Transportador de membrana / canal de iones
Los inhibidores de transportadores de membrana y canales iónicos son compuestos que bloquean la función de proteínas responsables del transporte de iones, nutrientes y otras moléculas a través de las membranas celulares. Estos inhibidores son cruciales para estudiar la regulación de la homeostasis celular, la transducción de señales y la neurotransmisión. Los inhibidores de transportadores de membrana y canales iónicos también son importantes para desarrollar tratamientos para trastornos como la epilepsia, las enfermedades cardiovasculares y los síndromes metabólicos. En CymitQuimica, ofrecemos una amplia selección de inhibidores de alta calidad de transportadores de membrana y canales iónicos para apoyar su investigación en fisiología, neurociencia y farmacología.
Subcategorías de "Transportador de membrana / canal de iones"
- ABC(3 productos)
- ATPasa(93 productos)
- Receptor de adiponectina(5 productos)
- CFTR(64 productos)
- Receptor CGRP(51 productos)
- Canal de calcio(493 productos)
- Canal de cloruro(49 productos)
- Receptor GABA(336 productos)
- Transportador de monoamina(23 productos)
- Transportador de monocarboxilato(17 productos)
- NKCC(2 productos)
- NPC1L1(3 productos)
- Cotransportador de Na-K-Cl(8 productos)
- OAT(27 productos)
- OCT(7 productos)
- P-gp(53 productos)
- Canal de potasio(276 productos)
- Bomba de protones(39 productos)
- SGLT(30 productos)
- Canal de sodio(202 productos)
- Canal TRP / TRPV(92 productos)
Mostrar 13 subcategorías más
Se han encontrado 2270 productos de "Transportador de membrana / canal de iones"
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
P2X4 antagonist-4
<p>P2X4 antagonist-4 (compound 64) is a potent P2X4R antagonist with an IC50 value of 8 µM. It can inhibit ATP-induced activation of the NLRP3 inflammasome and the subsequent release of IL-1β.</p>Fórmula:C27H22FN3O4SForma y color:SolidPeso molecular:503.545Hyp9
CAS:<p>Hyp9, a specific agonist for the transient receptor potential canonical 6 (TRPC6) channel, is utilized in spinal cord injury (SCI) research [1].</p>Fórmula:C18H26O5Forma y color:SolidPeso molecular:322.40Chlorotoxin TFA
<p>Chlorotoxin TFA, a scorpion venom peptide, blocks chloride channels and has anti-cancer properties.</p>Fórmula:C160H250F3N53O49S11Forma y color:SolidPeso molecular:4109.74JAMI1001A
CAS:<p>JAMI1001A enhances AMPA receptor signaling, slows deactivation/desensitization for flip/flop isoforms.</p>Fórmula:C16H17F3N4O3SForma y color:SolidPeso molecular:402.39SLC26A3-IN-2
CAS:<p>Vilobelimab (CaCP-29) is a human-mouse chimeric IgG antibody targeting human complement component 5a, a C5a inhibitor that inhibits neutrophil activation.</p>Fórmula:C19H13ClN2O2SPureza:99.86%Forma y color:SolidPeso molecular:368.84Homocarnosine
CAS:<p>Homocarnosine is an endogenous dipeptide in cerebral regions and cerebrospinal fluid.</p>Fórmula:C10H16N4O3Forma y color:SolidPeso molecular:240.26Anticonvulsant agent 9
<p>Anticonvulsant agent 9 (compound 4f) is an activator of the α1β2γ2GABA_A receptor, with an EC50 value of 1.24 μM. It inhibits the inactivation of Nav1.2 channels and exhibits significant anticonvulsant activity.</p>Fórmula:C22H24N4O2Forma y color:SolidPeso molecular:376.45Bendroflumethiazide
CAS:<p>Bendroflumethiazide (Naturetin) is a thiazide diuretic with actions and uses similar to those of HYDROCHLOROTHIAZIDE. It has been used in the treatment of familial hyperkalemia, hypertension, edema, and urinary tract disorders. (From Martindale, The Extra Pharmacopoeia, 30th ed, p810)</p>Fórmula:C15H14F3N3O4S2Pureza:98% - >99.99%Forma y color:Crystals From Dioxane SolidPeso molecular:421.41TP-050
CAS:<p>TP-050: potent, selective NMDAR agonist, EC50 0.51 µM (GluN2A), 9.6 µM (GluN2D), BBB permeable, boosts hippocampal LTP.</p>Fórmula:C16H15ClF2N6OForma y color:SolidPeso molecular:380.78Trans (2,3)-Dihydrotetrabenazine
CAS:<p>Trans (2,3)-Dihydrotetrabenazine is a Tetrabenazine metabolite, shows inhibition activity on vesicular monoamine transporter (VMAT2).</p>Fórmula:C19H29NO3Pureza:98%Forma y color:SolidPeso molecular:319.44Levamlodipine besylate Hemipentahydrate
CAS:<p>Levamlodipine besylate hemipentahydrate is the besylate hemipentahydrate salt form of Levamlodipine. It is an orally effective calcium channel blocker with antioxidative and vasodilatory properties. This compound can reduce serum malondialdehyde (MDA) levels, enhance the activity of superoxide dismutase (SOD), and alleviate oxidative stress. Levamlodipine besylate hemipentahydrate is relevant for research in vascular dementia, hypertension, and cerebrovascular diseases.</p>Fórmula:C20H25ClN2O5·C6H6O3SH2OForma y color:SolidPeso molecular:1224.18Crofelemer
CAS:<p>Crofelemer (Provir) is an orally active antidiarrheal agent. It targets the cystic fibrosis transmembrane conductance regulator (CFTR) and calcium-activated chloride channels (CACC), which are responsible for chloride and fluid secretion in the gastrointestinal tract. Crofelemer is applicable for research in diarrhea-related conditions.</p>Forma y color:SolidIdactamab
CAS:<p>Idactamab (INT-001) is a monoclonal antibody to the human amino acid transport protein ASCT2.</p>Pureza:> 95%Forma y color:LiquidPeso molecular:146.2 kDaBeKm-1
CAS:<p>Potent, selective hERG (KV11.1) blocker; doesn't affect 14 other K+ channels; extends QTc in rabbit heart dose-dependently.</p>Fórmula:C174H261N51O52S6Pureza:98%Forma y color:SolidPeso molecular:4091.65Cevadine
<p>Cevadine is a natural product that can be used as a reference standard.</p>Fórmula:C32H49NO9Forma y color:SolidPeso molecular:591.742Sulcardine 2HCl
CAS:<p>Sulcardine 2HCl is a multi-ion channel blocker that blocks the properties of hERG and hNav1.5 channels and can be used to study atrial fibrillation.</p>Fórmula:C24H35Cl2N3O4SPureza:99.33% - 99.76%Forma y color:SoildPeso molecular:532.5231-(1-Methyl-1h-pyrazol-4-yl)-ethanone
CAS:<p>1-(1-Methyl-1h-pyrazol-4-yl)-ethanone is a high purity biochemical reagent that can be used in research related to life sciences.</p>Fórmula:C6H8N2OPureza:99.92%Forma y color:SolidPeso molecular:124.14EVT-401
<p>EVT-401 (P2X7 receptor antagonist-1), a purinergic P2X7 receptor antagonist, demonstrates efficacy in combating neuroinflammation [1].</p>Fórmula:C22H20F4N2O3Forma y color:SolidPeso molecular:436.4AChE/Aβ-IN-2
<p>AChE/Aβ-IN-2 (compound 33) is a powerful, orally active acetylcholinesterase (AChE) inhibitor with an IC50 of 135 nM.</p>Fórmula:C20H25ClN4Forma y color:SolidPeso molecular:356.89Ebio3
<p>Ebio3 is a selective potassium ion channel (KCNQ2) inhibitor with an IC50 of 1.2 nM. It binds to the KCNQ2 channel via its hydrophobic tail, causing the inward movement of the S6 helix, which results in the closure of the internal gate. The inhibitory effect of Ebio3 is equally effective on pathogenic KCNQ2 mutants, such as R75C and I238L, reducing their outward current by approximately 80%. Ebio3 holds potential for research in neurological disorders like epilepsy.</p>Fórmula:C19H23F2N3O2Forma y color:SolidPeso molecular:363.4
