Canal TRP / TRPV
Los canales TRP (Receptor Potencial Transitorio), incluida la subfamilia TRPV, son un grupo de canales iónicos involucrados en diversos procesos sensoriales, como la sensación de temperatura, la percepción del dolor y la osmorregulación. Los canales TRP están ampliamente expresados en diferentes tejidos y desempeñan un papel en las respuestas fisiológicas a estímulos ambientales. Los canales TRPV, en particular, están involucrados en la detección de cambios de temperatura y están implicados en condiciones como el dolor crónico, la inflamación y el cáncer. En CymitQuimica, ofrecemos una gama completa de moduladores de canales TRP/TRPV para apoyar su investigación en biología sensorial, manejo del dolor y transducción de señales.
Se han encontrado 92 productos de "Canal TRP / TRPV"
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(Z)-Capsaicin
CAS:<p>(Z)-Capsaicin (Zucapsaicin) is a medication used to treat osteoarthritis of the knee and Others neuropathic pain.(Z)-Capsaicin is a synthetic cis isomer of</p>Fórmula:C18H27NO3Pureza:97.33% - 98.91%Forma y color:SolidPeso molecular:305.41TRPV4 agonist-1 free base
CAS:<p>TRPV4 agonist-1 free base (OUN67600) is an agonist of transient receptor potential vanilloid 4 (TRPV4;EC50 of 60 nM, in the hTRPV4 Ca2+ assay).</p>Fórmula:C25H22F2N4O2Pureza:99.79%Forma y color:SolidPeso molecular:448.46GFB-8438
CAS:<p>GFB-8438 is a potent and subtype selective inhibitor of TRPC5(IC50s of 0.18 and 0.29 μM of hTRPC5 and hTRPC4, respectively).</p>Fórmula:C16H14ClF3N4O2Pureza:99.58%Forma y color:SolidPeso molecular:386.76BI-749327
CAS:<p>BI-749327 is a high selectivity and orally bioavailable antagonist of TRPC6 (IC50s: 13 nM, 19 nM and 15 nM for mouse, human and guinea pig TRPC6).</p>Fórmula:C23H21F3N4O2Pureza:99.68%Forma y color:SolidPeso molecular:442.43IA-Alkyne
CAS:<p>IA-Alkyne: TRPC agonist, cysteine-reactivity probe, potential in respiratory infection study.</p>Fórmula:C8H12INOPureza:99.76%Forma y color:SolidPeso molecular:265.09Vocacapsaicin hydrochloride
CAS:<p>Vocacapsaicin hydrochloride (CA-008 hydrochloride) is a non-opioid TRPV1 agonist, a raw material for capsaicin, and is used for pain relief.</p>Fórmula:C26H42ClN3O4Pureza:99.66% - 99.80%Forma y color:SolidPeso molecular:496.08NGD-8243
CAS:<p>NGD-8243 (N-[4-(trifluoromethyl)phenyl]-7-[3-(trifluoromethyl)pyridin-2-yl]quinazolin-4-amine) is a TRPV1 inhibitor and can be used in studies for prevention</p>Fórmula:C21H12F6N4Pureza:95.26%Forma y color:SolidPeso molecular:434.34AP 18
CAS:<p>AP-18 is a potent and selective TRPA1 inhibitor.</p>Fórmula:C11H12ClNOPureza:99.85% - 99.96%Forma y color:SolidPeso molecular:209.67GSK2798745
CAS:<p>GSK2798745 is an orally active transient receptor potential vanilloid 4 (TRPV4) ion channel blocker (IC50s: 1.8 and 1.6 nM for hTRPV4 and rTRPV4).</p>Fórmula:C25H28N6O3Forma y color:SolidPeso molecular:460.53RN-1665
CAS:<p>RN-1665 is a potent and selective TRPV4 receptor antagonist.</p>Fórmula:C20H24F5N3O3S2Pureza:>99.99%Forma y color:SoildPeso molecular:513.54CBP-1008
<p>CBP-1008 is a dual-ligand peptide-drug conjugate (PDC) with MMAE, targeting folate receptor (FRα) and TRPV6. It exhibits high binding affinity to FRα and low affinity to TRPV6. CBP-1008 shows antitumor activity and can be utilized for research in advanced solid tumors such as colorectal cancer, breast cancer, non-small cell lung cancer, ovarian cancer, adrenocortical carcinoma, and follicular dendritic cell sarcoma.</p>Forma y color:Odour Solid(S)-ABT 102
CAS:<p>N-[(1S)-1H-inden-1-yl]-N'-indazol-4-ylurea is a strong TRPV1 blocker with a 123 nM IC50 against capsaicin.</p>Fórmula:C21H24N4OPureza:99.65% - 99.77%Forma y color:SoildPeso molecular:348.44PF-04745637
CAS:<p>PF-04745637 is a potent and selective TRPA1 antagonist with an IC50 of 17 nM[1].</p>Fórmula:C27H32ClF3N2O2Pureza:98.88% - 99.3%Forma y color:SolidPeso molecular:509TRPA1-IN-2
CAS:<p>TRPA1-IN-2 is a potent and orally active TRPA1 inhibitor with an IC50 value of 0.04 µM.TRPA1-IN-2 has anti-inflammatory activity.</p>Fórmula:C24H25F3N4OPureza:98.05%Forma y color:SoildPeso molecular:442.48Resolvin D2
CAS:<p>Resolvin D2 (RvD2) is a TRPV1 inhibitor and pro-ablative mediator with anti-inflammatory, anti-infective and pro-ablative effects.</p>Fórmula:C22H32O5Pureza:98%Forma y color:SolidPeso molecular:376.49TRPM8 antagonist 3
CAS:<p>TRPM8 antagonist 3 is a blocker of TRPM8 (IC50 = 11 nM).</p>Fórmula:C13H12N2O4SPureza:99.74%Forma y color:SolidPeso molecular:292.31Oleoyl Serotonin
CAS:<p>Oleoyl Serotonin is an antagonist of hTRPV1 with an IC50 of 2.57 μM.</p>Fórmula:C28H44N2O2Pureza:99.88%Forma y color:SolidPeso molecular:440.66L-R4W2
CAS:<p>Vanilloid TRPV1 (VR1) receptor antagonist peptide (IC50 ~ 0.1 μM); blocks Ca2+ currents in dorsal root ganglion neurons. Analgesic in vivo.</p>Fórmula:C46H71N21O6Pureza:98%Forma y color:SolidPeso molecular:1014.2Phenazopyridine
CAS:<p>Phenazopyridine is an orally administered azo dye with local analgesic effects on urinary tract infections,. against SARM1 and TRPM8.</p>Fórmula:C11H11N5Pureza:99.98%Forma y color:SolidPeso molecular:213.24BTD
CAS:<p>BTD is a TRPC5 activator that activates heteromeric channel complexes composed of TRPC5 and its closest relatives TRPC1 or TRPC4.</p>Fórmula:C24H33N3O4SForma y color:SolidPeso molecular:459.6
