MAPK

Las MAPK son una familia de quinasas de proteínas involucradas en una variedad de procesos celulares, incluyendo crecimiento, proliferación, diferenciación y respuestas al estrés. La vía de señalización MAPK consta de varios niveles, incluidos ERK, JNK y p38 MAPK, cada uno con roles distintos en la función celular. La desregulación de la señalización MAPK está vinculada al cáncer, las enfermedades inflamatorias y los trastornos metabólicos. En CymitQuimica, ofrecemos una amplia gama de inhibidores y activadores de MAPK para apoyar su investigación en biología celular, transducción de señales y mecanismos de enfermedades.

Se han encontrado 894 productos de "MAPK"

Pureza (%)

100

productos por página.

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HPK1-IN-4
CAS:
- 2739844-28-9
<p>HPK1-IN-4 is an HPK1 (MAPK41) inhibitor with an IC 50 of 0.061 nM. HPK1-IN-4 is often used as a preclinical immunotherapy tool compound.</p>
Fórmula:C₂₃H₂₆N₆O₃
Pureza:97.2%
Forma y color:Solid
Peso molecular:434.49
Ref: TM-T40350
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Olomoucine
CAS:
- 101622-51-9
<p>Olomoucine hinders Cdk2, Cdc2, CDK5, ERK1, regulates the cell cycle, and fights melanoma; IC50s: 3-25 µM.</p>
Fórmula:C₁₅H₁₈N₆O
Pureza:99.77%
Forma y color:White Crystalline Powder
Peso molecular:298.34
Ref: TM-T21588
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L-JNKI-1
L-JNKI-1 is a cell-permeable peptide inhibitor specific for JNK, it has been shown to effectively inhibit JNK activity in in vivo studies.
Fórmula:C₁₆₄H₂₈₆N₆₆O₄₀
Pureza:98%
Forma y color:Solid
Peso molecular:3822.44
Ref: TM-TP1353
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TAK1-IN-3
CAS:
- 494772-87-1
TAK1-IN-3 is a novel ATP-competitive TAK1 inhibitor for the study of cancer.
Fórmula:C₁₆H₁₉N₃O₂S
Pureza:98.88%
Forma y color:Solid
Peso molecular:317.41
Ref: TM-T40577
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S6K1-IN-DG2
CAS:
- 871340-88-4
S6K1-IN-DG2(S6K1InhibitorDG2) is a potent p70S6K inhibitor with an IC50 value of less than 100 nM.
Fórmula:C₁₆H₁₇BrN₆O
Pureza:99.99%
Forma y color:Solid
Peso molecular:389.25
Ref: TM-T28652
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Enniatin B1
CAS:
- 19914-20-6
Enniatin B1, a Fusarium mycotoxin, crosses the blood-brain barrier and modulates ERK, NF-κB, and ACAT with an IC50 of 73 μM.
Fórmula:C₃₄H₅₉N₃O₉
Pureza:98%
Forma y color:Solid
Peso molecular:653.858
Ref: TM-T13680
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LC-2
CAS:
- 2502156-03-6
LC-2 (PROTAC KRASG12C Degrader-LC-2) is a novel von Hippel-Lindau-based PROTAC degrader of endogenous KRAS G12C with a DC50 between 0.25 and 0.76 μM.LC-2 is a
Fórmula:C₅₉H₇₁ClFN₁₁O₇S
Pureza:98%
Forma y color:Solid
Peso molecular:1132.78
Ref: TM-T36256
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Anti-ERK2 Antibody (5V598)
Anti-ERK2 Antibody (5V598) is a Rabbit antibody targeting ERK2. Anti-ERK2 Antibody (5V598) can be used in ELISA.
Forma y color:Odour Liquid
Ref: TM-TMAY-00112
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Anti-ERK2 Antibody (4F551)
Anti-ERK2 Antibody (4F551) is a Rabbit antibody targeting ERK2. Anti-ERK2 Antibody (4F551) can be used in ELISA,FCM.
Forma y color:Odour Liquid
Ref: TM-TMAY-00113
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Anti-ERK2 Antibody (9C922)
Anti-ERK2 Antibody (9C922) is a Mouse antibody targeting ERK2. Anti-ERK2 Antibody (9C922) can be used in WB,ELISA.
Forma y color:Odour Liquid
Ref: TM-TMAY-00111
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Enniatin B
CAS:
- 917-13-5
Enniatins B decreases the activation of ERK (p44/p42).
Fórmula:C₃₃H₅₇N₃O₉
Pureza:98%
Forma y color:Solid
Peso molecular:639.831
Ref: TM-T13679
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Tunlametinib
CAS:
- 1801756-06-8
Tunlametinib is a MEK1/2 inhibitor (IC50=1.9 nM) for treating RAS/RAF-driven cancers.
Fórmula:C₁₆H₁₂F₂IN₃O₃S
Pureza:98.72%
Forma y color:Solid
Peso molecular:491.25
Ref: TM-T39220
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CE3F4 analog 1
CAS:
- 2141967-43-1
CE3F4 analog 1 is an analogue of CE3F4.
Fórmula:C₁₁H₉Br₃FNO
Forma y color:Solid
Peso molecular:429.909
Ref: TM-T39606
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RAS GTPase inhibitor 1
CAS:
- 2252242-32-1
RAS GTPase inhibitor 1 is a RAS GTPase inhibitor with potential antitumor activity.
Fórmula:C₂₇H₂₈ClF₄N₅O₂
Pureza:98.43%
Forma y color:Solid
Peso molecular:565.99
Ref: TM-T12692
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Cephradine (Standard)
CAS:
- 38821-53-3
Cephradine (Standard) is the standard substance of Cephradine, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Cephradine (Anspor) is a beta-lactam, first-generation cephalosporin antibiotic with bactericidal activity.
Fórmula:C₁₆H₁₉N₃O₄S
Peso molecular:349.40
Ref: TM-TMSM-0677
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TRPM4 inhibitor 8
CAS:
- 1353979-43-7
TRPM4 inhibitor 8 is an inhibitor of Transient receptor potential melastatin 4(TRPM4) which contributes to viability, migration, cell cycle shift, and adhesion.
Fórmula:C₁₁H₁₇BrN₂
Pureza:99.84%
Forma y color:Solid
Peso molecular:257.17
Ref: TM-T9776
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JH295
CAS:
- 1311143-71-1
JH295: potent, selective Nek2 inhibitor (IC50 = 770 nM), irreversibly targets Cys22, no effect on Cdk1, Aurora B, Plk1, or spindle mechanisms.
Fórmula:C₁₈H₁₆N₄O₂
Forma y color:Solid
Peso molecular:320.352
Ref: TM-T38710
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MLK-IN-1
CAS:
- 1627729-62-7
MLK-IN-1 is a potent and selective mixed-lineage kinase 3 (MLK-3) inhibitor, showing excellent brain penetration and high specificity for MLK-3. MLK-IN-1 at 100 nM supports sustained axonogenesis in cultures challenged with HIV-1 Tat-activated microglia and protects neuronal cells from Tat-induced damage, establishing it as a valuable probe for neuroinflammation and neurodegeneration research.
Fórmula:C₂₃H₂₀N₄O₃S
Pureza:99.74%
Forma y color:Solid
Peso molecular:432.5
Ref: TM-T39102
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Deltarasin HCl
CAS:
- 1440898-82-7
Deltarasin hinders KRAS-PDEδ, impairs cancer cell growth via a PDEδ pocket, disrupting RAS/RAF signaling and autophagy.
Fórmula:C₄₀H₃₇N₅O·xHCl
Forma y color:Solid
Peso molecular:713.144
Ref: TM-T70646
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L-779450
CAS:
- 303727-31-3
L-779450, an effective, ATP-competitive Raf kinase inhibitor (IC50: 10 nM) , displays >7, >30 and >70-fold selectivity over p38α, GSK3β and Lck respectively.
Fórmula:C₂₀H₁₄ClN₃O
Pureza:≥95%
Forma y color:Solid
Peso molecular:347.8
Ref: TM-T1953