Receptor de IL
Los receptores de interleucina (receptores IL) son un grupo de receptores que se unen a las interleucinas, una familia de citocinas que desempeñan roles esenciales en la regulación del sistema inmunológico, la inflamación y la hematopoyesis. La desregulación de la señalización de interleucinas está asociada con diversas enfermedades inflamatorias y autoinmunes, lo que convierte a los receptores IL en objetivos críticos para la intervención terapéutica. Se están explorando los antagonistas de los receptores IL para el tratamiento de afecciones como la artritis reumatoide, la psoriasis y las enfermedades inflamatorias intestinales. En CymitQuimica, ofrecemos una gama de moduladores de receptores IL de alta calidad para apoyar su investigación en señalización de citocinas, inmunología y terapia de enfermedades inflamatorias.
Se han encontrado 111 productos de "Receptor de IL"
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Anti-Mouse IL-4 Antibody (11B11)
Anti-Mouse IL-4 Antibody (11B11) is an inhibitory antibody targeting mouse IL-4, with the clone number 11B11.Pureza:99%Forma y color:Odour LiquidPeso molecular:150 kDaIL-17A antagonist 1
CAS:IL-17A antagonist 1 is an IL-17A antagonist for the study of interleukin-related inflammatory and immune diseases.Fórmula:C33H41FN6O4Pureza:99.46%Forma y color:SolidPeso molecular:604.71Anakinra
CAS:Anakinra (Raleukin) is an antagonist of recombinant, nonglycosylated human IL-1R. It is the first biological agent to block the pro-inflammatory effects.Fórmula:C759H1186N208O232S10Pureza:95% - ≥95%Forma y color:SolidPeso molecular:17257.6GIBH-130
CAS:GIBH-130 markedly inhibits the IL-1β secretion by activated microglia (IC50: 3.4 nM). GIBH-130 is an effective inhibitor of neuroinflammation.Fórmula:C20H20N6OPureza:99.52%Forma y color:SolidPeso molecular:360.41Clodronate disodium tetrahydrate
CAS:Clodronate disodium tetrahydrate (Clastoban) inhibits bone resorption and soft tissue calcification.Fórmula:CH10Cl2Na2O10P2Pureza:98%Forma y color:SolidPeso molecular:360.92Secukinumab
CAS:Secukinumab is a fully humanized monoclonal anti-IL-17A antibody and the first in its class to be approved by the US Food and Drug Administration for thePureza:97.4% (SDS-PAGE); 98.3% (SEC-HPLC) - 99.10%Forma y color:LiquidPeso molecular:147.93 kDaApilimod
CAS:Apilimod (STA 5326) inhibits the production of IL-12 and IL-23 and reduces dendritic cell infiltration in psoriasis.Fórmula:C23H26N6O2Pureza:99.38% - 99.89%Forma y color:SolidPeso molecular:418.49YM-90709
CAS:YM-90709 is a new-type antagonist inhibiting the binding of interleukin-5 to the interleukin-5 receptor.Fórmula:C22H21N3O2Pureza:>99.99%Forma y color:SolidPeso molecular:359.42Apilimod mesylate
CAS:Apilimod mesylate (STA 5326 mesylate) is a potent IL-12/IL-23 inhibitor.Fórmula:C25H34N6O8S2Pureza:99.51% - ≥95%Forma y color:SolidPeso molecular:610.7VGX-1027
CAS:VGX-1027 (GIT 27) is an isoxazole compound with various immunomodulatory properties.Fórmula:C11H11NO3Pureza:99.54% - 99.86%Forma y color:SolidPeso molecular:205.21Apilimod 2HCl
CAS:Apilimod 2HCl (STA 5326 2HCl) is a PIKFYVE kinase inhibitor used in the study of amyotrophic lateral sclerosis.Fórmula:C23H28Cl2N6O2Pureza:98.41%Forma y color:SolidPeso molecular:491.41AF 12198 Acetate
AF 12198 Acetate is a novel low molecular weight antagonist of IL-1Fórmula:C98H127N19O24Pureza:95.27%Forma y color:SolidPeso molecular:1955.17Lyn peptide inhibitor acetate
Potent, cell-permeable Lyn inhibitor; hinders IL-5 receptor signaling, vital for asthma/allergy research.Fórmula:C117H188N30O26Pureza:98%Forma y color:SolidPeso molecular:2430.98Esonarimod
CAS:Esonarimod (KE-298) is an antirheumatic drug.Fórmula:C14H16O4SPureza:97.44%Forma y color:SolidPeso molecular:280.34Suplatast (Tosilate)
CAS:Suplatast Tosilate (IPD 1151T) is a novel capsular anti-asthmatic drug. It ( IC50 above 100 μM) inhibits both IgE production, IL-4 and IL-5 synthesis.Fórmula:C23H33NO7S2Pureza:99.34% - 99.65%Forma y color:White Or Off-White CrystalsPeso molecular:499.64IL-17A inhibitor 1
CAS:IL-17A inhibitor 1 is a IL-17A inhibitor with IC50 of <9.45 nM in alphalisa assay. IL-17A inhibitor 1 inhibits HT-29 cells with IC50 of 9.3 nM.
Fórmula:C24H27F5N8O4Pureza:99.37% - 99.37%Forma y color:SolidPeso molecular:586.51CP 424174
CAS:CP 424174 blocks IL-1β processing (IC50: 210 nM), halts mature IL-1β formation, limits NLRP3, and is effective orally in vivo.Fórmula:C22H29ClN2O4SPureza:>99.99%Forma y color:SolidPeso molecular:452.99GSK717
CAS:GSK717: potent, selective NOD2 inhibitor; disrupts NOD2/TLR2 synergy; no effect on NOD1, TNFR1, TLR2.
Fórmula:C28H28N4O2Pureza:97.34% - 99.01%Forma y color:SolidPeso molecular:452.55Sirukumab
CAS:Sirukumab (CNTO-136) is a humanized monoclonal antibody binding to IL-6, inhibiting IL-6-mediated signaling and transcription activator activation.Pureza:>95%Forma y color:LiquidPeso molecular:144.58 kDaBrazikumab
CAS:Brazikumab (AMG 139) is a humanized antibody targeting IL-23 by binding to the P19 subunit, a selective IL-23p19 antagonist.Pureza:98% (SDS-PAGE); 97.7% (SEC-HPLC) - 98% (SDS-PAGE); 97.7% (SEC-HPLC)Forma y color:LiquidPeso molecular:145.78 kDaSatralizumab
CAS:Satralizumab (SA-237) is a humanized antibody targeting interleukin-6 (IL-6), used in research on neuromyelitis optica spectrum disorder (NMOSD).Pureza:95%Forma y color:LiquidPeso molecular:143.42 kDaInolimomab
CAS:Inolimomab is a monoclonal antibody targeting CD25 (IL-2R α chain) for studying acute graft-versus-host disease (aGVHD).Pureza:95% - >95.0% (SDS-PAGE); 99.49% (SEC-HPLC)Forma y color:LiquidPeso molecular:145.34 kDaPicankibart
CAS:Picankibart (IBI112) is a human recombinant monoclonal antibody targeting IL-23p19, indicated for psoriasis treatment.Pureza:95% - 97.0% (SDS-PAGE); 99.4% (SEC-HPLC)Forma y color:LiquidPeso molecular:144.75 kDaManfidokimab
CAS:Manfidokimab is an anti-IL-4Rα mAb that blocks IL-4/IL-13 signaling, in trials for atopic dermatitis.Pureza:95%Forma y color:LiquidPeso molecular:~150 kDaBimekizumab
CAS:Bimekizumab is a humanised monoclonal antibody targeting IL17A/IL17F, blocking inflammation-driven osteoblast differentiation.Pureza:>99.99%Forma y color:LiquidPeso molecular:147.24 kDaEbdarokimab
CAS:Ebdarokimab (anti-IL-12/23 p40 mAb) inhibits the IL-12/IL-23 pathway and is under clinical investigation for SLE and plaque psoriasis.Pureza:95%Forma y color:LiquidPeso molecular:145.66 kDaAnrukinzumab
CAS:Anrukinzumab (IMA-638) is an anti-IL-13 mAb with anti-inflammatory effects, in development for ulcerative colitis and asthma.Pureza:95%Forma y color:LiquidPeso molecular:145.38 kDaZiralimumab
CAS:Ziralimumab（ABX-RB2） is a monoclonal antibody that targets and inhibits IL-2 receptor, thereby modulating the immune response.Pureza:95%Forma y color:LiquidAnti-Mouse IL-1a Antibody (ALF-161)
Anti-Mouse IL-1a Antibody (ALF-161) is a monoclonal antibody inhibitor targeting mouse IL-1α. inhibit CD8+ T cell responses and reverse myeloid cell expansion.Pureza:95%Forma y color:Odour LiquidCasdozokitug
CAS:Casdozokitug is a human IgG1κ anti-IL-27 antibody that blocks immunosuppressive activity, relevant in tumor immunology and immune checkpoint therapy research.Pureza:95% - 95.1% (SDS-PAGE); 97.2% (SEC-HPLC)Forma y color:LiquidPeso molecular:147.35 kDaGumokimab
CAS:Gumokimab (AK 111) is an anti-IL-17A mAb that blocks pro-inflammatory signaling, a candidate for psoriasis and ankylosing spondylitis.Pureza:95%Forma y color:LiquidPeso molecular:146.50 kDaBempikibart
CAS:Bempikibart (ADX-914) is a fully humanised monoclonal antibody targeting IL-7Rα, inhibiting IL-17 and TSLP (Thymic stromal lymphopoietin), inflammation.Pureza:95% - 98.9% (SDS-PAGE); 97.4% (SEC-HPLC)Forma y color:LiquidPeso molecular:145.75 kDaAnti-Mouse IL-6R Antibody (15A7)
Anti-Mouse IL-6R Antibody (15A7) is an antibody inhibitor targeting mouse IL-6R, derived from rats, widely used in research and experimentsPureza:99% - 99%Forma y color:Odour LiquidLebrikizumab
CAS:Lebrikizumab is a humanised monoclonal antibody that targets and inhibits interleukin 13 (IL-13), suppressing Th2 inflammation.asthma and atopic dermatitis.Pureza:95%Forma y color:LiquidPeso molecular:145.27 kDaTirnovetmab
CAS:Tirnovetmab (KIND-016) is a fully dog-derived monoclonal antibody targeting IL-31 with high affinity, suitable for investigating canine atopic dermatitis.Pureza:95% - 96.6% (SDS-PAGE); 99.4% (SEC-HPLC)Forma y color:LiquidPeso molecular:148.83 kDaGevokizumab
CAS:Gevokizumab (S-78989) is a humanised monoclonal antibody targeting IL-1β, allosteric regulation, diabetes, cancer, inflammation, and cardiovascular diseases.Pureza:95%Forma y color:LiquidPeso molecular:144.93 kDaAfasevikumab
CAS:Afasevikumab (RG 7624) is a fully humanised monoclonal antibody that targets and neutralises IL-17A and IL-17F,autoimmune diseases and inflammation.Pureza:95%Forma y color:LiquidPeso molecular:146.07 kDaSapelizumab
Sapelizumab is a humanised antibody targeting IL-6Ra/CD126, huIgG2-type heavy chains and huκ-type light chains, IL-6 antagonist NMOSD.Peso molecular:~150 kDaLusvertikimab
CAS:Lusvertikimab (OSE-127) is a humanized anti-IL7R antibody with anti-leukemic efficacy and can be used to study leukemia.Pureza:95% - 98.4% (SDS-PAGE); 99% (SEC-HPLC)Forma y color:LiquidPeso molecular:145.63 kDaD228
CAS:D228 is an oral anti-inflammatory,inhibi B and T lymphocytes, down-regulation of MyD88/TRAF6/p38 and up-regulation of IL-10,inflammatory bowel disease (IBD).Fórmula:C22H28O12Pureza:99.91%Forma y color:SolidPeso molecular:484.45Etokimab
CAS:Etokimab (ANB-020) is a humanised monoclonal antibody targeting IL-33, neutrophil migration, atopic dermatitis, asthma, and sinusitis.Pureza:95%Forma y color:LiquidPeso molecular:146.54 kDaVopikitug
CAS:Vopikitug is a humanized monoclonal antibody targeting IL-2RA with antitumor activity. It can be used to study cancer.Pureza:99.1% (SDS-PAGE); 96.5% (SEC-HPLC) - 99.1% (SDS-PAGE); 96.5% (SEC-HPLC)Forma y color:LiquidPeso molecular:144.53 kDaBI605906
CAS:BI605906 is an IKKβ inhibitor that can be used to study inflammatory skin diseases such as psoriasis.
Fórmula:C17H22F2N4O3S2Pureza:97.14%Forma y color:SolidPeso molecular:432.51A-802715
CAS:A-802715 is a novel methylxanthine derivative that decreases the endogenous formation and blood levels of pro-inflammatory substances and increases theFórmula:C16H26N4O3Pureza:96.29%Forma y color:SolidPeso molecular:322.4LMT-28
CAS:LMT-28 is an inhibitor of IL-6 and selectively inhibits IL-6-induced phosphorylation of gp130, STAT3, and JAK2.Fórmula:C17H29NO4Pureza:97.55%Forma y color:SolidPeso molecular:311.42Dersalazine
CAS:Dersalazine, a PAF inhibitor, reduces IL-17 to treat colitis in rodents, potentially aiding ulcerative colitis patients.
Fórmula:C35H32N6O4Pureza:99.62%Forma y color:SolidPeso molecular:600.67NFAT Transcription Factor Regulator-1
CAS:NFAT Transcription Factor Regulator-1 is an synthesis inhibitor of IL-2 (IC50 of 182 nM).Fórmula:C17H10F6N4O2Pureza:99.90%Forma y color:SolidPeso molecular:416.28Ref: TM-T12218
1mg44,00€1mL*10mM (DMSO)87,00€5mg88,00€10mg135,00€25mg243,00€50mg358,00€100mg512,00€500mg1.018,00€IL-4-inhibitor-1
CAS:IL-4 inhibitor: Binds IL-4 (Kd=1.8 μM), blocks activity (EC50=1.81 μM), selective vs. IL-13, stops IL-4-JAK1-STAT6 in THP-1 monocytes (EC50=3.1 μM).Fórmula:C18H12FN3O2Pureza:99.53% - 99.89%Forma y color:SolidPeso molecular:321.31Ref: TM-T36527
1mg44,00€1mL*10mM (DMSO)130,00€5mg172,00€10mg313,00€25mg530,00€50mg757,00€100mg1.044,00€Resiniferatoxin
CAS:Resiniferatoxin ((+)-Resiniferatoxin) is a highly potent synthetic TRPV1 agonist.Cost-effective and quality-assured.Fórmula:C37H40O9Pureza:93.08% - 99.34%Forma y color:SolidPeso molecular:628.71BIRT-377
CAS:BIRT-377: orally active, hinders ICAM-1/LFA-1, blocks IL-2, useful for immune research. (Ki=25.8 nM).Fórmula:C18H15BrCl2N2O2Pureza:99.93%Forma y color:SolidPeso molecular:442.13
