Canal de potasio
Los canales de potasio son un grupo diverso de proteínas de membrana que facilitan el flujo de iones de potasio (K+) a través de la membrana celular. Estos canales desempeñan un papel crucial en el mantenimiento del potencial de membrana en reposo, la regulación del volumen celular y el control de la excitabilidad de las neuronas y las células musculares. Los canales de potasio están involucrados en varios procesos fisiológicos, incluyendo la regulación del ritmo cardíaco, la secreción de insulina y la liberación de neurotransmisores. La disfunción de los canales de potasio está relacionada con condiciones como arritmias, epilepsia e hipertensión. En CymitQuimica, ofrecemos una amplia gama de moduladores de canales de potasio para apoyar su investigación en electrofisiología, salud cardiovascular y neurobiología.
Se han encontrado 276 productos de "Canal de potasio"
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Gliclazide
CAS:<p>Gliclazide (SE1702), an oral antihyperglycemic agent, belongs to the sulfonylurea class of insulin secretagogues, which act by stimulating beta-cells of the</p>Fórmula:C15H21N3O3SPureza:99.58%Forma y color:SolidPeso molecular:323.41NS8593 hydrochloride
CAS:<p>NS8593 hydrochloride (NS8593 HCl) is a potent and selective inhibitor of small conductance Ca2+-activated K+ channels (SK channels) .</p>Fórmula:C17H18ClN3Pureza:99.77%Forma y color:SolidPeso molecular:299.8N-Acetylprocainamide
CAS:<p>N-Acetylprocainamide (NAPA), the N-acetylated metabolite of Procainamide, is a Class III antiarrhythmic agent, while procainamide is a Class Ia antiarrhythmic</p>Fórmula:C15H23N3O2Pureza:99.65% - 99.74%Forma y color:SolidPeso molecular:277.36Minocycline hydrochloride
CAS:<p>Minocycline HCl: tetracycline antibiotic, treats bacterial infections and acne, may cause acute or chronic hepatitis.</p>Fórmula:C23H28ClN3O7Pureza:99.28% - >99.99%Forma y color:Bright Yellow-Orange Amorphous Solid Crystalline YellowPeso molecular:493.94Dequalinium chloride
CAS:<p>Dequalinium chloride: topical bacteriostat, blocks apamin-sensitive K+ channels, used for wounds, oral infections, potential antifungal, risk of skin ulcers.</p>Fórmula:C30H40Cl2N4Pureza:99.79% - 99.9%Forma y color:SolidPeso molecular:527.59Bupivacaine hydrochloride
CAS:<p>Bupivacaine hydrochloride (Vivacaine) is a long-lasting, amide local anesthetic that blocks sodium channels, inhibiting nerve impulses and sensation.</p>Fórmula:C18H28N2O·HClPureza:99.9% - >99.99%Forma y color:SolidPeso molecular:324.89Flindokalner
CAS:<p>Flindokalner (BMS-204352) modulates potassium channels, enhances Kv7 subtypes and BKca, inhibits Kv7.1 (Ki=3.7μM), GABAA; has anxiolytic effects in vivo.</p>Fórmula:C16H10ClF4NO2Pureza:99.96%Forma y color:SolidPeso molecular:359.7Mefloquine
CAS:<p>Mefloquine (Ro 215998), a quinoline antimalarial agent, is an anti-SARS-CoV-2 entry inhibitor.</p>Fórmula:C17H16F6N2OPureza:99.89%Forma y color:SolidPeso molecular:378.31Astemizole
CAS:<p>Astemizole (Laridal) is a long-acting antihistamine for allergies like rhinitis and asthma, with fewer anticholinergic effects.</p>Fórmula:C28H31FN4OPureza:98.24% - 99.67%Forma y color:White Crystals SolidPeso molecular:458.57Linopirdine
CAS:<p>Linopirdine (DuP 996) is a TRPV1 agonist.</p>Fórmula:C26H21N3OPureza:99.45% - 99.78%Forma y color:SolidPeso molecular:391.46Propafenone
CAS:<p>Propafenone: a drug for ventricular arrhythmias with mild beta-blocker activity, prolongs refractory period, and reduces heart automaticity.</p>Fórmula:C21H27NO3Pureza:99.02%Forma y color:SolidPeso molecular:341.44Phenformin hydrochloride
CAS:<p>Phenformin hydrochloride (Phenformin HCl) is an agent belonging to the biguanide class of antidiabetics with antihyperglycemic activity.</p>Fórmula:C10H16ClN5Pureza:97.11% - 99.80%Forma y color:Lactic AcidosisPeso molecular:241.72Brompheniramine maleate
CAS:<p>Brompheniramine maleate (Dimotane) is an antagonist against histamine H1 receptors.</p>Fórmula:C16H19BrN2·C4H4O4Pureza:99.80%Forma y color:Crystal PowderPeso molecular:435.31Quinidine hydrochloride monohydrate
CAS:<p>Quinidine hydrochloride monohydrate is an optical isomer of quinine. Quinidine prolongs cellular action potential and decreases automaticity.</p>Fórmula:C20H27ClN2O3Pureza:94.4% - 99.68%Forma y color:SolidPeso molecular:378.89ML418
CAS:<p>ML418 is a potent, selective and CNS penetrating Kir7.1 potassium channel blocker (IC50 = 310 nM), and also potently inhibits Kir6.2/SUR1.</p>Fórmula:C19H24ClN3O3Pureza:99.3%Forma y color:SolidPeso molecular:377.87Tannic acid
CAS:<p>Tannic acid (Gallotannic acid) is a novel hERG channel blocker.</p>Fórmula:C76H52O46Pureza:AR - ARForma y color:Light Yellow To Light Brown Solid Solid Particulate/PowderPeso molecular:1701.2Doxapram hydrochloride hydrate
CAS:<p>Doxapram hydrochloride hydrate (Doxapram HCl) inhibits TASK-1, TASK-3, TASK-1/TASK-3 heterodimeric channel function with EC50 of 0.41, 37, 9 μM, respectively.</p>Fórmula:C24H33ClN2O3C24H30N2O2·ClH·H2OPureza:99.64% - >99.99%Forma y color:SolidPeso molecular:432.99Butamben
CAS:<p>Butamben (Butyl 4-aminobenzoate) is a long-duration local anesthetic used for the treatment of chronic pain.</p>Fórmula:C11H15NO2Pureza:99.43%Forma y color:Crystals From Alc Physical Description Yellow Powder Insoluble In Water (Ntp 1992)Peso molecular:193.24VU591 hydrochloride
CAS:<p>VU591 hydrochloride is a selective Kir1.1 (ROMK) blocker with IC50 of 0.24 μM, not affecting Kir7.1, Kir2.1, Kir2.3, or Kir4.1, similar to VU 590.</p>Fórmula:C16H13ClN6O5Pureza:98.93% - 99.22%Forma y color:SolidPeso molecular:404.76Ifenprodil Tartrate
CAS:<p>Ifenprodil is a selective NMDA receptor (glutamate) antagonist.</p>Fórmula:C21H27NO2C4H6O6Pureza:99.02% - 99.55%Forma y color:SolidPeso molecular:400.491-EBIO
CAS:<p>1-EBIO (1-EBIO) is a calium channel agonist.</p>Fórmula:C9H10N2OPureza:98.75%Forma y color:SolidPeso molecular:162.19NS3623
CAS:<p>NS3623 is an activator of human ether-a-go-go-related gene potassium channels.</p>Fórmula:C15H10BrF3N6OPureza:97.06%Forma y color:SolidPeso molecular:427.18Tipepidine hydrochloride
CAS:<p>Tipepidine hydrochloride: reversible DA D2 receptor inhibitor, IC50 7.0 μM, with antidepressant effects.</p>Fórmula:C15H18ClNS2Pureza:99.97%Forma y color:SolidPeso molecular:311.89Repaglinide
CAS:<p>Repaglinide, a benzoic acid derivative, stimulates insulin, treats type 2 diabetes, and may rarely cause acute liver injury.</p>Fórmula:C27H36N2O4Pureza:99.73% - >99.99%Forma y color:White To Off-White SolidPeso molecular:452.59Glipizide
CAS:<p>Glipizide (CP 28720) is a short-acting, second-generation sulfonylurea with hypoglycemic activity.</p>Fórmula:C21H27N5O4SPureza:99.67% - 99.75%Forma y color:SolidPeso molecular:445.54NS13001
CAS:<p>NS13001, an oral SK channel modulator, shows promise for SCA2 therapy; EC50: 1.8 µM (SK2), 0.14 µM (SK3).</p>Fórmula:C17H16ClN7Pureza:99.55%Forma y color:SolidPeso molecular:353.81Mefloquine hydrochloride
CAS:<p>Mefloquine hydrochloride (Mefloquin hydrochloride) is a quinoline derivative used for the prevention and therapy of P. falciparum malaria.</p>Fórmula:C17H17ClF6N2OPureza:99% - 99.74%Forma y color:Off-White To Yellow SolidPeso molecular:414.77Dronedarone hydrochloride
CAS:<p>Dronedarone hydrochloride (SR33589) is an amiodarone analog which has an effective and promising treatment for Atrial fibrillation.</p>Fórmula:C31H44N2O5S·HClPureza:99.61%Forma y color:SolidPeso molecular:593.22VU0134992 hydrochloride
CAS:<p>VU0134992 hydrochloride is the first subtype-preferring, orally active and selective blocker of Kir4.1 potassium channel pore(IC50 : 0.97 μM).</p>Fórmula:C20H32BrClN2O2Pureza:>99.99%Forma y color:SolidPeso molecular:447.84BMS-394136
CAS:<p>BMS-394136 (BMS 394136) is a KV1.5 antagonist for the treatment of cardiovascular diseases such as arrhythmias and atrial fibrillation.</p>Fórmula:C24H21Cl2FN4OPureza:98.19% - 98.67%Forma y color:SolidPeso molecular:471.35IK1 inhibitor PA-6
CAS:<p>IK1 inhibitor PA-6 (PA-6) is a selective and potent inhibitor of IK1 (KIR2.x ion-channel-carried inward rectifier current)(IC50 of 12-15 nM for human and mouse</p>Fórmula:C31H32N4O2Pureza:98.9%Forma y color:SolidPeso molecular:492.61Eleclazine hydrochloride
CAS:<p>Eleclazine hydrochloride (GS 6615 hydrochloride) is a novel inhibitor of late Na+ current (IC50: 0.7 uM).</p>Fórmula:C21H17ClF3N3O3Pureza:99.86%Forma y color:SolidPeso molecular:451.83Hydroxyhexamide
CAS:<p>Hydroxyhexamide ((±)-Hydroxyhexamid) is a pharmacologically active metabolite of Acetohexamide, used as a hypoglycemic agent.</p>Fórmula:C15H22N2O4SPureza:98.91%Forma y color:SolidPeso molecular:326.41Ketanserin
CAS:<p>Ketanserin: quinazoline derivative, 5-HT2 receptor antagonist, may lower blood pressure and inhibit blood clots.</p>Fórmula:C22H22FN3O3Pureza:99.19% - 99.73%Forma y color:SolidPeso molecular:395.43Ropivacaine
CAS:<p>Ropivacaine (LEA-103 HCl) is a local anaesthetic drug belonging to the amino amide group.</p>Fórmula:C17H26N2OPureza:97.75% - >99.99%Forma y color:SolidPeso molecular:274.40Ropivacaine hydrochloride
CAS:<p>Ropivacaine hydrochloride (Ropivacaine monohydrochloride) is the hydrochloride salt of ropivacaine, a local anesthetic of the amide type with analgesic activity</p>Fórmula:C17H26N2O·HClPureza:99.85% - 99.95%Forma y color:SolidPeso molecular:310.86Quinine
CAS:<p>Quinine is a natural cinchona alkaloid that has been used for centuries in the prevention and therapy of malaria.</p>Fórmula:C20H24N2O2Pureza:99.93% - 99.97%Forma y color:White Solid PowderPeso molecular:324.42Oxybutynin
CAS:<p>Oxybutynin (Ditropan) is a synthetic anticholinergic agent that is used for treatment of urinary incontinence and overactive bladder syndrome.</p>Fórmula:C22H31NO3Pureza:97.81% - 99.57%Forma y color:White To Off-White Crystalline PowderPeso molecular:357.49Terfenadine
CAS:<p>Terfenadine, metabolized to fexofenadine by CYP3A4, is a non-sedative antihistamine targeting H1 receptors.</p>Fórmula:C32H41NO2Pureza:98.76% - 99.75%Forma y color:SolidPeso molecular:471.67Disopyramide
CAS:<p>Disopyramide, or Triombrin, a class I anti-arrhythmic with membrane-stabilizing effects, has heart depressant, anticholinergic, and anesthetic properties.</p>Fórmula:C21H29N3OPureza:99.62%Forma y color:SolidPeso molecular:339.47Glibenclamide
CAS:<p>Glibenclamide (Glyburide) is an antidiabetic sulfonylurea derivative with actions similar to those of chlorpropamide.</p>Fórmula:C23H28ClN3O5SPureza:99.05% - 99.75%Forma y color:SolidPeso molecular:494.00Clofilium tosylate
CAS:<p>Clofilium tosylate is a potassium channel blocker, induces apoptosis on human promyelocytic leukemia (HL-60) cells.</p>Fórmula:C28H44ClNO3SPureza:99.68%Forma y color:SolidPeso molecular:510.17Minoxidil
CAS:<p>Minoxidil (U10858) is an orally administered vasodilator with hair growth stimulatory and antihypertensive effects.</p>Fórmula:C9H15N5OPureza:99.885% - >99.99%Forma y color:Crystals From Methanol-Acetonitrile SolidPeso molecular:209.25DCPIB
CAS:<p>DCPIB, a known specific and potent inhibitor of volume-regulated anion channels (VRAC),DCPIB displayed superior selectivity toward TRESK with an IC50 of 0.14 μM</p>Fórmula:C22H28Cl2O4Pureza:99.79% - 99.87%Forma y color:SolidPeso molecular:427.36VU6036720
<p>VU6036720 is a potent and selective inhibitor of the isomeric Kir4.1/5.1.VU6036720 inhibits Kir4.1/5.1 activity by decreasing the channel open-circuit</p>Fórmula:C20H22ClFN4O2SPureza:98.1%Forma y color:SoildPeso molecular:436.93Linoleoyl glycine
CAS:<p>Linoleoyl glycine activates hKCNQ1/hKCNE1 channels, has analgesic properties, and is found in skin, spinal cord, and brain.</p>Fórmula:C20H35NO3Pureza:98.96%Forma y color:SolidPeso molecular:337.5AZD 7009
CAS:<p>AZD 7009 is a novel antiarrhythmic compound that inhibits the sodium current of hNav1.5 in CHO K1 cells with an IC50 of 11 uM.</p>Fórmula:C23H34N4O5Pureza:98.42% - 98.51%Forma y color:SoildPeso molecular:446.544-Aminopyridine
CAS:<p>4-Aminopyridine (Dalfampridine) is a nonselective potassium (K+) channel blocker that binds to the cytoplasmic side of the cell membrane.</p>Fórmula:C5H6N2Pureza:91.61%Forma y color:SolidPeso molecular:94.11Miconazole
CAS:<p>Miconazole (R18134) is an imidazole antifungal agent that is used topically and by intravenous infusion.</p>Fórmula:C18H14Cl4N2OPureza:98% - >99.99%Forma y color:SolidPeso molecular:416.13Amiodarone hydrochloride
CAS:<p>Amiodarone HCl: Antianginal, class III antiarrhythmic. Lengthens heart muscle action, slows heart rate, reduces vascular resistance.</p>Fórmula:C25H29I2NO3·HClPureza:99.82% - ≥95%Forma y color:White To Cream Crystalline PowderPeso molecular:681.78
