Receptor de IL
Los receptores de interleucina (receptores IL) son un grupo de receptores que se unen a las interleucinas, una familia de citocinas que desempeñan roles esenciales en la regulación del sistema inmunológico, la inflamación y la hematopoyesis. La desregulación de la señalización de interleucinas está asociada con diversas enfermedades inflamatorias y autoinmunes, lo que convierte a los receptores IL en objetivos críticos para la intervención terapéutica. Se están explorando los antagonistas de los receptores IL para el tratamiento de afecciones como la artritis reumatoide, la psoriasis y las enfermedades inflamatorias intestinales. En CymitQuimica, ofrecemos una gama de moduladores de receptores IL de alta calidad para apoyar su investigación en señalización de citocinas, inmunología y terapia de enfermedades inflamatorias.
Se han encontrado 112 productos de "Receptor de IL"
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Anakinra
CAS:<p>Anakinra (Raleukin) is an antagonist of recombinant, nonglycosylated human IL-1R. It is the first biological agent to block the pro-inflammatory effects.</p>Fórmula:C759H1186N208O232S10Pureza:95% - ≥95%Forma y color:SolidPeso molecular:17257.6IL-17A antagonist 1
CAS:<p>IL-17A antagonist 1 is an IL-17A antagonist for the study of interleukin-related inflammatory and immune diseases.</p>Fórmula:C33H41FN6O4Pureza:99.46%Forma y color:SolidPeso molecular:604.71Anti-Human IL-17A
CAS:<p>Anti-Human IL-17A (Secukinumab H chain) is a human monoclonal antibody targeting IL-17A, offering high affinity and low immunogenicity for psoriasis.</p>Pureza:98%Forma y color:LiquidPeso molecular:151 kDaAnti-Mouse IL-4 Antibody (11B11)
<p>Anti-Mouse IL-4 Antibody (11B11) is an inhibitory antibody targeting mouse IL-4, with the clone number 11B11.</p>Pureza:99%Forma y color:Odour LiquidOssirene
CAS:<p>Ossirene (AS101), a potent in vitro and in vivo immunomodulator, is a novel inhibitor of IL-1beta converting enzyme.</p>Fórmula:C2H4Cl3O2Te·H4NPureza:≥98%Forma y color:SolidPeso molecular:312.05Apilimod mesylate
CAS:<p>Apilimod mesylate (STA 5326 mesylate) is a potent IL-12/IL-23 inhibitor.</p>Fórmula:C25H34N6O8S2Pureza:99.51% - ≥95%Forma y color:SolidPeso molecular:610.7RO2959 Hydrochloride
CAS:<p>RO2959 Hydrochloride (RO2959 HCl) is a potent and selective inhibitor of CRAC channel(IC50: 402 nM). It is also a potent inhibitor of human IL-2.</p>Fórmula:C21H20ClF2N5OSPureza:99.24%Forma y color:SolidPeso molecular:463.93Dexamethasone Sodium Phosphate
CAS:<p>Dexamethasone Sodium Phosphate (Dexadreson) is a powerful anti-inflammatory and immunosuppressant synthetic glucocorticoid.</p>Fórmula:C22H30FO8P·2NaPureza:99.01% - 99.81%Forma y color:SolidPeso molecular:516.4IL-17A inhibitor 1
CAS:<p>IL-17A inhibitor 1 is a IL-17A inhibitor with IC50 of <9.45 nM in alphalisa assay. IL-17A inhibitor 1 inhibits HT-29 cells with IC50 of 9.3 nM.</p>Fórmula:C24H27F5N8O4Pureza:99.37% - 99.37%Forma y color:SolidPeso molecular:586.51Apilimod
CAS:<p>Apilimod (STA 5326) inhibits the production of IL-12 and IL-23 and reduces dendritic cell infiltration in psoriasis.</p>Fórmula:C23H26N6O2Pureza:99.38% - 99.89%Forma y color:SolidPeso molecular:418.49CP 424174
CAS:<p>CP 424174 blocks IL-1β processing (IC50: 210 nM), halts mature IL-1β formation, limits NLRP3, and is effective orally in vivo.</p>Fórmula:C22H29ClN2O4SPureza:>99.99%Forma y color:SolidPeso molecular:452.99Suplatast (Tosilate)
CAS:<p>Suplatast Tosilate (IPD 1151T) is a novel capsular anti-asthmatic drug. It ( IC50 above 100 μM) inhibits both IgE production, IL-4 and IL-5 synthesis.</p>Fórmula:C23H33NO7S2Pureza:99.34% - 99.65%Forma y color:White Or Off-White CrystalsPeso molecular:499.64Esonarimod
CAS:<p>Esonarimod (KE-298) is an antirheumatic drug.</p>Fórmula:C14H16O4SPureza:97.44%Forma y color:SolidPeso molecular:280.34GIBH-130
CAS:<p>GIBH-130 markedly inhibits the IL-1β secretion by activated microglia (IC50: 3.4 nM). GIBH-130 is an effective inhibitor of neuroinflammation.</p>Fórmula:C20H20N6OPureza:99.52%Forma y color:SolidPeso molecular:360.41GSK717
CAS:<p>GSK717: potent, selective NOD2 inhibitor; disrupts NOD2/TLR2 synergy; no effect on NOD1, TNFR1, TLR2.</p>Fórmula:C28H28N4O2Pureza:97.34% - 99.01%Forma y color:SolidPeso molecular:452.55VGX-1027
CAS:<p>VGX-1027 (GIT 27) is an isoxazole compound with various immunomodulatory properties.</p>Fórmula:C11H11NO3Pureza:99.54% - 99.86%Forma y color:SolidPeso molecular:205.21Secukinumab
CAS:<p>Secukinumab is a fully humanized monoclonal anti-IL-17A antibody and the first in its class to be approved by the US Food and Drug Administration for the</p>Pureza:97.4% (SDS-PAGE); 98.3% (SEC-HPLC) - 99.10%Forma y color:LiquidPeso molecular:147.93 kDaYM-90709
CAS:<p>YM-90709 is a new-type antagonist inhibiting the binding of interleukin-5 to the interleukin-5 receptor.</p>Fórmula:C22H21N3O2Pureza:>99.99%Forma y color:SolidPeso molecular:359.42AX-024 hydrochloride
CAS:<p>AX-024 hydrochloride (AX-024 HCl) is an cytokine release inhibitor which can strongly inhibit the production of IL-6, TNFα, IFN-γ, IL-10 and IL-17A.</p>Fórmula:C21H23ClFNO2Pureza:99.74%Forma y color:SolidPeso molecular:375.87Apilimod 2HCl
CAS:<p>Apilimod 2HCl (STA 5326 2HCl) is a PIKFYVE kinase inhibitor used in the study of amyotrophic lateral sclerosis.</p>Fórmula:C23H28Cl2N6O2Pureza:98.41%Forma y color:SolidPeso molecular:491.41Clodronate disodium tetrahydrate
CAS:<p>Clodronate disodium tetrahydrate (Clastoban) inhibits bone resorption and soft tissue calcification.</p>Fórmula:CH10Cl2Na2O10P2Pureza:98%Forma y color:SolidPeso molecular:360.92Satralizumab
CAS:<p>Satralizumab (SA-237) is a humanized antibody targeting interleukin-6 (IL-6), used in research on neuromyelitis optica spectrum disorder (NMOSD).</p>Pureza:95%Forma y color:LiquidSirukumab
CAS:<p>Sirukumab (CNTO-136) is a humanized monoclonal antibody binding to IL-6, inhibiting IL-6-mediated signaling and transcription activator activation.</p>Pureza:>95%Forma y color:LiquidPeso molecular:144.6 (kDa)Brazikumab
CAS:<p>Brazikumab (AMG 139) is a humanized antibody targeting IL-23 by binding to the P19 subunit, a selective IL-23p19 antagonist.</p>Pureza:98% (SDS-PAGE); 97.7% (SEC-HPLC) - 98% (SDS-PAGE); 97.7% (SEC-HPLC)Forma y color:LiquidAfasevikumab
CAS:<p>Afasevikumab (RG 7624) is a fully humanised monoclonal antibody that targets and neutralises IL-17A and IL-17F,autoimmune diseases and inflammation.</p>Pureza:95%Forma y color:LiquidGevokizumab
CAS:<p>Gevokizumab (S-78989) is a humanised monoclonal antibody targeting IL-1β, allosteric regulation, diabetes, cancer, inflammation, and cardiovascular diseases.</p>Pureza:95%Forma y color:LiquidTirnovetmab
CAS:<p>Tirnovetmab (KIND-016) is a fully dog-derived monoclonal antibody targeting IL-31 with high affinity, suitable for investigating canine atopic dermatitis.</p>Pureza:95% - 95%Forma y color:LiquidLebrikizumab
CAS:<p>Lebrikizumab is a humanised monoclonal antibody that targets and inhibits interleukin 13 (IL-13), suppressing Th2 inflammation.asthma and atopic dermatitis.</p>Pureza:95%Forma y color:LiquidAnrukinzumab
CAS:<p>Anrukinzumab (IMA-638) is an anti-IL-13 mAb with anti-inflammatory effects, in development for ulcerative colitis and asthma.</p>Pureza:95%Forma y color:LiquidPicankibart
CAS:<p>Picankibart (IBI112) is a human recombinant monoclonal antibody targeting IL-23p19, indicated for psoriasis treatment.</p>Pureza:95% - 95%Forma y color:LiquidCasdozokitug
CAS:<p>Casdozokitug is a human IgG1κ anti-IL-27 antibody that blocks immunosuppressive activity, relevant in tumor immunology and immune checkpoint therapy research.</p>Pureza:95% - 95%Forma y color:LiquidEbdarokimab
CAS:<p>Ebdarokimab (anti-IL-12/23 p40 mAb) inhibits the IL-12/IL-23 pathway and is under clinical investigation for SLE and plaque psoriasis.</p>Pureza:95%Forma y color:LiquidInolimomab
CAS:<p>Inolimomab is a monoclonal antibody targeting CD25 (IL-2R α chain) for studying acute graft-versus-host disease (aGVHD).</p>Pureza:95% - 95%Forma y color:LiquidBimekizumab
CAS:<p>Bimekizumab is a humanised monoclonal antibody targeting IL17A/IL17F, blocking inflammation-driven osteoblast differentiation.</p>Pureza:>99.99%Forma y color:LiquidAnti-Mouse IL-6R Antibody (15A7)
<p>Anti-Mouse IL-6R Antibody (15A7) is an antibody inhibitor targeting mouse IL-6R, derived from rats, widely used in research and experiments</p>Pureza:99% - 99%Forma y color:Odour LiquidZiralimumab
CAS:<p>Ziralimumab（ABX-RB2） is a monoclonal antibody that targets and inhibits IL-2 receptor, thereby modulating the immune response.</p>Pureza:95%Forma y color:LiquidRademikibart
CAS:<p>Rademikibart (CBP-201) is a human monoclonal antibody selective for IL-4Rα, exhibiting strong affinity with a KD of 20.7 pM for human IL-4Rα epitopes, without</p>Pureza:95%Forma y color:LiquidGumokimab
CAS:<p>Gumokimab (AK 111) is an anti-IL-17A mAb that blocks pro-inflammatory signaling, a candidate for psoriasis and ankylosing spondylitis.</p>Pureza:95%Forma y color:LiquidManfidokimab
CAS:<p>Manfidokimab is an anti-IL-4Rα mAb that blocks IL-4/IL-13 signaling, in trials for atopic dermatitis.</p>Pureza:95%Forma y color:LiquidBempikibart
CAS:<p>Bempikibart (ADX-914) is a fully humanised monoclonal antibody targeting IL-7Rα, inhibiting IL-17 and TSLP (Thymic stromal lymphopoietin), inflammation.</p>Pureza:95% - 95%Forma y color:LiquidLusvertikimab
CAS:<p>Lusvertikimab (OSE-127) is a humanized anti-IL7R antibody with anti-leukemic efficacy and can be used to study leukemia.</p>Pureza:95% - 98.4% (SDS-PAGE); 99% (SEC-HPLC)Forma y color:LiquidD228
CAS:<p>D228 is an oral anti-inflammatory,inhibi B and T lymphocytes, down-regulation of MyD88/TRAF6/p38 and up-regulation of IL-10,inflammatory bowel disease (IBD).</p>Fórmula:C22H28O12Pureza:99.91%Forma y color:SolidPeso molecular:484.45Etokimab
CAS:<p>Etokimab (ANB-020) is a humanised monoclonal antibody targeting IL-33, neutrophil migration, atopic dermatitis, asthma, and sinusitis.</p>Pureza:95%Forma y color:LiquidVopikitug
CAS:<p>Vopikitug is a humanized monoclonal antibody targeting IL-2RA with antitumor activity. It can be used to study cancer.</p>Pureza:99.1% (SDS-PAGE); 96.5% (SEC-HPLC) - 99.1% (SDS-PAGE); 96.5% (SEC-HPLC)Forma y color:LiquidA-802715
CAS:<p>A-802715 is a novel methylxanthine derivative that decreases the endogenous formation and blood levels of pro-inflammatory substances and increases the</p>Fórmula:C16H26N4O3Pureza:96.29%Forma y color:SolidPeso molecular:322.4BI605906
CAS:<p>BI605906 is an IKKβ inhibitor that can be used to study inflammatory skin diseases such as psoriasis.</p>Fórmula:C17H22F2N4O3S2Pureza:97.14%Forma y color:SolidPeso molecular:432.51IL-4-inhibitor-1
CAS:<p>IL-4 inhibitor: Binds IL-4 (Kd=1.8 μM), blocks activity (EC50=1.81 μM), selective vs. IL-13, stops IL-4-JAK1-STAT6 in THP-1 monocytes (EC50=3.1 μM).</p>Fórmula:C18H12FN3O2Pureza:98.78% - 99.53%Forma y color:SolidPeso molecular:321.31Resiniferatoxin
CAS:<p>Resiniferatoxin ((+)-Resiniferatoxin) is a highly potent synthetic TRPV1 agonist.Cost-effective and quality-assured.</p>Fórmula:C37H40O9Pureza:93.08% - 99.34%Forma y color:SolidPeso molecular:628.71IL-2-IN-1
CAS:<p>IL-2-IN-1 is a potent inhibitor of IL-2 (IC50: 1978 nM) and exhibits anti-proliferative effects.</p>Fórmula:C17H12F6N4O2Pureza:99.6%Forma y color:SolidPeso molecular:418.29Dersalazine
CAS:<p>Dersalazine, a PAF inhibitor, reduces IL-17 to treat colitis in rodents, potentially aiding ulcerative colitis patients.</p>Fórmula:C35H32N6O4Pureza:99.62%Forma y color:SolidPeso molecular:600.67
