JNK
Las JNK (c-Jun N-terminal kinases) son un subgrupo de la familia MAPK que responden a estímulos de estrés, como citoquinas, radiación ultravioleta y choque térmico, y están involucradas en el control de la apoptosis, la inflamación y las respuestas inmunitarias. La señalización de JNK es crucial para la regulación de las respuestas celulares al estrés y se ha implicado en diversas enfermedades, incluidas las neurodegenerativas, el cáncer y las afecciones inflamatorias. En CymitQuimica, ofrecemos una gama de moduladores de la vía JNK para apoyar su investigación en señalización de estrés, apoptosis y patología de enfermedades.
Se han encontrado 97 productos de "JNK"
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IQ-1S free acid
CAS:<p>IQ-1S free acid (IQ-1S) is an effective and specific c-Jun N-Terminal Kinase Inhibitor. IQ-1S inhibits murine delayed-type hypersensitivity.</p>Fórmula:C15H9N3OPureza:97.92% - 99.05%Forma y color:SolidPeso molecular:247.25Taurochenodeoxycholic acid sodium
CAS:<p>Sodium taurochenodeoxycholate: induces apoptosis, anti-inflammatory, boosts insulin, stimulates α2-cells, increases [Ca(2+)](c).</p>Fórmula:C26H44NNaO6SPureza:98.23% - 99.45%Forma y color:White To Off-White PowderPeso molecular:521.68Fasudil hydrochloride
CAS:<p>Fasudil hydrochloride (HA-1077) is a potent inhibitor of ROCK1, PKA, PKC, and MLCK with Ki of 0.33 μM, 1.0 μM, 9.3 μM and 55 μM, respectively.</p>Fórmula:C14H18ClN3O2SPureza:99.54% - ≥95%Forma y color:White SolidPeso molecular:327.83CC-90001
CAS:<p>CC-90001 is an orally administered c-Jun N-terminal kinase (JNK) inhibitor with bias for JNK1 over JNK2.</p>Fórmula:C16H27N5O2Pureza:99.96%Forma y color:SolidPeso molecular:321.42Esculentoside H
CAS:<p>Phytolaccaceae has anti-tumor activity, the mechanism may be related to the capacity of Esculentoside H for TNF release.</p>Fórmula:C48H76O21Pureza:98.04% - 99.3%Forma y color:SolidPeso molecular:989.1TCS JNK 5a
CAS:<p>TCS JNK 5a (SC202671) is an effective, specific inhibitor of JNK3(pIC50= 6.7), JNK2(pIC50=6.5).</p>Fórmula:C20H16N2OSPureza:99.22% - 99.51%Forma y color:SolidPeso molecular:332.42Ginsenoside Re
CAS:<p>Ginsenoside Re (Ginsenoside B2) may have properties that inhibit or prevent the growth of tumors.</p>Fórmula:C48H82O18Pureza:99.12% - >99.99%Forma y color:White PowderPeso molecular:947.15Juglanin
CAS:<p>Juglanin is a JNK activator. Juglanin with inflammation and anti-tumor activities. It can induce apoptosis and autophagy on human breast cancer cells.</p>Fórmula:C20H18O10Pureza:98.8% - 99.33%Forma y color:SolidPeso molecular:418.35Tomatidine
CAS:<p>Tomatidine serves as an anti-inflammatory agent by inhibiting NF-κB and JNK signaling pathways.</p>Fórmula:C27H45NO2Pureza:99.94% - 99.98%Forma y color:SolidPeso molecular:415.65Sesamolin
CAS:<p>Sesamolin and sesamin guard nerves, reduce microglia damage by blocking p38 MAPK and caspase-3, and curb nitric oxide in stimulated cells.</p>Fórmula:C20H18O7Pureza:98.77% - 99.04%Forma y color:SolidPeso molecular:370.35Pamapimod
CAS:<p>Pamapimod (R1503) (R-1503, Ro4402257) is a novel, selective inhibitor of p38 mitogen-activated protein kinase.</p>Fórmula:C19H20F2N4O4Pureza:99.52% - 99.99%Forma y color:SolidPeso molecular:406.38GSK649A
CAS:<p>GSK649A is a novel activator of Satellite Cell Proliferation, it could enhance repair of Damaged Muscle.</p>Fórmula:C15H12ClFN6OSPureza:98%Forma y color:SolidPeso molecular:378.81SX 011
CAS:<p>SX 011 is a p38α inhibitor.</p>Fórmula:C26H27ClFN3O3Pureza:98%Forma y color:SolidPeso molecular:483.96JNK-1-IN-1
CAS:<p>JNK-1-IN-1 is an inhibitor specifically targeting JNK-1, also exhibiting inhibition of MKK7 with an IC50 value of 7.8μM.</p>Fórmula:C24H22N6SForma y color:SolidPeso molecular:426.54SR 3576
CAS:<p>JNK3 inhibitor, potent and selective</p>Fórmula:C27H27N5O5Pureza:98%Forma y color:SolidPeso molecular:501.53TOPK-p38/JNK-IN-1
CAS:<p>TOPK-p38/JNK-IN-1 (Compound B12) is an orally active inhibitor of the TOPK-p38/JNK signaling pathway, with an IC50 value of 2.14 μM for the inhibition of NO</p>Fórmula:C17H15F3N2O4Forma y color:SolidPeso molecular:368.31SR-3306
CAS:<p>SR-3306 is a brain-penetrant and selective pan-JNK (JNK1/2/3) inhibitor with IC50 values of 67 nM, 283 nM, 159 nM.Cost-effective and quality-assured.</p>Fórmula:C28H26N8OPureza:99.38% - 99.71%Forma y color:SolidPeso molecular:490.56BSJ-04-122
CAS:<p>BSJ-04-122: MKK4/7 inhibitor with IC50s of 4 nM & 181 nM, used in cancer research.</p>Fórmula:C15H12ClN5OPureza:97.61%Forma y color:SolidPeso molecular:313.74SR-3737
CAS:<p>SR-3737 is potent both JNK3 and p38 inhibitor.</p>Fórmula:C29H25FN4O4Pureza:98%Forma y color:SolidPeso molecular:512.53J30-8
CAS:<p>J30-8 is a JNK3 inhibitor (IC50: 40 nM) with neuroprotective activity and can be used to study neurodegenerative diseases such as Alzheimer's disease.</p>Fórmula:C17H9ClFN3O2SPureza:99.90%Forma y color:SolidPeso molecular:373.79
