Receptor de IL
Los receptores de interleucina (receptores IL) son un grupo de receptores que se unen a las interleucinas, una familia de citocinas que desempeñan roles esenciales en la regulación del sistema inmunológico, la inflamación y la hematopoyesis. La desregulación de la señalización de interleucinas está asociada con diversas enfermedades inflamatorias y autoinmunes, lo que convierte a los receptores IL en objetivos críticos para la intervención terapéutica. Se están explorando los antagonistas de los receptores IL para el tratamiento de afecciones como la artritis reumatoide, la psoriasis y las enfermedades inflamatorias intestinales. En CymitQuimica, ofrecemos una gama de moduladores de receptores IL de alta calidad para apoyar su investigación en señalización de citocinas, inmunología y terapia de enfermedades inflamatorias.
Se han encontrado 110 productos de "Receptor de IL"
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VGX-1027
CAS:VGX-1027 (GIT 27) is an isoxazole compound with various immunomodulatory properties.Fórmula:C11H11NO3Pureza:99.54% - 99.86%Forma y color:SolidPeso molecular:205.21Apilimod
CAS:Apilimod (STA 5326) inhibits the production of IL-12 and IL-23 and reduces dendritic cell infiltration in psoriasis.Fórmula:C23H26N6O2Pureza:99.38% - 99.89%Forma y color:SolidPeso molecular:418.49IL-17A inhibitor 1
CAS:IL-17A inhibitor 1 is a IL-17A inhibitor with IC50 of <9.45 nM in alphalisa assay. IL-17A inhibitor 1 inhibits HT-29 cells with IC50 of 9.3 nM.
Fórmula:C24H27F5N8O4Pureza:99.37% - 99.37%Forma y color:SolidPeso molecular:586.51Secukinumab
CAS:Secukinumab is a fully humanized monoclonal anti-IL-17A antibody and the first in its class to be approved by the US Food and Drug Administration for thePureza:97.4% (SDS-PAGE); 98.3% (SEC-HPLC) - 99.10%Forma y color:LiquidPeso molecular:147.93 kDaApilimod mesylate
CAS:Apilimod mesylate (STA 5326 mesylate) is a potent IL-12/IL-23 inhibitor.Fórmula:C25H34N6O8S2Pureza:99.51% - ≥95%Forma y color:SolidPeso molecular:610.7Lyn peptide inhibitor acetate
Potent, cell-permeable Lyn inhibitor; hinders IL-5 receptor signaling, vital for asthma/allergy research.Fórmula:C117H188N30O26Pureza:98%Forma y color:SolidPeso molecular:2430.98YM-90709
CAS:YM-90709 is a new-type antagonist inhibiting the binding of interleukin-5 to the interleukin-5 receptor.Fórmula:C22H21N3O2Pureza:>99.99%Forma y color:SolidPeso molecular:359.42RO2959 Hydrochloride
CAS:RO2959 Hydrochloride (RO2959 HCl) is a potent and selective inhibitor of CRAC channel(IC50: 402 nM). It is also a potent inhibitor of human IL-2.Fórmula:C21H20ClF2N5OSPureza:99.24%Forma y color:SolidPeso molecular:463.93Brazikumab
CAS:Brazikumab (AMG 139) is a humanized antibody targeting IL-23 by binding to the P19 subunit, a selective IL-23p19 antagonist.Pureza:98% (SDS-PAGE); 97.7% (SEC-HPLC) - 98% (SDS-PAGE); 97.7% (SEC-HPLC)Forma y color:LiquidSatralizumab
CAS:Satralizumab (SA-237) is a humanized antibody targeting interleukin-6 (IL-6), used in research on neuromyelitis optica spectrum disorder (NMOSD).Pureza:95%Forma y color:LiquidPeso molecular:143.42 kDaSirukumab
CAS:Sirukumab (CNTO-136) is a humanized monoclonal antibody binding to IL-6, inhibiting IL-6-mediated signaling and transcription activator activation.Pureza:>95%Forma y color:LiquidPeso molecular:144.6 (kDa)Tirnovetmab
CAS:Tirnovetmab (KIND-016) is a fully dog-derived monoclonal antibody targeting IL-31 with high affinity, suitable for investigating canine atopic dermatitis.Pureza:95% - 96.6% (SDS-PAGE); 99.4% (SEC-HPLC)Forma y color:LiquidPeso molecular:148.83 kDaBimekizumab
CAS:Bimekizumab is a humanised monoclonal antibody targeting IL17A/IL17F, blocking inflammation-driven osteoblast differentiation.Pureza:>99.99%Forma y color:LiquidInolimomab
CAS:Inolimomab is a monoclonal antibody targeting CD25 (IL-2R α chain) for studying acute graft-versus-host disease (aGVHD).Pureza:95% - >95.0% (SDS-PAGE); 99.49% (SEC-HPLC)Forma y color:LiquidCasdozokitug
CAS:Casdozokitug is a human IgG1κ anti-IL-27 antibody that blocks immunosuppressive activity, relevant in tumor immunology and immune checkpoint therapy research.Pureza:95% - 95.1% (SDS-PAGE); 97.2% (SEC-HPLC)Forma y color:LiquidPeso molecular:147.35 kDaPicankibart
CAS:Picankibart (IBI112) is a human recombinant monoclonal antibody targeting IL-23p19, indicated for psoriasis treatment.Pureza:95% - 97.0% (SDS-PAGE); 99.4% (SEC-HPLC)Forma y color:LiquidPeso molecular:144.75 kDaBempikibart
CAS:Bempikibart (ADX-914) is a fully humanised monoclonal antibody targeting IL-7Rα, inhibiting IL-17 and TSLP (Thymic stromal lymphopoietin), inflammation.Pureza:95% - 98.9% (SDS-PAGE); 97.4% (SEC-HPLC)Forma y color:LiquidSapelizumab
Sapelizumab is a humanised antibody targeting IL-6Ra/CD126, huIgG2-type heavy chains and huκ-type light chains, IL-6 antagonist NMOSD.Peso molecular:~150 kDaLebrikizumab
CAS:Lebrikizumab is a humanised monoclonal antibody that targets and inhibits interleukin 13 (IL-13), suppressing Th2 inflammation.asthma and atopic dermatitis.Pureza:95%Forma y color:LiquidPeso molecular:145.27 kDaAfasevikumab
CAS:Afasevikumab (RG 7624) is a fully humanised monoclonal antibody that targets and neutralises IL-17A and IL-17F,autoimmune diseases and inflammation.Pureza:95%Forma y color:LiquidPeso molecular:146.07 kDa
