p38 MAPK
Las p38 MAPK son un subgrupo de MAPK que responden a señales de estrés y están involucradas en la regulación de la inflamación, la diferenciación celular, la apoptosis y la autofagia. La señalización de p38 MAPK es crucial en las respuestas inmunitarias y está implicada en varias enfermedades, incluidas las condiciones inflamatorias crónicas, el cáncer y los trastornos neurodegenerativos. En CymitQuimica, ofrecemos una gama completa de inhibidores y moduladores de p38 MAPK para apoyar su investigación en inflamación, respuesta al estrés y desarrollo terapéutico.
Se han encontrado 129 productos para "p38 MAPK".
Filtrar por
Porcentaje de pureza
0
100
|
0
|
50
|
90
|
95
|
100
- Precio más bajo
- Precio más alto
- Pureza más baja
- Pureza más alta
- Entrega estimada más rápida
Carbimazole
CAS:Carbimazole, an imidazolium-based thyroid blocker, turns to MMI in the body. Used in Graves' disease research.Fórmula:C7H10N2O2SPureza:99.98%Forma y color:White SolidPeso molecular:186.23Hesperetin
CAS:Hesperetin belongs to the flavanone class of flavonoids.Fórmula:C16H14O6Pureza:98.45% - 99.27%Forma y color:SolidPeso molecular:302.28BI-3406
CAS:BI-3406 is an orally active, highly potent and selective between KRAS and Son of Sevenless 1 (SOS1) interaction inhibitor(IC50 : 6 nM),with anticancer activity.Fórmula:C23H25F3N4O3Pureza:99.2% - 99.66%Forma y color:SolidPeso molecular:462.4648Oxidopamine hydrobromide
CAS:Oxidopamine hydrobromide (6-OHDA hydrobromide) is a neurotransmitter dopamine antagonist.Fórmula:C8H12BrNO3Pureza:98.59% - 99.88%Forma y color:Brown SolidPeso molecular:250.09Aspirin
CAS:Aspirin (Acetylsalicylic Acid) is a COX inhibitor. Aspirin has anti-inflammatory, antipyretic and analgesic activities. Cost-effective and quality-assured.Fórmula:C9H8O4Pureza:99.78% - 99.91%Forma y color:SolidPeso molecular:180.1574AZD7624
CAS:AZD7624 is an p38 inhibitor. It has potent anti-inflammatory activity.Fórmula:C27H30FN5O3Pureza:98.82%Forma y color:White SolidPeso molecular:491.5572Dehydrocorydaline chloride
CAS:Dehydrocorydaline chloride (13-Methylpalmatine chloride) is an alkaloid with anti-inflammatory and anti-cancer activity. Can improve the activation of p38 MAPK.Fórmula:C22H24ClNO4Pureza:99.53%Forma y color:SolidPeso molecular:401.883Ro-3201195
CAS:Ro-3201195 is a novel orally available p38 MAPK inhibitor with high selectivity.Fórmula:C19H18FN3O4Pureza:99.84%Forma y color:SolidPeso molecular:371.3623SB220025
CAS:SB220025 is a P38 mitogen-activated protein kinase inhibitor that inhibits p56Lck and PKC, and inhibits angiogenesis.Fórmula:C18H19FN6Pureza:99.97%Forma y color:White SolidPeso molecular:338.3821Dilmapimod
CAS:Dilmapimod (SB-681323) is a potent inhibitor of p38 MAPK ,it potentially suppresses inflammation in chronic obstructive pulmonary disease.Fórmula:C23H19F3N4O3Pureza:97.53%Forma y color:White SolidPeso molecular:456.4172PF-3644022
CAS:PF-3644022 is a selective MK2 inhibitor, effective against TNFα (IC50: 5.2 nM, Ki: 3 nM), with anti-inflammatory properties. Also blocks MK3 and PRAK.Fórmula:C21H18N4OSPureza:98.13%Forma y color:SolidPeso molecular:374.46Oxidopamine hydrochloride
CAS:Oxidopamine hydrochloride (6-Hydroxydopamine hydrochloride) is an neurotransmitter dopamine antagonist.Fórmula:C8H12ClNO3Pureza:98.34% - 99.85%Forma y color:White SolidPeso molecular:205.639LXH254
CAS:LXH254 is a B/C RAF inhibitor with IC50 values of 0.2 nM and 0.07 nM for inhibiting BRAF and CRAF.Cost-effective and quality-assured.Fórmula:C25H25F3N4O4Pureza:98.30% - 99.92%Forma y color:White SolidPeso molecular:502.4856NR-11c
NR-11c is a selective and potent p38α PROTAC degrader. It effectively degrades p38α in various tumor cells. When administered to mice via intraperitoneal or tail vein injection, NR-11c primarily acts in the liver. It is used for cancer research.Fórmula:C59H71BrF2N10O8SForma y color:SolidPeso molecular:1198.22Klotho-derived peptide 1 hydrochloride
Klotho-derived peptide 1 (KP1 human) hydrochloride inhibits the interaction between TGF-β and TGF-β receptor 2, suppressing the activation of TGF-β-induced Smad2/3 and mitogen-activated protein kinase (MAPK). Additionally, it exhibits antifibrotic and renal protective effects in mouse models.Forma y color:Odour SolidCyclotraxin B
CAS:TrkB receptor antagonist; inhibits BDNF-TrkB signaling (IC50 = 0.30 nM); alters receptor shape; may reduce anxiety in mice.Fórmula:C48H73N13O17S3Pureza:98%Forma y color:SolidPeso molecular:1200.36MAP3K5-IN-1
CAS:Compound 7, also known as 3′-O-Demethyl-4′-N-demethyl-4′-N-acetyl-4′-epi-staurosporine, serves as an inhibitor of protein kinases, displaying IC50 values of 0.092 μM for PKC-α, 0.26 μM for ROCK, and 0.77 μM for ASK1. Additionally, this compound exhibits significant cytotoxicity towards PC-3 cancer cells, with an IC50 of 0.16 μM [1].Fórmula:C28H24N4O4Forma y color:SolidPeso molecular:480.51p38 MAP Kinase Inhibitor Ⅵ
CAS:p38 MAP Kinase Inhibitor Ⅵ is a potent p38 MAP Kinase inhibitor with anti-inflammatory activity.Fórmula:C16H13FN2OS2Pureza:98.53%Forma y color:Yellow SolidPeso molecular:332.416PDE4-IN-26
PDE4-IN-26 (Compound A5) is an orally active, highly selective inhibitor of PDE4. It exhibits anti-inflammatory properties by inhibiting p38 MAPK phosphorylation. In mouse models of acute lung injury and chronic obstructive pulmonary disease, PDE4-IN-26 reduces lung inflammation, damage, and fibrosis, while promoting sputum secretion and alleviating cough. It is useful for researching lung injury-related diseases.Fórmula:C22H18F2N4O3SForma y color:SolidPeso molecular:456.47DB-10
DB-10 serves as a precursor to 3-nbutylphthalide (NBP). It is absorbed by cells in a temperature and energy-dependent manner through the pyrilamine cation transporter. DB-10 enhances cell survival and rapidly converts into an active form in vivo, increasing accumulation within the brain. This compound is applicable in ischemic stroke research.Forma y color:Odour Solid
