Cotransportador de Na-K-Cl
El cotransportador Na-K-Cl es una proteína de membrana que desempeña un papel fundamental en el mantenimiento del equilibrio electrolítico y el volumen celular al mover iones de sodio, potasio y cloruro a través de la membrana celular. Es especialmente importante en el funcionamiento de las células renales, donde contribuye a la regulación de la presión arterial y el equilibrio de líquidos. La disfunción de este transportador está asociada con hipertensión, trastornos renales y condiciones neurológicas. En CymitQuimica, ofrecemos una gama de moduladores dirigidos al cotransportador Na-K-Cl para apoyar su investigación en nefrología, salud cardiovascular y homeostasis iónica.
Se han encontrado 10 productos de "Cotransportador de Na-K-Cl"
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Azosemide
CAS:Azosemide is a potent NKCC1 inhibitor (IC50s: 0.246 µM and 0.197 µM for hNKCC1A and NKCC1B).Fórmula:C12H11ClN6O2S2Pureza:99.84%Forma y color:SolidPeso molecular:370.84Torsemide
CAS:Torsemide (AC-4464), a sulfonylurea loop diuretic, has a long action duration, high plasma protein binding, and a long half-life.Fórmula:C16H20N4O3SPureza:99.81%Forma y color:Crystalline SolidPeso molecular:348.42Bumetanide
CAS:Bumetanide (PF 1593) is a potent sulfamoylanthranilic acid derivative belonging to the class of loop diuretics. In the brain, bumetanide may prevent seizures in neonates by blocking the bumetanide-sensitive sodium-potassium-chloride cotransporter (NKCC1), thereby inhibiting chloride uptake thus, decreasing the internal chloride concentration in neurons and may block the excitatory effect of GABA in neonates.Fórmula:C17H20N2O5SPureza:99.82% - 99.9%Forma y color:SolidPeso molecular:364.42KCC2 potentiators-1
CAS:Compound 2, known as KCC2 potentiators-1, acts as an enhancer of the potassium chloride cotransporter-2 (KCC2). It holds potential for applications in studies related to neurological disorders.Fórmula:C15H17N3OSForma y color:SolidPeso molecular:287.38Torsemide (Standard)
CAS:Torsemide (Standard) is the standard substance of Torsemide, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Torsemide (AC-4464) is an anilinopyridine sulfonylurea belonging to the class of loop diuretics. Torsemide has a prolonged duration of action compared to other loop diuretics, is extensively protein bound in plasma and has a relatively long half-life.Fórmula:C16H20N4O3SPeso molecular:348.42Piretanide
CAS:Piretanide, an oral loop diuretic, effective and potassium-sparing, heart failure and hypertension with reduced electrolyte imbalance risk.Fórmula:C17H18N2O5SForma y color:Pale Yellow PowderPeso molecular:362.4ZT-1a
CAS:ZT-1a is a SPAK inhibitor.ZT-1a inhibits SPAK.ZT-1a can be used for the prevention and treatment of neurodegenerative and neurocognitive disorders.Fórmula:C22H15Cl3N2O2Pureza:99.77%Forma y color:SolidPeso molecular:445.73Bumetanide-d5
CAS:Bumetanide D5 is a deuterium-labeled Bumetanide. Bumetanide is a Na+-K+-Cl- (NKCC1) inhibitor (IC50s: 0.68 and 4.0 μM for hNKCC1A and hNKCC2A).Fórmula:C17H20N2O5SPureza:98%Forma y color:SolidPeso molecular:369.45ARN23746
CAS:ARN23746 is a NKCC1 Inhibitor for the Treatment of Core Symptoms in Down Syndrome.Fórmula:C17H25F3N2O4SForma y color:SolidPeso molecular:410.45Bumetanide sodium
CAS:Bumetanide sodium, a potent diuretic, blocks NKCC1 (IC50: 0.68 μM) and NKCC2 (IC50: 4.0 μM).Fórmula:C17H19N2NaO5SForma y color:SolidPeso molecular:386.4
