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Transportador de membrana / canal de iones

Transportador de membrana / canal de iones

Los inhibidores de transportadores de membrana y canales iónicos son compuestos que bloquean la función de proteínas responsables del transporte de iones, nutrientes y otras moléculas a través de las membranas celulares. Estos inhibidores son cruciales para estudiar la regulación de la homeostasis celular, la transducción de señales y la neurotransmisión. Los inhibidores de transportadores de membrana y canales iónicos también son importantes para desarrollar tratamientos para trastornos como la epilepsia, las enfermedades cardiovasculares y los síndromes metabólicos. En CymitQuimica, ofrecemos una amplia selección de inhibidores de alta calidad de transportadores de membrana y canales iónicos para apoyar su investigación en fisiología, neurociencia y farmacología.

Subcategorías de "Transportador de membrana / canal de iones"

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Se han encontrado 2270 productos de "Transportador de membrana / canal de iones"

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  • (RS)-AMPA hydrobromide
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    (RS)-AMPA hydrobromide

    CAS:
    <p>AMPAR agonist</p>
    Fórmula:C7H11BrN2O4
    Pureza:98%
    Forma y color:Solid
    Peso molecular:267.08

    Ref: TM-T23267

  • KV1.3-IN-2
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    KV1.3-IN-2

    CAS:
    <p>KV1.3-IN-2 (Compound I) selectively inhibits the kv1.3 potassium channel without affecting the hERG channel. It is applicable in research related to immune-associated diseases such as psoriasis, rheumatoid arthritis, and systemic lupus erythematosus.</p>
    Fórmula:C16H23ClN2O4
    Forma y color:Solid
    Peso molecular:342.818

    Ref: TM-T205655

  • Opakalim
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    Opakalim

    CAS:
    <p>Opakalim is an activator of potassium channels (potassium channel) and exhibits anticonvulsant activity.</p>
    Fórmula:C18H22F2N4O
    Forma y color:Solid
    Peso molecular:348.39

    Ref: TM-T206117

  • Logo de CymitQuimica
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    WS-898

    <p>WS-898 boosts paclitaxel efficacy in resistant cells by inhibiting ABCB1; IC50: SW620/Ad300 - 5.0 nM, KB-C2 - 3.67 nM, HEK293/ABCB1 - 3.68 nM.</p>
    Fórmula:C33H25N7OS
    Forma y color:Solid
    Peso molecular:567.66

    Ref: TM-T64016

  • Blixeprodil
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    Blixeprodil

    CAS:
    <p>Blixeprodil (GM-1020) is an orally active NMDA receptor antagonist with an affinity of Ki = 3.25 µM in rat cortical tissue. It inhibits NR1/2A-NMDAR-mediated currents in HEK293 cells with an IC50 of 1.192 µM. Blixeprodil demonstrates antidepressant effects in rat models and exhibits blood-brain barrier permeability.</p>
    Fórmula:C13H16FNO
    Forma y color:Solid
    Peso molecular:221.271

    Ref: TM-T206599

  • Logo de CymitQuimica
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    IAA65

    CAS:
    <p>IAA65 is a potent inhibitor of T-type calcium channels, exhibiting an IC50 value of 18.9 μM, and holds potential for use in epilepsy research [1].</p>
    Fórmula:C16H13F6NO2
    Forma y color:Solid
    Peso molecular:365.27

    Ref: TM-T61393

  • Logo de CymitQuimica
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    VU0463271 quarterhydrate

    <p>VU0463271 quarterhydrate is a potent KCC2 antagonist, with an IC 50 of 61 nM [1].</p>
    Fórmula:C19H20N4O2S2
    Forma y color:Solid
    Peso molecular:387

    Ref: TM-T61725

  • V-ATPase-IN-1
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    V-ATPase-IN-1

    CAS:
    <p>V-ATPase-IN-1 (Compound 3b-03) is an inhibitor of Vacuolar-type H+-ATPases (V-ATPase), exhibiting an inhibition constant (IC50) of 194.80 μM and effectively targeting the V-ATPase subunit A with a dissociation constant (Kd) of 0.803 μM. This compound demonstrates insecticidal activity against M. separata (LC50 = 2.64 mM), aiding in the development of chemical insecticides.</p>
    Fórmula:C21H20ClNO2
    Forma y color:Solid
    Peso molecular:353.84

    Ref: TM-T200467

  • (S)-Albuterol
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    (S)-Albuterol

    CAS:
    <p>(S)-Albuterol functions as a muscarinic receptor and phospholipase C activator, enhancing the intracellular free calcium concentration in airway smooth muscle cells.</p>
    Fórmula:C13H21NO3
    Forma y color:Solid
    Peso molecular:239.311

    Ref: TM-T206288

  • Lubeluzole dihydrochloride
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    Lubeluzole dihydrochloride

    CAS:
    <p>Lubeluzole (dihydrochloride) acts as a neuroprotective agent by blocking neuronal voltage-gated sodium channels and also affects cardiac sodium channels, exhibiting both tonic and blocking effects. This compound is considered promising in the research of antiarrhythmic agents.</p>
    Fórmula:C22H27Cl2F2N3O2S
    Forma y color:Solid
    Peso molecular:506.44

    Ref: TM-T200178

  • Kv7.2/Kv7.3 activator-1
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    Kv7.2/Kv7.3 activator-1

    CAS:
    <p>Kv7.2/Kv7.3 Activator-1 (compound 517) serves as a powerful activator of the Kv7.2/Kv7.3 channels, exhibiting an EC50 value of less than 1 µM. It holds potential for use in neurological disease research.</p>
    Fórmula:C19H22F2N4O
    Forma y color:Solid
    Peso molecular:360.40

    Ref: TM-T89880

  • PF-05661014
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    PF-05661014

    CAS:
    <p>PF-05661014, a demethylated analogue of PF-06526290, selectively inhibits Nav1.3 and Nav1.7 currents by stabilizing the inactivated state through interaction with the D4 VSD. This compound is utilized in research focused on sodium channel modulation.</p>
    Fórmula:C17H16N4O3S2
    Forma y color:Solid
    Peso molecular:388.46

    Ref: TM-T89885

  • CFTR corrector 16
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    CFTR corrector 16

    CAS:
    <p>CFTRcorrector 16 (Compound 39) is a corrector of the cystic fibrosis transmembrane conductance regulator (CFTR), utilized in the research of cystic fibrosis disease.</p>
    Fórmula:C27H26ClN5O2S
    Forma y color:Solid
    Peso molecular:520.05

    Ref: TM-T200113

  • SP100030 analogue 1
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    SP100030 analogue 1

    CAS:
    <p>SP100030 analogue 1 (compound 11) is a selective transcription activation (SITA) inhibitor within the SP100030 class, capable of inhibiting XPO1-dependent upregulation of IL2 in a Jurkat-based IL2-Luc reporter assay, with an EC50 of 137 nM.</p>
    Fórmula:C13H5ClF7N3O
    Forma y color:Solid
    Peso molecular:387.64

    Ref: TM-T89990

  • CFTR corrector 15
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    CFTR corrector 15

    CAS:
    <p>CFTR Corrector 15 (Compound 4172) serves as a corrector for cystic fibrosis transmembrane conductance regulator (CFTR). When used in combination with VX-809, it addresses the folding defects of F508del-CFTR. CFTR Corrector 15 is also applicable in the research of cystic fibrosis.</p>
    Fórmula:C24H22ClN5O2S
    Forma y color:Solid
    Peso molecular:479.98

    Ref: TM-T89966

  • (2S,3S,11bR)-Dihydrotetrabenazine
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    (2S,3S,11bR)-Dihydrotetrabenazine

    CAS:
    <p>(2S,3S,11bR)-Dihydrotetrabenazine ((2S,3S,11bR)-DHTBZ) is a highly selective inhibitor of vesicular monoamine transporter 2 (VMAT2) with a Ki value of 593 nM. It suppresses the vesicular transport of monoamine neurotransmitters, such as dopamine and serotonin, leading to reduced release into the synaptic cleft. This compound holds potential for research in Huntington's disease and other hyperkinetic movement disorders.</p>
    Fórmula:C19H29NO3
    Forma y color:Solid
    Peso molecular:319.44

    Ref: TM-T207440

  • S 0960
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    S 0960

    CAS:
    <p>S 0960 is a dimeric bile acid analogue, a specific inhibitor of the sodium-dependent bile salt transporter in the ileum, used in metabolic disease research.</p>
    Fórmula:C48H79NO8
    Pureza:99.32% - >99.99%
    Forma y color:Solid
    Peso molecular:798.14

    Ref: TM-T70688

  • Caramboxin
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    Caramboxin

    CAS:
    <p>Caramboxin, a neurotoxin, can induce acute kidney injury.</p>
    Fórmula:C11H13NO6
    Forma y color:Solid
    Peso molecular:255.22

    Ref: TM-T201088

  • Dehydroindapamide
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    Dehydroindapamide

    CAS:
    <p>Dehydroindapamide, an indole form of Indapamide, is utilized to quantify the turnover rate of Indapamide in CYP3A4, which is approximately 10 times higher than that of Indoline, with slightly enhanced affinity for CYP3A4.</p>
    Fórmula:C16H14ClN3O3S
    Forma y color:Solid
    Peso molecular:363.82

    Ref: TM-T200811

  • Perfluoroheptanesulfonic acid
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    Perfluoroheptanesulfonic acid

    CAS:
    <p>Perfluoroheptanesulfonic acid (1-Perfluoroheptanesulfonic acid; Perfluoroheptanesulphonic acid) is a perfluoroalkyl substance (PFAS). This compound has been detected in landfill leachate and has been shown to induce deformities in zebrafish larvae (EC50=168.1 μM). Exposure to PFHpS in fetuses can lead to reduced birth weight.</p>
    Fórmula:C7HF15O3S
    Forma y color:Solid
    Peso molecular:450.12

    Ref: TM-T200995