p38 MAPK
Las p38 MAPK son un subgrupo de MAPK que responden a señales de estrés y están involucradas en la regulación de la inflamación, la diferenciación celular, la apoptosis y la autofagia. La señalización de p38 MAPK es crucial en las respuestas inmunitarias y está implicada en varias enfermedades, incluidas las condiciones inflamatorias crónicas, el cáncer y los trastornos neurodegenerativos. En CymitQuimica, ofrecemos una gama completa de inhibidores y moduladores de p38 MAPK para apoyar su investigación en inflamación, respuesta al estrés y desarrollo terapéutico.
Se han encontrado 112 productos de "p38 MAPK"
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Cornuside
CAS:Cornuside boosts immunity, reduces inflammation, protects heart and liver, and guards against brain injury by modulating stress responses.Fórmula:C24H30O14Pureza:99.86% - >99.99%Forma y color:SolidPeso molecular:542.49Ref: TM-T4S2326
1mg96,00€5mg264,00€10mg415,00€25mg677,00€50mg935,00€100mg1.254,00€500mg2.527,00€1mL*10mM (DMSO)315,00€Sertaconazole
CAS:Sertaconazole is a broad-spectrum antifungal.Fórmula:C20H15Cl3N2OSPureza:99.483%Forma y color:SolidPeso molecular:437.77Ref: TM-T50005
5mg55,00€10mg78,00€25mg119,00€50mg172,00€100mg259,00€200mg388,00€1mL*10mM (DMSO)79,00€BMS-582949 hydrochloride
CAS:The BMS-582949 hydrochloride (BMS-582949 HCl) is a highly specific p38α MAPK inhibitor (IC50: 13 nM).Fórmula:C22H27ClN6O2Pureza:97.57% - 98.75%Forma y color:SolidPeso molecular:442.95Ref: TM-T3462
1mg34,00€5mg67,00€10mg96,00€25mg161,00€50mg250,00€100mg371,00€200mg523,00€1mL*10mM (DMSO)73,00€R1487
CAS:R1487 is an orally bioavailable and highly selective p38α mitogen-activated protein kinase inhibitor.Fórmula:C19H18F2N4O3Pureza:99.77%Forma y color:SolidPeso molecular:388.37SR-318
CAS:SR-318 inhibits TNF-α (IC50=283 nM), selectively targets p38 MAPK: IC50 of 5nM (p38α), 32nM (p38β), 6.11μM (p38α/β).Fórmula:C27H33N5O2Pureza:99.74%Forma y color:SolidPeso molecular:459.58Ref: TM-T12997
2mg35,00€5mg55,00€10mg92,00€25mg166,00€50mg259,00€100mg371,00€200mg533,00€1mL*10mM (DMSO)55,00€Afatinib Dimaleate
CAS:Afatinib Dimaleate (BIBW 2992MA2) is an orally bioavailable anilino-quinazoline derivative and inhibitor of the EGFR family, with antineoplastic activity.Fórmula:C32H33ClFN5O11Pureza:98.11% - 99.87%Forma y color:SolidPeso molecular:718.08TA-02
CAS:TA-02 is a p38 MAPK inhibitor with IC50 of 20 nM.TA-02 especially inhibits TGFBR-2.Fórmula:C20H13F2N3Pureza:99.35% - 99.79%Forma y color:SolidPeso molecular:333.33Ref: TM-T4646
5mg37,00€10mg55,00€25mg99,00€50mg152,00€100mg230,00€500mgA consultar1mL*10mM (DMSO)40,00€TA-01
CAS:TA-01 is a potent CK1 and p38 MAPK inhibitor, with IC50s of 6.4 nM, 6.8 nM, 6.7 nM for CK1ε, CK1δ and p38 MAPK, respectively.Fórmula:C20H12F3N3Pureza:99.55% - 99.94%Forma y color:SolidPeso molecular:351.32Ref: TM-T4645
2mg34,00€5mg50,00€10mg80,00€25mg147,00€50mg224,00€100mg313,00€200mg439,00€1mL*10mM (DMSO)67,00€Ralimetinib dimesylate
CAS:Ralimetinib dimesylate (LY2228820 dimesylate) is a orally available, p38 MAPK inhibitor with potential anti-inflammatory and antineoplastic activities.Fórmula:C24H29FN6·2CH4O3SPureza:98% - 99.38%Forma y color:SolidPeso molecular:612.74Skepinone-L
CAS:Skepinone-L (CBS3830) is a selective p38 mitogen-activated protein kinase inhibitor.Fórmula:C24H21F2NO4Pureza:99.56% - >99.99%Forma y color:SolidPeso molecular:425.42Ref: TM-T6130
1mg38,00€2mg49,00€5mg79,00€10mg119,00€25mg208,00€50mg313,00€100mg465,00€1mL*10mM (DMSO)87,00€SKF-86002
CAS:SKF-86002 is an effective inhibitor of p38 MAP kinase (IC50: 0.5-1 uM); inhibits LPS-induced IL-1 and TNF-α production in human monocytes (IC50: 1 μM).Fórmula:C16H12FN3SPureza:98% - 99.85%Forma y color:SolidPeso molecular:297.35SB 242235
CAS:SB 242235 is a potent and selective p38 MAP kinase inhibitor that may be an effective therapy for cytokine-mediated diseases.Fórmula:C19H20FN5OPureza:99.13% - 99.68%Forma y color:SolidPeso molecular:353.39Rhoifolin
CAS:Rhoifolin (Apigenin 7-O-neohesperidoside) is extracted from Turpinia arguya Seem dried leaves.Fórmula:C27H30O14Pureza:98.11% - 98.58%Forma y color:SolidPeso molecular:578.52TAK-715
CAS:TAK-715 is a p38 MAPK inhibitor for p38α.Fórmula:C24H21N3OSPureza:99.83%Forma y color:SolidPeso molecular:399.51Ref: TM-T6150
1mg38,00€2mg50,00€5mg82,00€10mg94,00€25mg166,00€50mg306,00€100mg480,00€1mL*10mM (DMSO)92,00€PD 169316
CAS:PD 169316 is a potent, cell-permeable and selective p38 MAP kinase inhibitor.Fórmula:C20H13FN4O2Pureza:98.65%Forma y color:SolidPeso molecular:360.34AMG-47a
CAS:AMG-47a inhibits Lck, T cell growth, and degrades KRAS oncoprotein, affecting EGFP-KRASG12V but not EGFP.Fórmula:C29H28F3N5O2Pureza:98%Forma y color:SolidPeso molecular:535.56Acumapimod
CAS:Acumapimod (BCT-197) is an orally active inhibitor of p38α MAPK (IC50 <1 μM).Fórmula:C22H19N5O2Pureza:≥95%Forma y color:SolidPeso molecular:385.42Skatole
CAS:Skatole (3-Methyl-1H-indole), produced by bacteria, regulates intestinal epithelial cellular functions through activating aryl hydrocarbon receptors and p38.Fórmula:C9H9NPureza:99.74%Forma y color:Leaves From Petroleum Ether; White-Brown Scales SolidPeso molecular:131.17MW-150
CAS:MW-150 (MW01-18-150SRM) is a unique protein kinase inhibitor, is a selective, CNS penetrant, and orally active inhibitor of p38α MAPK with a Ki of 101 nM.Fórmula:C24H23N5Pureza:97.35% - 99.27%Forma y color:SolidPeso molecular:381.47Ref: TM-T5494
1mg37,00€5mg90,00€10mg144,00€25mg289,00€50mg430,00€100mg620,00€500mg1.333,00€1mL*10mM (DMSO)108,00€Kaempferol-3-O-glucorhamnoside
CAS:Kaempferol-3-O-glucorhamnoside (Kaempferol 3-glucorhamnoside), a flavonoid derived from plant Thesium chinense Turcz, inhibits inflammatory responses via MAPKFórmula:C27H30O15Pureza:96.96% - 98.17%Forma y color:SolidPeso molecular:594.5Ref: TM-T5S0089
1mg48,00€5mg92,00€10mg136,00€25mg215,00€50mg323,00€100mg469,00€200mg647,00€1mL*10mM (DMSO)122,00€
