ATPasa
Las ATPasas son enzimas que catalizan la descomposición del ATP en ADP y un ion fosfato libre, una reacción que libera energía utilizada para impulsar muchos procesos dentro de la célula, incluido el transporte activo a través de las membranas. Las ATPasas juegan un papel crucial en el mantenimiento de la homeostasis celular, el equilibrio del pH y los gradientes de iones. Las disfunciones en la actividad de las ATPasas están asociadas con enfermedades como insuficiencia cardíaca, hipertensión y neurodegeneración. En CymitQuimica, ofrecemos inhibidores y moduladores de ATPasa de alta calidad para apoyar su investigación en energética celular, transporte de membranas y patología de enfermedades.
Se han encontrado 92 productos para "ATPasa".
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Diazoxide
CAS:Diazoxide (Proglycem) is a benzothiadiazine derivative that is a peripheral vasodilator used for hypertensive emergencies.Fórmula:C8H7ClN2O2SPureza:99% - 99.83%Forma y color:SolidPeso molecular:230.67Ciliobrevin D
CAS:Ciliobrevin D is a AAA+ ATPase motor cytoplasmic dynein inhibitor.Fórmula:C17H8Cl3N3O2Pureza:98.09%Forma y color:Orange SolidPeso molecular:392.62Ref: TM-T14965
1mg60,00€2mg87,00€5mg133,00€1mL*10mM (DMSO)148,00€10mg203,00€25mg401,00€50mg592,00€100mg827,00€Trichlormethiazide
CAS:Trichlormethiazide (Naqua) is a short-acting, 3-dichloromethyl derivative of hydrochlorothiazide, belonging to the class of thiazide diuretics.Fórmula:C8H8Cl3N3O4S2Pureza:98.8% - 99.54%Forma y color:White SolidPeso molecular:380.66Tolbutamide
CAS:Tolbutamide (HLS 831) is a sulphonylurea hypoglycemic agent with actions and uses similar to those of CHLORPROPAMIDE.Fórmula:C12H18N2O3SPureza:99.80% - 99.93%Forma y color:White Crystalline PowderPeso molecular:270.35Gboxin
CAS:Gboxin is an inhibitor of oxidative phosphorylation that targets glioblastoma,inhibits the activity of F0F1 ATP synthase, with antitumour activity.Fórmula:C22H33ClN2O2Pureza:99.96% - >99.99%Forma y color:SolidPeso molecular:392.96Ref: TM-T15373
1mg42,00€2mg55,00€1mL*10mM (DMSO)87,00€5mg88,00€10mg126,00€25mg245,00€50mg385,00€100mg612,00€200mg850,00€Fenbufen
CAS:Fenbufen (Lederfen) is a non-steroidal anti-inflammatory drug used primarily to treat inflammation in osteoarthritis, ankylosing spondylitis, and tendinitis.Fórmula:C16H14O3Pureza:98.35% - 98.74%Forma y color:White SolidPeso molecular:254.28ATP synthase inhibitor 1
CAS:ATP synthase inhibitor 1 is an inhibitor of the c subunit of the F1/FO-ATP synthase complex.Fórmula:C17H18ClN3O3S2Pureza:99.83%Forma y color:SolidPeso molecular:411.93Prilocaine hydrochloride
CAS:Prilocaine HCl: local amino amide anesthetic, blocks voltage-gated sodium channels in neurons, inhibits Na+ permeability.Fórmula:C13H21ClN2OPureza:99.97%Forma y color:SolidPeso molecular:256.77Suloctidil
CAS:Suloctidil is a peripheral vasodilator that was formerly used in the management of peripheral and cerebral vascular disorders.Fórmula:C20H35NOSPureza:99.75% - >99.99%Forma y color:White SolidPeso molecular:337.56LC-MF-4
LC-MF-4 is a selective FGFR3 PROTAC degrader with a DC50 of 30.89 nM in KMS-11 cells. It inhibits the metabolic functions of FGFR3-TACC3 fusion-positive cancers by reducing ATP synthesis and suppressing mitochondrial biogenesis genes. LC-MF-4 demonstrates potent anti-tumor activity in the Ba/F3-FGFR3-TACC3 xenograft mouse model and is applicable for research on FGFR3 gene mutation cancers such as bladder cancer and urothelial carcinoma (UC).Forma y color:Odour SolidS-WJM992
S-WJM992 (compound 10ahb) serves as an antiparasitic agent, effectively inhibiting ATPase activity in high [Na+] environments. It also significantly counteracts parasites resistant to PfATP4 inhibitors. Additionally, S-WJM992 acts as a potential transmission blocker by impeding gamete development and halting the transmission of parasites to mosquitoes during blood feeding.Fórmula:C22H18ClFN6O3Forma y color:SolidPeso molecular:468.87NSC799462
NSC799462, a triazole inhibitor, specifically targets p97 ATPase, exerting its effect by binding to a designated site on the p97 enzyme. This interaction induces localized structural alterations in p97, effectively inhibiting its ATPase activity with an IC 50 value of 15 nM.Fórmula:C30H32F2N6O3SForma y color:SolidPeso molecular:594.68Cyclocreatine
CAS:Cyclocreatine, a creatine analogue and substrate for creatine kinase, inhibits creatine metabolism and prostate cancer cell proliferation.Fórmula:C5H9N3O2Pureza:99.86%Forma y color:White SolidPeso molecular:143.14Chlorpropylate
CAS:Chlorpropylate is an insecticide.Fórmula:C17H16Cl2O3Pureza:98%Forma y color:SolidPeso molecular:339.21(S)-PF-03716556
CAS:(S)-PF-03716556 can be used as an acid pump inhibitor for the treatment of disease conditions mediated by acid pump inhibitory activity.Fórmula:C22H26N4O3Pureza:99.75% - 99.91%Forma y color:White SolidPeso molecular:394.47Transdermal Peptide Disulfide
CAS:TD 1 peptide, an 11-amino acid, binds ATP1B1's C-terminus, enhancing transdermal drug delivery.Fórmula:C40H64N14O16S2Pureza:98%Forma y color:SolidPeso molecular:1061.15(±)16-HETE
CAS:Electrolyte and fluid transport in the kidney are regulated in part by arachidonic acid and its metabolites.Fórmula:C20H32O3Forma y color:SolidPeso molecular:320.473PROTAC EGFR degrader 15
PROTACEGFRdegrader 15 is a bifunctional EGFR PROTAC degrader composed of Pomalidomide and Gefitinib. It facilitates EGFR degradation through ubiquitin-proteasome dependent proteolysis and autophagic-lysosomal pathways. Additionally, PROTACEGFRdegrader 15 targets ETFA to enhance ATP production. It significantly suppresses tumor growth in Gefitinib-resistant HCC-827 xenograft models.17(S)-HETE
CAS:17(S)-HETE is an arachidonic acid metabolite generated via the CYP450 pathway. 17(S)-HETE acts as an allosteric activator of CYP450 1B1 and an ATPase inhibitor.Fórmula:C20H32O3Forma y color:Transparent LiquidPeso molecular:320.47(±)17-HETE
CAS:Electrolyte and fluid transport in the kidney are regulated in part by arachidonic acid and its metabolites.Fórmula:C20H32O3Forma y color:SolidPeso molecular:320.473ATP Synthesis-IN-1
ATP Synthesis-IN-1 (Compound 4), a quinoline derivative, potently inhibits PA ATP synthesis with an IC50 of 11.1μg/mL and exhibits antibacterial properties.Forma y color:Odour SolidSC 4453
CAS:SC 4453 is a digoxin analog and a cardiac glycoside derivative.Fórmula:C41H64N2O12Forma y color:SolidPeso molecular:776.965Digoxigenin Monodigitoxoside
CAS:Digoxigenin monodigitoxoside is a cardiac glycoside metabolite of digoxin and a Na+/K+ ATPase inhibitor.Fórmula:C29H44O8Forma y color:SolidPeso molecular:520.663Prilocaine acetate
Prilocaine acetate, an amino amide compound, functions as a Na/K-ATPase inhibitor, exhibiting neurotoxic effects [1] [2].Fórmula:C15H24N2O3Forma y color:SolidPeso molecular:280.36PK095
CAS:PK095 is a proprietary compound in the guanidine - based F1F0-ATPase inhibitor family.Fórmula:C20H18N4O2SPureza:97.06%Forma y color:SolidPeso molecular:378.45Ref: TM-T67763
1mg64,00€5mg136,00€1mL*10mM (DMSO)138,00€10mg187,00€25mg298,00€50mg411,00€100mg555,00€200mg743,00€BMS 199264
CAS:BMS 199264 hydrochlorid a inhibitor of mitochondrial F1F0 ATP hydrolase, thus preventing ATP reduction to ameliorate cardiac necrosis during ischemia.Fórmula:C26H31ClN4O4SPureza:99.83%Forma y color:SolidPeso molecular:531.07NSC819701
NSC819701 is a triazole-based inhibitor of p97ATPase. It inhibits the activity of p97ATPase by binding to specific sites on p97.Fórmula:C30H32F2N8O3SForma y color:SolidPeso molecular:622.69P259
P259 is a Drp1-Mff inhibitor that selectively impedes the interaction between Drp1 and Mff, thereby differentiating physiological fission from pathological fission. It leads to mitochondrial elongation and impairs mitochondrial function and motility. P259 reduces ATP levels in the brain, alters mitochondrial structure, induces behavioral defects in wild-type mice, and shortens the lifespan of Huntington's disease (HD) model mice.Forma y color:Odour SolidLnd 623
CAS:Lnd 623 is an inotropic aminosteroid.Fórmula:C27H47NO6Forma y color:SolidPeso molecular:481.674Flavopereirine
CAS:Flavopereirine is a beta-carboline alkaloid.Fórmula:C17H15N2Forma y color:SolidPeso molecular:247.315-Hydroxydecanoic acid
CAS:5-Hydroxydecanoic acid is a selective ATP-sensitive K+ (KATP) channel blocker (IC50 of ~30 μM). 5-Hydroxydecanoic acid is a substrate for mitochondrial outer membrane acyl-CoA synthetase and has antioxidant activity.Fórmula:C10H20O3Pureza:99.24%Forma y color:White SolidPeso molecular:188.26Anti-ATP7B Antibody (4W208)
Anti-ATP7B Antibody (4W208) is an antibody targeting ATP7B. Anti-ATP7B Antibody (4W208) can be used in ELISA, IHC, IF, FCM.Forma y color:Odour LiquidAnti-ATP7B Antibody (7M703)
Anti-ATP7B Antibody (7M703) is an antibody targeting ATP7B. Anti-ATP7B Antibody (7M703) can be used in ELISA, IF, FCM.Forma y color:Odour Liquid1-N-Methyl-4-mercaptohistidine disulfide
CAS:1-N-Methyl-4-mercaptohistidine disulfide is a Duchenne chloroplast coupling factor 1 redox modulator that inhibits light-triggered CF1 ATPase activity.Fórmula:C14H20N6O4S2Pureza:97.67% - ≥98%Forma y color:SolidPeso molecular:400.48L-Palmitoylcarnitine
CAS:L-Palmitoylcarnitine (L-PC) inhibits Na/K ATPase activity and potentiates fibrinolytic enzymes and tPA to inhibit thrombosis.Fórmula:C23H45NO4Pureza:97% - 99.81%Forma y color:SolidPeso molecular:399.61(+)-SJ733
CAS:(+)-SJ733 (SJ000557733) is a potent Na+-ATPase PfATP4 inhibitor with antimalarial activity for the study of malaria.Fórmula:C24H16F4N4O2Pureza:99.21% - 99.76%Forma y color:White SolidPeso molecular:468.4Ref: TM-T17313
1mg145,00€5mg423,00€1mL*10mM (DMSO)437,00€10mg647,00€25mg1.009,00€50mg1.341,00€100mg1.783,00€Transdermal Peptide Disulfide Acetate
Transdermal Peptide acetate(888486-23-5 free base) (TD 1 (peptide) acetate) is a 11-amino acid peptide, binds toNa+/K+-ATPase beta-subunit (ATP1B1), and mainlyFórmula:C42H68N14O18S2Pureza:99.97%Forma y color:SolidPeso molecular:1121.2Omecamtiv mecarbil
CAS:Omecamtiv mecarbil (CK-1827452) has been used in trials studying the treatment and basic science of Heart Failure, Echocardiogram, Pharmacokinetics, ChronicFórmula:C20H24FN5O3Pureza:98% - 99.23%Forma y color:SolidPeso molecular:401.43(-)-Blebbistatin
CAS:(-)-Blebbistatin ((S)-(-)-Blebbistatin) is an S enantiomer of blebbistatin. It is a potent and selective myosin II inhibitor with IC50 ranging from 0.5 to 5 μM.Fórmula:C18H16N2O2Pureza:99.38% - 99.61%Forma y color:Yellow SolidPeso molecular:292.33BTB06584
CAS:BTB06584: IF1-dependent F1 Fo-ATPase inhibitor; novel AHAS inhibitor targeting MTB.Fórmula:C19H12ClNO6SPureza:99.90% - ≥95%Forma y color:White SolidPeso molecular:417.82Ref: TM-T1940
2mg34,00€5mg50,00€1mL*10mM (DMSO)56,00€10mg70,00€25mg92,00€50mg116,00€100mg202,00€200mg314,00€NSC 617145
CAS:NSC 617145 (NSC617145) is an inhibitor of WRN helicase that inhibits the ATPase, but not exonuclease, activity of WRN helicase in a concentration-dependentFórmula:C13H10Cl4N2O4Pureza:99.78%Forma y color:Yellow SolidPeso molecular:400.04Ref: TM-T9168
1mg34,00€2mg49,00€5mg73,00€1mL*10mM (DMSO)80,00€10mg90,00€25mg164,00€50mg227,00€100mg358,00€500mg842,00€Eniporide
CAS:Eniporide is a Na(+)/H(+) exchange inhibitor.Fórmula:C14H16N4O3SPureza:96.78% - 99.26%Forma y color:Yellow SolidPeso molecular:320.37Ref: TM-T2089
1mg34,00€5mg73,00€1mL*10mM (DMSO)84,00€10mg113,00€25mg187,00€50mg279,00€100mg404,00€200mg570,00€BTS
CAS:BTS (N-Tosylbenzylamine) is a potent inhibitor of Ca2+-stimulated myosin S1 ATPase (IC50 : 5 μM) .Fórmula:C14H15NO2SPureza:99.45%Forma y color:White Crystalline SolidPeso molecular:261.34Rabeprazole sodium
CAS:Rabeprazole sodium treats stomach ulcers and Zollinger-Ellison syndrome, blocking ATPase in gastric cells.Fórmula:C18H20N3NaO3SPureza:98% - 99.91%Forma y color:White SolidPeso molecular:381.42Esomeprazole Magnesium
CAS:Esomeprazole Magnesium (NEXIUM) is the S-isomer of omeprazole, can reduce gastric acid secretion with selective and irreversible proton pump inhibitor activity.Fórmula:C34H36MgN6O6S2Pureza:98.76% - 99.73%Forma y color:SolidPeso molecular:713.12Mitiglinide Calcium
CAS:Mitiglinide Calcium (KAD-1229) is a blood glucose-lowering drugs, stimulating insulin secretion by closing the ATP-sensitive K+ channels in pancreatic beta-Fórmula:(C19H24NO3)2·CaPureza:99.83%Forma y color:SolidPeso molecular:668.88Rbin-1
CAS:Rbin-1 (Ribozinoindole-1) is a potent,specific inhibitor of eukaryotic ribosome biogenesis.Fórmula:C13H12N4SPureza:99.83%Forma y color:White SolidPeso molecular:256.33Prilocaine
CAS:Prilocaine (NSC-40027) is a local anesthetic of the amino amide type, which acts on the sodium channel on the neuronal membrane and limits the spread ofFórmula:C13H20N2OPureza:98.49%Forma y color:SolidPeso molecular:220.31Tenatoprazole
CAS:Tenatoprazole (TU-199), a prodrug of the proton pump inhibitor (PPI) class, can inhibit proton transport (IC50: 3.2 μM).Fórmula:C16H18N4O3SPureza:99.57%Forma y color:White Crystalline PowderPeso molecular:346.4Chloroprocaine hydrochloride
CAS:Chloroprocaine hydrochloride (Chloroprocaine HCl) is a local anesthetic during surgical procedures.Fórmula:C13H20Cl2N2O2Pureza:99.65%Forma y color:SolidPeso molecular:307.22
