Canal de potasio
Los canales de potasio son un grupo diverso de proteínas de membrana que facilitan el flujo de iones de potasio (K+) a través de la membrana celular. Estos canales desempeñan un papel crucial en el mantenimiento del potencial de membrana en reposo, la regulación del volumen celular y el control de la excitabilidad de las neuronas y las células musculares. Los canales de potasio están involucrados en varios procesos fisiológicos, incluyendo la regulación del ritmo cardíaco, la secreción de insulina y la liberación de neurotransmisores. La disfunción de los canales de potasio está relacionada con condiciones como arritmias, epilepsia e hipertensión. En CymitQuimica, ofrecemos una amplia gama de moduladores de canales de potasio para apoyar su investigación en electrofisiología, salud cardiovascular y neurobiología.
Se han encontrado 280 productos de "Canal de potasio"
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Linopirdine
CAS:Linopirdine (DuP 996) is a TRPV1 agonist.Fórmula:C26H21N3OPureza:99.45% - 99.78%Forma y color:SolidPeso molecular:391.46Minocycline hydrochloride
CAS:Minocycline HCl: tetracycline antibiotic, treats bacterial infections and acne, may cause acute or chronic hepatitis.Fórmula:C23H28ClN3O7Pureza:99.28% - >99.99%Forma y color:Bright Yellow-Orange Amorphous Solid Crystalline YellowPeso molecular:493.94Eleclazine hydrochloride
CAS:Eleclazine hydrochloride (GS 6615 hydrochloride) is a novel inhibitor of late Na+ current (IC50: 0.7 uM).Fórmula:C21H17ClF3N3O3Pureza:99.86%Forma y color:SolidPeso molecular:451.83Ketanserin
CAS:Ketanserin: quinazoline derivative, 5-HT2 receptor antagonist, may lower blood pressure and inhibit blood clots.Fórmula:C22H22FN3O3Pureza:99.19% - 99.73%Forma y color:SolidPeso molecular:395.43Hydroxyhexamide
CAS:Hydroxyhexamide ((±)-Hydroxyhexamid) is a pharmacologically active metabolite of Acetohexamide, used as a hypoglycemic agent.Fórmula:C15H22N2O4SPureza:98.91%Forma y color:SolidPeso molecular:326.41Ifenprodil Tartrate
CAS:Ifenprodil is a selective NMDA receptor (glutamate) antagonist.Fórmula:C21H27NO2C4H6O6Pureza:99.02% - 99.55%Forma y color:SolidPeso molecular:400.49Apamin acetate
Apamin acetate: Selective Ca2+-activated K+ channel blocker, 18-amino acid bee venom peptide, promotes synapse repair, anti-inflammatory.Pureza:96.97%Forma y color:SolidAekatperone
Aekatperone, a reversible KATP channel inhibitor, exhibits an IC50 of 9 μM. It is utilized in research related to congenital hyperinsulinism (CHI).Fórmula:C20H25N5O2SForma y color:SolidPeso molecular:399.51Foslevcromakalim
CAS:Foslevcromakalim (QLS-101) is an KATP opener, converted to its active form by alkaline phosphatase in vivo, reduces intraocular pressure in normotensive mice.Fórmula:C16H19N2O6PForma y color:SolidPeso molecular:366.31Tertiapin
CAS:Tertiapin (reduced) is a synthetic bee venom peptide characterized by disulfide bonds between Cys3-Cys14 and Cys5-Cys18. It acts as an inhibitor of inward-rectifying potassium channels (potassium Channel) and can also block the activity of calcium-activated large conductance potassium channels. Tertiapin (reduced) is utilized in research related to diseases such as rheumatoid arthritis and multiple sclerosis.Fórmula:C106H180N34O23S5Forma y color:SolidPeso molecular:2459.1Phe-Met-Arg-Phe amide trifluoroacetate
CAS:Phe-met-arg-phe amide trifluoroacetate is an activator of K+ current with an ED50 of 23nm on the fundus nerve.Fórmula:C33H44F6N8O8SPureza:98%Forma y color:SolidPeso molecular:826.81Ebio2
Ebio2 is an effective activator of KCNQ2.Fórmula:C17H19F2N3O2Forma y color:SolidPeso molecular:335.349MASP-2-IN-1
MASP-2-IN-1 (Compound 77) is an inhibitor of mannan-binding lectin-associated serine proteases (MASP), specifically targeting MASP2 and MASP3, with IC50 values of 11.4 nM and 13.2 µM, respectively. It shows weak inhibitory activity on hERG with an IC50 of 175 µM. This compound exhibits poor stability in mouse plasma, with a half-life of 4.4 hours.Fórmula:C22H21N7O3SForma y color:SolidPeso molecular:463.512ShK-Dap22
CAS:Potent KV1.3 channel blocker; Kd 23 pM; selective; inhibits T cell activation; IC50 < 500 pM for mKV1.3.Fórmula:C166H268N54O48S7Pureza:98%Forma y color:SolidPeso molecular:4012.7ADWX 1
<p>Potent KV1.3 blocker, IC50: 0.0019 nM; less effective on KV1.1. Curbs CD4+ T cell activation; eases rat multiple sclerosis model.</p>Fórmula:C169H281N57O46S7Pureza:98%Forma y color:SolidPeso molecular:4071.86Iberiotoxin
CAS:<p>Selective blocker of the big conductance Ca2+-activated K+ channel.</p>Fórmula:C179H274N50O55S7Pureza:98%Forma y color:SolidPeso molecular:4230Lei-Dab7 TFA
Lei-Dab7 TFA blocks SK2 channels with 3.8 nM affinity, is >200x selective, and enhances LTP in rat hippocampus.Fórmula:C143H237F3N46O41S6Forma y color:SolidPeso molecular:3506.08Potassium Channel Targeted Library
A unique collection of xnum potassium channel blockers and agonists for high throughput and high content screening;Forma y color:Odour SolidPhe-Met-Arg-Phe, amide
CAS:Phe-Met-Arg-Phe amide activates K+ current in neurons (ED50=23 nM), co-localizes with neuropeptide Y in brain regions.Fórmula:C29H42N8O4SPureza:98%Forma y color:SolidPeso molecular:598.76RU-TRAAK-2
CAS:<p>RU-TRAAK-2 reversibly inhibits TWIK-related K+ channel, inactive on Kv1.2, GIRK2, Slo1.</p>Fórmula:C19H17N3OSPureza:99.81%Forma y color:SolidPeso molecular:335.42
