Canal de potasio
Los canales de potasio son un grupo diverso de proteínas de membrana que facilitan el flujo de iones de potasio (K+) a través de la membrana celular. Estos canales desempeñan un papel crucial en el mantenimiento del potencial de membrana en reposo, la regulación del volumen celular y el control de la excitabilidad de las neuronas y las células musculares. Los canales de potasio están involucrados en varios procesos fisiológicos, incluyendo la regulación del ritmo cardíaco, la secreción de insulina y la liberación de neurotransmisores. La disfunción de los canales de potasio está relacionada con condiciones como arritmias, epilepsia e hipertensión. En CymitQuimica, ofrecemos una amplia gama de moduladores de canales de potasio para apoyar su investigación en electrofisiología, salud cardiovascular y neurobiología.
Se han encontrado 276 productos de "Canal de potasio"
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Rosuvastatin
CAS:<p>Rosuvastatin (ZD4522) is an inhibitor of HMG-CoA reductase (HMGCR). Rosuvastatin has hypolipidemic and antiatherosclerotic effects. Cost-effective and quality-assured.</p>Fórmula:C22H28FN3O6SPureza:95.24% - 99.8%Forma y color:SolidPeso molecular:481.54Levosimendan
CAS:<p>Levosimendan (OR1259) is a calcium sensitizer for acute heart failure, enhancing cardiac contractility without raising calcium levels.</p>Fórmula:C14H12N6OPureza:99.37% - 99.91%Forma y color:Yellow Crystalline PowderPeso molecular:280.28QO-40
CAS:<p>QO-40 is a KCNQ2/3 potassium channels activator.</p>Fórmula:C18H11ClF3N3OPureza:99.57%Forma y color:SolidPeso molecular:377.75H3B-120
CAS:<p>H3B-120: selective, competitive CPS1 inhibitor with anti-cancer properties. IC50: 1.5 μM, Ki: 1.4 μM.</p>Fórmula:C19H24N4O2SPureza:99.03% - 99.2%Forma y color:SolidPeso molecular:372.48CLP290
CAS:<p>CLP290 is an activator of the neuron-specific K+-Cl cotransporter KCC2 and displays potential for the treatment of a wide range of neurological and psychiatric</p>Fórmula:C19H21FN4O3SPureza:99.93% - >99.99%Forma y color:SolidPeso molecular:404.46BMS-191011
CAS:<p>BMS-191011 (BMS-A) is an activator of large-conductance calcium-activated potassium (BKCa) channels ,effective in stroke models</p>Fórmula:C16H10ClF3N2O3Pureza:97.43%Forma y color:SolidPeso molecular:370.71Tetrandrine
CAS:<p>Tetrandrine (Sinomenine A) is a naturally occurring biphenylisoquinoline alkaloid, a calcium channel inhibitor. Cost-effective and quality-assured.</p>Fórmula:C38H42N2O6Pureza:99.61% - 99.94%Forma y color:White SolidPeso molecular:622.75BL-1249
CAS:<p>BL-1249 is a selective and potent non-steroidal potassium channel activator with anti-inflammatory activity that activates K2P2.1 (TREK-1) and K2P10.1 (TREK-2).</p>Fórmula:C17H17N5Pureza:98% - 98.25%Forma y color:SolidPeso molecular:291.35VU590
CAS:<p>VU590 is an inhibitor of extrarenal medullary potassium ROMK.VU590 inhibits Kir7.1 and modulates uterine myometrial contractility and melanocortin signalling.</p>Fórmula:C24H32N4O7Pureza:98.06%Forma y color:SolidPeso molecular:488.53HUP30
CAS:<p>HUP30 is a potent vasodilating agent. HUP30 can stimulate soluble guanylyl cyclase, activate K+ channels, and block extracellular Ca2+ influx.</p>Fórmula:C14H15N3O3SPureza:99.96%Forma y color:SolidPeso molecular:305.35Doxapram
CAS:<p>Doxapram (Dopram) is a respiratory stimulant that inhibits TASK-1, TASK-3, and TASK-1/TASK-3 heterodimer channels.</p>Fórmula:C24H30N2O2Pureza:99.42%Forma y color:SolidPeso molecular:378.51Dofetilide D4
CAS:<p>Dofetilide D4 (UK 68789 D4), a deuterium-labeled version of Dofetilide, is categorized as a Class III antiarrhythmic medication.</p>Fórmula:C19H27N3O5S2Pureza:98%Forma y color:SolidPeso molecular:445.59Repaglinide D5
CAS:<p>Repaglinide D5 is deuterium labeled Repaglinide. Repaglinide is an insulin secretagogue for treatment type-2 diabetes mellitus.</p>Fórmula:C27H36N2O4Pureza:98%Forma y color:SolidPeso molecular:457.62LY 303511
CAS:<p>LY303511, an inactive analogue of LY294002, is a mTOR inhibitor and no inhibition for PI3-K.</p>Fórmula:C19H18N2O2Pureza:98%Forma y color:SolidPeso molecular:306.36Meclofenamic acid
CAS:<p>Meclofenamic acid: non-selective gap-junction blocker, FTO inhibitor, anti-inflammatory.</p>Fórmula:C14H11Cl2NO2Pureza:98%Forma y color:SolidPeso molecular:296.15AVE-0118
CAS:<p>AVE-0118 is a potassium channel blocker and suppresses persistent atrial fibrillation.</p>Fórmula:C30H29N3O3Pureza:97.04% - 98.93%Forma y color:SolidPeso molecular:479.57ML402
CAS:<p>ML402 (ZINC3671497) is an activator of TREK-1 and TREK-2 with EC50s of 13.7 μM and 5.9 μM.</p>Fórmula:C14H14ClNO2SPureza:99.71%Forma y color:SolidPeso molecular:295.78ICA
CAS:<p>ICA (N-[4-(2-Pyridinyl)-2-thiazolyl]-2-pyridinamine) is a SK channel inhibitor and exhibits antileishmanial activity (IC50: 2.1 µM).</p>Fórmula:C13H10N4SPureza:99.68%Forma y color:SolidPeso molecular:254.31UK 78282 hydrochloride
CAS:<p>UK-78282 hydrochloride, a Kv1.3 blocker.UK-78282 hydrochloride inhibits Kv1.3 voltage-gated potassium channels and suppresses human T cell activation.</p>Fórmula:C29H36ClNO2Pureza:99.68%Forma y color:SolidPeso molecular:466.05TWIK-1/TREK-1-IN-2
CAS:<p>TWIK-1/TREK-1-IN-2 (Compound 2g) serves as an inhibitor of both TWIK-1 and TREK-1, targeting the TREK-1 homodimer and TWIK-1/TREK-1 heterodimer with IC50 values</p>Fórmula:C20H29F3N2O2Pureza:98%Forma y color:SolidPeso molecular:386.45
