Canal de cloruro

T16Ainh-A01 is a potent inhibitor of TMEM16A Chloride channel, inhibiting TMEM16A-mediated chloride currents (IC50 of …

Betaine hydrochloride is an acidic form of betaine, a vitamin-like substance observed in grains and …

Niflumic acid is a Ca2+-activated Cl- channel blocker and an analgesic and anti-inflammatory agent used …

Eact is a selective and potent TMEM16A activator. It directly activates the TRPV1 channels in …

Urethane was an antineoplastic agent .Now is used for other medicinal purposes.

Afoxolaner is an isoxazoline insecticide/acaricide against Ixodes scapularis in dogs. Afoxolaner acts on the insect …

Halothane is a nonflammable, halogenated, hydrocarbon anesthetic that provides relatively rapid induction with little or …

Flufenamic acid is an anthranilic acid derivative with analgesic, anti-inflammatory, and antipyretic properties. It is …

DCPIB, a known specific and potent inhibitor of volume-regulated anion channels (VRAC),DCPIB displayed superior selectivity …

Endovion is a pharmacological anion channel and an Anoctamin-1 (ANO 1) channel inhibitor. Endovion is …

Meticrane is a sulphonamide-derivative with thiazide-like diuretic activity.

NS1652 is an anion conductance inhibitor. NS1652 blocks chloride channel has an IC50 of 1.6 …

Shikonin is an TMEM16A chloride channel inhibitor (IC50: 6.5 μM). Shikonin is also a selective …

Ani9 is a high selective blocker of Anoctamin1 (ANO1)/transmembrane protein 16A (TMEM16A) with an IC50 …

Picrotoxinin is a blocker of chloride channel and a noncompetitive antagonist of GABAA with an …

R(+)-IAA-94 is a potent indanyloxyacetic acid blocker of epithelial chloride channels. R(+)-IAA-94 inhibits Nef-sdAb19 (single-domain …

Picrotin is an inhibitor of glycine receptors. Picrotin blocks α2 GlyR, α1 GlyR, and α3 …

Selamectin is a macrocyclic lactone derivative of ivermectin, an anthelmintic that potentiates glutamate- and GABA-gated …

Alanine is a nonessential amino acid made in the body from the conversion of the …

Hypotaurine, an intermediate in taurine biosynthesis from cysteine in astrocytes, is an endogenous inhibitory amino …

Org 25543 is the development of an N-Acyl amino acid that selectively inhibits the glycine …

Guanidinoethyl sulfonate is a competitive glycine receptor antagonist.

MONNA is a potent TMEM16A (Anoctamin-1) blocker (IC50 : 80 nM). It induces vasorelaxation of …

Fenamic acid is a chloride channel blocker that causes renal papillary necrosis in rats. Fenamic …

Irisolidone is a potent volume-regulated anion channel (VRAC) current inhibitor, it exhibits high efficacy for …

CaCCinh-A01 is an inhibitor of the calcium-activated chloride channel (CaCC, 10 μM) and TMEM16A (IC50: …

Adjudin is a small molecule compound known to possess antispermatogenic function, attenuates microglia activation by …

Talniflumate is a calcium-activated chloride channel (hCLCA1/mCLCA3) blocker that reduces mucin synthesis and releases in …

NPPB is a chloride channel blocker with IC50 of 80 nM .

Lubiprostone, an activator of ClC-2 chloride channels, is used in the therapy of idiopathic chronic …