MAPK
Las MAPK son una familia de quinasas de proteínas involucradas en una variedad de procesos celulares, incluyendo crecimiento, proliferación, diferenciación y respuestas al estrés. La vía de señalización MAPK consta de varios niveles, incluidos ERK, JNK y p38 MAPK, cada uno con roles distintos en la función celular. La desregulación de la señalización MAPK está vinculada al cáncer, las enfermedades inflamatorias y los trastornos metabólicos. En CymitQuimica, ofrecemos una amplia gama de inhibidores y activadores de MAPK para apoyar su investigación en biología celular, transducción de señales y mecanismos de enfermedades.
Se han encontrado 885 productos de "MAPK"
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KRAS G12D inhibitor 6
CAS:<p>KRAS G12D inhibitor 6 is an efficacious compound that effectively inhibits KRAS G12D.</p>Fórmula:C32H37ClN8O2Forma y color:SolidPeso molecular:601.15Vacquinol-1
CAS:<p>Vacquinol-1 is an MKK4 activator, which rapidly and selectively induces glioma cell death.</p>Fórmula:C21H21ClN2OPureza:98.67%Forma y color:SolidPeso molecular:352.86Peraquinsin
CAS:<p>Peraquinsin is a MK2 activator that can be utilized in the research of vascular or endothelial barrier disorders and functions as an antihypertensive agent [1].</p>Fórmula:C23H28N4O4Forma y color:SolidPeso molecular:424.49G12Si-5
CAS:<p>G12Si-5: covalent K-RasG12S inhibitor, Ki 26 μM, targets S-IIP domain, hinders oncogenic signaling, lowers ERK phosphorylation in mutant cells.</p>Fórmula:C31H29ClFN5O3Forma y color:SolidPeso molecular:574.05Cobimetinib (R-enantiomer)
CAS:<p>Cobimetinib R-enantiomer is the less active R-enantiomer of Cobimetinib which is a selective MEK inhibitor.</p>Fórmula:C21H21F3IN3O2Pureza:98%Forma y color:SolidPeso molecular:531.318PROTAC SOS1 degrader-4
<p>PROTAC SOS1 Degrader-4 (compound 10) is a potent degrader of SOS1 and exhibits antiproliferative activity [1].</p>Fórmula:C53H65ClN8O7SPureza:98%Forma y color:SolidPeso molecular:993.65XY-02-082
CAS:<p>XY-02-082 is a covalent guanosine-mimetic inhibitor targeting G12C KRAS.</p>Fórmula:C15H21ClF2N6O11P2Forma y color:SolidPeso molecular:596.76TAT-DEF-Elk-1
CAS:<p>TAT-DEF-Elk-1 is a cell-penetrating peptide Elk-1 inhibitor.</p>Fórmula:C155H259N57O40Pureza:98%Forma y color:SolidPeso molecular:3561.136Enniatin B1
CAS:<p>Enniatin B1, a Fusarium mycotoxin, crosses the blood-brain barrier and modulates ERK, NF-κB, and ACAT with an IC50 of 73 μM.</p>Fórmula:C34H59N3O9Pureza:98%Forma y color:SolidPeso molecular:653.858JH295
CAS:<p>JH295: potent, selective Nek2 inhibitor (IC50 = 770 nM), irreversibly targets Cys22, no effect on Cdk1, Aurora B, Plk1, or spindle mechanisms.</p>Fórmula:C18H16N4O2Forma y color:SolidPeso molecular:320.352LC-2
CAS:LC-2 (PROTAC KRASG12C Degrader-LC-2) is a novel von Hippel-Lindau-based PROTAC degrader of endogenous KRAS G12C with a DC50 between 0.25 and 0.76 μM.LC-2 is aFórmula:C59H71ClFN11O7SPureza:98%Forma y color:SolidPeso molecular:1132.78Tunlametinib
CAS:<p>Tunlametinib is a MEK1/2 inhibitor (IC50=1.9 nM) for treating RAS/RAF-driven cancers.</p>Fórmula:C16H12F2IN3O3SPureza:98.72%Forma y color:SolidPeso molecular:491.25Anti-ERK2 Antibody (5V598)
<p>Anti-ERK2 Antibody (5V598) is a Rabbit antibody targeting ERK2. Anti-ERK2 Antibody (5V598) can be used in ELISA.</p>Forma y color:Odour LiquidAnti-ERK2 Antibody (4F551)
<p>Anti-ERK2 Antibody (4F551) is a Rabbit antibody targeting ERK2. Anti-ERK2 Antibody (4F551) can be used in ELISA,FCM.</p>Forma y color:Odour LiquidAnti-ERK2 Antibody (9C922)
<p>Anti-ERK2 Antibody (9C922) is a Mouse antibody targeting ERK2. Anti-ERK2 Antibody (9C922) can be used in WB,ELISA.</p>Forma y color:Odour LiquidTAK1-IN-3
CAS:<p>TAK1-IN-3 is a novel ATP-competitive TAK1 inhibitor for the study of cancer.</p>Fórmula:C16H19N3O2SPureza:98.88%Forma y color:SolidPeso molecular:317.41Enniatin B
CAS:<p>Enniatins B decreases the activation of ERK (p44/p42).</p>Fórmula:C33H57N3O9Pureza:98%Forma y color:SolidPeso molecular:639.831TRPM4 inhibitor 8
CAS:<p>TRPM4 inhibitor 8 is an inhibitor of Transient receptor potential melastatin 4(TRPM4) which contributes to viability, migration, cell cycle shift, and adhesion.</p>Fórmula:C11H17BrN2Pureza:97%Forma y color:SolidPeso molecular:257.17S6K1-IN-DG2
CAS:<p>S6K1-IN-DG2(S6K1InhibitorDG2) is a potent p70S6K inhibitor with an IC50 value of less than 100 nM.</p>Fórmula:C16H17BrN6OPureza:99.25%Forma y color:SolidPeso molecular:389.25RAS GTPase inhibitor 1
CAS:RAS GTPase inhibitor 1 is a RAS GTPase inhibitor with potential antitumor activity.Fórmula:C27H28ClF4N5O2Pureza:98.43%Forma y color:SolidPeso molecular:565.99
