p38 MAPK
Las p38 MAPK son un subgrupo de MAPK que responden a señales de estrés y están involucradas en la regulación de la inflamación, la diferenciación celular, la apoptosis y la autofagia. La señalización de p38 MAPK es crucial en las respuestas inmunitarias y está implicada en varias enfermedades, incluidas las condiciones inflamatorias crónicas, el cáncer y los trastornos neurodegenerativos. En CymitQuimica, ofrecemos una gama completa de inhibidores y moduladores de p38 MAPK para apoyar su investigación en inflamación, respuesta al estrés y desarrollo terapéutico.
Se han encontrado 117 productos de "p38 MAPK"
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Rotundic acid
CAS:<p>Rotundic acid fights various cancers: HepG2, A375, NCI-H446, MCF-7, and HT-29.</p>Fórmula:C30H48O5Pureza:96.91% - 99.97%Forma y color:SolidPeso molecular:488.7Cornuside
CAS:<p>Cornuside boosts immunity, reduces inflammation, protects heart and liver, and guards against brain injury by modulating stress responses.</p>Fórmula:C24H30O14Pureza:99.86% - >99.99%Forma y color:SolidPeso molecular:542.49Andrograpanin
CAS:<p>Andrograpanin (19-HYDROXY-8(17),13-LABDADIEN-16,15-OLIDE) is a bioactive compound from Andrographis paniculata.</p>Fórmula:C20H30O3Pureza:99.03% - 99.457%Forma y color:SolidPeso molecular:318.45FERULIC ACID METHYL ESTER
CAS:<p>FERULIC ACID METHYL ESTER (Methyl ferulate) is a hydroxycinnamic acid that is abundant in plants. FERULIC ACID METHYL ESTER has antioxidant activities.</p>Fórmula:C11H12O4Pureza:99.66% - 99.95%Forma y color:SolidPeso molecular:208.21BMS-582949 hydrochloride
CAS:<p>The BMS-582949 hydrochloride (BMS-582949 HCl) is a highly specific p38α MAPK inhibitor (IC50: 13 nM).</p>Fórmula:C22H27ClN6O2Pureza:97.57% - 98.75%Forma y color:SolidPeso molecular:442.95R1487
CAS:<p>R1487 is an orally bioavailable and highly selective p38α mitogen-activated protein kinase inhibitor.</p>Fórmula:C19H18F2N4O3Pureza:99.77%Forma y color:SolidPeso molecular:388.37SR-318
CAS:<p>SR-318 inhibits TNF-α (IC50=283 nM), selectively targets p38 MAPK: IC50 of 5nM (p38α), 32nM (p38β), 6.11μM (p38α/β).</p>Fórmula:C27H33N5O2Pureza:99.74%Forma y color:SolidPeso molecular:459.58Afatinib Dimaleate
CAS:<p>Afatinib Dimaleate (BIBW 2992MA2) is an orally bioavailable anilino-quinazoline derivative and inhibitor of the EGFR family, with antineoplastic activity.</p>Fórmula:C32H33ClFN5O11Pureza:98.11% - 99.87%Forma y color:SolidPeso molecular:718.08TA-02
CAS:<p>TA-02 is a p38 MAPK inhibitor with IC50 of 20 nM.TA-02 especially inhibits TGFBR-2.</p>Fórmula:C20H13F2N3Pureza:99.35% - 99.79%Forma y color:SolidPeso molecular:333.33TA-01
CAS:<p>TA-01 is a potent CK1 and p38 MAPK inhibitor, with IC50s of 6.4 nM, 6.8 nM, 6.7 nM for CK1ε, CK1δ and p38 MAPK, respectively.</p>Fórmula:C20H12F3N3Pureza:99.55% - 99.94%Forma y color:SolidPeso molecular:351.32Ralimetinib dimesylate
CAS:<p>Ralimetinib dimesylate (LY2228820 dimesylate) is a orally available, p38 MAPK inhibitor with potential anti-inflammatory and antineoplastic activities.</p>Fórmula:C24H29FN6·2CH4O3SPureza:98% - 99.38%Forma y color:SolidPeso molecular:612.74Skepinone-L
CAS:<p>Skepinone-L (CBS3830) is a selective p38 mitogen-activated protein kinase inhibitor.</p>Fórmula:C24H21F2NO4Pureza:99.56% - >99.99%Forma y color:SolidPeso molecular:425.42SKF-86002
CAS:<p>SKF-86002 is an effective inhibitor of p38 MAP kinase (IC50: 0.5-1 uM); inhibits LPS-induced IL-1 and TNF-α production in human monocytes (IC50: 1 μM).</p>Fórmula:C16H12FN3SPureza:98% - 99.85%Forma y color:SolidPeso molecular:297.35SB 242235
CAS:<p>SB 242235 is a potent and selective p38 MAP kinase inhibitor that may be an effective therapy for cytokine-mediated diseases.</p>Fórmula:C19H20FN5OPureza:99.13% - 99.68%Forma y color:SolidPeso molecular:353.39Rhoifolin
CAS:<p>Rhoifolin (Apigenin 7-O-neohesperidoside) is extracted from Turpinia arguya Seem dried leaves.</p>Fórmula:C27H30O14Pureza:98.11% - 98.58%Forma y color:SolidPeso molecular:578.52TAK-715
CAS:<p>TAK-715 is a p38 MAPK inhibitor for p38α.</p>Fórmula:C24H21N3OSPureza:99.83%Forma y color:SolidPeso molecular:399.51PD 169316
CAS:<p>PD 169316 is a potent, cell-permeable and selective p38 MAP kinase inhibitor.</p>Fórmula:C20H13FN4O2Pureza:98.65%Forma y color:SolidPeso molecular:360.34AMG-47a
CAS:<p>AMG-47a inhibits Lck, T cell growth, and degrades KRAS oncoprotein, affecting EGFP-KRASG12V but not EGFP.</p>Fórmula:C29H28F3N5O2Pureza:98%Forma y color:SolidPeso molecular:535.56Acumapimod
CAS:<p>Acumapimod (BCT-197) is an orally active inhibitor of p38α MAPK (IC50 <1 μM).</p>Fórmula:C22H19N5O2Pureza:≥95%Forma y color:SolidPeso molecular:385.42Skatole
CAS:<p>Skatole (3-Methyl-1H-indole), produced by bacteria, regulates intestinal epithelial cellular functions through activating aryl hydrocarbon receptors and p38.</p>Fórmula:C9H9NPureza:99.74%Forma y color:Leaves From Petroleum Ether; White-Brown Scales SolidPeso molecular:131.17
