MAPK
Las MAPK son una familia de quinasas de proteínas involucradas en una variedad de procesos celulares, incluyendo crecimiento, proliferación, diferenciación y respuestas al estrés. La vía de señalización MAPK consta de varios niveles, incluidos ERK, JNK y p38 MAPK, cada uno con roles distintos en la función celular. La desregulación de la señalización MAPK está vinculada al cáncer, las enfermedades inflamatorias y los trastornos metabólicos. En CymitQuimica, ofrecemos una amplia gama de inhibidores y activadores de MAPK para apoyar su investigación en biología celular, transducción de señales y mecanismos de enfermedades.
Se han encontrado 893 productos de "MAPK"
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p38 Kinase inhibitor 4
CAS:Compound 135, also known as p38 Kinase Inhibitor 4, is a potent inhibitor of p38 [1].Fórmula:C12H9Cl2N3OPureza:98%Forma y color:SolidPeso molecular:282.13B-Raf IN 16
CAS:<p>B-Raf IN 16, a BRAF inhibitor, belongs to cyclic iminopyrimidine derivatives and can be used for cancer or tumour research.</p>Fórmula:C20H19N5O3SPureza:99.31% - 99.78%Forma y color:SolidPeso molecular:409.46GNE 220
CAS:GNE-220 is a potent and selective inhibitor of MAP4K4 (IC50: 7 nM).Fórmula:C25H26N8Pureza:98%Forma y color:SolidPeso molecular:438.53HPK1-IN-12
CAS:HPK1-IN-12 is a potent inhibitor of HPK1. HPK1-IN-12 has potential for the study of HPK1-related diseases.Fórmula:C25H24FN5O2Forma y color:SolidPeso molecular:445.49XRP44X
CAS:XRP44X (XRP 44X) is a potent inhibitor of Ras-Net (Elk-3) pathway.Fórmula:C21H21ClN4OPureza:99.67%Forma y color:SolidPeso molecular:380.87MNK inhibitor 9
CAS:<p>MNK inhibitor 9 potently blocks MNK1/2 (IC50: 0.003 µM each), is cell-permeable, and useful for tumor research.</p>Fórmula:C25H29N9OForma y color:SolidPeso molecular:471.56KRAS inhibitor-11
KRAS inhibitor-11 is a KRAS inhibitor .Fórmula:C29H47N9O6Forma y color:SolidPeso molecular:617.74RO4927350
CAS:RO4927350 is a potent, selective MEK1/2 inhibitor, blocking MAPK pathway in vitro/vivo and showing notable antitumor effects.Fórmula:C27H28N4O6SForma y color:SolidPeso molecular:536.6ERK1/2 inhibitor 9
CAS:ERK1/2 Inhibitor 9 (Probe 1), a covalent antagonist of ERK1/2, exhibits sub-micromolar efficacy in cellular assays (A375 GI50=0.47 μM) and facilitates theFórmula:C31H32ClN7O3Pureza:98%Forma y color:SolidPeso molecular:586.08GSK1790627
CAS:GSK1790627, the N-deacetylated metabolite of Trametinib, represents an orally active MEK inhibitor that promotes autophagy and triggers apoptosis [1].Fórmula:C24H21FIN5O3Forma y color:SolidPeso molecular:573.36RAF mutant-IN-1
CAS:RAF mutant-IN-1 is an inhibitor of RAF kinase(IC50 values of 21 nM, 30 nM and 392 nM for C-RAF 340D/Y341D, B-RAFV600E and B-RAFWT, respectively).Fórmula:C23H18Cl3FN6O2SPureza:98%Forma y color:SolidPeso molecular:567.85ERK Inhibitor II (Negative control)
CAS:ERK Inhibitor II, a control, blocks ERK and insulin receptor activation, aiding diabetes research.Fórmula:C18H12N6OForma y color:SolidPeso molecular:328.33AZD4747
CAS:<p>AZD4747 is an inhibitor of the mutant GTPase KRASG12C that hasial antitumor activity for the study of pancreatic and colorectal adenocarcinoma.</p>Fórmula:C24H22ClFN2O3Pureza:99.36%Forma y color:SolidPeso molecular:440.89KRAS G12C inhibitor 14
CAS:KRAS G12C inhibitor 14 is a potent KRAS G12C inhibitor with an IC 50 of 18 nM [1].Fórmula:C24H19ClF2N4O3Pureza:98%Forma y color:SolidPeso molecular:484.88Raf inhibitor 3
CAS:Raf inhibitor 3 (Example 30), a potent inhibitor of both B-Raf and C-Raf, exhibits IC50 values below 15 nM. It is applicable in cancer research studies [1].Fórmula:C18H19FN8O2SPureza:98%Forma y color:SolidPeso molecular:430.46KRAS G12C inhibitor 13
CAS:<p>KRAS G12C inhibitor 13 is a KRAS G12C inhibitor .</p>Fórmula:C40H46F3N7O4Pureza:98%Forma y color:SolidPeso molecular:745.83RPR203494
CAS:RPR203494 is a pyrimidine analogue of the p38 inhibitor RPR200765A with an improved in vitro potency.Fórmula:C26H29FN6O4Forma y color:SolidPeso molecular:508.54HPK1-IN-37
CAS:HPK1-IN-37 (compound A85), with an IC50 value of 3.7 nM, is a potent inhibitor of HPK1.Fórmula:C27H35N7O4Forma y color:SolidPeso molecular:521.61PROTAC KRAS G12C degrader-3
CAS:PROTAC KRAS G12C Degrader-3 (Comp 283) serves as a potent degrader of KRAS G12C, utilized in cancer research [1].Fórmula:C63H75ClN14O6Pureza:98%Forma y color:SolidPeso molecular:1159.81ERK1/2 inhibitor 8
CAS:ERK1/2 inhibitor 8 is a potent inhibitor of ERK that acts on ERK2 (IC50: 0.48 nM).Fórmula:C23H20ClN7O2SForma y color:SolidPeso molecular:493.97
