ERK
Se han encontrado 204 productos de "ERK"
Omtriptolide
CAS:Omtriptolide, triptolide purified from the Chinese herb, is a water-soluble derivative prodrug.Fórmula:C24H28O9Pureza:98%Forma y color:SolidPeso molecular:460.479Ravoxertinib hydrochloride
CAS:Ravoxertinib hydrochloride is an orally bioavailable and selective inhibitor for ERK kinase activity (IC50: 6.1 nM and 3.1 nM for ERK1 and ERK2, respectively).Fórmula:C21H19Cl2FN6O2Pureza:98%Forma y color:SolidPeso molecular:477.32Pamoic acid
CAS:Pamoic acid is the orphan G protein-coupled receptor GPR35 agonist. Pamoic acid activates ERK and beta-arrestin2 and causes antinociceptive activity.
Fórmula:C23H16O6Pureza:99.99%Forma y color:Fine Yellow PowderPeso molecular:388.37WQ-C-401
CAS:WQ-C-401 is an orally active inhibitor of the platelet-derived growth factor receptor (PDGFR). It inhibits cell proliferation by blocking PDGFR auto-phosphorylation in a concentration-dependent manner, with EC50 values of 3.5 nM for PDGFRαY849 and 5.8 nM for PDGFRβY1021. Additionally, WQ-C-401 suppresses the proliferation and migration of PASMCs by inhibiting PDGF-BB-induced phosphorylation of ERK1/2, reduces collagen I synthesis, and increases α-SMA expression, thereby preventing pulmonary vascular remodeling. This compound shows promise for research in the field of pulmonary arterial hypertension.
Fórmula:C24H26N4O3Forma y color:SolidPeso molecular:418.49Ref: TM-T200766
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