
MAPK
Las MAPK son una familia de quinasas de proteínas involucradas en una variedad de procesos celulares, incluyendo crecimiento, proliferación, diferenciación y respuestas al estrés. La vía de señalización MAPK consta de varios niveles, incluidos ERK, JNK y p38 MAPK, cada uno con roles distintos en la función celular. La desregulación de la señalización MAPK está vinculada al cáncer, las enfermedades inflamatorias y los trastornos metabólicos. En CymitQuimica, ofrecemos una amplia gama de inhibidores y activadores de MAPK para apoyar su investigación en biología celular, transducción de señales y mecanismos de enfermedades.
Se han encontrado 892 productos de "MAPK"
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B-Raf IN 13
CAS:<p>B-Raf IN 13 is a potent B-Raf inhibitor with anticancer activity.B-Raf IN 13 has an IC50 of 3.55 nM in the BRAF V600E enzyme assay.</p>Fórmula:C19H19ClFN3O4SPureza:99.41% - >99.99%Forma y color:SoildPeso molecular:439.89SMAP-2
CAS:SMAP-2: oral PP2A activator, targets Aα subunit, halts KRAS-mutant lung cancer growth.Fórmula:C27H27F3N2O4SPureza:98%Forma y color:SolidPeso molecular:532.57GGTI-286 hydrochloride
CAS:GGTI-286 HCl strongly inhibits GGTase I (IC50: 2 μM) and K-Ras4B farnesylation (IC50: 1 μM).Fórmula:C23H32ClN3O3SForma y color:SolidPeso molecular:466.04D-87503
CAS:D-87503 is a dual extracellular signaling-related kinase (ERK)/PI3K inhibitor.Fórmula:C17H15N5OSForma y color:SolidPeso molecular:337.4Avutometinib potassium
CAS:Avutometinib potassium, a MEKi, blocks Delta and Omicron infection in airway cells, potentially lessening disease severity.Fórmula:C21H17FKN5O5SForma y color:SolidPeso molecular:509.55KRAS G12C inhibitor 43
CAS:<p>KRAS G12C inhibitor 43 strongly blocks KRAS G12C, H358 cell growth (IC50: 0.001-1μM), less effective on A549, HCC cells (IC50>1μM).</p>Fórmula:C33H35N7O3Forma y color:SolidPeso molecular:577.68KRAS inhibitor-10
CAS:KRAS inhibitor-10: potent, selective KRAS protein blocker; effective in various cancers; oral; tetrahydroisoquinoline class.Fórmula:C30H37N3O5Forma y color:SolidPeso molecular:519.63KRAS G12D inhibitor 13
CAS:KRAS G12D inhibitor 13 targets KRAS G12D-mediated cancers with potency (WO2021108683A1, cmpd 142).Fórmula:C31H33F2N7O3Forma y color:SolidPeso molecular:589.64PB1
CAS:PB1, a stable borane-protected TCEP analogue, effectively reduces disulfides intracellularly and aids retinal cell survival post-axotomy.Fórmula:C14H22BO4PForma y color:SolidPeso molecular:296.11CP-944629
CAS:CP-944629 is a novel, potent, and selective inhibitor of p38alpha.Fórmula:C19H15F3N4OPureza:98%Forma y color:SolidPeso molecular:372.34BNC-1
CAS:BNC-1 reduces amyloid in mice, enhances synapses by activating Elk-1.Fórmula:C16H14N2O3Pureza:98%Forma y color:SolidPeso molecular:282.29KRAS G12D inhibitor 10
CAS:KRAS G12D inhibitor 10 targets KRAS G12D in cancer research (WO2021108683A1, compound 34).Fórmula:C33H41ClN8O2Forma y color:SolidPeso molecular:617.18LY-2584702 hydrochloride
CAS:<p>Ly-2584702 hydrochloride is a p70S6K selective ATP competitive inhibitor with IC50 of 4 nM.In the S6K1 enzyme assay, the IC50 of LY-2584702 was 2 nM.</p>Fórmula:C21H20ClF4N7Pureza:98%Forma y color:SolidPeso molecular:481.88Migoprotafib
CAS:Migoprotafib (GDC-1971) is a potent and highly selective SHP2 (Src Homology-2 Domain-Containing Phosphatase 2) inhibitor for advanced solid tumours.Fórmula:C25H26N8OPureza:98.31%Forma y color:SolidPeso molecular:454.53mSIRK
CAS:mSIRK (G-Protein βγ Binding Peptide) is an ERK1 and ERK2 dual activator that promotes alpha-subunit dissociation.Fórmula:C93H150N20O25Pureza:99.26%Forma y color:SolidPeso molecular:1948.31KRas G12C inhibitor 4
CAS:KRas G12C inhibitor 4 is a compound that inhibits KRas G12C.Fórmula:C33H38ClN7O2Pureza:98%Forma y color:SolidPeso molecular:600.15KRAS G12C inhibitor 45
CAS:KRAS G12C inhibitor 45 is a potent KRAS G12C inhibitor .Fórmula:C32H33F2N5O5SForma y color:SolidPeso molecular:637.7HPK1-IN-25
CAS:HPK1-IN-25, an HPK1 inhibitor, IC50 129 nM, may aid cancer research.Fórmula:C23H25N5OForma y color:SolidPeso molecular:387.48(2Z,3Z)-U0126
CAS:U0126 selectively inhibits MEK1/2, blocks MAPK/ERK signaling, and suppresses Ki-ras-induced cell growth, with IC50s of 72 nM and 58 nM for MEK1/2.Fórmula:C18H16N6S2Forma y color:SolidPeso molecular:380.49KRAS inhibitor-7
CAS:<p>KRAS inhibitor-7 is a potent KRAS G12C inhibitor.</p>Fórmula:C26H27ClF2N6O2Pureza:98%Forma y color:SolidPeso molecular:528.98
