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Transportador de membrana / canal de iones

Transportador de membrana / canal de iones

Los inhibidores de transportadores de membrana y canales iónicos son compuestos que bloquean la función de proteínas responsables del transporte de iones, nutrientes y otras moléculas a través de las membranas celulares. Estos inhibidores son cruciales para estudiar la regulación de la homeostasis celular, la transducción de señales y la neurotransmisión. Los inhibidores de transportadores de membrana y canales iónicos también son importantes para desarrollar tratamientos para trastornos como la epilepsia, las enfermedades cardiovasculares y los síndromes metabólicos. En CymitQuimica, ofrecemos una amplia selección de inhibidores de alta calidad de transportadores de membrana y canales iónicos para apoyar su investigación en fisiología, neurociencia y farmacología.

Subcategorías de "Transportador de membrana / canal de iones"

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Se han encontrado 2270 productos de "Transportador de membrana / canal de iones"

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  • NMDA agonist 1
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    NMDA agonist 1

    CAS:
    <p>NMDA agonist 1 (compound 42d) is a potent NMDA agonist with a Ki value of 96 nM. It acts as a partial agonist of the GluN1/GluN2B complex, exhibiting an EC50 value of 78 nM.</p>
    Fórmula:C12H13N3O3S
    Forma y color:Solid
    Peso molecular:279.315

    Ref: TM-T204880

  • Antidepressant agent 9
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    Antidepressant agent 9

    CAS:
    <p>Antidepressant agent 9 (Compound 24) is an orally active inhibitor of NMDAR and SERT, with IC50 values of 3.50 μM and 1044 nM, respectively. It exhibits good metabolic stability and plasma exposure, and demonstrates antidepressant-like effects in the forced swim test in mice.</p>
    Fórmula:C17H24N2
    Forma y color:Solid
    Peso molecular:256.386

    Ref: TM-T205640

  • SGC-CAMKK2-1
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    SGC-CAMKK2-1

    CAS:
    <p>SGC-CAMKK2-1 is a selective inhibitor of calcium/calmodulin-dependent protein kinase kinase 2 (CAMKK2) with an IC50 of 30 nM. It effectively inhibits AMPK phosphorylation in C4-2 cells, exhibiting an IC50 value of 1.6 µM.</p>
    Fórmula:C26H23NO3
    Forma y color:Solid
    Peso molecular:397.466

    Ref: TM-T205037

  • Antidepressant agent 8
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    Antidepressant agent 8

    CAS:
    <p>Antidepressant agent 8 (Compound 1f) acts as a selective antagonist for the NMDA receptor GluN1/2A (NMDA receptorGluN1/2A), with an IC50 of 2.94 μmol/L. In a hydrocortisone-induced zebrafish depression model, it demonstrates antidepressant-like effects and shows good blood-brain barrier penetration.</p>
    Fórmula:C18H23FN4OS2
    Forma y color:Solid
    Peso molecular:394.53

    Ref: TM-T205232

  • O4I4
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    O4I4

    CAS:
    <p>O4I4 is an OCT4-inducing compound capable of activating endogenous OCT4 and its associated signaling pathways, shown anti-aging effects.</p>
    Fórmula:C15H20N2S
    Pureza:99.74%
    Forma y color:Solid
    Peso molecular:260.4

    Ref: TM-T87051

  • LY503430
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    LY503430

    CAS:
    <p>LY503430: Oral AMPA enhancer with nootropic, neuroprotective properties, mitigates 6-OHDA/MPTP brain damage.</p>
    Fórmula:C20H25FN2O3S
    Pureza:98%
    Forma y color:Solid
    Peso molecular:392.49

    Ref: TM-T27959

  • Logo de CymitQuimica
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    Antimalarial agent 7

    <p>Antimalarial agent 7 is a potent and effective inhibitor of PfATP4. Antimalarial agent 7 has potential for the study of the human plasmodium falciparum.</p>
    Fórmula:C23H22F2N4O3
    Forma y color:Solid
    Peso molecular:440.44

    Ref: TM-T62537

  • Olisutrigine bromide
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    Olisutrigine bromide

    CAS:
    <p>Olisutrigine bromide is a sodium channel blocker used as an analgesic.</p>
    Fórmula:C25H35BrN2
    Forma y color:Solid
    Peso molecular:443.463

    Ref: TM-T205479

  • ErSO-TFPy
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    ErSO-TFPy

    CAS:
    <p>ErSO-TFPy activates the sodium ion channel TRPM4, resulting in an imbalance of intracellular calcium and sodium ions. It exhibits low nanomolar-level cytotoxicity (IC50 = 5-25 nM) by inducing necrosis in ERα+ breast cancer cell lines. Additionally, ErSO-TFPy shows antitumor activity in mouse models.</p>
    Fórmula:C19H13F7N2O2
    Forma y color:Solid
    Peso molecular:434.307

    Ref: TM-T205320

  • Moxetomidate
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    Moxetomidate

    CAS:
    <p>Moxetomidate is a GABAA receptor (GABAA receptor) agonist with hypnotic properties.</p>
    Fórmula:C15H18N2O3
    Forma y color:Solid
    Peso molecular:274.315

    Ref: TM-T205308

  • Crinecerfont tosylate
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    Crinecerfont tosylate

    CAS:
    <p>Crinecerfont tosylate is an effective oral CRF1 receptor antagonist. It is applicable to studies involving congenital adrenal hyperplasia (CAH).</p>
    Fórmula:C34H36ClFN2O4S2
    Forma y color:Solid
    Peso molecular:655.242

    Ref: TM-T205414

  • (3S,6R)-NML
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    (3S,6R)-NML

    CAS:
    <p>(3S,6R)-NML is an NMDA receptor antagonist with pIC50 values of 4.8 [GluN1-GluN2A], 4.6 [GluN1-GluN2B], 5.0 [GluN1-GluN2C], and 5.0 [GluN1-GluN2D]. It is applicable in the study of depression.</p>
    Fórmula:C20H27NO
    Forma y color:Solid
    Peso molecular:297.435

    Ref: TM-T205321

  • Logo de CymitQuimica
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    URAT1 inhibitor 2

    <p>URAT1 inhibitor 2: oral URAT1/CYP blocker, IC50 of 1.36μM (URAT1), 16.97μM (CYP1A2), 5.22μM (CYP2C9); potential gout treatment.</p>
    Fórmula:C21H18BrN3O2S
    Forma y color:Solid
    Peso molecular:456.36

    Ref: TM-T62825

  • Insecticidal agent 21
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    Insecticidal agent 21

    CAS:
    <p>Insecticidal agent 21 (Compound 6) is an insecticide targeting Culex pipiens larvae with an LC50 of 0.4 μg/mL. It achieves multi-target neurotoxicity by inhibiting acetylcholinesterase (AChE) and simultaneously targeting other neural receptors, including nicotinic acetylcholine receptors (nAChR), voltage-gated sodium channels (VGSC), and γ-aminobutyric acid receptors (GABAAR). Insecticidal agent 21 shows potent insecticidal activity and can be utilized in the development of new insecticides to combat mosquito resistance to conventional agents.</p>
    Fórmula:C37H40ClN3O2
    Forma y color:Solid
    Peso molecular:594.185

    Ref: TM-T206704

  • ATPase-IN-5
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    ATPase-IN-5

    CAS:
    <p>ATPase-IN-5 (Compound 11) is an antifungal Pma1p (H+ -ATPase) inhibitor (IC50 = 12.7 μM) that inhibits the growth of Candida albicans and Saccharomyces cerevisiae.</p>
    Fórmula:C10H10N4O3S
    Pureza:99.19%
    Forma y color:Solid
    Peso molecular:266.28

    Ref: TM-T204943

  • Logo de CymitQuimica
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    PDE1-IN-4

    <p>PDE1-IN-4: inhibits PDE1C/A/B with IC50s 10/145/354 nM, may help study idiopathic pulmonary fibrosis.</p>
    Fórmula:C33H33N3O4
    Forma y color:Solid
    Peso molecular:535.63

    Ref: TM-T63776

  • Logo de CymitQuimica
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    P2X receptor-1

    <p>P2X receptor-1 is a potential inhibitor of P2X receptor for the treatment of pain and inflammation.</p>
    Fórmula:C14H14ClN3O3S2
    Forma y color:Solid
    Peso molecular:371.86

    Ref: TM-T61490

  • 5-O-Desmethyl donepezil
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    5-O-Desmethyl donepezil

    CAS:
    <p>5-O-Desmethyl donepezil is a metabolite of Donepezil that acts as an inhibitor of hERG channels, with an IC50 of 1.5 μM.</p>
    Fórmula:C23H27NO3
    Forma y color:Solid
    Peso molecular:365.465

    Ref: TM-T206238

  • ICA-105665
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    ICA-105665

    CAS:
    <p>ICA-105665 is an orally active Kv7.2/7.3/7.5 channel opener, CNS-penetrant with antiseizure effects, and low hepatocyte cytotoxicity.</p>
    Fórmula:C19H15F2N3O2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:355.34

    Ref: TM-T11606

  • GNE-616
    Targetmol
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    GNE-616

    CAS:
    <p>GNE-616: a potent, stable, oral Nav1.7 inhibitor; Ki: 0.79 nM, Kd: 0.38 nM; for chronic pain.</p>
    Fórmula:C24H23F4N5O3S
    Pureza:98%
    Forma y color:Solid
    Peso molecular:537.53

    Ref: TM-T11439