p38 MAPK
Las p38 MAPK son un subgrupo de MAPK que responden a señales de estrés y están involucradas en la regulación de la inflamación, la diferenciación celular, la apoptosis y la autofagia. La señalización de p38 MAPK es crucial en las respuestas inmunitarias y está implicada en varias enfermedades, incluidas las condiciones inflamatorias crónicas, el cáncer y los trastornos neurodegenerativos. En CymitQuimica, ofrecemos una gama completa de inhibidores y moduladores de p38 MAPK para apoyar su investigación en inflamación, respuesta al estrés y desarrollo terapéutico.
Se han encontrado 117 productos de "p38 MAPK"
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Dihydrocaffeic acid
CAS:<p>Dihydrocaffeic acid, a chlorogenic acid metabolite, has antioxidant, anti-Alzheimer's, neuroprotective, and lipid-lowering properties.</p>Fórmula:C9H10O4Pureza:98.63%Forma y color:SolidPeso molecular:182.17Aspirin
CAS:<p>Aspirin (Acetylsalicylic Acid) is a COX inhibitor. Aspirin has anti-inflammatory, antipyretic and analgesic activities. Cost-effective and quality-assured.</p>Fórmula:C9H8O4Pureza:99.78% - 99.91%Forma y color:White Solid CrystallinePeso molecular:180.16PF-3644022
CAS:<p>PF-3644022 is a selective MK2 inhibitor, effective against TNFα (IC50: 5.2 nM, Ki: 3 nM), with anti-inflammatory properties. Also blocks MK3 and PRAK.</p>Fórmula:C21H18N4OSPureza:98.13%Forma y color:SolidPeso molecular:374.46Hesperetin
CAS:<p>Hesperetin belongs to the flavanone class of flavonoids.</p>Fórmula:C16H14O6Pureza:98.45% - 99.27%Forma y color:SolidPeso molecular:302.28Oxidopamine hydrochloride
CAS:<p>Oxidopamine hydrochloride (6-Hydroxydopamine hydrochloride) is an neurotransmitter dopamine antagonist.</p>Fórmula:C8H12ClNO3Pureza:98.34% - 99.85%Forma y color:Physical Description Beige Solid (Ntp 1992)Peso molecular:205.64LXH254
CAS:<p>LXH254 is a B/C RAF inhibitor with IC50 values of 0.2 nM and 0.07 nM for inhibiting BRAF and CRAF.Cost-effective and quality-assured.</p>Fórmula:C25H25F3N4O4Pureza:98.3% - 99.92%Forma y color:SolidPeso molecular:502.49Carbimazole
CAS:<p>Carbimazole, an imidazolium-based thyroid blocker, turns to MMI in the body. Used in Graves' disease research.</p>Fórmula:C7H10N2O2SPureza:99.98%Forma y color:SolidPeso molecular:186.23AZD7624
CAS:<p>AZD7624 is an p38 inhibitor. It has potent anti-inflammatory activity.</p>Fórmula:C27H30FN5O3Pureza:98.82%Forma y color:SolidPeso molecular:491.56Oxidopamine hydrobromide
CAS:<p>Oxidopamine hydrobromide (6-OHDA hydrobromide) is a neurotransmitter dopamine antagonist.</p>Fórmula:C8H12BrNO3Pureza:98.22% - 99.88%Forma y color:Beige To Brown Fine Crystalline PowderPeso molecular:250.09Dilmapimod
CAS:<p>Dilmapimod (SB-681323) is a potent inhibitor of p38 MAPK ,it potentially suppresses inflammation in chronic obstructive pulmonary disease.</p>Fórmula:C23H19F3N4O3Pureza:97.53%Forma y color:SolidPeso molecular:456.42Dehydrocorydaline chloride
CAS:<p>Dehydrocorydaline chloride (13-Methylpalmatine chloride) is an alkaloid with anti-inflammatory and anti-cancer activity. Can improve the activation of p38 MAPK.</p>Fórmula:C22H24ClNO4Pureza:99.53%Forma y color:SolidPeso molecular:401.88BI-3406
CAS:<p>BI-3406 is an orally active, highly potent and selective between KRAS and Son of Sevenless 1 (SOS1) interaction inhibitor(IC50 : 6 nM),with anticancer activity.</p>Fórmula:C23H25F3N4O3Pureza:99.2% - 99.66%Forma y color:SolidPeso molecular:462.46SB220025
CAS:<p>SB220025 is a P38 mitogen-activated protein kinase inhibitor that inhibits p56Lck and PKC, and inhibits angiogenesis.</p>Fórmula:C18H19FN6Pureza:99.44%Forma y color:SolidPeso molecular:338.38p38α inhibitor 3
CAS:<p>p38α inhibitor 3 is a inhibitor of the mitogen-activated protein kinase p38α that can block the effectiveness of myoblast differentiation.</p>Fórmula:C19H20FNOPureza:99.94%Forma y color:SoildPeso molecular:297.37p38 MAP Kinase Inhibitor Ⅵ
CAS:<p>p38 MAP Kinase Inhibitor Ⅵ is a potent p38 MAP Kinase inhibitor with anti-inflammatory activity.</p>Fórmula:C16H13FN2OS2Pureza:98.53%Forma y color:SolidPeso molecular:332.42p38α inhibitor 5
CAS:<p>The compound p38α inhibitor5 (compound 1) is a PROTAC-type ligand that targets p38 and is utilized in the synthesis of NR-11c.</p>Fórmula:C26H23BrF2N2O3Forma y color:SolidPeso molecular:529.37WYE-687
CAS:<p>WYE-687 is a selective mTOR inhibitor (IC50: 7 nM), over 100x more selective for mTOR than PI3Kα/γ, affecting mTORC1/pS6K and mTORC2/P-AKT(S473).</p>Fórmula:C28H32N8O3Pureza:99.93%Forma y color:SolidPeso molecular:528.61Z16078526
CAS:<p>Z16078526 promotes Ucp1, p38 MAPK, lipolysis, thermogenic genes, and mitochondrial activity in mouse brown adipocytes.</p>Fórmula:C18H17N3O4SPureza:98.93%Forma y color:SolidPeso molecular:371.41Talmapimod hydrochloride
CAS:<p>Talmapimod hydrochloride: selective p38α inhibitor, 9 nM IC50, 10x less effective on p38β, >2000-fold selective vs 20+ kinases.</p>Fórmula:C27H31Cl2FN4O3Pureza:98%Forma y color:SolidPeso molecular:549.46PDE4-IN-26
<p>PDE4-IN-26 (Compound A5) is an orally active, highly selective inhibitor of PDE4. It exhibits anti-inflammatory properties by inhibiting p38 MAPK phosphorylation. In mouse models of acute lung injury and chronic obstructive pulmonary disease, PDE4-IN-26 reduces lung inflammation, damage, and fibrosis, while promoting sputum secretion and alleviating cough. It is useful for researching lung injury-related diseases.</p>Fórmula:C22H18F2N4O3SForma y color:SolidPeso molecular:456.47Ro-3201195
CAS:<p>Ro-3201195 is a novel orally available p38 MAPK inhibitor with high selectivity.</p>Fórmula:C19H18FN3O4Pureza:99.15%Forma y color:SolidPeso molecular:371.36Cyclotraxin B
CAS:<p>TrkB receptor antagonist; inhibits BDNF-TrkB signaling (IC50 = 0.30 nM); alters receptor shape; may reduce anxiety in mice.</p>Fórmula:C48H73N13O17S3Pureza:98%Forma y color:SolidPeso molecular:1200.36Esculin sesquihydrate
CAS:<p>Esculin sesquihydrate, a coumarin glucoside with fluorescent properties and a constituent of ash bark, improves cognitive deficits associated with experimental</p>Fórmula:C15H16O9H2OPureza:98%Forma y color:SolidPeso molecular:367.31MAP3K5-IN-1
CAS:<p>Compound 7, also known as 3′-O-Demethyl-4′-N-demethyl-4′-N-acetyl-4′-epi-staurosporine, serves as an inhibitor of protein kinases, displaying IC50 values of 0.092 μM for PKC-α, 0.26 μM for ROCK, and 0.77 μM for ASK1. Additionally, this compound exhibits significant cytotoxicity towards PC-3 cancer cells, with an IC50 of 0.16 μM [1].</p>Fórmula:C28H24N4O4Forma y color:SolidPeso molecular:480.51DB-10
<p>DB-10 serves as a precursor to 3-nbutylphthalide (NBP). It is absorbed by cells in a temperature and energy-dependent manner through the pyrilamine cation transporter. DB-10 enhances cell survival and rapidly converts into an active form in vivo, increasing accumulation within the brain. This compound is applicable in ischemic stroke research.</p>Forma y color:Odour SolidOVA-E1 peptide TFA
CAS:<p>OVA-E1 peptide TFA activates the p38 and JNK cascades similarly in mutant and wild-type thymocytes.</p>Fórmula:C49H77F3N10O16Pureza:98%Forma y color:SolidPeso molecular:1119.19R1487 Hydrochloride
CAS:<p>R1487 Hydrochloride (R1487 (Hydrochloride)) is an orally bioavailable and highly selective inhibitors of p38α.</p>Fórmula:C19H19ClF2N4O3Pureza:99.42%Forma y color:SolidPeso molecular:424.83Kaempferol-3-O-glucorhamnoside
CAS:<p>Kaempferol-3-O-glucorhamnoside (Kaempferol 3-glucorhamnoside), a flavonoid derived from plant Thesium chinense Turcz, inhibits inflammatory responses via MAPK</p>Fórmula:C27H30O15Pureza:96.96% - 98.17%Forma y color:SolidPeso molecular:594.5Neflamapimod
CAS:<p>Neflamapimod (VX-745) , a specific and effective inhibitor of p38α(IC50=10 nM), is 22-fold greater specificity against p38β and no inhibition activity to p38γ.</p>Fórmula:C19H9Cl2F2N3OSPureza:97.88% - 99.75%Forma y color:SolidPeso molecular:436.26Sertaconazole nitrate
CAS:<p>Sertaconazole nitrate, a broad-spectrum topical antifungal, treats skin and mucosal infections.</p>Fórmula:C20H15Cl3N2OS·HNO3Pureza:98.66% - 99.65%Forma y color:SolidPeso molecular:500.78ASK1-IN-1
CAS:<p>ASK1-IN-1 inhibits apoptosis kinase 1, crucial in cell stress responses, with 21 nM IC50.</p>Fórmula:C19H19N9O2Pureza:99.92%Forma y color:SolidPeso molecular:405.41SB 202190
CAS:<p>SB 202190 (FHPI) is a p38 MAPK inhibitor that inhibits p38α and p38β2 (IC50=50/100 nM) selectively and cell-permeably.</p>Fórmula:C20H14FN3OPureza:98% - 99.84%Forma y color:Pale YellowPeso molecular:331.34CK1-IN-1
CAS:<p>CK1-IN-1, a CK1 inhibitor with IC50: 15nM CK1δ, 16nM CK1ε, 73nM p38σ; patent WO2015119579A1.</p>Fórmula:C24H15F2N3Pureza:98.79%Forma y color:SolidPeso molecular:383.39Gypenoside L
CAS:<p>Gypenoside L inhibits autophagic flux and induces cell death in human esophageal cancer cells through endoplasm reticulum stress-mediated Ca2+ release.</p>Fórmula:C42H72O14Pureza:99.42% - 99.65%Forma y color:SolidPeso molecular:801.01UM-164
CAS:<p>UM-164 (DAS-DFGO-II), a highly potent c-Src inhibitor with a dissociation constant (Kd) of 2.7 nM, also effectively inhibits p38α and p38β.</p>Fórmula:C30H31F3N8O3SPureza:98.72% - 99.52%Forma y color:SolidPeso molecular:640.68Adezmapimod
CAS:<p>Adezmapimod (SB 203580) is a p38 MAPK inhibitor (IC50=0.3-0.5 μM) that is selective and ATP-competitive.</p>Fórmula:C21H16FN3OSPureza:99.42% - 99.93%Forma y color:White SolidPeso molecular:377.435,6,7-TRIMETHOXYFLAVONE
CAS:<p>5,6,7-Trimethoxyflavone, a natural product extracted from Japanese Callicarpa, acts as a p38-α MAPK inhibitor and exhibits anti-inflammatory properties.</p>Fórmula:C18H16O5Pureza:99.05% - 99.49%Forma y color:SolidPeso molecular:312.32SD 0006
CAS:<p>SD 0006 (SD-06) is a MAPK p38 alpha inhibitor( IC50 : 110 nM) for the treatment of arthritis.</p>Fórmula:C20H20ClN5O2Pureza:98.32%Forma y color:SolidPeso molecular:397.86Nitidine chloride
CAS:<p>1.</p>Fórmula:C21H18ClNO4Pureza:96.59% - 98.91%Forma y color:SolidPeso molecular:383.82SB 239063
CAS:<p>SB 239063 (SB239063) is a potent and selective p38 MAPKα/β inhibitor with IC50 of 44 nM, showing no activity against the γ- and δ-kinase isoforms.</p>Fórmula:C20H21FN4O2Pureza:99.42% - 99.81%Forma y color:SolidPeso molecular:368.4Rotundic acid
CAS:<p>Rotundic acid fights various cancers: HepG2, A375, NCI-H446, MCF-7, and HT-29.</p>Fórmula:C30H48O5Pureza:96.91% - 99.97%Forma y color:SolidPeso molecular:488.7Cornuside
CAS:<p>Cornuside boosts immunity, reduces inflammation, protects heart and liver, and guards against brain injury by modulating stress responses.</p>Fórmula:C24H30O14Pureza:99.86% - >99.99%Forma y color:SolidPeso molecular:542.49Andrograpanin
CAS:<p>Andrograpanin (19-HYDROXY-8(17),13-LABDADIEN-16,15-OLIDE) is a bioactive compound from Andrographis paniculata.</p>Fórmula:C20H30O3Pureza:99.03% - 99.457%Forma y color:SolidPeso molecular:318.45FERULIC ACID METHYL ESTER
CAS:<p>FERULIC ACID METHYL ESTER (Methyl ferulate) is a hydroxycinnamic acid that is abundant in plants. FERULIC ACID METHYL ESTER has antioxidant activities.</p>Fórmula:C11H12O4Pureza:99.66% - 99.95%Forma y color:SolidPeso molecular:208.21BMS-582949 hydrochloride
CAS:<p>The BMS-582949 hydrochloride (BMS-582949 HCl) is a highly specific p38α MAPK inhibitor (IC50: 13 nM).</p>Fórmula:C22H27ClN6O2Pureza:97.57% - 98.75%Forma y color:SolidPeso molecular:442.95R1487
CAS:<p>R1487 is an orally bioavailable and highly selective p38α mitogen-activated protein kinase inhibitor.</p>Fórmula:C19H18F2N4O3Pureza:99.77%Forma y color:SolidPeso molecular:388.37SR-318
CAS:<p>SR-318 inhibits TNF-α (IC50=283 nM), selectively targets p38 MAPK: IC50 of 5nM (p38α), 32nM (p38β), 6.11μM (p38α/β).</p>Fórmula:C27H33N5O2Pureza:99.74%Forma y color:SolidPeso molecular:459.58Afatinib Dimaleate
CAS:<p>Afatinib Dimaleate (BIBW 2992MA2) is an orally bioavailable anilino-quinazoline derivative and inhibitor of the EGFR family, with antineoplastic activity.</p>Fórmula:C32H33ClFN5O11Pureza:98.11% - 99.87%Forma y color:SolidPeso molecular:718.08TA-02
CAS:<p>TA-02 is a p38 MAPK inhibitor with IC50 of 20 nM.TA-02 especially inhibits TGFBR-2.</p>Fórmula:C20H13F2N3Pureza:99.35% - 99.79%Forma y color:SolidPeso molecular:333.33TA-01
CAS:<p>TA-01 is a potent CK1 and p38 MAPK inhibitor, with IC50s of 6.4 nM, 6.8 nM, 6.7 nM for CK1ε, CK1δ and p38 MAPK, respectively.</p>Fórmula:C20H12F3N3Pureza:99.55% - 99.94%Forma y color:SolidPeso molecular:351.32Ralimetinib dimesylate
CAS:<p>Ralimetinib dimesylate (LY2228820 dimesylate) is a orally available, p38 MAPK inhibitor with potential anti-inflammatory and antineoplastic activities.</p>Fórmula:C24H29FN6·2CH4O3SPureza:98% - 99.38%Forma y color:SolidPeso molecular:612.74Skepinone-L
CAS:<p>Skepinone-L (CBS3830) is a selective p38 mitogen-activated protein kinase inhibitor.</p>Fórmula:C24H21F2NO4Pureza:99.56% - >99.99%Forma y color:SolidPeso molecular:425.42SKF-86002
CAS:<p>SKF-86002 is an effective inhibitor of p38 MAP kinase (IC50: 0.5-1 uM); inhibits LPS-induced IL-1 and TNF-α production in human monocytes (IC50: 1 μM).</p>Fórmula:C16H12FN3SPureza:98% - 99.85%Forma y color:SolidPeso molecular:297.35SB 242235
CAS:<p>SB 242235 is a potent and selective p38 MAP kinase inhibitor that may be an effective therapy for cytokine-mediated diseases.</p>Fórmula:C19H20FN5OPureza:99.13% - 99.68%Forma y color:SolidPeso molecular:353.39Rhoifolin
CAS:<p>Rhoifolin (Apigenin 7-O-neohesperidoside) is extracted from Turpinia arguya Seem dried leaves.</p>Fórmula:C27H30O14Pureza:98.11% - 98.58%Forma y color:SolidPeso molecular:578.52TAK-715
CAS:<p>TAK-715 is a p38 MAPK inhibitor for p38α.</p>Fórmula:C24H21N3OSPureza:99.83%Forma y color:SolidPeso molecular:399.51PD 169316
CAS:<p>PD 169316 is a potent, cell-permeable and selective p38 MAP kinase inhibitor.</p>Fórmula:C20H13FN4O2Pureza:98.65%Forma y color:SolidPeso molecular:360.34AMG-47a
CAS:<p>AMG-47a inhibits Lck, T cell growth, and degrades KRAS oncoprotein, affecting EGFP-KRASG12V but not EGFP.</p>Fórmula:C29H28F3N5O2Pureza:98%Forma y color:SolidPeso molecular:535.56Acumapimod
CAS:<p>Acumapimod (BCT-197) is an orally active inhibitor of p38α MAPK (IC50 <1 μM).</p>Fórmula:C22H19N5O2Pureza:≥95%Forma y color:SolidPeso molecular:385.42Skatole
CAS:<p>Skatole (3-Methyl-1H-indole), produced by bacteria, regulates intestinal epithelial cellular functions through activating aryl hydrocarbon receptors and p38.</p>Fórmula:C9H9NPureza:99.74%Forma y color:Leaves From Petroleum Ether; White-Brown Scales SolidPeso molecular:131.17MW-150
CAS:<p>MW-150 (MW01-18-150SRM) is a unique protein kinase inhibitor, is a selective, CNS penetrant, and orally active inhibitor of p38α MAPK with a Ki of 101 nM.</p>Fórmula:C24H23N5Pureza:97.35% - 99.27%Forma y color:SolidPeso molecular:381.47Isoliquiritin apioside
CAS:<p>Isoliquiritin apioside, from Glycyrrhizae radix, inhibits MMP9, MAPK, NF-κB, reduces cancer cell invasion, angiogenesis, and fights oxidative DNA damage.</p>Fórmula:C26H30O13Pureza:98.84% - 99.27%Forma y color:SolidPeso molecular:550.51Esculin
CAS:<p>Esculin (Aesculin) is a glucoside found in horse chestnuts.</p>Fórmula:C15H16O9Pureza:97.93% - 99.83%Forma y color:Cream PowderPeso molecular:340.28Doramapimod
CAS:<p>Doramapimod (BIRB 796) is a highly potent inhibitor of p38 MAPK (Kd: 0.1 nM), but weakly inhibits c-RAF, Fyn, Lck, ERK-1, SYK, IKK2, and ZAP-70.</p>Fórmula:C31H37N5O3Pureza:97.14% - 98.80%Forma y color:SolidPeso molecular:527.66Bakuchiol
CAS:<p>Bakuchiol: anti-tumor, anti-helminthic, DNA polymerase1 inhibitor, cytotoxic, and anti-bacterial, may prevent dental caries.</p>Fórmula:C18H24OPureza:98.04% - 99.05%Forma y color:Brownish Yellow Liquid ViscousPeso molecular:256.38PH-797804
CAS:<p>PH-797804 is a pyridinone inhibitor of p38α (IC50: 26 nM, in a cell-free assay); 4-fold more selective versus p38β and does not inhibit JNK2.</p>Fórmula:C22H19BrF2N2O3Pureza:97.90% - 98.27%Forma y color:SolidPeso molecular:477.3Dehydrocorydaline
CAS:<p>1.</p>Fórmula:C22H24NO4Pureza:99.84%Forma y color:SolidPeso molecular:366.43Bisabolangelone
CAS:<p>Bisabolangelone: anti-tumor, anti-inflammatory, anti-microbial, antioxidant, blocks MAPK/NF-κB in dendritic cells.</p>Fórmula:C15H20O3Pureza:98.91%Forma y color:SolidPeso molecular:248.32SM-7368
CAS:<p>The NF-κB Activation Inhibitor III, controls the biological activity of NF-κB. It is primarily used for Inflammation/Immunology applications.</p>Fórmula:C10H5ClN4O5SPureza:99.64%Forma y color:SolidPeso molecular:328.69AMG 900
CAS:<p>AMG 900 is a potent and highly selective pan-Aurora kinases inhibitor for Aurora A/B/C with IC50 of 5 nM/4 nM /1 nM.</p>Fórmula:C28H21N7OSPureza:98.4% - 99.51%Forma y color:SolidPeso molecular:503.58SD-169
CAS:<p>SD-169 (SD 169) is a selective and ATP competitive the MAP kinases p38α and p38β inhibitor.</p>Fórmula:C9H8N2OPureza:98.6%Forma y color:SolidPeso molecular:160.17Afatinib
CAS:<p>Afatinib (BIBW 2992) is an irreversible and orally EGFR family inhibitor that inhibits EGFR and HER2. Afatinib has antitumor activity. Cost effective and quality assured.</p>Fórmula:C24H25ClFN5O3Pureza:98.56% - 99.9%Forma y color:Off-White SolidPeso molecular:485.94N-Feruloyloctopamine
CAS:<p>N-Feruloyloctopamine is a natural product.</p>Fórmula:C18H19NO5Pureza:99.70%Forma y color:SolidPeso molecular:329.35Sesamolin
CAS:<p>Sesamolin and sesamin guard nerves, reduce microglia damage by blocking p38 MAPK and caspase-3, and curb nitric oxide in stimulated cells.</p>Fórmula:C20H18O7Pureza:98.77% - 99.04%Forma y color:SolidPeso molecular:370.35Pamapimod
CAS:<p>Pamapimod (R1503) (R-1503, Ro4402257) is a novel, selective inhibitor of p38 mitogen-activated protein kinase.</p>Fórmula:C19H20F2N4O4Pureza:99.52% - 99.99%Forma y color:SolidPeso molecular:406.38Losmapimod
CAS:<p>Losmapimod (GSK-AHAB) (GW856553X; SB856553; GSK-AHAB) is a specific, potent, and orally active p38 MAPK inhibitor (pKi: 8.1/7.6 for p38α/β).</p>Fórmula:C22H26FN3O2Pureza:98.35% - 99.89%Forma y color:SolidPeso molecular:383.46RWJ-67657
CAS:<p>RWJ-67657 is a selective oral p38α/β MAPK inhibitor with IC50s of 1/11μM; inactive on p38γ/δ with cardioprotection.</p>Fórmula:C27H24FN3OPureza:99.66%Forma y color:SolidPeso molecular:425.5Sertaconazole
CAS:<p>Sertaconazole is a broad-spectrum antifungal.</p>Fórmula:C20H15Cl3N2OSPureza:99.483%Forma y color:SolidPeso molecular:437.77Paris saponin VII
CAS:<p>Paris saponin VII (Dioscini) shows inhibitory effects on cell proliferation.</p>Fórmula:C51H82O21Pureza:99.51% - 99.63%Forma y color:SolidPeso molecular:1031.18Talmapimod
CAS:<p>Talmapimod (SCIO-469): Oral ATP-competitive p38α inhibitor, IC50 = 9 nM (p38α), 90 nM (p38β), >2000-fold selectivity over 20 kinases.</p>Fórmula:C27H30ClFN4O3Pureza:98% - 99.9%Forma y color:SolidPeso molecular:513BMS582949
CAS:<p>BMS-582949 inhibits p38 MAPK with 13 nM IC50, blocking kinase activity and activation.</p>Fórmula:C22H26N6O2Pureza:98.11%Forma y color:SolidPeso molecular:406.48Pexmetinib
CAS:<p>Pexmetinib (ARRY-614) is an orally bioavailable dual p38 MAPK/Tie-2 inhibitor.Cost-effective and quality-assured.</p>Fórmula:C31H33FN6O3Pureza:99.07% - 99.66%Forma y color:SolidPeso molecular:556.63Dehydrocorydaline nitrate
CAS:<p>DHC curbs antibody and cell-mediated allergies, inhibits mitochondrial potential in macrophages, and has antinociceptive, anti-inflammatory effects.</p>Fórmula:C22H24N2O7Pureza:99.79% - 99.92%Forma y color:SolidPeso molecular:428.44VX-702
CAS:<p>VX-702: selective p38α MAPK inhibitor, potent anti-cytokine for rheumatoid arthritis.</p>Fórmula:C19H12F4N4O2Pureza:99% - >99.99%Forma y color:SolidPeso molecular:404.32TLC1566-0618
CAS:<p>TLC1566-0618 shows antitumor activity and targets stat.</p>Fórmula:C20H15NO3S3Pureza:98%Forma y color:SolidPeso molecular:413.53LY 294002 Hydrochloride
CAS:Producto controlado<p>Applications LY 294002 Hydrochloride is a highly selective inhibitor of Phosphatidylinositol 3-kinase (PI3K). It is a salt analogue of LY 294002 (L486590).<br>References Lin, C., et. al.: J. Biol. Chem., 286, 10483 (2011); Cao, H., et. al.: J. Biol. Chem., 288, 30399 (2013);<br></p>Fórmula:C19H17NO3·(HCl)Forma y color:NeatPeso molecular:343.8SB 706504
CAS:<p>SB 706504 is an effective p38 MAPK inhibitor that suppresses inflammatory gene expression in macrophages and inhibits TNFα production in COPD.</p>Fórmula:C24H19F3N8OPureza:98.686%Forma y color:SolidPeso molecular:492.46AL 8697
CAS:<p>AL 8697 is a selective p38α MAPK inhibitor (IC50 = 6 nM) with 14-fold selectivity over p38β (IC50 = 82 nM) and 300-fold selectivity over a panel of 91 kinases.</p>Fórmula:C21H21F3N4OPureza:99.55% - 99.89%Forma y color:SolidPeso molecular:402.41PF-05381941
CAS:<p>PF-05381941 is a selective and potent dual inhibitor of TAK1 and p38α that inhibits the kinase activity of TAK1 by binding to its active site.</p>Fórmula:C27H26N6O2Pureza:98.04%Forma y color:SolidPeso molecular:466.53EO-1606
CAS:<p>EO-1606 is a p38MAP kinase inhibitor with anti-inflammatory activity and may be used in studies of Alzheimer;s disease and dermatitis.</p>Fórmula:C21H17ClFNOPureza:98.28% - 98.84%Forma y color:SolidPeso molecular:353.82p38α inhibitor 4
CAS:<p>p38α inhibitor 4 is a selective MAPK p38α inhibitor, which is used to study diabetes, pain and chronic inflammation.</p>Fórmula:C14H7F6N3OPureza:99.69%Forma y color:SolidPeso molecular:347.215UR13870
CAS:<p>UR-13870 (Org 48762-0) is a p38 MAPK inhibitor that prevents bone damage in collagen-induced arthritis in mice.</p>Fórmula:C24H16F2N4Pureza:99.18% - >99.99%Forma y color:SolidPeso molecular:398.41AKP-001
CAS:<p>AKP-001 is a selective inhibitor of MAPK of the p38α isoform and is used in the study of immune and digestive disorders.</p>Fórmula:C21H13ClF2N4O2Pureza:99.50% - 99.92%Forma y color:SolidPeso molecular:426.8p38 MAPK Inhibitor
CAS:<p>p38 MAPK inhibitor is a potent inhibitor of p38 MAP kinase (IC50 = 35 nM). It inhibits senescence induced by the oncogene RAS.</p>Fórmula:C20H13ClFN3OPureza:99.91%Forma y color:SolidPeso molecular:365.79SB-747651A Dihydrochloride
CAS:<p>SB-747651A dihydrochloride, an MSK1 inhibitor (IC50=11 nM), also targets PRK2, RSK1, p70S6K, ROCK-II; potential in inflammation study.</p>Fórmula:C16H24Cl2N8OPureza:98.05%Forma y color:SolidPeso molecular:415.32Org OD 02-0
CAS:<p>10-Ethenyl-19-norprogesterone (Org OD 02-0) is a selective agonist for the membrane progesterone receptor α (mPRα) with an IC50 of 33.9 nM, known to activate</p>Fórmula:C22H30O2Pureza:98%Forma y color:SolidPeso molecular:326.47p38-α MAPK-IN-1
CAS:<p>p38-α MAPK-IN-1 is a MAPK14 (p38-α) inhibitor with IC50 of 2300 nM and 5500 nM in EFC displacement assay and HTRF assay,respectively.</p>Fórmula:C27H35N5O3Pureza:99.93%Forma y color:SolidPeso molecular:477.6PLK1/p38γ-IN-1
CAS:<p>PLK1/p38γ-IN-1 (compound 14) serves as a dual inhibitor targeting both PLK1 and p38γ kinases, effectively suppressing the proliferation of human hepatocellular</p>Fórmula:C21H26ClN3O2Pureza:98%Forma y color:SolidPeso molecular:387.9
