Canal de potasio
Los canales de potasio son un grupo diverso de proteínas de membrana que facilitan el flujo de iones de potasio (K+) a través de la membrana celular. Estos canales desempeñan un papel crucial en el mantenimiento del potencial de membrana en reposo, la regulación del volumen celular y el control de la excitabilidad de las neuronas y las células musculares. Los canales de potasio están involucrados en varios procesos fisiológicos, incluyendo la regulación del ritmo cardíaco, la secreción de insulina y la liberación de neurotransmisores. La disfunción de los canales de potasio está relacionada con condiciones como arritmias, epilepsia e hipertensión. En CymitQuimica, ofrecemos una amplia gama de moduladores de canales de potasio para apoyar su investigación en electrofisiología, salud cardiovascular y neurobiología.
Se han encontrado 276 productos de "Canal de potasio"
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
11-deoxy-PGF2a
CAS:<p>11-deoxy-PGF2a is a thromboxane A2 receptor agonist that partially alleviates crowding in Lpar3(−/−) female embryos and induces smooth muscle contraction</p>Fórmula:C20H34O4Forma y color:SolidPeso molecular:338.48Glibornuride
CAS:<p>Glibornuride is a blocker of ATP-sensitive K+ channel(pKi: 5.75).</p>Fórmula:C18H26N2O4SPureza:99.5%Forma y color:SolidPeso molecular:366.48Sigma-1 receptor antagonist 3
CAS:<p>Sigma-1 receptor antagonist 3 is a more potent and selective antagonist of Sigma-1 (σ1) receptor (Ki = 1.14 nM) than σ2 receptor(Ki = 1239 nM).</p>Fórmula:C19H23ClFN3OPureza:99.95%Forma y color:SolidPeso molecular:363.86CLP257
CAS:<p>CLP257 is a selective K+-Cl− cotransporter KCC2 activator (EC50: 616 nM) and it is inactive against NKCC1, GABAA receptors, KCC1, KCC3 or KCC4.</p>Fórmula:C14H14FN3O2SPureza:99.5%Forma y color:SolidPeso molecular:307.34MCHR1 antagonist 2
CAS:<p>MCHR1 antagonist 2 is an antagonist of melanin-concentratin hormone receptor 1(MCH1-R, IC50 = 65 nM) and also inhibits hERG.</p>Fórmula:C23H21FN2O5Pureza:98.29%Forma y color:SolidPeso molecular:424.42P-1075
CAS:<p>P-1075 activates SUR2-KIR6 channels at 45 nM; may open mitoKATP channels and protect the heart.</p>Fórmula:C12H17N5Pureza:99.85%Forma y color:SolidPeso molecular:231.3C 101248
CAS:<p>C 101248 (KCNK13-IN-1) is a selective and potent tandem pore halogen inhibitor of K+ channel 1 (THIK-1) inhibitor and a human and mouse KCNK13 inhibitor.</p>Fórmula:C15H12N6OPureza:99.14% - 99.31%Forma y color:SolidPeso molecular:292.3Kv3 modulator 1
CAS:<p>Kv3 modulator 1 is a voltage-gated potassium channel Kv3 modulator that can be used to study neurologic-level diseases.</p>Fórmula:C20H20N4O4Pureza:99.41%Forma y color:SolidPeso molecular:380.4Kv7.2/Kv7.3 agonist 1
CAS:<p>Kv7.2/Kv7.3 agonist 1 (Compound 16) is an orally effective agonist for the KV7.2/7.3 channels (KV7.2/7.3 channel/KCNQ2/3) with an EC50 of 1.03 μM. This compound demonstrates analgesic effects in mouse models of chronic constriction injury (CCI) and Streptozotocin-induced diabetic peripheral neuropathy (DPNP), with ED50 values of 12.02 mg/kg and 9.63 mg/kg, respectively.</p>Fórmula:C14H14FN3O2Forma y color:SolidPeso molecular:275.28KCC2 Modulator-2
CAS:<p>KCC2 Modulator-2 (example 53) is a regulator of KCC2 with an EC50 of 0.215 μM. It is used in the research of neurological diseases.</p>Fórmula:C35H45N5O3Forma y color:SolidPeso molecular:583.76KV1.3-IN-2
CAS:<p>KV1.3-IN-2 (Compound I) selectively inhibits the kv1.3 potassium channel without affecting the hERG channel. It is applicable in research related to immune-associated diseases such as psoriasis, rheumatoid arthritis, and systemic lupus erythematosus.</p>Fórmula:C16H23ClN2O4Forma y color:SolidPeso molecular:342.818cis-KV1.3-IN-1
CAS:<p>cis-KV1.3-IN-1, also known as Compound cis-18, is the cis-isomer of KV1.3-IN-1 and functions as an inhibitor of the KV1.3 channel. In Xenopus laevis oocytes expressing human hKV1.3, cis-KV1.3-IN-1 (10 μM) achieves an inhibition rate of 25.53% against KV1.3.</p>Fórmula:C23H30N2O4SForma y color:SolidPeso molecular:430.56Kv7.2/Kv7.3 modulator-1
CAS:<p>Kv7.2/Kv7.3 modulator-1 (compound 6a) acts as a modulator for Kv7.2/Kv7.3 channels, with a pEC50 value of 7.96 for opening these channels. Kv7.2/Kv7.3 modulator-1 is applicable in research related to epilepsy, depression, brain injury, and pain.</p>Fórmula:C20H21F4N3O3Forma y color:SolidPeso molecular:427.393Opakalim
CAS:<p>Opakalim is an activator of potassium channels (potassium channel) and exhibits anticonvulsant activity.</p>Fórmula:C18H22F2N4OForma y color:SolidPeso molecular:348.39Kv7.2/Kv7.3 activator-1
CAS:<p>Kv7.2/Kv7.3 Activator-1 (compound 517) serves as a powerful activator of the Kv7.2/Kv7.3 channels, exhibiting an EC50 value of less than 1 µM. It holds potential for use in neurological disease research.</p>Fórmula:C19H22F2N4OForma y color:SolidPeso molecular:360.40Indapamide
CAS:<p>Indapamide (Noranat) is a non-thiazide sulphonamide diuretic compound, generally used in the treatment of hypertension, as well as decompensated cardiac failure.</p>Fórmula:C16H16ClN3O3SPureza:98.97% - 99.83%Forma y color:SolidPeso molecular:365.83Ref: TM-T1498
Producto descatalogado
