
Canal de potasio
Los canales de potasio son un grupo diverso de proteínas de membrana que facilitan el flujo de iones de potasio (K+) a través de la membrana celular. Estos canales desempeñan un papel crucial en el mantenimiento del potencial de membrana en reposo, la regulación del volumen celular y el control de la excitabilidad de las neuronas y las células musculares. Los canales de potasio están involucrados en varios procesos fisiológicos, incluyendo la regulación del ritmo cardíaco, la secreción de insulina y la liberación de neurotransmisores. La disfunción de los canales de potasio está relacionada con condiciones como arritmias, epilepsia e hipertensión. En CymitQuimica, ofrecemos una amplia gama de moduladores de canales de potasio para apoyar su investigación en electrofisiología, salud cardiovascular y neurobiología.
Se han encontrado 276 productos de "Canal de potasio"
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MK-0448
CAS:<p>MK-0448 is a novel and selective blocker of the Kv1.5 (KCNA5) channel, a key channel involved in cardiac repolarization current I Kur.</p>Fórmula:C24H21FN4O2SPureza:99.25% - 99.79%Forma y color:SolidPeso molecular:448.51CyPPA
CAS:<p>CyPPA enhances SK channels, reducing firing rate and extending apamin-sensitive afterhyperpolarization.</p>Fórmula:C16H23N5Pureza:99.88%Forma y color:SolidPeso molecular:285.39Sipatrigine
CAS:<p>Sipatrigine (619C89) is an inhibitor of glutamate release, TREK ion channels, TRESK channels, sodium channels, and calcium channels.</p>Fórmula:C15H16Cl3N5Pureza:98.64% - 99.77%Forma y color:SolidPeso molecular:372.68RL648_81
CAS:<p>RL648_81 is a selective activator of KCNQ2/3 channels (EC50 = 190 nM). RL648_81 can be used in studies about neuronal hyperexcitability neurologic disorders.</p>Fórmula:C17H17F4N3O2Pureza:99.82%Forma y color:SolidPeso molecular:371.33SKA-111
CAS:<p>SKA-111 activates KCa3.1 potassium channels, modulates membrane potential in endothelial cells, and dilates rat coronary arteries.</p>Fórmula:C12H10N2SPureza:99.9%Forma y color:SolidPeso molecular:214.29ZTZ240
CAS:<p>ZTZ240 is a KCNQ2 channel activator used in the study of epilepsy.</p>Fórmula:C12H8ClFN2OPureza:99.89%Forma y color:SolidPeso molecular:250.66ZM 226600
CAS:<p>ZM 226600 is an ATP-sensitive potassium channel opener with an EC50 value of 500 nM. ZM226600 has an inhibitory effect on spontaneous bladder activity.</p>Fórmula:C16H14F3NO4SPureza:99.87%Forma y color:SolidPeso molecular:373.35PD-118057
CAS:<p>PD-118057, a potent hERG activator, may treat long QT syndrome and heart failure without hERG activity inhibition.</p>Fórmula:C21H17Cl2NO2Pureza:99.16% - 99.97%Forma y color:SolidPeso molecular:386.27UK 66914
CAS:<p>UK 66914 is a K(+) channel blocker for the study of cardiac arrhythmias.</p>Fórmula:C18H24N4O3SPureza:99.75%Forma y color:SolidPeso molecular:376.47(+)-KCC2 blocker 1
CAS:<p>(+)-KCC2 blocker 1 is a selective blocker of KCC2 (IC50 = 0.4 μM).</p>Fórmula:C22H25NO5SPureza:99.88%Forma y color:SolidPeso molecular:415.5GW 542573X
CAS:<p>GW 542573X is a potent and selective small molecule Ca2+-activated K+ 2 (SK2) channel activator.GW 542573X induces a leftward shift in the Ca2+ response curve</p>Fórmula:C19H28N2O5Pureza:99.91%Forma y color:SolidPeso molecular:364.44XE991
CAS:<p>XE991 is a Kv7 (KCNQ) channel blocker.XE 991 dihydrochloride inhibits Kv7.1 (KCNQ1) and M-current and can be used in the study of neurological disorders.</p>Fórmula:C26H20N2OPureza:98.87%Forma y color:SolidPeso molecular:376.45TWIK-1/TREK-1-IN-3
CAS:<p>TWIK-1/TREK-1-IN-3 is a potassium channel TREK-1 inhibitor TWIK-1/TREK-1-IN-3 has antidepressant activity and can be used to study depression.</p>Fórmula:C19H27F3N2O2Pureza:99.04%Forma y color:SolidPeso molecular:372.43IKs124
CAS:<p>IKs124 is a KCNE2/KCNQ1 potassium channel blocker, for hKCNE1 and hKCNE3, and can be used to study peptic ulcers.</p>Fórmula:C18H26N2O3SPureza:99.53%Forma y color:SolidPeso molecular:350.48KT-362 fumarate
CAS:<p>KT-362 fumarate, a novel antagonist of Ca, K, and Na channels, induces vasodilation and relaxes rabbit arterial strips.</p>Fórmula:C26H32N2O7SPureza:99.75% - 99.98%Forma y color:SolidPeso molecular:516.61JNJ-26489112
CAS:<p>JNJ-26489112 is a CNS-active agent and an inhibitor of voltage-gated Na+ channels and N-type Ca2+ channels.</p>Fórmula:C9H11ClN2O4SPureza:99.31%Forma y color:SolidPeso molecular:278.71Linaprazan
CAS:<p>Linaprazan (AZD0865) inhibits gastric H+,K+-ATPase by K+-competitive binding with an IC50 of 1.0 μM.</p>Fórmula:C21H26N4O2Pureza:99.54%Forma y color:SolidPeso molecular:366.46DPO-1
CAS:<p>DPO-1 可以高效抑制电压门控钾离子通道Kv1.5,也可以阻断超快速延迟整流钾电流。它能够预防房性心律失常。</p>Fórmula:C22H29OPPureza:99.78%Forma y color:SolidPeso molecular:340.44Clobutinol hydrochloride
CAS:<p>Clobutinol hydrochloride, an antitussive agent, influences heart rate and blood pressure, and is utilized in cough-related research [1] [2] [3].</p>Fórmula:C14H23Cl2NOPureza:98%Forma y color:SolidPeso molecular:292.25VU0463271
CAS:<p>VU0463271: KCC2 antagonist, IC50 61 nM, >100x selective over NKCC1, inactive on other GPCRs, channels, transporters.</p>Fórmula:C19H18N4OS2Pureza:97.84% - 99.55%Forma y color:SolidPeso molecular:382.5
