horminone has antimicrobial activity, it can inhibit the protein synthesis in several types of bacteria; …

8alpha-(2-Methylacryloyloxy)hirsutinolide 13-O-acetate shows inhibitory activity toward CYP2A6 and MAO-A and MAO-B enzymes.

Aucuparin is a plant antibiotic with anti-inflammatory activity. Aucuparin inhibited pulmonary fibrosis in mouse models …

5'-Demethylaquillochin and its isomer from the dichloromethane extract of E. cavaleriei have potential as chemopreventive …

gp91ds-tat是一种NADPH氧化酶(NADPH oxidase)的肽抑制剂,由与人类免疫缺陷病毒-tat肽相连的gp91phox序列组成。tat序列促进了这种肽进入细胞。

4 beta-Carboxy-19-nortotarol can inhibit microsomal lipid peroxidation induced by Fe(III)-ADP/NADPH and mitochondrial lipid peroxidation induced …

Totaradiol shows antioxidant activity, it can inhibit linoleic acid autoxidation but not generation of superoxide …

8alpha-Tigloyloxyhirsutinolide 13-O-acetate shows inhibitory activity toward CYP2A6 and MAO-A and MAO-B enzymes. 8alpha-Tigloyloxyhirsutinolide 13-O-acetate has …

Rehmannic acid and oleanolic acetate inhibit succinoxidase activity. Both Rehmannic acid and Icterogenin are potent …

Neoechinulin A has anti-inflammatory effect against LPS-stimulated RAW264.7 macrophages through inhibition of the NF-κB and …

Vitexilactone is a HIV-1 reverse transcriptase inhibitor in virtual screening against Indonesian Herbal Database using …

Zederone has anti-bacterial activity,it inhibits gram-positive bacteria activity. Zederone induces hepatotoxicity implicated the induction of …

(R)-Reticuline is the biosynthetic precursor of the morphinan alkaloids.

Cycloheterophyllin has an antioxidant effect, it is a photoprotective agent that inhibits ultraviolet A (UVA)-induced …

Sprengerinin C exerts anti-tumorigenic effects in hepatocellular carcinoma via inhibition of proliferation and angiogenesis and …

APX-115 (Ewha-18278) is a potent, orally active pan NADPH oxidase (Nox) inhibitor (Kis: 1.08 μM, …

Quercetin-3-O-glucose-6''-acetate is an inhibitor of NADPH oxidase. Quercetin-3-O-glucose-6''-acetate has antioxidant activities.

NoxA1ds acetate is a potent and selective NADPH oxidase 1 (NOX1) inhibitor (IC50 : 20 …

5-Heneicosylresorcinol shows inhibitory effects on the release of β-hexosaminidase from RBL-2H3 cells, it also prevents …

Protosappanin A has anti-oxidative/nitrative activities on brain immune and neuroinflammation through regulation of CD14/TLR4-dependent IKK/IκB/NF-κB …

NecroX-7 is a potent free radical scavenger and a HMGB1 (high-mobility group box 1) inhibitor. …

Sappanone A is the first homoisoflavanone to be discovered with melanogenesis inhibitory activity. It exerts …