Receptor de IL
Los receptores de interleucina (receptores IL) son un grupo de receptores que se unen a las interleucinas, una familia de citocinas que desempeñan roles esenciales en la regulación del sistema inmunológico, la inflamación y la hematopoyesis. La desregulación de la señalización de interleucinas está asociada con diversas enfermedades inflamatorias y autoinmunes, lo que convierte a los receptores IL en objetivos críticos para la intervención terapéutica. Se están explorando los antagonistas de los receptores IL para el tratamiento de afecciones como la artritis reumatoide, la psoriasis y las enfermedades inflamatorias intestinales. En CymitQuimica, ofrecemos una gama de moduladores de receptores IL de alta calidad para apoyar su investigación en señalización de citocinas, inmunología y terapia de enfermedades inflamatorias.
Se han encontrado 112 productos de "Receptor de IL"
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CP 424174
CAS:<p>CP 424174 blocks IL-1β processing (IC50: 210 nM), halts mature IL-1β formation, limits NLRP3, and is effective orally in vivo.</p>Fórmula:C22H29ClN2O4SPureza:>99.99%Forma y color:SolidPeso molecular:452.99Suplatast (Tosilate)
CAS:<p>Suplatast Tosilate (IPD 1151T) is a novel capsular anti-asthmatic drug. It ( IC50 above 100 μM) inhibits both IgE production, IL-4 and IL-5 synthesis.</p>Fórmula:C23H33NO7S2Pureza:99.34% - 99.65%Forma y color:White Or Off-White CrystalsPeso molecular:499.64Esonarimod
CAS:<p>Esonarimod (KE-298) is an antirheumatic drug.</p>Fórmula:C14H16O4SPureza:97.44%Forma y color:SolidPeso molecular:280.34GIBH-130
CAS:<p>GIBH-130 markedly inhibits the IL-1β secretion by activated microglia (IC50: 3.4 nM). GIBH-130 is an effective inhibitor of neuroinflammation.</p>Fórmula:C20H20N6OPureza:99.52%Forma y color:SolidPeso molecular:360.41GSK717
CAS:<p>GSK717: potent, selective NOD2 inhibitor; disrupts NOD2/TLR2 synergy; no effect on NOD1, TNFR1, TLR2.</p>Fórmula:C28H28N4O2Pureza:97.34% - 99.01%Forma y color:SolidPeso molecular:452.55VGX-1027
CAS:<p>VGX-1027 (GIT 27) is an isoxazole compound with various immunomodulatory properties.</p>Fórmula:C11H11NO3Pureza:99.54% - 99.86%Forma y color:SolidPeso molecular:205.21Secukinumab
CAS:<p>Secukinumab is a fully humanized monoclonal anti-IL-17A antibody and the first in its class to be approved by the US Food and Drug Administration for the</p>Pureza:97.4% (SDS-PAGE); 98.3% (SEC-HPLC) - 99.10%Forma y color:LiquidPeso molecular:147.93 kDaYM-90709
CAS:<p>YM-90709 is a new-type antagonist inhibiting the binding of interleukin-5 to the interleukin-5 receptor.</p>Fórmula:C22H21N3O2Pureza:>99.99%Forma y color:SolidPeso molecular:359.42AX-024 hydrochloride
CAS:<p>AX-024 hydrochloride (AX-024 HCl) is an cytokine release inhibitor which can strongly inhibit the production of IL-6, TNFα, IFN-γ, IL-10 and IL-17A.</p>Fórmula:C21H23ClFNO2Pureza:99.74%Forma y color:SolidPeso molecular:375.87Apilimod 2HCl
CAS:<p>Apilimod 2HCl (STA 5326 2HCl) is a PIKFYVE kinase inhibitor used in the study of amyotrophic lateral sclerosis.</p>Fórmula:C23H28Cl2N6O2Pureza:98.41%Forma y color:SolidPeso molecular:491.41Clodronate disodium tetrahydrate
CAS:<p>Clodronate disodium tetrahydrate (Clastoban) inhibits bone resorption and soft tissue calcification.</p>Fórmula:CH10Cl2Na2O10P2Pureza:98%Forma y color:SolidPeso molecular:360.92Satralizumab
CAS:<p>Satralizumab (SA-237) is a humanized antibody targeting interleukin-6 (IL-6), used in research on neuromyelitis optica spectrum disorder (NMOSD).</p>Pureza:95%Forma y color:LiquidSirukumab
CAS:<p>Sirukumab (CNTO-136) is a humanized monoclonal antibody binding to IL-6, inhibiting IL-6-mediated signaling and transcription activator activation.</p>Pureza:>95%Forma y color:LiquidPeso molecular:144.6 (kDa)Brazikumab
CAS:<p>Brazikumab (AMG 139) is a humanized antibody targeting IL-23 by binding to the P19 subunit, a selective IL-23p19 antagonist.</p>Pureza:98% (SDS-PAGE); 97.7% (SEC-HPLC) - 98% (SDS-PAGE); 97.7% (SEC-HPLC)Forma y color:LiquidAfasevikumab
CAS:<p>Afasevikumab (RG 7624) is a fully humanised monoclonal antibody that targets and neutralises IL-17A and IL-17F,autoimmune diseases and inflammation.</p>Pureza:95%Forma y color:LiquidGevokizumab
CAS:<p>Gevokizumab (S-78989) is a humanised monoclonal antibody targeting IL-1β, allosteric regulation, diabetes, cancer, inflammation, and cardiovascular diseases.</p>Pureza:95%Forma y color:LiquidTirnovetmab
CAS:<p>Tirnovetmab (KIND-016) is a fully dog-derived monoclonal antibody targeting IL-31 with high affinity, suitable for investigating canine atopic dermatitis.</p>Pureza:95% - 95%Forma y color:LiquidLebrikizumab
CAS:<p>Lebrikizumab is a humanised monoclonal antibody that targets and inhibits interleukin 13 (IL-13), suppressing Th2 inflammation.asthma and atopic dermatitis.</p>Pureza:95%Forma y color:LiquidAnrukinzumab
CAS:<p>Anrukinzumab (IMA-638) is an anti-IL-13 mAb with anti-inflammatory effects, in development for ulcerative colitis and asthma.</p>Pureza:95%Forma y color:LiquidPicankibart
CAS:<p>Picankibart (IBI112) is a human recombinant monoclonal antibody targeting IL-23p19, indicated for psoriasis treatment.</p>Pureza:95% - 95%Forma y color:Liquid
