p38 MAPK
Las p38 MAPK son un subgrupo de MAPK que responden a señales de estrés y están involucradas en la regulación de la inflamación, la diferenciación celular, la apoptosis y la autofagia. La señalización de p38 MAPK es crucial en las respuestas inmunitarias y está implicada en varias enfermedades, incluidas las condiciones inflamatorias crónicas, el cáncer y los trastornos neurodegenerativos. En CymitQuimica, ofrecemos una gama completa de inhibidores y moduladores de p38 MAPK para apoyar su investigación en inflamación, respuesta al estrés y desarrollo terapéutico.
Se han encontrado 112 productos de "p38 MAPK"
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Esculin
CAS:Esculin (Aesculin) is a glucoside found in horse chestnuts.Fórmula:C15H16O9Pureza:97.93% - 99.83%Forma y color:Cream PowderPeso molecular:340.28Doramapimod
CAS:Doramapimod (BIRB 796) is a highly potent inhibitor of p38 MAPK (Kd: 0.1 nM), but weakly inhibits c-RAF, Fyn, Lck, ERK-1, SYK, IKK2, and ZAP-70.Fórmula:C31H37N5O3Pureza:97.14% - 98.80%Forma y color:SolidPeso molecular:527.66Ref: TM-T6277
1g532,00€5mg34,00€10mg52,00€25mg74,00€50mg96,00€100mg120,00€200mg213,00€500mg359,00€1mL*10mM (DMSO)42,00€Bakuchiol
CAS:Bakuchiol: anti-tumor, anti-helminthic, DNA polymerase1 inhibitor, cytotoxic, and anti-bacterial, may prevent dental caries.Fórmula:C18H24OPureza:98.04% - 99.05%Forma y color:Brownish Yellow Liquid ViscousPeso molecular:256.38PH-797804
CAS:PH-797804 is a pyridinone inhibitor of p38α (IC50: 26 nM, in a cell-free assay); 4-fold more selective versus p38β and does not inhibit JNK2.Fórmula:C22H19BrF2N2O3Pureza:97.90% - 98.27%Forma y color:SolidPeso molecular:477.3Ref: TM-T1974
1mg43,00€5mg88,00€10mg137,00€25mg241,00€50mg385,00€100mg595,00€500mg1.251,00€1mL*10mM (DMSO)92,00€Ref: TM-T5S2358
1mg49,00€2mg69,00€5mg105,00€10mg137,00€25mg197,00€50mg295,00€100mg447,00€1mL*10mM (DMSO)116,00€Bisabolangelone
CAS:Bisabolangelone: anti-tumor, anti-inflammatory, anti-microbial, antioxidant, blocks MAPK/NF-κB in dendritic cells.Fórmula:C15H20O3Pureza:98.91%Forma y color:SolidPeso molecular:248.32SM-7368
CAS:The NF-κB Activation Inhibitor III, controls the biological activity of NF-κB. It is primarily used for Inflammation/Immunology applications.Fórmula:C10H5ClN4O5SPureza:99.64%Forma y color:SolidPeso molecular:328.69Ref: TM-T22115
5mg44,00€10mg71,00€25mg128,00€50mg178,00€100mg268,00€200mg389,00€1mL*10mM (DMSO)52,00€SD-169
CAS:SD-169 (SD 169) is a selective and ATP competitive the MAP kinases p38α and p38β inhibitor.Fórmula:C9H8N2OPureza:98.6%Forma y color:SolidPeso molecular:160.17Afatinib
CAS:Afatinib (BIBW 2992) is an irreversible and orally EGFR family inhibitor that inhibits EGFR and HER2. Afatinib has antitumor activity. Cost effective and quality assured.Fórmula:C24H25ClFN5O3Pureza:98.56% - 99.9%Forma y color:Off-White SolidPeso molecular:485.94Ref: TM-T21312
5mg34,00€10mg49,00€25mg81,00€50mg109,00€100mg137,00€200mg168,00€500mg284,00€1mL*10mM (DMSO)50,00€N-Feruloyloctopamine
CAS:N-Feruloyloctopamine is a natural product.Fórmula:C18H19NO5Pureza:99.70%Forma y color:SolidPeso molecular:329.35Ref: TM-TN1968
1mg85,00€5mg195,00€10mg288,00€25mg485,00€50mg695,00€100mg949,00€1mL*10mM (DMSO)168,00€Sesamolin
CAS:Sesamolin and sesamin guard nerves, reduce microglia damage by blocking p38 MAPK and caspase-3, and curb nitric oxide in stimulated cells.Fórmula:C20H18O7Pureza:98.77% - 99.04%Forma y color:SolidPeso molecular:370.35Ref: TM-T5S2283
1mg35,00€2mg50,00€5mg75,00€10mg120,00€25mg197,00€50mg294,00€100mg437,00€200mg622,00€1mL*10mM (DMSO)84,00€Pamapimod
CAS:Pamapimod (R1503) (R-1503, Ro4402257) is a novel, selective inhibitor of p38 mitogen-activated protein kinase.Fórmula:C19H20F2N4O4Pureza:99.52% - 99.99%Forma y color:SolidPeso molecular:406.38Losmapimod
CAS:Losmapimod (GSK-AHAB) (GW856553X; SB856553; GSK-AHAB) is a specific, potent, and orally active p38 MAPK inhibitor (pKi: 8.1/7.6 for p38α/β).Fórmula:C22H26FN3O2Pureza:98.35% - 99.89%Forma y color:SolidPeso molecular:383.46Ref: TM-T2277
2mg34,00€5mg50,00€10mg73,00€25mg132,00€50mg213,00€100mg385,00€500mg873,00€1mL*10mM (DMSO)52,00€RWJ-67657
CAS:RWJ-67657 is a selective oral p38α/β MAPK inhibitor with IC50s of 1/11μM; inactive on p38γ/δ with cardioprotection.Fórmula:C27H24FN3OPureza:99.66%Forma y color:SolidPeso molecular:425.5Ref: TM-T16812
2mg44,00€5mg66,00€10mg90,00€25mg205,00€50mg331,00€100mg533,00€500mg1.125,00€1mL*10mM (DMSO)73,00€Paris saponin VII
CAS:Paris saponin VII (Dioscini) shows inhibitory effects on cell proliferation.Fórmula:C51H82O21Pureza:99.51% - 99.63%Forma y color:SolidPeso molecular:1031.18Talmapimod
CAS:Talmapimod (SCIO-469): Oral ATP-competitive p38α inhibitor, IC50 = 9 nM (p38α), 90 nM (p38β), >2000-fold selectivity over 20 kinases.Fórmula:C27H30ClFN4O3Pureza:98% - 99.9%Forma y color:SolidPeso molecular:513Ref: TM-T12871
1mg50,00€2mg73,00€5mg109,00€10mg168,00€25mg358,00€50mg530,00€100mg758,00€1mL*10mM (DMSO)124,00€BMS582949
CAS:BMS-582949 inhibits p38 MAPK with 13 nM IC50, blocking kinase activity and activation.Fórmula:C22H26N6O2Pureza:98.11%Forma y color:SolidPeso molecular:406.48Ref: TM-T6789
1mg82,00€2mg114,00€5mg200,00€10mg284,00€25mg477,00€50mg692,00€100mg973,00€1mL*10mM (DMSO)200,00€Pexmetinib
CAS:Pexmetinib (ARRY-614) is an orally bioavailable dual p38 MAPK/Tie-2 inhibitor.Cost-effective and quality-assured.Fórmula:C31H33FN6O3Pureza:99.07% - 99.66%Forma y color:SolidPeso molecular:556.63Andrograpanin
CAS:Andrograpanin (19-HYDROXY-8(17),13-LABDADIEN-16,15-OLIDE) is a bioactive compound from Andrographis paniculata.Fórmula:C20H30O3Pureza:99.03% - 99.457%Forma y color:SolidPeso molecular:318.45FERULIC ACID METHYL ESTER
CAS:FERULIC ACID METHYL ESTER (Methyl ferulate) is a hydroxycinnamic acid that is abundant in plants. FERULIC ACID METHYL ESTER has antioxidant activities.Fórmula:C11H12O4Pureza:99.66% - 99.95%Forma y color:SolidPeso molecular:208.21
