ATPasa
Las ATPasas son enzimas que catalizan la descomposición del ATP en ADP y un ion fosfato libre, una reacción que libera energía utilizada para impulsar muchos procesos dentro de la célula, incluido el transporte activo a través de las membranas. Las ATPasas juegan un papel crucial en el mantenimiento de la homeostasis celular, el equilibrio del pH y los gradientes de iones. Las disfunciones en la actividad de las ATPasas están asociadas con enfermedades como insuficiencia cardíaca, hipertensión y neurodegeneración. En CymitQuimica, ofrecemos inhibidores y moduladores de ATPasa de alta calidad para apoyar su investigación en energética celular, transporte de membranas y patología de enfermedades.
Se han encontrado 98 productos para "ATPasa".
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Istaroxime hydrochloride
CAS:Istaroxime hydrochloride (PST2744 hydrochloride) is a Na+/K+-ATPase inhibitor and SERCA 2 activator, and is a novel positive inotropic compound.Fórmula:C21H33ClN2O3Forma y color:White SolidPeso molecular:396.95Istaroxime
CAS:Istaroxime is an effective inhibitor of Na+, K+-ATPase (IC50: 0.11 μM).Fórmula:C21H32N2O3Pureza:98%Forma y color:SolidPeso molecular:360.49RS 029
CAS:RS 029 is a nitroimidazole that has been exhibited to significantly inhibit (Na+K+) ATP-ase activity.Fórmula:C13H16N6O6Pureza:98%Forma y color:SolidPeso molecular:352.3SKF-97574 HCl
CAS:SKF-97574 is proton pump inhibitor.Fórmula:C22H25ClN2O3Pureza:98%Forma y color:SolidPeso molecular:400.9AGN-201904
CAS:AGN-201904 is a proton pump inhibitor, an omeprazole prodrug, which delays aging and may be used for the prevention and treatment of peptic ulcers.Fórmula:C25H25N3O8S2Pureza:97.32%Forma y color:SolidPeso molecular:559.61NC-1300-B
CAS:NC-1300-B inhibits H(+)-K(+)-ATPase and is used in the study of gastric ulcers.Fórmula:C17H19N3OSPureza:98.07%Forma y color:SolidPeso molecular:313.42SKF96067
CAS:SKF96067 is a reversible gastric H+/K+-ATPase inhibitor that can induce relaxation of human airway smooth muscle in vitro.Fórmula:C21H22N2O2Pureza:99.89%Forma y color:SolidPeso molecular:334.41Leminoprazole
CAS:Leminoprazole is an orally available H+,K(+)-ATPase inhibitor that protects gastric mucosal cells from various cellular damages.Fórmula:C19H23N3OSPureza:99.77% - 99.79%Forma y color:SolidPeso molecular:341.47FR-167356
CAS:FR-167356 inhibits a3 isoform H⁺-ATPase (IC50: 170-370 nM), targeting osteoclasts, kidneys, macrophages; reduces B16-F10 bone metastasis.Fórmula:C19H17Cl2NO3Pureza:98.44% - 99.74%Forma y color:Yellow SolidPeso molecular:378.25SCH28080
CAS:SCH28080 is a reversible and K+-competitive inhibitor of gastric H+/K+-ATPase with an IC50 value of 20 nM (rabbit microsomal membrane).SCH28080 is a potentFórmula:C17H15N3OPureza:99.24%Forma y color:Yellow SolidPeso molecular:277.32Tiludronate disodium
CAS:Tiludronate disodium: osteoclast inhibitor for metabolic bone disorder research.Fórmula:C7H7ClNa2O6P2SPureza:>99.99% - >99.99%Forma y color:White SolidPeso molecular:362.57Ro 18-5364
CAS:Ro 18-5364 is a potent inhibitor of the gastric (H+ + K+)-ATPase with an apparent Ki of 0.1 μM at pH 6.Fórmula:C22H25N3O3SPureza:98%Forma y color:SolidPeso molecular:411.523′-Acetate-ATP
CAS:3’-Acetate-ATP, an analogue of ATP and its acetylation product, exhibits maximum ultraviolet absorption at 259 nm in neutral aqueous solutions.Fórmula:C12H18N5O14P3Forma y color:SolidPeso molecular:549.22BMS-199264 hydrochloride
CAS:BMS-199264 hydrochloride is selective inhibitor of mitochondrial F1F0 ATP hydrolase,inhibit decline of ATP and myocardial necrosis during myocardial ischemia.Fórmula:C26H32Cl2N4O4SPureza:99.86%Forma y color:SolidPeso molecular:567.53Antimalarial agent 7
Antimalarial agent 7 is a potent and effective inhibitor of PfATP4. Antimalarial agent 7 has potential for the study of the human plasmodium falciparum.Fórmula:C23H22F2N4O3Forma y color:SolidPeso molecular:440.44ATP synthase inhibitor 2
CAS:ATP synthase inhibitor 2 blocks P. aeruginosa ATP synthase; IC50=10 μg/mL, fully inhibits at 128 μg/mL.Fórmula:C21H22N2O3SForma y color:White SolidPeso molecular:382.48Hsp90-IN-38
CAS:Hsp90-IN-38 (compound 20m) is an inhibitor of HSP90 (heat shock protein). It demonstrates a strong binding affinity to HSP90 with a Kd of 87 nM. The compound inhibits ATPase activity with an IC50 of 0.13 μM. Hsp90-IN-38 also shows inhibitory effects on HCT116, MCF-7, SKBr3, K562, and A549 cells with IC50 values of 0.187, 0.072, 0.105, 0.403, and 0.031 μM, respectively.Fórmula:C28H35N3O5Forma y color:SolidPeso molecular:493.595Suloctidil HCl
CAS:Suloctidil HCl is a peripheral vascular dilator.Fórmula:C20H36ClNOSForma y color:SolidPeso molecular:374.02
