MAPK
Las MAPK son una familia de quinasas de proteínas involucradas en una variedad de procesos celulares, incluyendo crecimiento, proliferación, diferenciación y respuestas al estrés. La vía de señalización MAPK consta de varios niveles, incluidos ERK, JNK y p38 MAPK, cada uno con roles distintos en la función celular. La desregulación de la señalización MAPK está vinculada al cáncer, las enfermedades inflamatorias y los trastornos metabólicos. En CymitQuimica, ofrecemos una amplia gama de inhibidores y activadores de MAPK para apoyar su investigación en biología celular, transducción de señales y mecanismos de enfermedades.
Se han encontrado 894 productos de "MAPK"
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
Locostatin
CAS:Locostatin is a potent and cell permeable inhibitor of Raf kinase inhibitor protein (RKIP)/Raf1 kinase interaction and an inhibitor of cell migration.Fórmula:C14H15NO3Pureza:97.13%Forma y color:SolidPeso molecular:245.271588-A4
CAS:1588-A4 (ARS-1620 Intermediate) is an intermediate of ARS-1620 which is an atropisomeric selective KRASG12C inhibitor with desirable pharmacokinetics.Fórmula:C17H19BrClFN4O2Pureza:98.59%Forma y color:SolidPeso molecular:445.71PLX-4720
CAS:PLX-4720 is a potent and selective B-Raf (V600E) inhibitor designed to block the ATP-binding site of oncogenic B-Raf.Cost-effective and quality-assured.Fórmula:C17H14ClF2N3O3SPureza:97.78% - 99.83%Forma y color:SolidPeso molecular:413.83BI-D1870
CAS:BI-D1870 is a highly specific, blood-brain-permeable, and ATP-competitive inhibitor of the N-terminal AGC kinase domain of RSK.Cost-effective and quality-assured.Fórmula:C19H23F2N5O2Pureza:98.51% - 99.43%Forma y color:SolidPeso molecular:391.42Deltarasin HCl
CAS:Deltarasin hinders KRAS-PDEδ, impairs cancer cell growth via a PDEδ pocket, disrupting RAS/RAF signaling and autophagy.Fórmula:C40H37N5O·xHClForma y color:SolidPeso molecular:713.144Bentamapimod
CAS:<p>Bentamapimod (AS 602801) is a novel, orally active inhibitor of JNK.</p>Fórmula:C25H23N5O2SPureza:97.04% - 99.92%Forma y color:SolidPeso molecular:457.55Varenicline Tartrate
CAS:<p>Varenicline Tartrate (CP 526555-18) is a benzazepine derivative that functions as an ALPHA4/BETA2 NICOTINIC RECEPTOR partial agonist.</p>Fórmula:C13H13N3·C4H6O6Pureza:98.23% - 98.32%Forma y color:Tan SolidPeso molecular:361.35I-49 free base
I-49 free base (Pyrido[4,3-d]pyrimidin-7(6H)-one, 2-methyl-4-[[(1R)-1-[2-methyl-3-(trifluoromethyl)phenyl]ethyl]amino]-6-(tetrahydro-2H-pyran-4-yl)-) is a novelFórmula:C23H26ClF3N4O2Pureza:99.64% - 99.88%Forma y color:SolidPeso molecular:482.92Pimasertib HCl
CAS:Pimasertib HCl, an oral MEK1/2 inhibitor, may thwart tumor growth by blocking RAS/RAF/MEK/ERK signaling.Fórmula:C15H16ClFIN3O3Forma y color:SolidPeso molecular:467.66TAK-733
CAS:TAK-733 is an orally bioavailable small-molecule inhibitor of MEK1 and MEK2 (MEK1/2) with potential antineoplastic activity.Fórmula:C17H15F2IN4O4Pureza:98.31% - 99.53%Forma y color:SolidPeso molecular:504.23Adagrasib
CAS:<p>View and buy Adagrasib (MRTX849) from TargetMol.MRTX849 is a potent, selective and covalent KRASG12C inhibitor with potential antineoplastic activity. Cited in 2 publications.</p>Fórmula:C32H35ClFN7O2Pureza:99.10% - 99.9%Forma y color:SolidPeso molecular:604.12K-Ras(G12C) inhibitor 9
CAS:K-Ras(G12C) inhibitor 9 is an allosteric inhibitor of oncogenic K-Ras(G12C).Fórmula:C16H21ClIN3O4SPureza:97.33% - 97.45%Forma y color:SolidPeso molecular:513.78Encorafenib
CAS:Encorafenib (LGX818) is an orally available mutated BRaf V600E inhibitor(IC50=0.3 nM) with potential antineoplastic activity.Fórmula:C22H27ClFN7O4SPureza:99.51% - 99.83%Forma y color:SolidPeso molecular:540.01JNK Inhibitor VIII
CAS:<p>JNK Inhibitor VIII (TCS JNK 6o) is an ATP-competitive selective inhibitor of c-Jun N-terminal kinase (JNK)(IC50 values of 45 nM and 160 nM for JNK-1 and -2,</p>Fórmula:C18H20N4O4Pureza:98.93%Forma y color:SolidPeso molecular:356.38HPK1-IN-34
CAS:HPK1-IN-34 (Compound 143) is an inhibitor of HPK1 (Haematopoietic progenitor kinase 1) with an IC₅₀ < 0.1 μM, suitable for cancer and immunology research.Fórmula:C25H28N4O2SPureza:99.39%Forma y color:SolidPeso molecular:448.58PF-06260933
CAS:<p>PF-06260933 is a highly selective small-molecule MAP4K4 inhibitor with IC50s of 3.7 and 160 nM for kinase and cell, respectively.</p>Fórmula:C16H13ClN4Pureza:99.63% - 99.97%Forma y color:SolidPeso molecular:296.75β-Glycerophosphate disodium salt pentahydrate
CAS:β-Glycerophosphate disodium salt pentahydrate is a protein phosphatase inhibitor.Fórmula:C3H7O6PH2ONaPureza:98.94% - ≥98%Forma y color:SolidPeso molecular:306.11Cefotetan
CAS:Cefotetan, a cephamycin antibiotic, fights various bacteria by disrupting cell wall synthesis.Fórmula:C17H17N7O8S4Pureza:95.72% - 99.38%Forma y color:SolidPeso molecular:575.62MRTX1133
CAS:<p>View and buy MRTX1133 from TargetMol.MRTX1133 is a potent, selective, and noncovalent inhibitor of KRAS G12D.</p>Fórmula:C33H31F3N6O2Pureza:97.39% - 99.6%Forma y color:SolidPeso molecular:600.63GSK-114
CAS:GSK-114, a TNNI3K inhibitor with a 25 nM IC50, is 40x more selective than B-Raf and good for in vivo studies.Fórmula:C19H23N5O4SPureza:99.51%Forma y color:SolidPeso molecular:417.48
