ATPasa

Prilocaine hydrochloride is a local anesthetic of the amino amide type, binds to voltage-gated sodium …

Digitoxin is an effective Na+/K+-ATPase inhibitor (EC50 value: 0.78 μM).

Suloctidil is a peripheral vasodilator that was formerly used in the management of peripheral and …

Trichlormethiazide is a short-acting, 3-dichloromethyl derivative of hydrochlorothiazide, belonging to the class of thiazide diuretics. …

Chlorpropamide is a sulfonylurea hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not …

Diazoxide is a benzothiadiazine derivative that is a peripheral vasodilator used for hypertensive emergencies. It …

Ciclopirox Olamine is a broad-spectrum antifungal agent with additional antibacterial and anti-inflammatory activities.

Fenbufen is a non-steroidal anti-inflammatory drug used primarily to treat inflammation in osteoarthritis, ankylosing spondylitis, …

Ciliobrevin D is a AAA+ ATPase motor cytoplasmic dynein inhibitor. Ciliobrevin D inhibits Hedgehog (Hh) …

Clorsulon is utilized for the treatment of Fasciola hepatica infections in calves and sheep.

Gboxin is an inhibitor of oxidative phosphorylation that targets glioblastoma,inhibits the activity of F0F1 ATP …

A cardiac glycoside that inhibits Na(+)/K(+) ATPase. It regulates transcription of MDR (increase, Pgp) and …

ATP synthase inhibitor 1 is an inhibitor of the c subunit of the F1/FO-ATP synthase …

Ciclopirox exerts its action by binding to and chelating trivalent cations, such as Fe3+ and …

Sodium oleate (Oleic acid sodium) is an abundant monounsaturated fatty acid sodium. Sodium oleate is …

PF 3716556, an effective and specific P-CAB (potassium-competitive acid blocker), is utilized for the treatment …

Asebogenin has anti-bacterial activity, it shows inhibitory activity against S. aureus and methicillin-resistant S. aureus …

WAY-606012 is a proprietary compound in the guanidine - based F1F0-ATPase inhibitor family.

Tiludronate disodium is an osteoclast vacuolar H(+)-ATPase inhibitor with antiresorptive and anti-inflammatory properties. Tiludronate disodium …

Sudoterb, also known as LL3858, is an anti-tubercular drug candidate.

Zeorin shows strong inhibition activity against bacteria and fungi. It markedly exhibits inhibitory activity on …

Cycloartane-3,24,25-triol has potential for development as an anti-cancer agent against prostate cancer. It reduces the …

(-)-Praeruptorin A has anti-inflammatory, anti-contractile and anti-hyperplasia activities, it exerts distinct relaxant effects on isolated …

Isokaempferide shows hepatoprotective, antiproliferative, and anti-inflammatory effects, the anti-inflammatory effects can be explained, at least …

Cabraleadiol displays antimycobacterial activity against Mycobacterium tuberculosis, it also is weakly cytotoxic to a breast …

Stauntosaponin A and stauntosaponin B show moderate inhibitory activities against Na+/K+-ATPase with IC50 values of …

Dihydroisotanshinone I has protective action against menadione-induced hepatotoxicity, attributed to its antioxidant properties including the …

Chalepensin behaves as an energy transfer inhibitor at low concentration, it inhibits multiple P450s and …

Ticlopidine is an antiplatelet drug in the thienopyridine family which is an adenosine diphosphate (ADP) …

Encecalin and demethylencecalin are major phytotoxic compounds isolated from Helianthella quinquenervis (Hook) A Gray (Asteraceae), …

4-Hydroxycinnamamide has antioxidant activity. 4-Hydroxycinnamamide derivatives are specific inhibitors of tyrosine-specific protein kinases.

3-Hydroxybakuchiol exerts cytotoxic and anti-proliferative effects on the TA3/Ha mouse mammary adenocarcinoma cell line and …

Ecdysone is a major steroid hormone in insects and herbs. Ecdysone triggers mineralocorticoid receptor activation …

Isopulegol presents depressant- and anxiolytic-like effects, it also has anticonvulsant and bioprotective effects against PTZ-induced …

Gossypetin has anti-mutagenic, anti-atherosclerotic, antioxidant, as well as cytoprotective and antimicrobial effects, it inhibits bone …

Lasiodiplodin may have potential anti-inflammatory activity, it shows moderate suppression effects on induced NO production. …

(-)-Denudatin B is derived from Magnolia fargesii. (-)-Denudatin B has nonspecific antiplatelet action at high …

Thevetin B is a cardiac glycoside and an inhibitor of Na+-, K+-dependent adenosinetriphosphatase (Na+,K+-ATPase) from …

Odoroside H has anticancer activities, the cytotoxic effects are induced by the inhibition of the …

Goniothalamin induces apoptosis in various cancer cell lines and has gastroprotective activity.

Marinobufagenin, a cardiotonic steroid, its increased concentrations are important in the cardiac disease and oxidant …

Retusin is derived from the leaves of Talinum triangulare. Retusin Retusin can be used in …

Echinatin exerts a protective effect against ischemia/reperfusion (I/R)-induced myocardial injury on hearts, this effect may …

5,2',6'-Trihydroxy-6,7,8-trimethoxyflavone (ED 50 =4.5 ug/ml ) shows cytotoxicity against L1210 cell and has inhibiting effects …

Cytochalasin D is an actin inhibitor, the removal of actin stress fibers is crucial for …

Wilfordine is an insecticidally active alkaloid, Na+-K+-ATPase may be an acting target of wilfordine against …

Matairesinol has radical and superoxide scavenging activities,; it also has anti-angiogenic activity by suppressing mROS …

FR-167356 is a specific inhibitor of a3 isoform vacuolar type H⁺-ATPase with IC50s of 170 …

Omecamtiv Mecarbil has been used in trials studying the treatment and basic science of Heart …

Phlorizin is a non-selective SGLT inhibitor found in apple, for hSGLT1( Ki=300 nM) and hSGLT2( …

1. Acevaltrate displays high cytotoxicity against GLC(4), a human small-cell lung cancer cell line, and …

Cinobufagin is a selective Na+/K+-ATPase inhibitor. The activity of Cinobufagin is same as ouabain.

Chloroprocaine HCl is a local anesthetic during surgical procedures.

NPD8733 is an inhibitor of cancer cell-enhanced fibroblast migration. It specifically binds to valosin-containing protein …

Brefeldin A , a Penicillium brefeldianum metabolite, which is a macrocyclic lactone exhibiting a wide …

Disodium (R)-2-Hydroxyglutarate is a competitive inhibitor of α-ketoglutarate-dependent dioxygenases with Ki of 0.628 mM.

7,3',4'-Trihydroxyflavone inhibits osteoclastogenesis via the nuclear factor of activated T cells c1. 7,3',4'-Trihydroxyflavone can markedly …

BTS is a potent inhibitor of Ca2+-stimulated myosin S1 ATPase (IC50 : 5 μM) .

Strophanthidin can induce calcium overload in vivo.

1. Oleandrin, the principal cardiac glycoside component of PBI-524, can quantitatively account for regulation of …

Chebulinic acid is a potent inhibitor of M. tuberculosis DNA gyrase. It also can inhibit …

Prilocaine is a local anesthetic of the amino amide type, which acts on the sodium …

Bacoside A3 is one of the components of Bacopa monnieri (L.) Wettst. bacoside A with …

Diphyllin could be characterized as a new V-ATPase inhibitor in treating gastric cancer and inhibiting …

Tirofiban hydrochloride monohydrate is a potent non-peptide, glycoprotein IIb/IIIa (integrins alphaIIbbetaIII) antagonist.

BRITE 338733 is a novel inhibitor of ATPase. BRITE 338733 inhibits the expression of RecA …