ERK
ERK es una proteína clave en la vía de señalización MAPK (Mitogen-Activated Protein Kinase), que está involucrada en la transmisión de señales desde los receptores de la superficie celular hasta el ADN en el núcleo celular. ERK juega un papel crucial en la regulación de varios procesos celulares, incluyendo la proliferación, diferenciación y supervivencia. La desregulación de la señalización ERK está asociada con el desarrollo de cáncer y otras enfermedades, lo que la convierte en un objetivo importante para la intervención terapéutica. En CymitQuimica, ofrecemos una selección de inhibidores y moduladores de ERK de alta calidad para apoyar su investigación en señalización celular, oncología y desarrollo terapéutico.
Se han encontrado 193 productos de "ERK"
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Edaxeterkib
CAS:<p>Edaxeterkib is a potent extracellular signal- regulated kinase (ERK) inhibitor for the research of cancer.</p>Fórmula:C26H27N7O2Forma y color:SolidPeso molecular:469.549GSK143
CAS:<p>GSK143: Oral SYK inhibitor, pIC50=7.5, curbs pErk, anti-inflammatory, hinders immune cells in mice.</p>Fórmula:C17H22N6O2Forma y color:SolidPeso molecular:342.403PD 198306
CAS:<p>PD 198306: a MEK inhibitor with antihyperalgesic properties, reduces Streptozocin-boosted active ERK1.</p>Fórmula:C18H16F3IN2O2Pureza:99.66%Forma y color:SolidPeso molecular:476.23Fulipiftide
CAS:<p>Fulipiftide is a short peptide derived from pigment epithelium-derived factor (PEDF). It stimulates the amplification of nuclear stem cell factor+TSPC by activating the ERK2 and STAT3 signaling pathways. Fulipiftide also exhibits anti-inflammatory properties and is applicable in research on acute tendon injuries.</p>Fórmula:C144H227N41O47Forma y color:SolidPeso molecular:3284.59MAPK Inhibitor Library
<p>A unique collection of 365 compounds targeting MAPK signaling for drug discovery in MAPK related diseases;</p>Forma y color:Odour SolidAnti-inflammatory agent 35
CAS:<p>Anti-inflammatory agent 35 is a potent anti-inflammatory agent.</p>Fórmula:C27H29NO8Pureza:99.98%Forma y color:SoildPeso molecular:495.52ROCK-IN-5
CAS:<p>ROCK-IN-5 (I-B-37) inhibits kinases like ROCK/ERK/GSK; may aid in cardiac and neuro disease studies.</p>Fórmula:C16H11ClFN3OSPureza:99.72% - 99.83%Forma y color:SolidPeso molecular:347.79VSLRGDTRG acetate
<p>VSLRGDTRG acetate is a synthetic peptide of the RGD motif from cadherin17 (CDH17), capable of binding to α2β1 integrin and activating its signaling pathways. It facilitates the high-affinity conformational change of β1 integrin via the RGD motif, enhancing cell adhesion and phosphorylation of FAK and ERK1/2, thereby promoting tumor proliferation and metastasis. VSLRGDTRG acetate is applicable in research on cancers expressing CDH17, such as colon and pancreatic cancers.</p>Forma y color:Odour SolidPPM-3
<p>PPM-3, a selective PROTAC ERK5 degrader, exhibits a potent inhibitory concentration (IC 50) of 62.4 nM.</p>Fórmula:C54H69N11O6SPureza:98%Forma y color:SolidPeso molecular:1000.26EphB2 Protein, Mouse, Recombinant (hFc)
EphB2 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.Forma y color:Lyophilized PowderPeso molecular:84.6 kDa (predicted); 96.6 kDa (reducing conditions)ERK2 Protein, Human, Recombinant (GST)
<p>ERK2 Protein, Human, Recombinant (GST) is expressed in Baculovirus insect cells with GST tag.</p>Forma y color:Lyophilized PowderPeso molecular:67 kDa (predicted); 67 kDa (reducing conditions)EphB2 Protein, Human, Recombinant (His)
EphB2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.Forma y color:Lyophilized PowderPeso molecular:59.2 kDa (predicted); 65-75 kDa (reducing condition, due to glycosylation)EphB2 Protein, Mouse, Recombinant (His)
<p>EphB2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.</p>Forma y color:Lyophilized PowderPeso molecular:59.3 kDa (predicted); 65 kDa (reducing conditions)PERK-IN-2
CAS:<p>PERK-IN-2 is a potent inhibitor of PERK(IC50 of 0.2 nM).</p>Fórmula:C23H18F3N5OPureza:98%Forma y color:SolidPeso molecular:437.42ERα degrader-2
CAS:ERα degrader-2 is an estrogen receptor (SERD) degrader with anticancer activity that inhibits ERα for the prevention and treatment of HER-positive breast cancFórmula:C29H27F3N2O2Pureza:99.71%Forma y color:SolidPeso molecular:492.53TRPM4 inhibitor 8
CAS:<p>TRPM4 inhibitor 8 is an inhibitor of Transient receptor potential melastatin 4(TRPM4) which contributes to viability, migration, cell cycle shift, and adhesion.</p>Fórmula:C11H17BrN2Pureza:97%Forma y color:SolidPeso molecular:257.17EphB2 Protein, Human, Recombinant (His & hFc)
<p>EphB2 Protein, Human, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag.</p>Forma y color:Lyophilized PowderPeso molecular:86 kDa (predicted); 90-100 kDa (reducing condition, due to glycosylation)Pamoic acid disodium
CAS:Pamoic acid disodium is a GPR35 agonist.Fórmula:C23H16NaO6Pureza:99.73%Forma y color:Yellow PowderPeso molecular:411.36EM127
CAS:<p>EM127: covalent SMYD3 inhibitor, KD 13μM, impedes ERK1/2, hinders SMYD3 gene regulation, long-term methyltransferase reduction, potential in cancer study.</p>Fórmula:C14H18ClN3O3Pureza:97.61%Forma y color:SolidPeso molecular:311.76ERK2 Protein, Mouse, Recombinant (His & GST)
<p>ERK2 Protein, Mouse, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag.</p>Forma y color:Lyophilized PowderPeso molecular:69.1 kDa (predicted); 60 kDa (reducing conditions)
